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457 Results Found

  • Article
  • Open Access
58 Citations
8,951 Views
17 Pages

24 July 2020

Although self-esteem has traditionally been considered as an important correlate of psychosocial adjustment, some empirical studies have found a positive relationship between some domains of self-esteem and drug use among adolescents. The present stu...

  • Article
  • Open Access
1 Citations
1,301 Views
19 Pages

The “What” of Athletes’ Goal Pursuit and Its Relationships to Goal-Related Processes and Well- and Ill-Being

  • Natalia Martínez-González,
  • Francisco L. Atienza,
  • Joan L. Duda and
  • Isabel Balaguer

12 May 2025

Goal Contents Theory (GCT) postulates that the goals people pursue not only direct their perceptions of and behaviors relevant to goal pursuit, but also hold implications for their well- and ill-being. Extending past sport work grounded in this theor...

  • Article
  • Open Access
26 Citations
14,336 Views
15 Pages

The Institute of Medicine recently proposed a new case definition for chronic fatigue syndrome (CFS), as well as a new name, Systemic Exertion Intolerance Disease (SEID). Contrary to the Fukuda et al.’s CFS case definition, there are few exclusionary...

  • Article
  • Open Access
1,622 Views
12 Pages

31 July 2024

Background: Previous research has emphasized the significant role of illness perception in chronic diseases, including Multiple Sclerosis. Limited research has been conducted on exploring illness perception in Pediatric Onset Multiple Sclerosis (POMS...

  • Brief Report
  • Open Access
6 Citations
2,933 Views
9 Pages

The Mental Well-Being of Italian Adolescents in the Last Decade through the Lens of the Dual Factor Model

  • Michela Bersia,
  • Lorena Charrier,
  • Paola Berchialla,
  • Alina Cosma,
  • Rosanna Irene Comoretto and
  • Paola Dalmasso

16 December 2022

(1) Background: In Italy, the components of adolescents’ mental well-being (psychological symptomatology and cognitive perception of life satisfaction) showed different temporal trends, suggesting the adoption of a multidimensional conceptualiz...

  • Article
  • Open Access
1 Citations
1,997 Views
12 Pages

Blood-Biomarkers for Glucose Metabolism in Preterm Infants

  • Mia O. Bjerager,
  • Bo M. Hansen,
  • Frederik Sørensen,
  • Jes R. Petersen,
  • Kristian V. Jensen,
  • Brian R. Hjelvang,
  • Anna C. Hvelplund,
  • Dorte A. Olsen,
  • Aneta A. Nielsen and
  • Carina Slidsborg
  • + 3 authors

This was an exploratory, prospective, longitudinal, cohort study that aimed to establish “healthy” reference levels related to growth parameters and glucose metabolites in preterm infants. This was conducted to further investigate growth...

  • Article
  • Open Access
15 Citations
6,799 Views
15 Pages

Perfectionism is considered to be an important personality factor within the dance context given the high number of dancers whose psychological health is influenced by its consequences. The relationship between perfectionism and dancers’ well-...

  • Article
  • Open Access
880 Views
13 Pages

19 September 2025

Background and Objectives: Hematological diseases can cause lasting physical and social impairments. Illness perception and emotional functioning, influenced by stigmatization and optimism, may shape these outcomes, yet their combined effects on heal...

  • Article
  • Open Access
12 Citations
4,045 Views
13 Pages

Factors Determining the Level of Acceptance of Illness and Satisfaction with Life in Patients with Cancer

  • Renata Piotrkowska,
  • Agnieszka Kruk,
  • Aneta Krzemińska,
  • Wioletta Mędrzycka-Dąbrowska and
  • Katarzyna Kwiecień-Jaguś

Introduction: Cancer threatens life and brings about many negative emotions in patients, which influence their satisfaction with life and contribute to a low level of their acceptance of illness. This is why the acceptance of illness is a serious pro...

  • Review
  • Open Access
30 Citations
5,235 Views
20 Pages

22 November 2022

Objective: Dose optimization of novel β-lactam antibiotics (NBLA) has become necessary given the increased prevalence of multidrug-resistant infections in intensive care units coupled with the limited number of available treatment options. Unfor...

  • Article
  • Open Access
19 Citations
4,391 Views
15 Pages

The dual-continua model of mental health distinguishes between mental illness (presence of mental disorders, such as depression) and mental well-being (presence of positive traits and abilities). This model also distinguishes between hedonic well-bei...

  • Article
  • Open Access
46 Citations
7,430 Views
15 Pages

Impact of Job Insecurity on Psychological Well- and Ill-Being among High Performance Coaches

  • Marte Bentzen,
  • Göran Kenttä,
  • Anne Richter and
  • Pierre-Nicolas Lemyre

Background: The evaluative nature of high performance (HP) sport fosters performance expectations that can be associated with harsh scrutiny, criticism, and job insecurity. In this context, (HP) sport is described as a highly competitive, complex, an...

  • Article
  • Open Access
1 Citations
2,829 Views
17 Pages

Oral Drug Absorption and Drug Disposition in Critically Ill Cardiac Patients

  • Lars-Olav Harnisch,
  • Jürgen Brockmöller,
  • Anne Hapke,
  • Juliane Sindern,
  • Ellen Bruns,
  • Ruben Evertz,
  • Karl Toischer,
  • Bernhard C. Danner,
  • Dorothee Mielke and
  • Tammam Abboud
  • + 1 author

(1) Background: In critically ill cardiac patients, parenteral and enteral food and drug administration routes may be used. However, it is not well known how drug absorption and metabolism are altered in this group of adult patients. Here, we analyze...

  • Article
  • Open Access
43 Citations
11,147 Views
23 Pages

Heat Alert and Response Systems (HARS) are currently undergoing testing and implementation in Canada. These programs seek to reduce the adverse health effects of heat waves on human health by issuing weather forecasts and warnings, informing individu...

  • Article
  • Open Access
919 Views
12 Pages

Background: Many workers in non-health settings interact with people with living experiences of mental ill-health but have little knowledge about the symptoms, the mental health system, or may hold stigmatising views. Aims: This study evaluated the i...

  • Article
  • Open Access
7 Citations
4,408 Views
13 Pages

Decreased CTRP3 Plasma Concentrations Are Associated with Sepsis and Predict Mortality in Critically Ill Patients

  • Eray Yagmur,
  • Simone Otto,
  • Ger H. Koek,
  • Ralf Weiskirchen,
  • Christian Trautwein,
  • Alexander Koch and
  • Frank Tacke

C1q/ tumor necrosis factor (TNF)-like protein 3 (CTRP3) represents a novel member of the adipokine family that exerts favorable metabolic actions in humans. However, the role of CTRP3 in critical illness and sepsis is currently unknown. Upon admissio...

  • Review
  • Open Access
23 Citations
9,310 Views
24 Pages

Therapeutic Drug Monitoring of Antifungal Agents in Critically Ill Patients: Is There a Need for Dose Optimisation?

  • Daniela Baracaldo-Santamaría,
  • Juan David Cala-Garcia,
  • Germán José Medina-Rincón,
  • Luis Carlos Rojas-Rodriguez and
  • Carlos-Alberto Calderon-Ospina

Invasive fungal infections are an important cause of morbidity and mortality, especially in critically ill patients. Increasing resistance rates and inadequate antifungal exposure have been documented in these patients, due to clinically relevant pha...

  • Article
  • Open Access
1 Citations
3,433 Views
9 Pages

15 January 2024

Type 2 diabetes mellitus (T2DM) affects a patient’s physical, social, and mental well-being. Perceptions of the illness are linked to quality of life. The aim of this study was to assess illness perception in patients diagnosed with T2DM and to...

  • Review
  • Open Access
6 Citations
8,785 Views
17 Pages

16 October 2020

Sleep disturbances accompany almost all mental illnesses, either because sound sleep and mental well-being share similar requisites, or because mental problems lead to sleep problems, or vice versa. The aim of this narrative review was to examine sle...

  • Article
  • Open Access
50 Citations
13,400 Views
12 Pages

Family Functioning and Psychological Health of Children with Mentally Ill Parents

  • Silke Wiegand-Grefe,
  • Marlit Sell,
  • Bonnie Filter and
  • Angela Plass-Christl

Parental mental illness can be linked to reduced family functioning, which is associated with more conflicts, less adaptability and cohesion as well as a disorganized pattern of everyday planning. Concurrently, family functioning is an important mode...

  • Article
  • Open Access
13 Citations
5,499 Views
12 Pages

Parent Attributions of Ambiguous Symptoms in Their Children: A Preliminary Measure Validation in Parents of Children with Chronic Pain

  • Lauren C. Heathcote,
  • Sara E. Williams,
  • Allison M. Smith,
  • Christine B. Sieberg and
  • Laura E. Simons

How parents attribute cause to their child’s physical symptoms is likely important in understanding how the parent responds to the child, as well as the child’s health outcomes, especially within the context of chronic illness. Here, we a...

  • Article
  • Open Access
861 Views
13 Pages

Background/Objectives: Increasing evidence has shown that terminal cancer patients experience a poor quality of life (QoL), but the complex internal structure of the QoL among terminal cancer patients is not well documented. This study aimed to explo...

  • Article
  • Open Access
10 Citations
3,316 Views
22 Pages

Evolution of External Health Costs of Electricity Generation in the Baltic States

  • Jintao Lu,
  • Chong Zhang,
  • Licheng Ren,
  • Mengshang Liang,
  • Wadim Strielkowski and
  • Justas Streimikis

Implementation of strict policies for mitigating climate change has a direct impact on public health as far as the external health costs of electricity generation can be reduced, thanks to the reduction of emission of typical pollutants by switching...

  • Feature Paper
  • Review
  • Open Access
13 Citations
3,302 Views
14 Pages

Mental Illness and Amyloid: A Scoping Review of Scientific Evidence over the Last 10 Years (2011 to 2021)

  • Gianluca Pandolfo,
  • Fiammetta Iannuzzo,
  • Giovanni Genovese,
  • Antonio Bruno,
  • Giovanni Pioggia,
  • Sergio Baldari and
  • Sebastiano Gangemi

14 October 2021

Amyloid precursor protein and its derivates represent a central factor in the process of neurodegeneration in Alzheimer’s disease (AD). Since mental illnesses share with AD cognitive impairment, amyloid indicators have been used to explore the unknow...

  • Review
  • Open Access
3 Citations
3,150 Views
19 Pages

15 March 2024

Forensic hospitals throughout the country house individuals with severe mental illness and history of criminal violations. Insomnia affects 67.4% of hospitalized patients with chronic neuropsychiatric disorders, indicating that these conditions may h...

  • Article
  • Open Access
42 Citations
10,600 Views
16 Pages

Children of Parents with a Mental Illness: Predictors of Health-Related Quality of Life and Determinants of Child–Parent Agreement

  • Alina Radicke,
  • Claus Barkmann,
  • Bonnie Adema,
  • Anne Daubmann,
  • Karl Wegscheider and
  • Silke Wiegand-Grefe

(1) Background: Health-related quality of life (HRQoL) is frequently reduced in children of parents with a mental illness (COPMI). Child self- and parent proxy-ratings vary with raters’ characteristics and facets of HRQoL. This study aimed at a...

  • Article
  • Open Access
22 Citations
3,586 Views
13 Pages

Immunosuppression as a Hallmark of Critical COVID-19: Prospective Study

  • Elżbieta Kalicińska,
  • Donata Szymczak,
  • Aleksander Zińczuk,
  • Barbara Adamik,
  • Jakub Smiechowicz,
  • Tomasz Skalec,
  • Danuta Nowicka-Suszko,
  • Monika Biernat,
  • Aleksandra Bogucka-Fedorczuk and
  • Tomasz Wróbel
  • + 4 authors

23 May 2021

The dysregulation of both the innate and adaptive responses to SARS-CoV-2 have an impact on the course of COVID-19, and play a role in the clinical outcome of the disease. Here, we performed a comprehensive analysis of peripheral blood lymphocyte sub...

  • Article
  • Open Access
14 Citations
5,364 Views
14 Pages

11 May 2018

Awareness of patients’ and healthy people’s spiritual well-being allows for care professionals to support individual spiritual concerns in a timely and appropriate manner, performing a whole-person approach to care. To date, there have be...

  • Article
  • Open Access
15 Citations
3,957 Views
12 Pages

Antimicrobial Activity of Sorghum Phenolic Extract on Bovine Foodborne and Mastitis-Causing Pathogens

  • Sydney E. Schnur,
  • Raghavendra G. Amachawadi,
  • Giovanna Baca,
  • Sarah Sexton-Bowser,
  • Davina H. Rhodes,
  • Dmitriy Smolensky,
  • Thomas J. Herald,
  • Ramasamy Perumal,
  • Daniel U. Thomson and
  • Tiruvoor G. Nagaraja

Antimicrobial resistance in bacterial pathogens associated with bovine mastitis and human foodborne illnesses from contaminated food and water have an impact on animal and human health. Phenolic compounds have antimicrobial properties and some specia...

  • Article
  • Open Access
1,682 Views
10 Pages

Functioning in an Illness and Quality of Life versus the Prevalence of Depression and Anxiety Disorders in Patients with High Cardiovascular Risk

  • Piotr Michalski,
  • Agata Kosobucka-Ozdoba,
  • Łukasz Pietrzykowski,
  • Michał Kasprzak,
  • Klaudyna Grzelakowska,
  • Alicja Rzepka-Cholasińska and
  • Aldona Kubica

23 September 2024

Background: A chronic disease occurring in a person’s life is a stressor, disrupting every aspect of their life. Objectives: This study aims to assess the relationship between functioning in chronic illness and quality of life with the prevalen...

  • Article
  • Open Access
1 Citations
8,655 Views
15 Pages

Autonomic Dysfunction in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS): Findings from the Multi-Site Clinical Assessment of ME/CFS (MCAM) Study in the USA

  • Anindita Issa,
  • Jin-Mann S. Lin,
  • Yang Chen,
  • Jacob Attell,
  • Dana Brimmer,
  • Jeanne Bertolli,
  • Benjamin H. Natelson,
  • Charles W. Lapp,
  • Richard N. Podell and
  • Elizabeth R. Unger
  • + 4 authors

5 September 2025

Background/Objectives: Symptoms of autonomic dysfunction are common in infection-associated chronic conditions and illnesses (IACCIs), including myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). This study aimed to evaluate autonomic sympt...

  • Feature Paper
  • Article
  • Open Access
1 Citations
2,955 Views
8 Pages

18 July 2022

One of the mysteries of traditional Chinese medicine (TCM) is the metaphorical language it uses in describing conditions of the body. The human body is seen as an integrated system operating within the larger context of the natural system. Illnesses...

  • Article
  • Open Access
4 Citations
2,614 Views
14 Pages

Effects of Tocilizumab on Inflammation and Iron Metabolism in Critically Ill Patients with COVID-19

  • Robert Szabo,
  • Cristina Petrișor,
  • Constantin Bodolea,
  • Vlad Dobre,
  • Sebastian Tranca,
  • Simona Clichici,
  • Iulia Szabo,
  • Razvan Marian Melinte and
  • Teodora Mocan

COVID-19 produces cytokine-mediated persistent inflammation and is associated with elevated iron stores and low circulating iron. It is believed that central to the pathophysiological mechanism is interleukin 6 and hepcidin. A state of iron overload,...

  • Article
  • Open Access
12 Citations
3,714 Views
12 Pages

The Impact of COVID-19 on Menstrual Cycle in Women

  • Grzegorz Błażejewski and
  • Joanna Witkoś

29 July 2023

Background: The COVID-19 pandemic has become the largest and most diverse to threaten the health of humanity since the 1918 influenza pandemic. Methods: This study involved 113 women who had suffered from COVID-19. The study was conducted as intervie...

  • Article
  • Open Access
1 Citations
1,177 Views
16 Pages

Soluble Urokinase Plasminogen Activator Receptor: A Promising Biomarker for Mortality Prediction Among Critical ED Patients

  • Piotr Wozniak,
  • Mariusz Sieminski,
  • Jan Pyrzowski,
  • Rafael Petrosjan,
  • Jakub Głogowski-Kulasza and
  • Jakub Leszczyński-Czeczatka

13 February 2025

Patients admitted to the emergency department (ED) are a highly diverse group in terms of the risk of death. In overcrowded EDs, it becomes crucial to quickly and reliably estimate the risk of death or significant health deterioration. For this purpo...

  • Article
  • Open Access
10 Citations
5,386 Views
12 Pages

Antecedents of Psychological Well-Being among Swedish Audit Firm Employees

  • Pernilla Broberg,
  • Torbjörn Tagesson and
  • Timur Uman

The attractiveness of audit firms as employers appears to have decreased in recent years and the audit profession is currently experiencing high employee turnover. A shortage of personnel increases the risk of long-term stress and illness. This paper...

  • Article
  • Open Access
6 Citations
3,320 Views
13 Pages

Measurement Invariance of the Self-Stigma of Mental Illness Scale: A Cross-Cultural Study

  • Shengnan Li,
  • Patrick J. Heath,
  • Carlos A. Vidales,
  • David L. Vogel and
  • Yangang Nie

The current study assessed the measurement invariance of the Self-stigma of Mental Illness scale (SSOMI) across Chinese and US samples and assessed whether the SSOMI differentially relates to distress levels across Chinese and US participants. We inc...

  • Article
  • Open Access
2 Citations
2,593 Views
9 Pages

Presence of Flavivirus Antibodies Does Not Lead to a Greater Number of Symptoms in a Small Cohort of Canadian Travelers Infected with Zika Virus

  • Robert A. Kozak,
  • Lee W. Goneau,
  • Cedric DeLima,
  • Olivia Varsaneux,
  • AliReza Eshaghi,
  • Erik Kristjanson,
  • Romy Olsha,
  • David Safronetz,
  • Stephen Perusini and
  • Jonathan B. Gubbay
  • + 1 author

24 January 2020

Zika virus (ZIKV) is a mosquito-borne flavivirus associated with a febrile illness as well as severe complications, including microcephaly and Guillain-Barré Syndrome. Antibody cross-reactivity between flaviviruses has been documented, and in...

  • Article
  • Open Access
2 Citations
4,681 Views
24 Pages

Contours of Positive Mental Health: An Exploratory Delphi Study from India

  • Diptarup Chowdhury,
  • Ahalya Raguram and
  • Seema Mehrotra

26 June 2019

The need to broaden attention from a narrow focus on mental illness and pathology to investing in understanding and enhancing positive mental health is well recognized. The bulk of research on positive mental health tends to be largely based onwester...

  • Review
  • Open Access
335 Views
22 Pages

This narrative review examines how immersive virtual and mixed-reality (VR/MR) technologies, combined with AI-driven virtual agents, can support the prevention and long-term management of chronic illness. Chronic diseases represent a significant glob...

  • Article
  • Open Access
13 Citations
8,469 Views
10 Pages

23 June 2016

Many consumers do not follow recommended food safety practices for cooking egg dishes, such as pies, quiches, and casseroles, potentially leading to foodborne illnesses such as Salmonellosis. The United States Department of Agriculture (USDA) recomme...

  • Article
  • Open Access
4 Citations
2,224 Views
15 Pages

Bedside Hyperspectral Imaging and Organ Dysfunction Severity in Critically Ill COVID-19 Patients—A Prospective, Monocentric Observational Study

  • Henning Kuhlmann,
  • Lena Garczarek,
  • David Künne,
  • Kevin Pattberg,
  • Annabell Skarabis,
  • Mirjam Frank,
  • Börge Schmidt,
  • Sven Arends,
  • Frank Herbstreit and
  • Florian Espeter
  • + 2 authors

Hyperspectral imaging (HSI) is a non-invasive technology that provides information on biochemical tissue properties, including skin oxygenation and perfusion quality. Microcirculatory alterations are associated with organ dysfunction in septic COVID-...

  • Article
  • Open Access
1,421 Views
12 Pages

26 February 2025

In intensive care units (ICUs), serum lactate and methemoglobin (metHb) levels are considered significant biomarkers for predicting mortality in critically ill patients. This study investigates the relationship between lactate and metHb levels in blo...

  • Article
  • Open Access
13 Citations
2,343 Views
10 Pages

Investigating the Reasons for Receiving the Second Booster Dose of the COVID-19 Vaccine in Adults and in People with Chronic Medical Conditions in Southern Italy

  • Grazia Miraglia del Giudice,
  • Lucio Folcarelli,
  • Giorgia Della Polla,
  • Annalisa Napoli and
  • Italo Francesco Angelillo

27 March 2023

This cross-sectional survey explored the attitudes and the reasons, as well their associated factors, for receiving the second booster dose of the COVID-19 vaccine among a sample of all old adults and of people with chronic medical conditions attendi...

  • Article
  • Open Access
20 Citations
4,109 Views
17 Pages

Background: Associations of early antibiotics exposures with childhood asthma, allergies, and airway illnesses are debated. Objectives: We aimed to investigate associations of first-year antibiotics exposure with childhood asthma, allergies, and airw...

  • Article
  • Open Access
2 Citations
2,073 Views
11 Pages

23 November 2022

In the context of COVID-19 outcomes, global data have deduced a gender bias towards severe disease among males. The aim is to compare morbidity and mortality during two years of the COVID-19 pandemic in female and male patients with COVID-19, as well...

  • Review
  • Open Access
11 Citations
6,069 Views
29 Pages

A context-specific delineation of research approaches to resilience in the perinatal and early motherhood literature is currently lacking. A principle-based concept analysis was used to establish a description of how women’s resilience is curre...

  • Opinion
  • Open Access
1 Citations
1,868 Views
6 Pages

24 August 2024

Recent studies have documented prolonged expression of viral antigens and RNA and associated inflammation after infection with SARS-CoV-2 in a substantial proportion of infected patients. The persisting SARS-CoV-2 effects and findings, with inflammat...

  • Review
  • Open Access
30 Citations
6,132 Views
31 Pages

Viruses, Autophagy Genes, and Crohn’s Disease

  • Vanessa M. Hubbard and
  • Ken Cadwell

21 July 2011

The etiology of the intestinal disease Crohn’s disease involves genetic factors as well as ill-defined environmental agents. Several genetic variants linked to this disease are associated with autophagy, a process that is critical for proper response...

  • Article
  • Open Access
5 Citations
3,373 Views
13 Pages

Bartonella bacilliformis is the causal agent of Carrion’s disease, an overlooked illness endemic in the Andean Mountains with Peru being the most affected country. The diagnostic of this illness is a challenge due to the limited resources and the com...

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