Polymers, Volume 15, Issue 13
2023 July-1 - 220 articles
Cover Story: This work reports the construction of a bicomponent scaffold co-loaded with both prodrug and drug as an efficient platform for wound dressing, by combining electrospinning and 3D-printing technologies. The outer component consisted of a chitosan/polyethylene oxide-electrospun membrane loaded with indomethacin–polyethylene glycol–indomethacin prodrug and served as a support for printing the inner component, a gelatin methacryloyl/sodium alginate hydrogel loaded with tetracycline hydrochloride. The bicomponent scaffold showed good biocompatibility on HeLa cells, excellent antimicrobial activity against E. coli and S. aureus bacteria, and promising anti-inflammatory and proangiogenic activities, proving its potential to be used for wound dressing. View this paper - Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
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