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Vaccines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Research on Neutralizing Antibody Response to SARS-CoV-2 Variants

edited by

Chloé Dimeglio

submission deadline 6 Aug 2025 | 2 articles | Viewed by 3555 | Submission Open

Keywords: SARS-CoV-2 and vaccines; SARS-CoV-2 and natural infection; immunity mechanism; competition between variants; SARS-CoV-2 dynamics

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Veterinary Vaccines and Host Immune Responses

edited by Ayumi Matsuyama-Kato and

Faizal Careem

submission deadline 13 Aug 2025 | 10 articles | Viewed by 11573 | Submission Open

Keywords: animal vaccine; vaccine delivery; immune response; adjuvant; antibody-mediated immunity; cell-mediated immunity; immunogenicity; veterinary immunology

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Acceptance and Coverage

edited by

Ryoko Sato

and

Christian Napoli

submission deadline 15 Aug 2025 | 2 articles | Viewed by 3549 | Submission Open

Keywords: vaccine; vaccination; vaccine acceptance; vaccine hesitancy; vaccination coverage; immunization coverage

(This special issue belongs to the Section Vaccines and Public Health)

Immune Correlates of Protection in Vaccines, 2nd Edition

edited by

Jingyou Yu

submission deadline 16 Aug 2025 | 2 articles | Viewed by 1913 | Submission Open

Keywords: vaccine; humoral immunity; cellular immunity; innate immunity; infectious disease; virus; cancer

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Impact of Immunization Safety Monitoring on Vaccine Coverage

edited by Jane F. Gidudu

submission deadline 25 Aug 2025 | 8 articles | Viewed by 11139 | Submission Open

Keywords: vaccine safety; immunization safety; adverse events following immunization; vaccination coverage; vaccine hesitancy; pharmacovigilance; information systems; active surveillance; mis- and dis-information

(This special issue belongs to the Section Vaccines and Public Health)

New Trends in Vaccine Characterization, Formulations, and Development

edited by

Ravinder Kumar

submission deadline 31 Aug 2025 | 12 articles | Viewed by 53374 | Submission Open

Keywords: vaccines; formulation; development; vaccine delivery; mRNA vaccines; DNA vaccines; subunit vaccine; adjuvant; yeast-based vaccines; virus-like particles (VLPs); surface display; production process; quality control

Biotechnologies Applied in Vaccine Research

edited by

Yuan-Chuan Chen

submission deadline 31 Aug 2025 | 5 articles | Viewed by 22950 | Submission Open

Keywords: vaccine; biotechnology; vector; nanoparticle; virus; bacteria; recombination DNA; mRNA; subunit; adjuvant; delivery

Strategies of Viral Vectors for Vaccine Development

edited by

Kathleen Hefferon

submission deadline 31 Aug 2025 | 7 articles | Viewed by 16617 | Submission Open

Keywords: vaccine; viral vector; virus-like particles

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Novel Vaccines and Vaccine Technologies for Emerging Infections

edited by

Wangxue Chen

Xuguang Li

and

Amine A. Kamen

submission deadline 31 Aug 2025 | 7 articles | Viewed by 15891 | Submission Open

Keywords: novel vaccines and adjuvant; universal vaccines; mucosal vaccines; emerging infections; antimicrobial resistance; systems vaccinology; vaccine production

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine Uptake in Italy, Through the OBVIOUS Project and Other Independent Research

edited by

Jacopo Lenzi

and

Davide Gori

submission deadline 31 Aug 2025 | 6 articles | Viewed by 14383 | Submission Open

Keywords: vaccine uptake; vaccine hesitancy; vaccination rates; Italy

(This special issue belongs to the Section Epidemiology and Vaccination)

Vaccines Targeting the Tumor Microenvironment: Challenges and Future Prospects

edited by

Walter J. Storkus

and Devin Lowe

submission deadline 31 Aug 2025 | 8 articles | Viewed by 13229 | Submission Open

Keywords: vaccine; adoptive cell therapy; CAR-T cells; immune checkpoint inhibitors; immunotherapy; stroma; tumor microenvironment

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Advancing the Science on Vaccine Hesitancy to Inform Interventions

edited by Kimberly H. Nguyen and

Jennifer Allen

submission deadline 31 Aug 2025 | 6 articles | Viewed by 11353 | Submission Open

Keywords: vaccine hesitancy; vaccine confidence; COVID-19; routinely recommended vaccines; epidemiologic methods; conceptual frameworks; strategies; surveillance

(This special issue belongs to the Section Vaccines and Public Health)

Advances in Glycoconjugate Vaccines and Nanovaccines

edited by

Marco Terreni

and

Sara Tengattini

submission deadline 31 Aug 2025 | 4 articles | Viewed by 11009 | Submission Open

Keywords: glycoconjugate vaccines; infection diseases; anticancer vaccines; glycosylated nanovaccines; antigenic saccharides; conjugation chemistry; glycoconjugate characterization; dual-acting vaccines; glycosylated nanoparticles

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Respiratory Syncytial Virus (RSV) Vaccine

edited by

Surender Khurana

submission deadline 31 Aug 2025 | 4 articles | Viewed by 10270 | Submission Open

Keywords: respiratory syncytial virus (RSV); RSV vaccine development; viral vector vaccines; subunit vaccines; prefusion protein design; mRNA vaccines; vaccine efficacy; immunization strategies

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Role of Gut Microbiota in Immune Tolerance and Vaccine Development

edited by

Sin-Hyeog Im

submission deadline 31 Aug 2025 | 2 articles | Viewed by 5988 | Submission Open

Keywords: immune tolerance; subtype of immune cells; microbiome; probiotics; T cells; B cells; dendritic cells; antigen-presenting cells

(This special issue belongs to the Section Vaccines, Clinical Advancement, and Associated Immunology)

Understanding Infectious Disease Vaccinations: Implications for Health and Safety

edited by

Daniel Kwasi Ahorsu

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3739 | Submission Open

Keywords: vaccination; infectious disease; health; wellbeing; knowledge; attitudes

(This special issue belongs to the Section Vaccines and Public Health)

Vaccination Against Vector-Borne Diseases: Bridging Public Health and Epidemiology

edited by

Angela Stufano

and

Claudia Maria Trombetta

submission deadline 31 Aug 2025 | 2 articles | Viewed by 2611 | Submission Open

Keywords: vector-borne diseases; vaccination strategies; epidemiology; public health integration; disease prevention

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Vaccine Hesitancy and Acceptance: A Public Health Perspective

edited by

Neli Ragina

and

Michael J. Conway

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1786 | Submission Open

Keywords: vaccine hesitancy; vaccine acceptance; public health; vaccine uptake; misinformation; risk perception; health communication; immunization rates; herd immunity; behavioral determinants; social determinants; trust in healthcare; vaccine misinformation; vaccine education; vaccine refusal; vaccine policy; health disparities

(This special issue belongs to the Section Vaccines and Public Health)

Childhood Immunization and Public Health

edited by Carsten Krüger

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1187 | Submission Open

Keywords: compulsory/mandatory vaccination; coverage; local vaccination culture; pandemics; trust; vaccination frameworks; vaccine equity; vaccine hesitancy; zero-dose

(This special issue belongs to the Section Vaccines and Public Health)

Strategies for Addressing Vaccine Hesitancy

edited by

Donald J. Alcendor

submission deadline 31 Aug 2025 | Viewed by 658 | Submission Open

Keywords: vaccines; vaccine hesitancy; vaccine uptake; vaccine misinformation; vaccine disparities

(This special issue belongs to the Section Vaccines and Public Health)

The 2nd Edition: Non-Specific Protection in the Response to Vaccination and Other Immune Stimulation

edited by

François Meurens

Fanny Renois

and

Jianzhong Zhu

submission deadline 31 Aug 2025 | Viewed by 459 | Submission Open

Keywords: non-specific protections; vaccination; non-specific effects (NSEs); trained immunity; immune system; pathogens

(This special issue belongs to the Section Pathogens-Host Immune Boundaries)

Studies of Infectious Disease Epidemiology and Vaccination

edited by

Jose Gonzales-Zamora

and Shweta Anjan

submission deadline 31 Aug 2025 | Viewed by 389 | Submission Open

Keywords: vaccine effectiveness; vaccination policies; cost-effectiveness; surveillance; public health; high-risk population; infectious diseases

(This special issue belongs to the Section Epidemiology and Vaccination)

Vaccination Advances for HBV, HPV, and Influenza

edited by

Wangnan Cao

submission deadline 31 Aug 2025 | Viewed by 318 | Submission Open

Keywords: HBV; HPV; influenza; vaccination

(This special issue belongs to the Section Vaccines and Public Health)

The Need for an HIV Vaccine in the Era of Highly Effective PrEP

edited by Michele Peake Andrasik, William O. Hahn and Susan P. Buchbinder

submission deadline 31 Aug 2025 | Viewed by 287 | Submission Open

Keywords: HIV; vaccines; HIV prevention; bnAbs; clinical trials

(This special issue belongs to the Section HIV Vaccines)

Modulating CD4+ T Cells for Cancer Immunotherapy: Emerging Strategies and Applications

edited by

Haval Shirwan

submission deadline 1 Sep 2025 | 2 articles | Viewed by 4764 | Submission Open

Keywords: CD4+ T cells; immunomodulation; cancer immunotherapy; cancer vaccines; immunotherapeutic agents

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Virus Pandemics and Vaccinations

edited by Renata Gili,

Davide Gori

and

Matteo Riccò

submission deadline 1 Sep 2025 | 3 articles | Viewed by 3942 | Submission Open

Keywords: vaccine; vaccination strategy; one health; emerging pathogens; vaccine hesitancy

(This special issue belongs to the Section Vaccines and Public Health)

Swine Vaccines and Vaccination

edited by

Fanzhi Kong

submission deadline 1 Sep 2025 | 1 articles | Viewed by 964 | Submission Open

Keywords: swine fever; classical swine fever virus; african swine fever virus; live attenuated vaccines; subunit vaccines; nanopartical vaccines

(This special issue belongs to the Section Veterinary Vaccines)

Inequality in Immunization 2025

edited by

Ahmad Reza Hosseinpoor

and Ibrahim Dadari

submission deadline 15 Sep 2025 | 4 articles | Viewed by 3951 | Submission Open

Keywords: health inequalities; immunization; vaccine inequality; events affecting vaccinology; monitoring

(This special issue belongs to the Section Vaccines and Public Health)

Maternal and Infant Vaccines

edited by Prabha Andraweera and Bing Wang

submission deadline 20 Sep 2025 | Viewed by 150 | Submission Open

Keywords: maternal vaccines; infant vaccines; immunogenicity; effectiveness; vaccine uptake; safety

Vaccination Strategies for Global Public Health

edited by

Mathumalar Fahrni

and

Antonio Ivan Lazzarino

submission deadline 30 Sep 2025 | 15 articles | Viewed by 32875 | Submission Open

Keywords: emerging infectious disease; SARS-CoV-2; human monkeypox; dengue; henipavirus; public health; population-based studies; modelling; social impact; equitable access; vaccination

(This special issue belongs to the Section Vaccines and Public Health)

Varicella and Zoster Vaccination

edited by

Peter Maple

submission deadline 30 Sep 2025 | 14 articles | Viewed by 27193 | Submission Open

Keywords: varicella-zoster virus; chickenpox; shingles; vaccination; epidemiology; geographical regions; neurological diseases; SARS-CoV-2

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Peptide-Based Vaccines

edited by

Waleed Hussein

Mariusz Skwarczynski

and Ahmed O. Shalash

submission deadline 30 Sep 2025 | 4 articles | Viewed by 8742 | Submission Open

Keywords: peptide-based vaccines; infectious diseases; prophylactic vaccines; therapeutic vaccines; cancer; vaccine formulations; adjuvants

Role of Next Generation Vaccines in Immunotherapeutics

edited by Swayam Prakash

submission deadline 30 Sep 2025 | 4 articles | Viewed by 8078 | Submission Open

Keywords: immunotherapeutics; vaccines; nucleic acid vaccines; viral vector and protein subunit vaccines; cancer vaccines; autoimmune diseases and allergies; COVID-19; clinical trials; pre-clinical trials

The Current Development of Glycoconjugate Vaccines for Infectious Diseases

edited by Fatme Mawas

submission deadline 30 Sep 2025 | 4 articles | Viewed by 6147 | Submission Open

Keywords: bacterial vaccines; polysaccharides; conjugate vaccines; carrier proteins

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Hepatitis Vaccines: Safety, Efficacy and Global Impact

edited by

Muhammad Atif Zahoor

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3863 | Submission Open

Keywords: viral hepatitis; prevention of viral hepatitis through effective vaccines; safety and efficacy of hepatitis vaccines; immunogenicity of hepatitis vaccines; vaccine innovation; global prevention strategies; global health impact; vaccine failures and future challenges

(This special issue belongs to the Section Hepatitis Virus Vaccines)

Development of Vaccines Against Bacterial Infections

edited by

John Hwa Lee

and Amal Senevirathne

submission deadline 30 Sep 2025 | 3 articles | Viewed by 3856 | Submission Open

Keywords: novel vaccine formulations; bacterial pathogenesis mechanisms; immunogenicity assessment; vaccine efficacy studies; next-generation vaccine platforms; targeted antigen design; novel adjuvants; vaccine clinical trials; vaccine delivery systems; vaccine cross-protection

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

3rd Edition: Safety and Autoimmune Response to SARS-CoV-2 Vaccination

edited by

Minghui Yang

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1970 | Submission Open

Keywords: COVID-19 vaccine; vaccine efficacy; vaccine safety; adverse events following immunization

(This special issue belongs to the Section COVID-19 Vaccines and Vaccination)

Bioengineering Strategies for Developing Vaccines

edited by Chen Zhao and Jiayi Shu

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1310 | Submission Open

Keywords: vaccine platform; antigen design; targeted delivery; mRNA; nanoparticle; artificial intelligence

Vaccine Hesitancy and Acceptance

edited by Karl Hess, Jeff Goad and Laressa Bethishou

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1197 | Submission Open

Keywords: vaccine hesitancy; vaccine acceptance; barriers to vaccination; vaccination strategies

(This special issue belongs to the Section Vaccines and Public Health)

Oral and Nucleic Acid Vaccines for Zoonotic and Animal Infectious Diseases

edited by Lei Shuai

submission deadline 30 Sep 2025 | 1 articles | Viewed by 1034 | Submission Open

Keywords: oral vaccines; nucleic acid vaccines; zoonotic diseases; animal infectious diseases; vaccine development; vaccine safety; vaccine efficacy; immunological mechanism

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Hesitancy in the Era of COVID-19

edited by

and

submission deadline 30 Sep 2025 | Viewed by 536 | Submission Open

Keywords: vaccine hesitancy; evidence synthesis; COVID-19

(This special issue belongs to the Section Vaccines and Public Health)

Animal Vaccines: 2nd Edition

edited by

Hsian-Yu Wang

and

David Benfield

submission deadline 30 Sep 2025 | Viewed by 380 | Submission Open

Keywords: animal vaccines; novel antigen or adjuvant design; vaccine technologies

(This special issue belongs to the Section Veterinary Vaccines)

Vaccine Against Sexually Transmitted Diseases

edited by Weiming Tang

submission deadline 30 Sep 2025 | Viewed by 304 | Submission Open

Keywords: vaccination; sexually transmitted infections; HPV; HIV; syphilis; gonorrhea; and chlamydia; vaccine development; public health; epidemiology; health equity; preventive strategies

(This special issue belongs to the Section HIV Vaccines)

Innovations in Immunotherapy: Advancements in Cancer Vaccines and Immune Modulation

edited by

Nan Zhang

and

Hao Zhang

submission deadline 30 Sep 2025 | Viewed by 218 | Submission Open

Keywords: multi-omics; cancer therapy; precision medicine; cancer vaccines

(This special issue belongs to the Section Vaccination Against Cancer and Chronic Diseases)

Virus-Like Particle (VLP) Vaccines Against Emerging Infectious Diseases—2nd Edition

edited by

Gang Ye

submission deadline 30 Sep 2025 | Viewed by 175 | Submission Open

Keywords: emerging infectious diseases (EIDs); virus-like particle (VLP); vaccines

(This special issue belongs to the Section Vaccine Design, Development, and Delivery)

Factors Affecting Influenza Vaccine Uptake

edited by

Adriana Pistol

submission deadline 20 Oct 2025 | 1 articles | Viewed by 1573 | Submission Open

Keywords: influenza; vaccines; coverage; uptake; hesitancy; risk groups

(This special issue belongs to the Section Influenza Virus Vaccines)

New Technology for Vaccines and Vaccine-Preventable Diseases

edited by

Jue Liu

submission deadline 20 Oct 2025 | 2 articles | Viewed by 1055 | Submission Open

Keywords: artificial intelligence in vaccines; big data in vaccine research; emerging infectious diseases; vaccine accessibility; vaccine delivery systems; vaccine efficacy and safety; vaccine-preventable diseases; vaccine technology

(This special issue belongs to the Section Vaccines against Tropical and other Infectious Diseases)

Viral Vector-Based and Other Vaccine Strategies for Poultry and Livestock

edited by Mathias Martins

submission deadline 20 Oct 2025 | Viewed by 363 | Submission Open

Keywords: vaccine strategies; viral vector-based vaccines; poultry; livestock; infectious diseases; immune responses; vaccine platforms; genetic engineering; veterinary medicine; antigen delivery

(This special issue belongs to the Section Veterinary Vaccines)

Vaccines Against Influenza and Other Respiratory Virus Infections

edited by

Santosh Dhakal

submission deadline 20 Oct 2025 | Viewed by 179 | Submission Open

Keywords: adjuvants; influenza; mucosal immunity; respiratory viral pathogens; vaccine effectiveness; vaccine safety

(This special issue belongs to the Section Influenza Virus Vaccines)

Immunization Strategies for Animal Health

edited by Eva Calvo-Pinilla and

Alejandro Marin-Lopez

submission deadline 31 Oct 2025 | 6 articles | Viewed by 16846 | Submission Open

Keywords: vaccine immunology; virus; emerging infectious disease; animal health; public health; vaccination

(This special issue belongs to the Section Veterinary Vaccines)

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