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120 Results Found

  • Article
  • Open Access
8 Citations
3,506 Views
13 Pages

Evaluating Drivers of the Patient Experience Triangle: Stress, Anxiety, and Frustration

  • Sumaya Almaazmi,
  • Mecit Can Emre Simsekler,
  • Andreas Henschel,
  • Abroon Qazi,
  • Dounia Marbouh and
  • Rana Adel Mahmoud Ali Luqman

Patient experience is a widely used indicator for assessing the quality-of-care process during a patient’s journey in hospital. However, the literature rarely discusses three components: patient stress, anxiety, and frustration. Furthermore, li...

  • Article
  • Open Access
16 Citations
3,299 Views
16 Pages

22 November 2022

Brain–computer interfaces (BCIs) are successfully used for stroke rehabilitation, but the training is repetitive and patients can lose the motivation to train. Moreover, controlling the BCI may be difficult, which causes frustration and leads t...

  • Article
  • Open Access
1 Citations
1,332 Views
30 Pages

Experience of Virtual Help in a Simulated BCI Stroke Rehabilitation Serious Game and How to Measure It

  • Bastian Ilsø Hougaard,
  • Hendrik Knoche,
  • Mathias Sand Kristensen and
  • Mads Jochumsen

26 April 2025

Designers of digital rehabilitation experiences can accommodate error-prone input devices like brain–computer interfaces (BCIs) by incorporating virtual help mechanisms to adjust the difficulty, but it is unclear on what grounds users are willi...

  • Article
  • Open Access
9 Citations
3,934 Views
16 Pages

Salivary Antioxidant Capacity and Magnesium in Generalized Anxiety Disorder

  • Elena V. Proskurnina,
  • Krystsina M. Liaukovich,
  • Lyubov S. Bychkovskaya,
  • Ivan V. Mikheev,
  • Evgenia I. Alshanskaia,
  • Mikhail A. Proskurnin,
  • Olga V. Martynova and
  • Galina V. Portnova

2 January 2023

Generalized anxiety disorder (GAD) is a prevalent disorder. The search for biomarkers may contribute to new knowledge about molecular pathogenesis and treatment. Since oxidative stress and micronutrient imbalance play a key role in the development of...

  • Article
  • Open Access
9 Citations
2,195 Views
10 Pages

“No One Truly Understands What We Go through and How to Treat It”: Lived Experiences with Medical Providers among Patients with Orofacial Pain

  • Victoria A. Grunberg,
  • Mira Reichman,
  • Brenda C. Lovette,
  • Ana-Maria Vranceanu and
  • Jonathan Greenberg

Orofacial pain affects 10–15% of adults, yet treatments are limited. The gaps in care are frustrating for both patients and providers and can negatively impact patient–provider interactions. These interactions are key because they impact...

  • Article
  • Open Access
7 Citations
3,324 Views
15 Pages

DLC1 as Druggable Target for Specific Subsets of Gastric Cancer: An RNA-seq-Based Study

  • Lianlei Yang,
  • Adil Manzoor Bhat,
  • Sahar Qazi and
  • Khalid Raza

6 March 2023

Background: Gastric cancer has been ranked the third leading cause of cancer death worldwide. Its detection at the early stage is difficult because patients mostly experience vague and non-specific symptoms in the early stages. Methods: The RNA-seq d...

  • Article
  • Open Access
52 Citations
4,535 Views
15 Pages

15 November 2021

Organizations grow and excel with knowledge sharing; on the other hand, knowledge hiding is a negative behavior that impedes innovation, growth, problem solving, and timely correct decision making in organizations. It becomes more critical in the cas...

  • Review
  • Open Access
14 Citations
5,919 Views
8 Pages

Hemorrhoids Embolization: State of the Art and Future Directions

  • Alberto Rebonato,
  • Daniele Maiettini,
  • Alberto Patriti,
  • Francesco Giurazza,
  • Marcello Andrea Tipaldi,
  • Filippo Piacentino,
  • Federico Fontana,
  • Antonio Basile and
  • Massimo Venturini

12 August 2021

Hemorrhoidal disease is a frustrating problem that has a relevant impact on patients’ psychological, social, and physical well-being. Recently, endovascular embolization of hemorrhoids has emerged as a promising mini-invasive solution with respect to...

  • Article
  • Open Access
961 Views
11 Pages

Patients’ Experiences Following Osteoarticular Foot Surgery for Rheumatoid Arthritis-Related Deformities: A Qualitative Study

  • Amparo Campos-Cano,
  • Ana Belen Ortega-Avila,
  • Salvador Diaz-Miguel,
  • Alejandro Castillo-Domínguez,
  • Eva Lopezosa-Reca,
  • Gabriel Gijon-Nogueron,
  • Laura Ramos-Petersen and
  • Andrés Reinoso-Cobo

7 April 2025

Background and Objectives: Rheumatoid arthritis (RA) is a chronic autoimmune disease that frequently causes foot deformities, decreasing mobility and quality of life. Although surgical interventions seek to alleviate these alterations, the long-term...

  • Article
  • Open Access
4 Citations
2,670 Views
15 Pages

26 April 2025

Background: Physical, emotional, psychological, and social factors influence the high level of burden of a caregiver providing care for a patient at home after a stroke. The purpose of this study was to identify and evaluate factors influencing the h...

  • Article
  • Open Access
2 Citations
3,947 Views
9 Pages

18 September 2024

Canada is known to have a complex pathway for new drug approval and reimbursement, resulting in delayed access for patients with serious and life-threatening diseases, such as cancer. Several recent publications from key stakeholders, including patie...

  • Article
  • Open Access
4 Citations
2,836 Views
10 Pages

Predicting a Need for Financial Assistance in Emergency Department Care

  • Samuel Davis,
  • Sara Nourazari,
  • Rachel Granovsky and
  • Nasser Fard

Identifying patients with a low likelihood of paying their bill serves the needs of patients and providers alike: aligning government programs with their target beneficiaries while minimizing patient frustration and reducing waste among emergency phy...

  • Review
  • Open Access
1 Citations
3,047 Views
10 Pages

Surgical Treatment of Post-Traumatic Radio-Ulnar Synostosis

  • Mihai Tudor Gavrilă,
  • Vlad Cristea,
  • Cătălin Gabriel Smarandache and
  • Cristea Ștefan

9 December 2024

Radio-ulnar synostosis is a rare complication which develops following forearm trauma, the main manifestation being stiffness and leading to the loss of pronation and supination. For the patient, it is a very frustrating experience due to the impairm...

  • Article
  • Open Access
2 Citations
2,212 Views
8 Pages

Patients’ Perceptions and Experiences during the Pre-Admission Phase for Total Hip Replacement Surgery: A Qualitative Phenomenological Study

  • Umile Giuseppe Longo,
  • Anna Marchetti,
  • Alessandra Corradini,
  • Vincenzo Candela,
  • Giuseppe Salvatore,
  • Maria Grazia De Marinis and
  • Vincenzo Denaro

7 April 2023

Osteoarthritis negatively impacts the patient’s quality of life. Qualitative research is an effective tool in detecting the various emotions experienced by patients with osteoarthritis. Such studies play a crucial role in promoting comprehensio...

  • Perspective
  • Open Access
1 Citations
296 Views
3 Pages

Introduction (excerpt): Jaw clenching is a commonly reported behavioral reaction to stress; especially anger, pain, and frustration. Some people clench their teeth when about to push or lift heavy objects. Bruxing most typically occurs during the nig...

  • Case Report
  • Open Access
2 Citations
5,527 Views
10 Pages

Managing Wound Healing with a High-Risk Patient: A Case Report

  • Nikolai N. Potekaev,
  • Olga B. Borzykh,
  • German V. Medvedev,
  • Marina M. Petrova,
  • Elena I. Karpova,
  • Maria A. Zatolokina,
  • Mustafa Al-Zamil,
  • Olga M. Demina,
  • Ekaterina A. Narodova and
  • Natalia A. Shnayder

26 February 2022

Wound healing is a complex, multi-step process. This process begins immediately after skin damage. The outcome of wound healing depends on the quality of each stage of this process: a normal or pathological scar. Violation of wound healing entails a...

  • Review
  • Open Access
23 Citations
6,942 Views
9 Pages

Hormesis and Defense of Infectious Disease

  • Sebastian Weis,
  • Ignacio Rubio,
  • Kristin Ludwig,
  • Cynthia Weigel and
  • Elisa Jentho

Infectious diseases are a global health burden and remain associated with high social and economic impact. Treatment of affected patients largely relies on antimicrobial agents that act by directly targeting microbial replication. Despite the utility...

  • Article
  • Open Access
5 Citations
7,089 Views
22 Pages

The Efficacy of Cannabis in Oncology Patient Care and Its Anti-Tumor Effects

  • Walid Shalata,
  • Omar Abu Saleh,
  • Lena Tourkey,
  • Sondos Shalata,
  • Ala Eddin Neime,
  • Ali Abu Juma’a,
  • Arina Soklakova,
  • Lama Tourkey,
  • Ashraf Abu Jama and
  • Alexander Yakobson

21 August 2024

As the legalization of medical cannabis expands across several countries, interest in its potential advantages among cancer patients and caregivers is burgeoning. However, patients seeking to integrate cannabis into their treatment often encounter fr...

  • Article
  • Open Access
3 Citations
2,200 Views
12 Pages

This study applied the Q methodology to explore breast cancer patients’ perceived difficulties in their fight against the disease. We used literature analysis and in-depth interviews and selected 162 statements for the Q population. Then, we ch...

  • Article
  • Open Access
24 Citations
5,750 Views
15 Pages

3 September 2015

Oral mucositis (OM) is among the most undesirable, painful, and expensive toxicities of cytotoxic cancer therapy, and is disheartening for patients and frustrating for caregivers. Accurate assessment of the incidence of OM has been elusive, but accum...

  • Review
  • Open Access
65 Citations
38,425 Views
17 Pages

2 November 2011

Integrating spirituality into mental health care, psychiatry and psychotherapy is still controversial, albeit a growing body of evidence is showing beneficial effects and a real need for such integration. In this review, past and recent research as w...

  • Editorial
  • Open Access
19 Citations
7,569 Views
3 Pages

26 October 2019

Research in the field of sexuality has shown growing scientific development in recent years, although there’s a lack of well-trained professionals who could contribute to increasing its benefits. Sexuality continues to be a taboo with different...

  • Article
  • Open Access
20 Citations
4,442 Views
13 Pages

Caregivers of Patients with Hematological Malignancies within Home Care: A Phenomenological Study

  • Isabella Capodanno,
  • Mirta Rocchi,
  • Rossella Prandi,
  • Cristina Pedroni,
  • Enrica Tamagnini,
  • Pierluigi Alfieri,
  • Francesco Merli and
  • Luca Ghirotto

The role of caregivers in homecare settings is relevant to the patient’s wellbeing and quality of life. This phenomenon is well described in the literature for the oncological setting but not specifically for that of hematological malignancies....

  • Article
  • Open Access
1 Citations
2,915 Views
13 Pages

Fibromyalgia patients experience difficulties in their daily lives that are difficult to identify and recognize due to the stigma associated with the disease. Nurses can help identify them to establish biopsychosocial coping and treatment. The main a...

  • Case Report
  • Open Access
5 Citations
337 Views
5 Pages

Delayed Management of Unrecognized Bilateral Temporomandibular Joint Dislocation: A Case Report

  • Siok Yoong Chin,
  • Nazer Bin Berahim,
  • Khairulzaman Bin Adnan and
  • Sundrarajan Naidu Ramasamy

Temporomandibular joint (TMJ) dislocation is a common occurrence, but diagnosis can be missed if patients do not complain. Delayed presentation complicates the management of a straightforward reduction. We present a case of a 24-year-old man who had...

  • Article
  • Open Access
8 Citations
4,008 Views
9 Pages

The purpose of this study was to describe the meaning of the suffering experience of Korean ALS family caregivers. This is a descriptive phenomenological study that included ten participants using convenience sampling with maximum variation in a tert...

  • Case Report
  • Open Access
2,012 Views
4 Pages

Cognitive and Speech Rehabilitation in a Patient Affected by Takotsubo Cardiomyophathy: A Case Report

  • Francesco Corallo,
  • Lilla Bonanno,
  • Caterina Formica,
  • Valentina Coppola,
  • Marcella Di Cara,
  • Piercataldo D’aleo,
  • Silvia Marino,
  • Chiara Smorto and
  • Viviana Lo Buono

Background and Objectives: Takotsubo Syndrome (TS) constitutes one of the most recent clinical realities in modern cardiology. It is clinically similar to the acute coronary syndrome, in the absence of obstructive coronary artery disease. Case Presen...

  • Article
  • Open Access
3 Citations
3,338 Views
10 Pages

26 February 2021

Failed back surgery syndrome (FBSS) is a commonly encountered disease after lumbar surgery. There are many cases where it is difficult to choose a treatment because no specific cause can be found. Nevertheless, according to recent reports, adhesiolys...

  • Article
  • Open Access
1,886 Views
7 Pages

Medial Rectus Disinsertion for the Management of Large-Angle Sensory Esotropia

  • So Young Han,
  • Bo Young Chun,
  • Hye Jin Lee,
  • Hyun Kyung Kim,
  • Mi Sun Kwon,
  • Ho Seok Lee and
  • Soolienah Rhiu

6 July 2024

Background and Objectives: The aim of the report is to report the outcomes of the medial rectus (MR) disinsertion procedure for the management of large-angle esotropia (ET) patients. Materials and Methods: This is a retrospective case series of patie...

  • Article
  • Open Access
10 Citations
5,963 Views
10 Pages

Patient Opinion of Visiting Therapy Dogs in a Hospital Emergency Department

  • Joanne Reddekopp,
  • Colleen Anne Dell,
  • Betty Rohr,
  • Barbara Fornssler,
  • Maryellen Gibson,
  • Ben Carey and
  • James Stempien

To date there have been no studies examining whether patients want emergency department (ED) therapy dog programs. This patient-oriented study examined the opinions of patients about whether they would want to be visited by a therapy dog in the Royal...

  • Article
  • Open Access
12 Citations
3,151 Views
8 Pages

Cognitive Assessment in GNAO1 Neurodevelopmental Disorder Using an Eye Tracking System

  • Federica Graziola,
  • Giacomo Garone,
  • Melissa Grasso and
  • Alessandro Capuano

12 August 2021

GNAO1 gene mutations are associated with a neurodevelopmental disorder characterized by developmental delay, epilepsy, and movement disorder. Eye tracking and eye movement analysis are an intriguing method to assess cognitive and language function an...

  • Review
  • Open Access
19 Citations
6,954 Views
19 Pages

Experimental Animal Model Systems for Understanding Salivary Secretory Disorders

  • Ji-Youn Kim,
  • Chang-Hyeon An,
  • Jae-Young Kim and
  • Jae-Kwang Jung

10 November 2020

Salivary secretory disorders are life-disrupting pathologic conditions with a high prevalence, especially in the geriatric population. Both patients and clinicians frequently feel helpless and get frustrated by the currently available therapeutic str...

  • Article
  • Open Access
919 Views
14 Pages

23 July 2025

Lou Gehrig’s disease, also known as ALS, is a progressive neurodegenerative condition that weakens muscles and can lead to paralysis as it progresses. For patients with severe paralysis, eye-tracking devices such as eye mouse enable communicati...

  • Article
  • Open Access
1 Citations
4,128 Views
18 Pages

Life beyond Loss: A Retrospective Analysis of the Impact of Meaning of Life Therapy on the Grieving Process of Cancer Patients’ Family Caregivers

  • Maria João Freitas,
  • Sónia Remondes-Costa,
  • Elisa Veiga,
  • Gerly Macedo,
  • Ricardo João Teixeira and
  • Manuela Leite

14 February 2024

Oncological disease in the palliative stage is a huge challenge for patients and their family caregivers (FCs) due to the fact that it confronts them with death, as well as physical, psychological, and existential suffering. Meaning of Life Therapy (...

  • Article
  • Open Access
19 Citations
11,953 Views
15 Pages

There is little information about how clients attending lifestyle modification programs view the outcomes. This qualitative study examined the clients’ experience of a community based lifestyle modification program in Hong Kong. Semi-structured inter...

  • Feature Paper
  • Article
  • Open Access
2,802 Views
12 Pages

17 September 2022

This paper presents a study of the interaction between healthcare providers (HCPs) and older patients and their caregivers. The paper first presents results from a rapid review and narrative synthesis using PubMed and Google Scholar of HCP/patient/ca...

  • Article
  • Open Access
8 Citations
5,029 Views
14 Pages

Access to Oncology Medicines in Canada: Consensus Forum for Recommendations for Improvement

  • Sandeep R. Sehdev,
  • Nigel S. B. Rawson,
  • Olexiy I. Aseyev,
  • Catriona J. Buick,
  • Marcus O. Butler,
  • Scott Edwards,
  • Sharlene Gill,
  • Joanna M. Gotfrit,
  • Cyrus C. Hsia and
  • Pawel G. Zalewski
  • + 9 authors

29 March 2024

Patient access to new oncology drugs in Canada is only possible after navigating multiple sequential systemic checkpoints for national regulatory approval, health technology assessment (HTA) and collective government price negotiation. These steps de...

  • Proceeding Paper
  • Open Access
2 Citations
3,044 Views
3 Pages

Smart Bracelet for Emotional Enhancement in Children with Autism Spectrum Disorder

  • Alba Ortolan-Soto,
  • Juan A. Castro-García,
  • Alberto J. Molina-Cantero,
  • Manuel Merino-Monge and
  • Isabel M. Gómez-González

29 September 2021

People with autism spectrum disorder (ASD) have great difficulties in social interaction and in the management of personal and other people’s emotions. This work aimed at developing an intelligent bracelet, capable of inferring the children’s emotion...

  • Article
  • Open Access
9 Citations
2,753 Views
11 Pages

The Addition of Endometrial Injury to Freeze-All Strategy in Women with Repeated Implantation Failures

  • Ioannis Rigos,
  • Vasileios Athanasiou,
  • Nikolaos Vlahos,
  • Nikolaos Papantoniou,
  • Dimitrios Profer and
  • Charalampos Siristatidis

17 May 2021

(1) Background: Recurrent implantation failure (RIF) after IVF remains a challenging topic for fertility specialists and a frustrating reality for patients with infertility. Various approaches have been investigated and applied towards the improvemen...

  • Article
  • Open Access
9 Citations
12,614 Views
10 Pages

Emergency Room Nurses’ Experiences in Person-Centred Care

  • Jang Mi Kim,
  • Na Geong Kim and
  • Eun Nam Lee

4 July 2022

Implementing person-centred care is often considered difficult in congested emergency rooms. The purpose of this study was to understand person-centred care experienced by emergency room nurses in depth and examine the essence of emergency room nurse...

  • Review
  • Open Access
69 Citations
12,866 Views
15 Pages

Microbiota and Probiotics in Health and HIV Infection

  • Chiara D’Angelo,
  • Marcella Reale and
  • Erica Costantini

16 June 2017

Microbiota play a key role in various body functions, as well as in physiological, metabolic, and immunological processes, through different mechanisms such as the regulation of the development and/or functions of different types of immune cells in t...

  • Article
  • Open Access
25 Citations
3,475 Views
14 Pages

17 March 2021

Background: Adolescents and young adults (AYAs) with cancer are at risk of therapy-induced infertility. The importance of initial and specialized fertility counselling to this patient group is undisputed. Despite international guidelines, oncofertili...

  • Article
  • Open Access
5 Citations
3,039 Views
15 Pages

The Impact and Burden of Chronic Rhinosinusitis with Nasal Polyps on Patients and Their Family Caregivers: A Nationally Representative Survey

  • Luca Malvezzi,
  • Veronica Seccia,
  • Antonio Moffa,
  • Frank Rikki Mauritz Canevari,
  • Ilaria Baiardini,
  • Simona Barbaglia,
  • Mattia Battistini,
  • Eleonora Cantoni,
  • Filippo Cipriani and
  • Eugenio De Corso
  • + 3 authors

17 February 2025

Background: Chronic rhinosinusitis with nasal polyps (CRSwNPs) is a chronic inflammatory disease associated with frustrating symptoms, particularly nasal obstruction and loss of smell. We conducted a patient survey on the significant burden of the di...

  • Article
  • Open Access
1 Citations
11,414 Views
10 Pages

Barriers to Effective Communication between Patients, Relatives, and Health Care Professionals in the Era of COVID-19 Pandemic at Public Hospitals in Limpopo Province

  • Ndidzulafhi Selina Raliphaswa,
  • Dorah Ursula Ramathuba,
  • Takalani Rhodah Luhalima,
  • Seani Adrinah Mulondo,
  • Thivhulawi Malwela,
  • Azwidihwi Rose Tshililo,
  • Julia Langanani Mafumo,
  • Maria Sonto Maputle,
  • Mary Maluleke and
  • Mutshinyalo Lizzy Netshikweta
  • + 4 authors

1 March 2023

Background: Effective communication between health care professionals, admitted patients, and their families is crucial to improving the health care outcomes and patient satisfaction. Hence, barriers to effective communication cause a lot of confusio...

  • Article
  • Open Access
2 Citations
2,918 Views
16 Pages

Nurses’ Perceptions and Expectations of Patient Violence: Language Matters

  • Darcy Copeland,
  • Mary Potter,
  • Susan Tipton and
  • Debra Culter

Background: Patient violence is a serious occupational risk for nurses. Some professional rhetoric presents this risk as not part of nursing work, discounting widespread exposure. There is a disjunction between nurses’ experiences and the disco...

  • Article
  • Open Access
2 Citations
2,339 Views
14 Pages

Using Natural Language Processing and Social Media Data to Understand the Lived Experience of People with Fibromyalgia

  • Lucy Bell,
  • Beth Fordham,
  • Sehreen Mumtaz,
  • Reena Yaman,
  • Lisa Balistreri,
  • Ronald R. Butendieck and
  • Anushka Irani

11 December 2024

Background and Objectives: Fibromyalgia has many unmet needs relating to treatment, and the delivery of effective and evidence-based healthcare is lacking. We analyzed social media conversations to understand the patients’ perspectives on the l...

  • Article
  • Open Access
133 Views
18 Pages

21 January 2026

Objectives: This study aims to explore the facilitators and barriers in the process of using AI agents for disease management in older COPD patients. Methods: Based on the normalization process theory, a descriptive qualitative study was used to cond...

  • Article
  • Open Access
12 Citations
4,983 Views
15 Pages

16 March 2022

Most rare diseases are genetic in etiology and characterized by a ‘diagnostic odyssey’. Genomic advances have helped speed up the diagnosis for many rare disorders, opening new avenues for precision therapies. Little is known about patien...

  • Article
  • Open Access
20 Citations
4,090 Views
17 Pages

Consequences of Nurse Presenteeism in Switzerland and Portugal and Strategies to Minimize It: A Qualitative Study

  • Filipa Pereira,
  • Ana Querido,
  • Henk Verloo,
  • Marion Bieri and
  • Carlos Laranjeira

25 September 2022

Nurses exhibit higher rates of presenteeism than other professionals, with consequences for the quality of care and patient safety. However, nurses’ perceptions of these issues have been poorly explored. This study investigated the perceptions...

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