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Nutrients, Volume 9, Issue 5

2017 May - 107 articles

Cover Story: The Mediterranean diet has been proven to be highly effective in the prevention of cardiovascular diseases and cancer and in decreasing overall mortality. Nowadays, transcriptomics is gaining particular relevance due to the existence of non-coding RNAs capable of regulating many biological processes. The present work describes a systematic review of current evidence supporting the influence of the Mediterranean diet on transcriptomes of different tissues in various experimental models. View this paper
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Articles (107)

  • Article
  • Open Access
10 Citations
6,322 Views
10 Pages

10 May 2017

Objective: To examine the association of serum 25-hydroxyvitamin D [25(OH)D] concentrations with critical and severe hand, foot and mouth disease (HFMD) and assess the clinical significance and prognostic effect of 25(OH)D concentrations in children...

  • Article
  • Open Access
25 Citations
5,065 Views
9 Pages

10 May 2017

It has been demonstrated that low bone mass and vitamin D deficiency occur in adult patients receiving home parenteral nutrition (HPN). The aim of this study is to determine the prevalence of vitamin D insufficiency and deficiency and its relationshi...

  • Article
  • Open Access
6 Citations
7,299 Views
10 Pages

Color-Coded Front-of-Pack Nutrition Labels—An Option for US Packaged Foods?

  • Elizabeth K. Dunford,
  • Jennifer M. Poti,
  • Dagan Xavier,
  • Jacqui L. Webster and
  • Lindsey Smith Taillie

10 May 2017

The implementation of a standardized front-of-pack-labelling (FoPL) scheme would likely be a useful tool for many consumers trying to improve the healthfulness of their diets. Our objective was to examine what the traffic light labelling scheme would...

  • Article
  • Open Access
11 Citations
4,924 Views
16 Pages

Multibehavioural Interventions with a Focus on Specific Energy Balance-Related Behaviours Can Affect Diet Quality in Preschoolers from Six European Countries: The ToyBox-Study

  • An-Sofie Pinket,
  • Marieke De Craemer,
  • Inge Huybrechts,
  • Ilse De Bourdeaudhuij,
  • Benedicte Deforche,
  • Greet Cardon,
  • Odysseas Androutsos,
  • Berthold Koletzko,
  • Luis A. Moreno and
  • Wendy Van Lippevelde
  • + 3 authors

10 May 2017

The present study aimed to examine whether a multibehavioural intervention with a focus on specific energy balance-related behaviours can affect total diet quality and its four subcomponents in European preschoolers and to investigate if these interv...

  • Article
  • Open Access
12 Citations
6,536 Views
19 Pages

An In Vivo Magnetic Resonance Spectroscopy Study of the Effects of Caloric and Non-Caloric Sweeteners on Liver Lipid Metabolism in Rats

  • Sharon Janssens,
  • Jolita Ciapaite,
  • Justina C. Wolters,
  • Natal A. Van Riel,
  • Klaas Nicolay and
  • Jeanine J. Prompers

10 May 2017

We aimed to elucidate the effects of caloric and non-caloric sweeteners on liver lipid metabolism in rats using in vivo magnetic resonance spectroscopy (MRS) and to determine their roles in the development of liver steatosis. Wistar rats received nor...

  • Article
  • Open Access
222 Citations
15,846 Views
21 Pages

The Neuroprotective Effects of Phenolic Acids: Molecular Mechanism of Action

  • Dominik Szwajgier,
  • Kamila Borowiec and
  • Katarzyna Pustelniak

10 May 2017

The neuroprotective role of phenolic acids from food has previously been reported by many authors. In this review, the role of phenolic acids in ameliorating depression, ischemia/reperfusion injury, neuroinflammation, apoptosis, glutamate-induced tox...

  • Article
  • Open Access
15 Citations
9,630 Views
9 Pages

The Impact of Diet Wheat Source on the Onset of Type 1 Diabetes Mellitus—Lessons Learned from the Non-Obese Diabetic (NOD) Mouse Model

  • Jonathan Gorelick,
  • Ludmila Yarmolinsky,
  • Arie Budovsky,
  • Boris Khalfin,
  • Joshua D. Klein,
  • Yosi Pinchasov,
  • Maxim A. Bushuev,
  • Tatiana Rudchenko and
  • Shimon Ben-Shabat

10 May 2017

Nutrition, especially wheat consumption, is a major factor involved in the onset of type 1 diabetes (T1D) and other autoimmune diseases such as celiac. While modern wheat cultivars possess similar gliadin proteins associated with the onset of celiac...

  • Review
  • Open Access
47 Citations
10,070 Views
17 Pages

Transcriptomics and the Mediterranean Diet: A Systematic Review

  • Luis V. Herrera-Marcos,
  • José M. Lou-Bonafonte,
  • Carmen Arnal,
  • María A. Navarro and
  • Jesús Osada

9 May 2017

The Mediterranean diet has been proven to be highly effective in the prevention of cardiovascular diseases and cancer and in decreasing overall mortality. Nowadays, transcriptomics is gaining particular relevance due to the existence of non-coding RN...

  • Article
  • Open Access
32 Citations
9,941 Views
13 Pages

9 May 2017

Low glycaemic index (GI) foods minimize large blood glucose fluctuations and have been advocated to enhance fat oxidation and may contribute to weight management. We determined whether the inclusion of isomaltulose compared to sucrose in a low/high G...

  • Article
  • Open Access
83 Citations
15,667 Views
17 Pages

8 May 2017

Dietary Reference Values (DRVs) for vitamin D have a key role in the prevention of vitamin D deficiency. However, despite adopting similar risk assessment protocols, estimates from authoritative agencies over the last 6 years have been diverse. This...

  • Article
  • Open Access
26 Citations
11,196 Views
13 Pages

Psychometric Properties of a Developed Questionnaire to Assess Knowledge, Attitude and Practice Regarding Vitamin D (D-KAP-38)

  • Parisa Amiri,
  • Golaleh Asghari,
  • Hoda Sadrosadat,
  • Mehrdad Karimi,
  • Atieh Amouzegar,
  • Parvin Mirmiran and
  • Fereidoun Azizi

8 May 2017

The aim of this study was to develop a valid and reliable questionnaire to assess vitamin D-related knowledge, attitude and practices in Tehranian adults, who may be at increased risk of vitamin D deficiency. This study was conducted on 572 individua...

  • Review
  • Open Access
91 Citations
19,031 Views
14 Pages

Parenteral Nutrition and Intestinal Failure

  • Barbara Bielawska and
  • Johane P. Allard

6 May 2017

Severe short bowel syndrome (SBS) is a major cause of chronic (Type 3) intestinal failure (IF) where structural and functional changes contribute to malabsorption and risk of micronutrient deficiencies. Chronic IF may be reversible, depending on anat...

  • Article
  • Open Access
21 Citations
8,262 Views
13 Pages

The Effect of Isomaltulose Together with Green Tea on Glycemic Response and Antioxidant Capacity: A Single-Blind, Crossover Study in Healthy Subjects

  • Passakorn Suraphad,
  • Phim On Suklaew,
  • Sathaporn Ngamukote,
  • Sirichai Adisakwattana and
  • Kittana Mäkynen

6 May 2017

Isomaltulose, a naturally-occurring isomer of sucrose, is commonly used as an alternative sweetener in foods and beverages. The goal of this study was to determine the effect of isomaltulose together with green tea on postprandial plasma glucose and...

  • Article
  • Open Access
9 Citations
7,115 Views
14 Pages

6 May 2017

Inflammatory bowel disease (IBD) is induced by multiple environmental factors, and there is still no known treatment capable of curing the disease completely. We propose a zeolite-containing mixture (Hydryeast®, HY)—a multi-component nutraceutical of...

  • Article
  • Open Access
30 Citations
13,638 Views
15 Pages

6 May 2017

Picky eating behaviors are frequently observed in childhood, leading to concern that an unbalanced and inadequate diet will result in unfavorable growth outcomes. However, the association between picky eating behaviors and nutritional status has not...

  • Review
  • Open Access
112 Citations
34,565 Views
22 Pages

6 May 2017

Metabolic adaptations occur with weight loss that result in increased hunger with discordant simultaneous reductions in energy requirements—producing the so-called energy gap in which more energy is desired than is required. The increased hunger is a...

  • Article
  • Open Access
73 Citations
8,862 Views
14 Pages

6 May 2017

Zinc (Zn) deficiency is a common disorder of humans in developing countries. The effect of Zn biofortification (via application of six rates of Zn fertilizer to soil) on Zn bioavailability in wheat grain and flour and its impacts on human health was...

  • Article
  • Open Access
8 Citations
6,639 Views
12 Pages

An Innovative Method for Monitoring Food Quality and the Healthfulness of Consumers’ Grocery Purchases

  • Le-Thuy T. Tran,
  • Philip J. Brewster,
  • Valliammai Chidambaram and
  • John F. Hurdle

5 May 2017

This study presents a method laying the groundwork for systematically monitoring food quality and the healthfulness of consumers’ point-of-sale grocery purchases. The method automates the process of identifying United States Department of Agriculture...

  • Article
  • Open Access
40 Citations
10,365 Views
14 Pages

Iodine Status and Iodised Salt Consumption in Portuguese School-Aged Children: The Iogeneration Study

  • João Costa Leite,
  • Elisa Keating,
  • Diogo Pestana,
  • Virgínia Cruz Fernandes,
  • Maria Luz Maia,
  • Sónia Norberto,
  • Edgar Pinto,
  • André Moreira-Rosário,
  • Diana Sintra and
  • Conceição Calhau
  • + 19 authors

5 May 2017

The World Health Organization promotes salt iodisation to control iodine deficiency. In Portugal, the use of iodised salt in school canteens has been mandatory since 2013. The present study aimed to evaluate iodine status in school-aged children (6–1...

  • Article
  • Open Access
25 Citations
6,019 Views
14 Pages

Acute Vitamin D3 Supplementation in Severe Obesity: Evaluation of Multimeric Adiponectin

  • Stefania Mai,
  • Gillian E. Walker,
  • Roberta Vietti,
  • Stefania Cattaldo,
  • Chiara Mele,
  • Lorenzo Priano,
  • Alessandro Mauro,
  • Gianni Bona,
  • Gianluca Aimaretti and
  • Paolo Marzullo
  • + 1 author

5 May 2017

Obesity predisposes to vitamin D deficiency (VDD) and glucose abnormalities. It is currently debated if vitamin D administration may improve glucose homeostasis by interacting with modulators of insulin sensitivity, such as adiponectin and its oligom...

  • Article
  • Open Access
14 Citations
6,910 Views
13 Pages

5 May 2017

Immigrants in the U.S. may encounter challenges of acculturation, including dietary habits, as they adapt to new surroundings. We examined Vietnamese and Hispanic immigrant children’s American food consumption patterns in a convenience sample of 63 V...

  • Review
  • Open Access
116 Citations
17,951 Views
13 Pages

Effect of Probiotics on Metabolic Outcomes in Pregnant Women with Gestational Diabetes: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

  • Bonnie L. Taylor,
  • Georgia E. Woodfall,
  • Katherine E. Sheedy,
  • Meggan L. O’Riley,
  • Kelsie A. Rainbow,
  • Elsa L. Bramwell and
  • Nicole J. Kellow

5 May 2017

The metabolic effects of probiotic administration in women with gestational diabetes mellitus (GDM) is unknown. The objective of this review was to investigate the effect of probiotics on fasting plasma glucose (FPG), insulin resistance (HOMA-IR) and...

  • Article
  • Open Access
15 Citations
6,382 Views
15 Pages

5 May 2017

Studies on one-carbon metabolism for the assessment of folate deficiency have focused on either metabolites of folate metabolism or methionine cycle. To bridge the gap between deficiency markers in these pathways we designed a dietary induced folate...

  • Article
  • Open Access
293 Citations
31,533 Views
17 Pages

4 May 2017

Polyphenols are plant secondary metabolites containing antioxidant properties, which help to protect chronic diseases from free radical damage. Dietary polyphenols are the subject of enhancing scientific interest due to their possible beneficial effe...

  • Article
  • Open Access
7 Citations
6,156 Views
8 Pages

4 May 2017

To reduce weight gain and encourage healthy eating including reduced sugar intake, Under 5 Energize (U5E) was introduced to 121 early-childhood-centres in the Waikato region of New Zealand in July 2013. Using anonymized data collected from January 20...

  • Article
  • Open Access
27 Citations
7,830 Views
12 Pages

The Effect of a Mediterranean Diet on the Incidence of Cataract Surgery

  • Alfredo García-Layana,
  • Gianfranco Ciufo,
  • Estefania Toledo,
  • Miguel A. Martínez-González,
  • Dolores Corella,
  • Montse Fitó,
  • Ramon Estruch,
  • Enrique Gómez-Gracia,
  • Miguel Fiol and
  • Fernando Arós
  • + 10 authors

3 May 2017

Background: Cataract is a leading cause of vision impairment worldwide, and surgery is the only available treatment. The process that initiates lens opacification is dependent on the oxidative stress experienced by the lens components. A healthy over...

  • Article
  • Open Access
66 Citations
12,672 Views
19 Pages

Polyphenol Levels Are Inversely Correlated with Body Weight and Obesity in an Elderly Population after 5 Years of Follow Up (The Randomised PREDIMED Study)

  • Xiaohui Guo,
  • Anna Tresserra-Rimbau,
  • Ramón Estruch,
  • Miguel A. Martínez-González,
  • Alexander Medina-Remón,
  • Montserrat Fitó,
  • Dolores Corella,
  • Jordi Salas-Salvadó,
  • Maria Puy Portillo and
  • Rosa M. Lamuela-Raventós
  • + 2 authors

3 May 2017

Overweight and obesity have been steadily increasing in recent years and currently represent a serious threat to public health. Few human studies have investigated the relationship between polyphenol intake and body weight. Our aim was to assess the...

  • Article
  • Open Access
27 Citations
10,204 Views
15 Pages

3 May 2017

Dietary strategies to reduce discretionary choice intake are commonly utilized in practice, but evidence on their relative efficacy is lacking. The aim was to compare the potential impact on nutritional intake of three strategies to reducing discreti...

  • Article
  • Open Access
17 Citations
6,558 Views
12 Pages

Development of a Healthy Dietary Habits Index for New Zealand Adults

  • Jyh Eiin Wong,
  • Jillian J. Haszard,
  • Anna S. Howe,
  • Winsome R. Parnell and
  • Paula M. L. Skidmore

3 May 2017

Healthful dietary habits are individually associated with better nutrient intake and positive health outcomes; however, this information is rarely examined together to validate an indicator of diet quality. This study developed a 15-item Healthy Diet...

  • Article
  • Open Access
37 Citations
9,035 Views
9 Pages

Evaluation of the Efficiency of the Reticulocyte Hemoglobin Content on Diagnosis for Iron Deficiency Anemia in Chinese Adults

  • Jie Cai,
  • Meng Wu,
  • Jie Ren,
  • Yali Du,
  • Zhangbiao Long,
  • Guoxun Li,
  • Bing Han and
  • Lichen Yang

2 May 2017

Our aim was to evaluate the cut-off value and efficiency of using reticulocyte hemoglobin content as a marker to diagnose iron deficiency anemia in Chinese adults. 140 adults who needed bone marrow aspiration for diagnosis at the hematology departmen...

  • Article
  • Open Access
11 Citations
6,462 Views
13 Pages

Dietary BCAA Intake Is Associated with Demographic, Socioeconomic and Lifestyle Factors in Residents of São Paulo, Brazil

  • Ana Carolina Pallottini,
  • Cristiane Hermes Sales,
  • Diva Aliete dos Santos Vieira,
  • Dirce Maria Marchioni and
  • Regina Mara Fisberg

2 May 2017

Background: Identifying which risk groups have a higher intake of branched chain amino acids (BCAA) is important for the planning of public policies. This study was undertaken to investigate BCAA consumption, the foods contributing to that consumptio...

  • Article
  • Open Access
49 Citations
7,421 Views
17 Pages

2 May 2017

Parkinson’s disease (PD) is an age-related neurological disorder characterized by a loss of dopaminergic neurons within the midbrain. Neuroinflammation has been nominated as one of the key pathogenic features of PD. Recently, the inadequate pharmacot...

  • Review
  • Open Access
108 Citations
10,636 Views
14 Pages

The Impact of Exclusive Enteral Nutrition (EEN) on the Gut Microbiome in Crohn’s Disease: A Review

  • Amber MacLellan,
  • Jessica Connors,
  • Shannan Grant,
  • Leah Cahill,
  • Morgan G. I. Langille and
  • Johan Van Limbergen

1 May 2017

Crohn’s disease (CD), a form of inflammatory bowel disease (IBD), is thought to arise from a complex interaction of genetics, the gut microbiome, and environmental factors, such as diet. There is clear evidence that dietary intervention is successful...

  • Article
  • Open Access
9 Citations
4,863 Views
9 Pages

Association between Alcohol Consumption, Folate Intake, and Risk of Pancreatic Cancer: A Case-Control Study

  • Winta Yallew,
  • William R. Bamlet,
  • Ann L. Oberg,
  • Kristin E. Anderson,
  • Janet E. Olson,
  • Rashmi Sinha,
  • Gloria M. Petersen,
  • Rachael Z. Stolzenberg-Solomon and
  • Rick J. Jansen

1 May 2017

Pancreatic cancer is one of the most fatal common cancers affecting both men and women, representing about 3% of all new cancer cases in the United States. In this study, we aimed to investigate the association of pancreatic cancer risk with alcohol...

  • Article
  • Open Access
61 Citations
10,745 Views
15 Pages

Non-Traditional Aspects of Renal Diets: Focus on Fiber, Alkali and Vitamin K1 Intake

  • Adamasco Cupisti,
  • Claudia D'Alessandro,
  • Loreto Gesualdo,
  • Carmela Cosola,
  • Maurizio Gallieni,
  • Maria Francesca Egidi and
  • Maria Fusaro

29 April 2017

Renal diets for advanced chronic kidney disease (CKD) are structured to achieve a lower protein, phosphate and sodium intake, while supplying adequate energy. The aim of this nutritional intervention is to prevent or correct signs, symptoms and compl...

  • Article
  • Open Access
46 Citations
9,701 Views
20 Pages

Improvement of Antioxidant Defences and Mood Status by Oral GABA Tea Administration in a Mouse Model of Post-Stroke Depression

  • Maria Daglia,
  • Arianna Di Lorenzo,
  • Seyed Fazel Nabavi,
  • Antoni Sureda,
  • Sedigheh Khanjani,
  • Akbar Hajizadeh Moghaddam,
  • Nady Braidy and
  • Seyed Mohammad Nabavi

29 April 2017

Green GABA (GGABA) and Oolong GABA (OGABA) teas are relatively new varieties of tea, whose chemical composition and functional properties are largely under-studied, despite their promising health capacities. Post stroke depression (PSD) is a complica...

  • Article
  • Open Access
41 Citations
13,311 Views
12 Pages

29 April 2017

Good knowledge of nutrition is widely thought to be an important aspect to maintaining a balanced and healthy diet. The aim of this study was to develop and validate a new reliable tool to measure the general and the sport nutrition knowledge (GeSNK)...

  • Review
  • Open Access
181 Citations
15,235 Views
9 Pages

The “Metabolic Memory” Theory and the Early Treatment of Hyperglycemia in Prevention of Diabetic Complications

  • Roberto Testa,
  • Anna Rita Bonfigli,
  • Francesco Prattichizzo,
  • Lucia La Sala,
  • Valeria De Nigris and
  • Antonio Ceriello

28 April 2017

Several epidemiological and prospective studies suggest that an early intensive control of hyperglycaemia is able to decrease the risk of diabetic micro- and macro-vascular complications. A growing body of experimental evidence supports the concept t...

  • Concept Paper
  • Open Access
8 Citations
17,231 Views
14 Pages

28 April 2017

Providing nutritional education for chronic kidney disease (CKD) patients in South Africa is complicated by several conditions: the population is composed of diverse ethnic groups, each with its own culture and food preferences; eleven languages are...

  • Article
  • Open Access
52 Citations
8,093 Views
14 Pages

28 April 2017

Osteoclasts are large, multinucleated cells that are responsible for the breakdown or resorption of bone during bone remodelling. Studies have shown that certain fatty acids (FAs) can increase bone formation, reduce bone loss, and influence total bon...

  • Article
  • Open Access
72 Citations
10,132 Views
13 Pages

28 April 2017

Pomegranate (Punica granatum L.), a nutrient-rich unique fruit, has been used for centuries for the prevention and treatment of various inflammation-driven diseases. Based on our previous study, a characterized pomegranate emulsion (PE) exhibited a s...

  • Article
  • Open Access
42 Citations
11,963 Views
15 Pages

28 April 2017

The present randomized controlled study aimed to investigate the in vivo distribution of constituents or metabolites of the standardized maritime pine bark extract Pycnogenol®. Thirty-three patients with severe osteoarthritis scheduled for a knee art...

  • Article
  • Open Access
71 Citations
7,507 Views
13 Pages

Relationship of the Reported Intakes of Fat and Fatty Acids to Body Weight in US Adults

  • Susan K Raatz,
  • Zach Conrad,
  • LuAnn K Johnson,
  • Matthew J Picklo and
  • Lisa Jahns

28 April 2017

Dietary fat composition may modulate energy expenditure and body weight. Little is known about the relationship between fatty acid intake and body weight at a population level. The purposes of this study were to compare intakes of energy, macronutrie...

  • Review
  • Open Access
67 Citations
14,964 Views
11 Pages

Trace Elements in Parenteral Nutrition: Considerations for the Prescribing Clinician

  • Jennifer Jin,
  • Leanne Mulesa and
  • Mariana Carrilero Rouillet

28 April 2017

Trace elements (TEs) are an essential component of parenteral nutrition (PN). Over the last few decades, there has been increased experience with PN, and with this knowledge more information about the management of trace elements has become available...

  • Article
  • Open Access
69 Citations
7,408 Views
9 Pages

Factors Associated with Decreased Lean Tissue Index in Patients with Chronic Kidney Disease

  • Yi-Wen Wang,
  • Ting-Yun Lin,
  • Ching-Hsiu Peng,
  • Jui-Lin Huang and
  • Szu-Chun Hung

27 April 2017

Muscle wasting is common and is associated with increased morbidity and mortality in patients with chronic kidney disease (CKD). However, factors associated with decreased muscle mass in CKD patients are seldom reported. We performed a cross-sectiona...

  • Article
  • Open Access
14 Citations
8,375 Views
15 Pages

27 April 2017

Although numerous studies have approached the effects of exposure to a Western diet (WD) on academic outcomes, very few have focused on foods consumed during snack times. We explored whether there is a link between nutritious snacking habits and acad...

  • Article
  • Open Access
51 Citations
10,365 Views
11 Pages

Effects of Vitamin D Supplementation on Bone Turnover Markers: A Randomized Controlled Trial

  • Verena Schwetz,
  • Christian Trummer,
  • Marlene Pandis,
  • Martin R. Grübler,
  • Nicolas Verheyen,
  • Martin Gaksch,
  • Armin Zittermann,
  • Winfried März,
  • Felix Aberer and
  • Stefan Pilz
  • + 6 authors

27 April 2017

Bone turnover markers (BTMs) are used to evaluate bone health together with bone mineral density and fracture assessment. Vitamin D supplementation is widely used to prevent and treat musculoskeletal diseases but existing data on vitamin D effects on...

  • Article
  • Open Access
42 Citations
6,172 Views
15 Pages

26 April 2017

This study was conducted to explore whether exposure to bisphenol A (BPA) during pregnancy could change intestinal digestion and absorption function in offspring using pigs as a model, and whether methyl donor (MET) could counteract the BPA-induced i...

  • Review
  • Open Access
49 Citations
20,635 Views
19 Pages

Fructose, Glucocorticoids and Adipose Tissue: Implications for the Metabolic Syndrome

  • Balázs Legeza,
  • Paola Marcolongo,
  • Alessandra Gamberucci,
  • Viola Varga,
  • Gábor Bánhegyi,
  • Angiolo Benedetti and
  • Alex Odermatt

26 April 2017

The modern Western society lifestyle is characterized by a hyperenergetic, high sugar containing food intake. Sugar intake increased dramatically during the last few decades, due to the excessive consumption of high-sugar drinks and high-fructose cor...

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Nutrients - ISSN 2072-6643