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Vaccines, Volume 9, Issue 12

December 2021 - 137 articles

Cover Story: The scarcity of alternative therapeutics against viral infections as efficient as vaccines makes them essential in such areas as animal care. Whole-pathogen inactivated vaccines present substantial biosafety and handling advantages and thus a higher market acceptance in the animal production industry, including in aquaculture. Viral nervous necrosis (VNN) caused by the nervous necrosis virus (NNV) affects a broad range of primarily marine fish species, with mass mortality rates among larvae and juveniles. Its genetic diversification may hinder the effective implementation of vaccines. The present study describes different rapid inactivation procedures for developing an inactivated vaccine against a new NNV isolate confirmed to possess deadly effects upon the European seabass (Dicentrarchus labrax), an important farmed fish species. View this paper
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Articles (137)

  • Review
  • Open Access
25 Citations
12,204 Views
15 Pages

20 December 2021

mRNA COVID-19 vaccines have hegemonized the world market, and their administration to the population promises to stop the pandemic. However, the waning of the humoral immune response, which does not seem to last so many months after the completion of...

  • Review
  • Open Access
33 Citations
9,176 Views
12 Pages

20 December 2021

The insect cell expression system has previously been proposed as the preferred biosecurity strategy for production of any vaccine, particularly for future influenza pandemic vaccines. The development and regulatory risk for new vaccine candidates is...

  • Article
  • Open Access
16 Citations
4,808 Views
17 Pages

Who Got Vaccinated for COVID-19? Evidence from Japan

  • Toshihiro Okubo,
  • Atsushi Inoue and
  • Kozue Sekijima

20 December 2021

Vaccination has been critical to reducing infections and deaths during the coronavirus disease 2019 (COVID-19) pandemic. While previous studies have investigated attitudes toward taking a vaccine, studies on the determinants of COVID-19 vaccination b...

  • Feature Paper
  • Article
  • Open Access
9 Citations
4,536 Views
16 Pages

Mycoplasma suis Alpha-Enolase Subunit Vaccine Induces an Immune Response in Experimental Animals

  • Shujiang Xue,
  • Kangseok Seo,
  • Miaosen Yang,
  • Chengdu Cui,
  • Meng Yang,
  • Siyu Xiang,
  • Zongbin Yan,
  • Shengjun Wu,
  • Jincheng Han and
  • Xiaoyang Yu
  • + 2 authors

20 December 2021

Recombinant protein technology has emerged as an excellent option for vaccine development. However, prior to our study, the immune induction ability of recombinant Mycoplasma suis alpha-enolase (rMseno) in animals remained unclear. The purpose of thi...

  • Review
  • Open Access
16 Citations
7,093 Views
16 Pages

Promising Expectations for Pneumococcal Vaccination during COVID-19

  • Hyobin Im,
  • Jinhui Ser,
  • Uk Sim and
  • Hoonsung Cho

20 December 2021

The emergence of new viral infections has increased over the decades. The novel virus is one such pathogen liable for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, popularly known as coronavirus disease 2019 (COVID-19). Most...

  • Article
  • Open Access
18 Citations
3,962 Views
11 Pages

20 December 2021

At the end of 2020, COVID-19 vaccination programs were initiated in many countries, including Poland. The first vaccine approved in Poland was the BNT162b2 mRNA preparation (Pfizer/BioNTech), and the first vaccinated group were healthcare workers. Th...

  • Article
  • Open Access
5 Citations
2,916 Views
8 Pages

20 December 2021

We observe that a residue R of the spike glycoprotein of SARS-CoV-2 that has mutated in one or more of the current variants of concern or interest, or under monitoring, rarely participates in a backbone hydrogen bond if R lies in the S1 subunit and u...

  • Article
  • Open Access
3 Citations
3,433 Views
18 Pages

20 December 2021

Collagen is the main component of the extracellular matrix (ECM) and might play an important role in tumor microenvironments. However, the relationship between collagen and clear cell renal cell cancer (ccRCC) is still not fully clarified. Hence, we...

  • Case Report
  • Open Access
19 Citations
7,906 Views
11 Pages

Chronic Inflammatory Demyelinating Polyneuropathy after ChAdOx1 nCoV-19 Vaccination

  • Caterina Francesca Bagella,
  • Davide G. Corda,
  • Pietro Zara,
  • Antonio Emanuele Elia,
  • Elisa Ruiu,
  • Elia Sechi and
  • Paolo Solla

19 December 2021

Recently several patients, who developed Guillain–Barré syndrome characterized by prominent bifacial weakness after ChAdOx1 nCoV-19 vaccination, were described from different centers. We recently observed a patient who developed a simila...

  • Review
  • Open Access
73 Citations
12,472 Views
25 Pages

Bacterial-Based Cancer Therapy (BBCT): Recent Advances, Current Challenges, and Future Prospects for Cancer Immunotherapy

  • Kajal H. Gupta,
  • Christina Nowicki,
  • Eileena F. Giurini,
  • Amanda L. Marzo and
  • Andrew Zloza

18 December 2021

Currently approximately 10 million people die each year due to cancer, and cancer is the cause of every sixth death worldwide. Tremendous efforts and progress have been made towards finding a cure for cancer. However, numerous challenges have been fa...

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Vaccines - ISSN 2076-393X