Next Article in Journal
Correction: Rachel Brown and Sheila Skeaff. Nutrition Society of New Zealand Annual Conference Held in Christchurch, New Zealand, 8–9 December 2016. Nutrients 2017, 9, 348
Next Article in Special Issue
Zinc in Infection and Inflammation
Previous Article in Journal
Erratum: Intake of Marine-Derived Omega-3 Polyunsaturated Fatty Acids and Mortality in Renal Transplant Recipients; Nutrients 2017, 9, 363
Previous Article in Special Issue
Nutritional Challenges in Duchenne Muscular Dystrophy

Microbiota and Probiotics in Health and HIV Infection

Unit of Immunodiagnostic and Molecular Pathology, Department of Medical, Oral and Biotechnological Sciences, University “G. d’Annunzio” Chieti-Pescara, 66100 Chieti, Italy
Author to whom correspondence should be addressed.
Nutrients 2017, 9(6), 615;
Received: 26 January 2017 / Revised: 8 June 2017 / Accepted: 12 June 2017 / Published: 16 June 2017
(This article belongs to the Special Issue Nutrients, Infectious and Inflammatory Diseases)
Microbiota play a key role in various body functions, as well as in physiological, metabolic, and immunological processes, through different mechanisms such as the regulation of the development and/or functions of different types of immune cells in the intestines. Evidence indicates that alteration in the gut microbiota can influence infectious and non-infectious diseases. Bacteria that reside on the mucosal surface or within the mucus layer interact with the host immune system, thus, a healthy gut microbiota is essential for the development of mucosal immunity. In patients with human immunodeficiency virus (HIV), including those who control their disease with antiretroviral drugs (ART), the gut microbiome is very different than the microbiome of those not infected with HIV. Recent data suggests that, for these patients, dysbiosis may lead to a breakdown in the gut’s immunologic activity, causing systemic bacteria diffusion and inflammation. Since in HIV-infected patients in this state, including those in ART therapy, the treatment of gastrointestinal tract disorders is frustrating, many studies are in progress to investigate the ability of probiotics to modulate epithelial barrier functions, microbiota composition, and microbial translocation. This mini-review analyzed the use of probiotics to prevent and attenuate several gastrointestinal manifestations and to improve gut-associated lymphoid tissue (GALT) immunity in HIV infection. View Full-Text
Keywords: microbiome; probiotics; dietary supplements; nutrition; HIV; inflammation microbiome; probiotics; dietary supplements; nutrition; HIV; inflammation
Show Figures

Figure 1

MDPI and ACS Style

D’Angelo, C.; Reale, M.; Costantini, E. Microbiota and Probiotics in Health and HIV Infection. Nutrients 2017, 9, 615.

AMA Style

D’Angelo C, Reale M, Costantini E. Microbiota and Probiotics in Health and HIV Infection. Nutrients. 2017; 9(6):615.

Chicago/Turabian Style

D’Angelo, Chiara, Marcella Reale, and Erica Costantini. 2017. "Microbiota and Probiotics in Health and HIV Infection" Nutrients 9, no. 6: 615.

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

Back to TopTop