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  • Article
  • Open Access
9 Citations
4,428 Views
14 Pages

The Association between Intracranial Calcifications and Symptoms in Patients with Primary Familial Brain Calcification

  • Gini Mathijssen,
  • Evelien van Valen,
  • Pim A. de Jong,
  • Nienke M. S. Golüke,
  • Emiel A. van Maren,
  • Birgitta M. G. Snijders,
  • Eva H. Brilstra,
  • Ynte M. Ruigrok,
  • Susan Bakker and
  • Huiberdina L. Koek
  • + 2 authors

31 January 2024

(1) Background: Primary Familial Brain Calcification (PFBC) is a neurodegenerative disease characterized by bilateral calcifications of the basal ganglia and other intracranial areas. Many patients experience symptoms of motor dysfunction and cogniti...

  • Article
  • Open Access
683 Views
15 Pages

Vascular Calcification Patterns in the Elderly: Correlation Between Aortic and Iliac Calcification Burden

  • Maximilian Lutz,
  • Malik Galijasevic,
  • Richard A. Lindtner,
  • Andreas E. Ellmerer,
  • David Wippel,
  • Elke R. Gizewski,
  • Stephanie Mangesius,
  • Dietmar Krappinger and
  • Alexander Loizides

11 December 2025

Background: Vascular calcification is a frequent consequence of ageing and is associated with an increased risk of cardiovascular disease. This study aimed to compare two rapid scoring systems for quantifying calcification of the distal abdominal aor...

  • Article
  • Open Access
3 Citations
3,604 Views
21 Pages

The Correlation between the Vascular Calcification Score of the Coronary Artery and the Abdominal Aorta in Patients with Psoriasis

  • Trang Nguyen-Mai Huynh,
  • Fumikazu Yamazaki,
  • Izumi Kishimoto,
  • Akihiro Tanaka,
  • Yonsu Son,
  • Yoshio Ozaki,
  • Kazuya Takehana and
  • Hideaki Tanizaki

Psoriasis is known as an independent risk factor for cardiovascular disease due to its chronic inflammation. Studies have been conducted to evaluate the progress of atherosclerotic plaques in psoriasis. However, inadequate efforts have been made to c...

  • Article
  • Open Access
2 Citations
2,214 Views
9 Pages

Association of the Calcification Score of the Abdominal Aorta, Common Iliac, and Renal Arteries with Outcomes in Living Kidney Donors

  • Luís Costa Ribeiro,
  • Manuela Almeida,
  • Jorge Malheiro,
  • Filipa Silva,
  • Diogo Nunes-Carneiro,
  • La Salete Martins,
  • Sofia Pedroso and
  • Miguel Silva-Ramos

Background: Vascular calcification is an ever-more-common finding in protocoled pre-transplant imaging in living kidney donors. We intended to explore whether a connection could be found between the Agatston calcification score, prior to kidney donat...

  • Article
  • Open Access
11 Citations
3,615 Views
13 Pages

Association between the Severity of Nonalcoholic Fatty Liver Disease and the Risk of Coronary Artery Calcification

  • Chien-Chih Chen,
  • Wei-Chien Hsu,
  • Han-Ming Wu,
  • Jiun-Yi Wang,
  • Pei-Yu Yang and
  • I-Ching Lin

6 August 2021

Background and Objectives: There are limited data on the association between severity of non-alcoholic fatty liver disease (NAFLD) and coronary artery calcification. This study investigated sonographic diagnosed NAFLD and coronary artery calcium scor...

  • Article
  • Open Access
954 Views
11 Pages

Coronary Artery Calcification in Patients with Radiographic Axial Spondyloarthritis: A Comparative Study with Matched Controls in Southwestern Sweden

  • Erik Hulander,
  • Anna Deminger,
  • Sofia Enegren,
  • Magnus Hallström,
  • Caroline Feldthusen,
  • Erika Fagman,
  • Oskar Angerås,
  • Tatiana Zverkova Sandström,
  • Mats Geijer and
  • Helena Forsblad-d’Elia

Radiographic axial spondyloarthritis (r-axSpA) is associated with increased cardiovascular disease (CVD) risk. The coronary artery calcification (CAC) score, an atherosclerosis burden indicator that predicts CVD risk, is not well studied in r-axSpA....

  • Article
  • Open Access
2,044 Views
10 Pages

Clinical and Radiological Outcomes of Ultrasound-Guided Closed-Circuit Irrigation of Calcific Tendinitis of the Shoulder: A Prospective Study

  • Andrea De Grandis,
  • Carlo D’Alessandro,
  • Giovanni Sussan,
  • Alberto Crimì,
  • Lucrezia Tognolo,
  • Daniele Coraci,
  • Stefano Masiero,
  • Roberto Ragazzi,
  • Emilio Quaia and
  • Filippo Crimì

16 August 2025

Ultrasound-guided percutaneous interventions are well-established as effective treatments for shoulder calcific tendinopathy. In this work, we modified the conventional double-needle approach by incorporating a closed-circuit irrigation system and as...

  • Article
  • Open Access
8 Citations
7,707 Views
15 Pages

End-to-End Calcification Distribution Pattern Recognition for Mammograms: An Interpretable Approach with GNN

  • Melissa Min-Szu Yao,
  • Hao Du,
  • Mikael Hartman,
  • Wing P. Chan and
  • Mengling Feng

Purpose: We aimed to develop a novel interpretable artificial intelligence (AI) model algorithm focusing on automatic detection and classification of various patterns of calcification distribution in mammographic images using a unique graph convoluti...

  • Article
  • Open Access
4 Citations
4,250 Views
8 Pages

Cerebral Microbleeds in a Stroke Prevention Clinic

  • A-Hyun Cho,
  • Lara Wadi,
  • Daniel Chow,
  • Peter Chang,
  • David Floriolli,
  • Krunal Shah,
  • Annlia Paganini-Hill and
  • Mark Fisher

The objective of this study was to assess the effectiveness of a stroke clinic in stroke prevention and progression of cerebral microbleeds (CMB). We conducted a retrospective observational study of patients who visited a stroke clinic between Januar...

  • Article
  • Open Access
8 Citations
2,497 Views
13 Pages

To investigate the performance of deep-learning-based algorithms for the automatic segmentation and quantification of abdominal aortic calcification (AAC) in lateral lumbar radiographs, we retrospectively collected 1359 consecutive lateral lumbar rad...

  • Systematic Review
  • Open Access
10 Citations
3,637 Views
14 Pages

Objective Methods to Assess Aorto-Iliac Calcifications: A Systematic Review

  • Anna Fornasari,
  • Salomé Kuntz,
  • Chiara Martini,
  • Paolo Perini,
  • Elisa Cabrini,
  • Antonio Freyrie,
  • Anne Lejay and
  • Nabil Chakfé

Vascular calcifications in aorto-iliac arteries are emerging as crucial risk factors for cardiovascular diseases (CVDs) with profound clinical implications. This systematic review, following PRISMA guidelines, investigated methodologies for measuring...

  • Article
  • Open Access
1 Citations
2,412 Views
15 Pages

Looking into the Eyes to See the Heart of Chronic Kidney Disease Patients

  • Maria Kislikova,
  • Jorge Javier Gaitán-Valdizán,
  • José Antonio Parra Blanco,
  • María Teresa García Unzueta,
  • María Rodríguez Vidriales,
  • Clara Escagedo Cagigas,
  • Vicente Celestino Piñera Haces,
  • María de la Oliva Valentín Muñoz,
  • Adalberto Benito Hernández and
  • Emilio Rodrigo Calabia
  • + 1 author

22 April 2024

In patients with chronic kidney disease (CKD), the main cause of morbidity and mortality is cardiovascular disease (CVD). Both coronary artery calcium scoring by computed tomography (CT) and optical coherence tomography (OCT) are used to identify pat...

  • Article
  • Open Access
5 Citations
4,244 Views
16 Pages

Three Signs to Help Detect Sjögren’s Syndrome: Incidental Findings on Magnetic Resonance Imaging and Computed Tomography

  • Yukinori Takagi,
  • Ikuo Katayama,
  • Sato Eida,
  • Miho Sasaki,
  • Toshimasa Shimizu,
  • Shuntaro Sato,
  • Kunio Hashimoto,
  • Hiroki Mori,
  • Mitsunobu Otsuru and
  • Misa Sumi
  • + 4 authors

12 October 2023

This study aimed to retrospectively investigate the prevalence of Sjögren’s syndrome (SS) among patients with ranulas, parotid cysts, or parotid calcifications; identify the characteristic magnetic resonance imaging (MRI) or computed tomog...

  • Article
  • Open Access
3 Citations
2,942 Views
10 Pages

Quantification of Aortic Valve Calcification in Contrast-Enhanced Computed Tomography

  • Danai Laohachewin,
  • Philipp Ruile,
  • Philipp Breitbart,
  • Jan Minners,
  • Nikolaus Jander,
  • Martin Soschynski,
  • Christopher L. Schlett,
  • Franz-Josef Neumann,
  • Dirk Westermann and
  • Manuel Hein

19 April 2024

Background: The goal of our study is to evaluate a method to quantify aortic valve calcification (AVC) in contrast-enhanced computed tomography for patients with suspected severe aortic stenosis pre-interventionally. Methods: A total of sixty-five pa...

  • Article
  • Open Access
3 Citations
2,300 Views
9 Pages

Intra-Cranial Arterial Calcifications in Hemodialysis Patients

  • Feda Fanadka,
  • Ilan Rozenberg,
  • Naomi Nacasch,
  • Yael Einbinder,
  • Sydney Benchetrit,
  • Ori Wand,
  • Tammy Hod and
  • Keren Cohen-Hagai

24 September 2023

Background and objectives: Vascular calcification is an integral part of atherosclerosis and has been reported to be an independent risk factor for cardiovascular diSsease. Intra Cranial Arterial Calcifications (ICAC) in maintenance hemodialysis (MHD...

  • Article
  • Open Access
344 Views
14 Pages

Clinical and Metabolic Predictors of Response to Focused Extracorporeal Shockwave Therapy in Rotator Cuff Tendinopathy: A Retrospective Cohort Study

  • Sveva Maria Nusca,
  • Eleonora Latini,
  • Gabriele Santilli,
  • Gioia Beccarini,
  • Valerio Bova,
  • Flavia Santoboni,
  • Valter Santilli,
  • Giorgio Felzani,
  • Fabrizio Perroni and
  • Mario Vetrano
  • + 2 authors

27 February 2026

Background: Rotator cuff tendinopathy is a major cause of shoulder pain and disability. Focused extracorporeal shockwave therapy (ESWT) is an established conservative treatment option; however, the predictive factors influencing the treatment respons...

  • Article
  • Open Access
9 Citations
3,505 Views
16 Pages

Comparative Gut Microbiome Differences between High and Low Aortic Arch Calcification Score in Patients with Chronic Diseases

  • Yi-Hsueh Liu,
  • Po Peng,
  • Wei-Chun Hung,
  • Ping-Hsun Wu,
  • Cheng-Yuan Kao,
  • Pei-Yu Wu,
  • Jiun-Chi Huang,
  • Chih-Hsing Hung,
  • Ho-Ming Su and
  • Chao-Hung Kuo
  • + 1 author

Gut dysbiosis can induce chronic inflammation and contribute to atherosclerosis and vascular calcification. The aortic arch calcification (AoAC) score is a simple, noninvasive, and semiquantitative assessment tool to evaluate vascular calcification o...

  • Article
  • Open Access
10 Citations
2,554 Views
14 Pages

Analysis of Epicardial Adipose Tissue Texture in Relation to Coronary Artery Calcification in PCCT: The EAT Signature!

  • Peter Mundt,
  • Alexander Hertel,
  • Hishan Tharmaseelan,
  • Dominik Nörenberg,
  • Theano Papavassiliu,
  • Stefan O. Schoenberg,
  • Matthias F. Froelich and
  • Isabelle Ayx

(1) Background: Epicardial adipose tissue influences cardiac biology in physiological and pathological terms. As it is suspected to be linked to coronary artery calcification, identifying improved methods of diagnostics for these patients is importan...

  • Article
  • Open Access
10 Citations
2,912 Views
14 Pages

Osteoprotegerin Is a Better Predictor for Cardiovascular and All-Cause Mortality than Vascular Calcifications in a Multicenter Cohort of Patients on Peritoneal Dialysis

  • Marcela Ávila,
  • Ma. del Carmen Prado,
  • Renata Romero,
  • Ricardo Córdova,
  • Ma. del Carmen Rigo,
  • Miguel Trejo,
  • Carmen Mora,
  • Ramón Paniagua and
  • for the Mexican Nephrology Collaborative Study Group

8 April 2022

The purpose of this study was to compare vascular calcification (VC), serum osteoprotegerin (OPG) levels, and other biochemical markers to determine their value as available predictors of all-cause and cardiovascular (CV) mortality in patients on per...

  • Article
  • Open Access
1 Citations
739 Views
16 Pages

21 November 2025

Background/Objectives: Arterial stiffness increases with progressive worsening of renal function and predicts cardiovascular mortality in patients with chronic kidney disease. The effects of vitamin K-dependent proteins in vascular health and the imp...

  • Article
  • Open Access
9 Citations
4,124 Views
14 Pages

9 December 2021

Circulating alkaline phosphatase (ALP) is an independent cardiovascular risk marker. Serum bone ALP (BALP) isoforms indicate bone turnover and comprise approximately 50% of total circulating ALP. In chronic kidney disease (CKD), mortality is highest...

  • Article
  • Open Access
28 Citations
11,620 Views
12 Pages

Fruit Intake and Abdominal Aortic Calcification in Elderly Women: A Prospective Cohort Study

  • Nicola P. Bondonno,
  • Joshua R. Lewis,
  • Richard L. Prince,
  • Wai H. Lim,
  • Germaine Wong,
  • John T. Schousboe,
  • Richard J. Woodman,
  • Douglas P. Kiel,
  • Catherine P. Bondonno and
  • Jonathan M. Hodgson
  • + 2 authors

10 March 2016

Cardiovascular disease (CVD) is the leading cause of death worldwide. There is a consistent inverse relationship between fruit intake with CVD events and mortality in cross-sectional and prospective observational studies, but the relationship of frui...

  • Article
  • Open Access
3 Citations
4,142 Views
12 Pages

Thoracic Aortic Calcification and Pre-Clinical Hypertension by New 2017 ACC/AHA Hypertension Guidelines

  • Ya-Ting Jan,
  • Pei-Shan Tsai,
  • Chris T. Longenecker,
  • Dao-Chen Lin,
  • Chun-Ho Yun,
  • Kuo-Tzu Sung,
  • Chuan-Chuan Liu,
  • Jen-Yuan Kuo,
  • Chung-Lieh Hung and
  • Aaron So
  • + 5 authors

The recently revised 2017 American College of Cardiology/American Heart Association (ACC/AHA) hypertension (HTN) guidelines employ a lower blood pressure threshold to define HTN, aiming for earlier prevention of HTN-related cardiovascular diseases (C...

  • Article
  • Open Access
5 Citations
2,940 Views
14 Pages

Global Oxidative Status Is Linked to Calcific Aortic Stenosis: The Differences Due to Diabetes Mellitus and the Effects of Metformin

  • Nerea Corbacho-Alonso,
  • Elena Rodríguez-Sánchez,
  • Tamara Sastre-Oliva,
  • Elisa Mercado-García,
  • Ines Perales-Sánchez,
  • Cristina Juarez-Alia,
  • Luis F. López-Almodovar,
  • Luis R. Padial,
  • Teresa Tejerina and
  • María G. Barderas
  • + 2 authors

28 April 2023

Calcific aortic stenosis (CAS) and type 2 diabetes mellitus (T2DM) are related and often concomitant pathologies, accompanied by common comorbidities such as hypertension or dyslipidemia. Oxidative stress is one of the mechanisms that trigger CAS, an...

  • Article
  • Open Access
4 Citations
2,893 Views
12 Pages

Vascular Calcification Is Associated with Fetuin-A and Cortical Bone Porosity in Stone Formers

  • Fernanda Guedes Rodrigues,
  • Rodrigo Fernandes Carvalho Azambuja Neves,
  • Milene Subtil Ormanji,
  • Priscila Ligeiro Gonçalves Esper,
  • Melissa Gaspar,
  • Rosa Maria Rodrigues Pereira,
  • Lucio R. Requião-Moura,
  • Martin H. de Borst and
  • Ita Pfeferman Heilberg

10 July 2022

Background: Nephrolithiasis has been associated with bone loss and vascular calcification (VC), reflecting abnormal extraosseous calcium deposition. Fetuin-A (Fet-A) acts as a potent inhibitor of ectopic mineralization. The aim of the present study w...

  • Article
  • Open Access
1 Citations
2,108 Views
12 Pages

Patient-Level Pericoronary Adipose Tissue Mean Attenuation: Associations with Plaque Characteristics

  • Katrine Schultz Overgaard,
  • Thomas Rueskov Andersen,
  • Roda Abdulkadir Mohamed,
  • Sebastian Villesen Kristensen,
  • Helle Precht,
  • Jess Lambrechtsen,
  • Søren Auscher and
  • Kenneth Egstrup

Pericoronary adipose tissue attenuation (PCATa), observed from coronary computed tomography angiography (CCTA), is emerging as an inflammation marker. This study evaluated the relationship between PCATa and plaque characteristics, including plaque ty...

  • Article
  • Open Access
7 Citations
2,207 Views
12 Pages

Radiological Features for Frailty Assessment in Patients Requiring Emergency Laparotomy

  • Katarzyna Kołodziejska,
  • Jan Witowski,
  • Piotr Tylec,
  • Anna Grochowska,
  • Natalia Przytuła,
  • Maciej Lis,
  • Michał Pędziwiatr and
  • Mateusz Rubinkiewicz

13 September 2022

Introduction: As the number of elderly patients requiring surgical intervention rises, it is believed that frailty syndrome has a greater impact on perioperative course than on chronological age. The aim of this study was to evaluate the efficacy of...

  • Article
  • Open Access
2 Citations
2,325 Views
12 Pages

Gla-Rich Protein Is Associated with Vascular Calcification, Inflammation, and Mineral Markers in Peritoneal Dialysis Patients

  • Catarina Marreiros,
  • Carla Viegas,
  • Anabela Malho Guedes,
  • Ana Paula Silva,
  • Ana Catarina Águas,
  • Marília Faísca,
  • Leon Schurgers and
  • Dina Costa Simes

6 December 2024

Background/Objectives: Vascular calcification (VC) is a crucial risk factor for cardiovascular diseases (CVD), particularly in chronic kidney disease (CKD) populations. However, the specific relationship between VC and end-stage renal disease (ESRD)...

  • Article
  • Open Access
5 Citations
3,245 Views
8 Pages

21 April 2022

Enthesitis is a key pathology in spondyloarthritis (SpA), but diagnosis may be clinically challenging. The objective of this study was to investigate the prevalence of ultrasound enthesitis lesions in tender entheses in the heel region in patients wi...

  • Article
  • Open Access
10 Citations
2,581 Views
13 Pages

Cerebrovascular Events after Transcatheter Aortic Valve Replacement: The Difficulty in Predicting the Unpredictable

  • Oliver Maier,
  • Georg Bosbach,
  • Kerstin Piayda,
  • Shazia Afzal,
  • Amin Polzin,
  • Ralf Westenfeld,
  • Christian Jung,
  • Malte Kelm,
  • Tobias Zeus and
  • Verena Veulemans

4 July 2022

Background: Cerebrovascular events (CVE) are feared complications following transcatheter aortic valve replacement (TAVR). We aimed to develop a new risk model for CVE prediction with the application of multimodal imaging. Methods: From May 2011 to A...

  • Article
  • Open Access
373 Views
13 Pages

Comparison of Carotid Plaque Ultrasound and Computed Tomography in Patients and Ex Vivo Specimens—Agreement of Composition Analysis

  • Simon Stemmler,
  • Martin Soschynski,
  • Martin Czerny,
  • Thomas Zeller,
  • Dirk Westermann and
  • Roland-Richard Macharzina

9 January 2026

Background: Carotid plaque composition is central to stroke risk, but some aspects of plaque characterization are derived from ex vivo imaging, while clinical decision-making relies on in vivo ultrasound (US) and computed tomography (CT). High correl...

  • Article
  • Open Access
6 Citations
2,912 Views
15 Pages

18 August 2022

Several studies have identified improvements in the risks of cardiovascular disease in adults following a Mediterranean dietary pattern. However, data are scarce on its association with coronary artery calcification (CAC) and pericardial adiposity (P...

  • Article
  • Open Access
10 Citations
3,042 Views
11 Pages

New Model for Predicting the Presence of Coronary Artery Calcification

  • Samel Park,
  • Min Hong,
  • HwaMin Lee,
  • Nam-jun Cho,
  • Eun-Young Lee,
  • Won-Young Lee,
  • Eun-Jung Rhee and
  • Hyo-Wook Gil

25 January 2021

Coronary artery calcification (CAC) is a feature of coronary atherosclerosis and a well-known risk factor for cardiovascular disease (CVD). As the absence of CAC is associated with a lower incidence rate of CVD, measurement of a CAC score is helpful...

  • Article
  • Open Access
11 Citations
3,042 Views
10 Pages

Comparison of Orbital Atherectomy and Rotational Atherectomy in Calcified Left Main Disease: Short-Term Outcomes

  • Piotr Rola,
  • Jan Jakub Kulczycki,
  • Mateusz Barycki,
  • Szymon Włodarczak,
  • Łukasz Furtan,
  • Michalina Kędzierska,
  • Katarzyna Giniewicz,
  • Adrian Doroszko,
  • Maciej Lesiak and
  • Adrian Włodarczak

13 June 2023

Background: Coronary calcifications, particularly in left main disease (LMD), are independently associated with adverse outcomes of percutaneous coronary intervention (PCI). Adequate lesion preparation is pivotal to achieve favorable short- and long-...

  • Article
  • Open Access
2 Citations
2,231 Views
12 Pages

A Propensity-Matched Comparison of Ischemic Brain Lesions on Postprocedural MRI in Endovascular versus Open Carotid Artery Reconstruction

  • Zsuzsanna Mihály,
  • Samuel Booth,
  • Dat Tin Nguyen,
  • Milán Vecsey-Nagy,
  • Miklós Vértes,
  • Zsófia Czinege,
  • Csongor Péter,
  • Péter Sótonyi and
  • Andrea Varga

(1) Study purpose: The aim of our prospective single-center, matched case–control study was to compare the number and volume of acute ischemic brain lesions following carotid endarterectomy (CEA) versus carotid artery stenting (CAS) using a pro...

  • Article
  • Open Access
45 Citations
6,274 Views
15 Pages

High Temporal Resolution Dual-Source Photon-Counting CT for Coronary Artery Disease: Initial Multicenter Clinical Experience

  • Martin Soschynski,
  • Florian Hagen,
  • Stefan Baumann,
  • Muhammad Taha Hagar,
  • Jakob Weiss,
  • Tobias Krauss,
  • Christopher L. Schlett,
  • Constantin von zur Mühlen,
  • Fabian Bamberg and
  • Patrick Krumm
  • + 10 authors

11 October 2022

The aim of this paper is to evaluate the diagnostic image quality of spectral dual-source photon-counting detector coronary computed tomography angiography (PCD-CCTA) for coronary artery disease in a multicenter study. The image quality (IQ), assessa...

  • Article
  • Open Access
5 Citations
3,145 Views
12 Pages

Non-Motor Symptoms in Primary Familial Brain Calcification

  • Giulia Bonato,
  • Paola Cimino,
  • Francesca Pistonesi,
  • Leonardo Salviati,
  • Cinzia Bertolin and
  • Miryam Carecchio

30 June 2024

Background/Objectives: Primary Familial Brain Calcification is a rare neurodegenerative disorder of adulthood characterized by calcium deposition in the basal ganglia and other brain areas; the main clinical manifestations include movement disorders,...

  • Article
  • Open Access
14 Citations
2,991 Views
12 Pages

Machine Learning for Prediction of Technical Results of Percutaneous Coronary Intervention for Chronic Total Occlusion

  • Tatsuya Nakachi,
  • Masahisa Yamane,
  • Koichi Kishi,
  • Toshiya Muramatsu,
  • Hisayuki Okada,
  • Yuji Oikawa,
  • Ryohei Yoshikawa,
  • Tomohiro Kawasaki,
  • Hiroyuki Tanaka and
  • Osamu Katoh

9 May 2023

(1) Background: The probability of technical success in percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) represents essential information for specifying the priority of PCI for treatment selection in patients with CTO. Howev...

  • Article
  • Open Access
14 Citations
3,336 Views
13 Pages

Gender Differences in the Atherosclerosis Profile by Coronary CTA in Coronary Artery Calcium Score Zero Patients

  • Thomas Senoner,
  • Fabian Plank,
  • Christoph Beyer,
  • Christian Langer,
  • Katharina Birkl,
  • Fabian Steinkohl,
  • Gerlig Widmann,
  • Fabian Barbieri,
  • Agne Adukauskaite and
  • Gudrun M. Feuchtner
  • + 3 authors

15 March 2021

Background: The coronary artery calcium score (CACS) is a powerful tool for cardiovascular risk stratification. Coronary computed tomography angiography (CTA) allows for a more distinct analysis of atherosclerosis. The aim of the study was to assess...

  • Article
  • Open Access
1 Citations
2,251 Views
12 Pages

Diagnostic Ability of Manual Calcification Length Assessment on Non-Electrocardiographically Gated Computed Tomography for Estimating the Presence of Coronary Artery Disease

  • Ryota Watanabe,
  • Yuichi Saito,
  • Satoshi Tokimasa,
  • Hiroyuki Takaoka,
  • Hideki Kitahara,
  • Masato Yamanouchi and
  • Yoshio Kobayashi

12 April 2024

Background: Coronary artery calcification score (CACS) on electrocardiography (ECG)-gated computed tomography (CT) is used for risk stratification of atherosclerotic cardiovascular disease, which requires dedicated analytic software. In this study, w...

  • Article
  • Open Access
1,775 Views
24 Pages

Quantitative Ultrasound-Based Precision Diagnosis of Papillary, Follicular, and Medullary Thyroid Carcinomas Using Morphological, Structural, and Textural Features

  • Hanna Piotrzkowska Wróblewska,
  • Piotr Karwat,
  • Agnieszka Żyłka,
  • Katarzyna Dobruch Sobczak,
  • Marek Dedecjus and
  • Jerzy Litniewski

24 August 2025

Background/Objectives: Thyroid cancer encompasses distinct histological subtypes with varying biological behavior and treatment implications. Accurate preoperative subtype differentiation remains challenging. Although ultrasound (US) is widely used f...

  • Article
  • Open Access
6 Citations
2,263 Views
20 Pages

Prediction of Surgical Approach in Mitral Valve Disease by XGBoost Algorithm Based on Echocardiographic Features

  • Xiaoxuan Lin,
  • Lixin Chen,
  • Defu Zhang,
  • Shuyu Luo,
  • Yuanyuan Sheng,
  • Xiaohua Liu,
  • Qian Liu,
  • Jian Li,
  • Bobo Shi and
  • Yingying Liu
  • + 8 authors

2 February 2023

In this study, we aimed to develop a prediction model to assist surgeons in choosing an appropriate surgical approach for mitral valve disease patients. We retrospectively analyzed a total of 143 patients who underwent surgery for mitral valve diseas...

  • Article
  • Open Access
14 Citations
3,465 Views
14 Pages

Lanthionine, a Novel Uremic Toxin, in the Vascular Calcification of Chronic Kidney Disease: The Role of Proinflammatory Cytokines

  • Alessandra Fortunata Perna,
  • Luigi Russo,
  • Vittoria D’Esposito,
  • Pietro Formisano,
  • Dario Bruzzese,
  • Carmela Vigorito,
  • Annapaola Coppola,
  • Patrizia Lombari,
  • Domenico Russo and
  • Diego Ingrosso

Vascular calcification (VC) is a risk factor for cardiovascular events and mortality in chronic kidney disease (CKD). Several components influence the occurrence of VC, among which inflammation. A novel uremic toxin, lanthionine, was shown to increas...

  • Article
  • Open Access
4 Citations
3,241 Views
19 Pages

Epicardial Adipose Tissue Volume Assessment in the General Population and CAD-RADS 2.0 Score Correlation Using Dual Source Cardiac CT

  • Federica Dell’Aversana,
  • Renato Tuccillo,
  • Alessandro Monfregola,
  • Leda De Angelis,
  • Giovanni Ferrandino,
  • Carlo Tedeschi,
  • Fulvio Cacciapuoti,
  • Fabio Tamburro and
  • Carlo Liguori

Objectives: Our study aims to investigate the correlation between epicardial adipose tissue (EAT) volume assessed with non-contrast cardiac CT (NCCCT) and sex, age, coronary artery disease reporting and data system (CAD-RADS 2.0) categories, and coro...

  • Article
  • Open Access
6 Citations
2,651 Views
13 Pages

26 June 2024

Background and Objectives: Job strain is a psychological, physical, and behavioral stress that occurs at the workplace. Job strain is associated with more than double the normal risk of coronary artery disease (CAD). The main aim of this study was to...

  • Article
  • Open Access
4 Citations
2,109 Views
10 Pages

Coronary Computed Tomography Angiography and Abdominal Aortic Calcification Screening among High-Risk Living Kidney Donors

  • Keren Skalsky,
  • Arthur Shiyovich,
  • Nir Hochwald,
  • Amos Levi,
  • Lutof Zreik,
  • Shlomit Tamir,
  • Gideon Shafir,
  • Anat Briger,
  • Ruth Rahamimov and
  • Ashraf Hamdan
  • + 1 author

7 July 2023

Background: A unique scanning protocol combining coronary computed tomography angiography (CTA) with routine abdominal CTA is being used at the Rabin Medical Center as a method of screening high-risk candidates for living kidney donation. We aim to e...

  • Article
  • Open Access
7 Citations
2,977 Views
14 Pages

Abdominal Aortic Calcification and Cardiovascular Outcomes in Chronic Kidney Disease: Findings from KNOW-CKD Study

  • Sang Heon Suh,
  • Tae Ryom Oh,
  • Hong Sang Choi,
  • Chang Seong Kim,
  • Eun Hui Bae,
  • Kook-Hwan Oh,
  • Joongyub Lee,
  • Yun Kyu Oh,
  • Ji Yong Jung and
  • on behalf of the Korean Cohort Study for Outcomes in Patients with Chronic Kidney Disease (KNOW-CKD) Investigators
  • + 2 authors

22 February 2022

To investigate the association between abdominal aortic calcification score (AACS) assessed by plain radiograph of the lateral abdomen and the risk of cardiovascular (CV) events in patients with pre-dialysis chronic kidney disease (CKD), a total of 2...

  • Article
  • Open Access
16 Citations
4,608 Views
9 Pages

To investigate whether artificial-intelligence-based, computer-aided diagnosis (AI-CAD) could facilitate the detection of missed cancer on digital mammography, a total of 204 women diagnosed with breast cancer with diagnostic (present) and prior mamm...

  • Article
  • Open Access
1,297 Views
11 Pages

The Impact of Epithelial Inflammation in Membrane Remnants on the Outcome of Tympanoplasty

  • María Fernanda Galindo-Tapia,
  • Alejandro Esteban Deras-Quiñones,
  • Itzel Maria Montoya-Fuentes,
  • Eduardo Osiris Madrigal-Santillán,
  • Ángel Morales-González,
  • Naria A. Flores-Fuentes,
  • Liliana Anguiano-Robledo,
  • Raúl Rojas-Martínez,
  • Beatriz Montaño-Velázquez and
  • José A. Morales-González

Background: Chronic otitis media (COM) with tympanic perforation sometimes requires tympanoplasty. Many factors can interfere with surgical success; however, the histological status of the remaining epithelium of the perforation has not been studied...

  • Article
  • Open Access
26 Citations
4,082 Views
11 Pages

19 January 2021

(1) Background: Epi- and Paracardial Adipose Tissue (EAT, PAT) have been spotlighted as important biomarkers in cardiological assessment in recent years. Since biomarker quantification is an increasingly important method for clinical use, we wanted t...

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