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  • Article
  • Open Access
7 Citations
2,971 Views
12 Pages

The Extent and Nature of Functional Limitations According to the Health Assessment Questionnaire Disability Index in Patients with Rheumatoid Arthritis and Severe Functional Disability

  • Max M. H. Teuwen,
  • Maria A. T. van Wissen,
  • Wilfred F. Peter,
  • Dirkjan van Schaardenburg,
  • Cornelia H. M. van den Ende,
  • Maaike G. J. Gademan and
  • Salima F. E. van Weely

10 January 2024

Background: For a subgroup of people with rheumatoid arthritis (RA) and severe disability, insight into their limitations is crucial for adequate treatment. Aim: To describe the extent and nature of functional limitations in people with RA and severe...

  • Article
  • Open Access
14 Citations
4,620 Views
10 Pages

Association between Ambulatory Status and Functional Disability in Elderly People with Dementia

  • Hsun-Hua Lee,
  • Chien-Tai Hong,
  • Dean Wu,
  • Wen-Chou Chi,
  • Chia-Feng Yen,
  • Hua-Fang Liao,
  • Lung Chan and
  • Tsan-Hon Liou

Dementia is highly comorbid with gait disturbance, and both conditions negatively impact the ability of elderly people to conduct daily living activities. The ambulatory status of older adults with dementia may cause variable functional disability, w...

  • Article
  • Open Access
14 Citations
5,656 Views
10 Pages

Dementia is a common nonmotor condition among people with moderate or advanced Parkinson’s disease (PD). Undoubtedly, profound motor symptoms cause remarkable impairment in daily activities; however, dementia-related disabilities have not been...

  • Article
  • Open Access
1 Citations
2,104 Views
15 Pages

Folate may have beneficial effects on physical function through its antioxidant effect. Thus, we investigated the associations between serum folate and functional disability in older adults. Data from the National Health and Nutrition Examination Sur...

  • Article
  • Open Access
6 Citations
3,963 Views
15 Pages

Sarcoscore: A Novel Approach for Assessing Sarcopenia and Functional Disability in Older Adults

  • Yosuke Osuka,
  • Hunkyung Kim,
  • Hisashi Kawai,
  • Yu Taniguchi,
  • Yuri Yokoyama,
  • Satoshi Seino,
  • Shuichi Obuchi,
  • Akihiko Kitamura and
  • Shoji Shinkai

Sarcopenia is associated with instrumental activities of daily living (IADL) and basic activities of daily living (BADL) disabilities. We developed an index for assessing sarcopenia degree (sarcoscore) and compared it to the Asian Working Group for S...

  • Article
  • Open Access
14 Citations
3,405 Views
11 Pages

How Did People with Functional Disability Experience the First COVID-19 Lockdown? A Thematic Analysis of YouTube Comments

  • Karen A. E. Hall,
  • Blanca Deusdad,
  • Manuel D’Hers Del Pozo and
  • Ángel Martínez-Hernáez

People with functional disability endure barriers to health and other services and to full participation in social life. In the context of COVID-19, this discrimination has been intensified worldwide. We examine how the experience of COVID-19 lockdow...

  • Article
  • Open Access
2 Citations
2,241 Views
11 Pages

Functional Disability and Symptomatic Slow-Acting Drugs for Osteoarthritis in Adults with Periodontitis

  • Nik-Madihah Nik-Azis,
  • Nurulhuda Mohd,
  • Badiah Baharin,
  • Fazalina Mohd Fadzilah,
  • Nor Hazla Mohamed Haflah and
  • Mohd Shahrir Mohamed Said

Osteoarthritis (OA) patients have decreased functional ability and restricted access to healthcare facilities and are on a spectrum of medications. These can impact their oral health. This study aims to investigate the association between periodontal...

  • Article
  • Open Access
10 Citations
3,729 Views
15 Pages

Functional Disability in Adolescents with Chronic Pain: Comparing an Interdisciplinary Exposure Program to Usual Care

  • Carolien Dekker,
  • Mariëlle Goossens,
  • Bjorn Winkens,
  • Silvia Remerie,
  • Caroline Bastiaenen and
  • Jeanine Verbunt

11 December 2020

(1) Background: Chronic musculoskeletal pain (CMP) in adolescents can negatively affect physical, psychological, and social functioning, resulting in functional disability. This randomized controlled trial (RCT) aimed to evaluate the effectiveness of...

  • Article
  • Open Access
5 Citations
2,486 Views
10 Pages

Functional Mobility and Balance Confidence Measures Are Associated with Disability among Community-Dwelling Older Adults

  • Norah A. Alhwoaimel,
  • Mohammed M. Alshehri,
  • Ahmed S. Alhowimel,
  • Aqeel M. Alenazi and
  • Bader A. Alqahtani

22 September 2024

Background and Objectives: Our objectives were to examine the association between balance confidence, functional mobility measures, and the presence of disability in older adults in Saudi Arabia and to identify the optimal cutoff scores for these mea...

  • Article
  • Open Access
556 Views
18 Pages

23 December 2025

Background/Objectives: Cervical spondylosis is a cause of recurrent neck pain, disability, and poor quality of life (QoL). This study aimed to examine the relationships among pain intensity, neck disability, functional performance, body mass index, a...

  • Article
  • Open Access
20 Citations
6,764 Views
12 Pages

Subacromial Impingement Syndrome (SAIS) is a common shoulder condition characterized by pain and functional impairment. Proprioception, the sense of joint position and movement, is crucial in maintaining joint stability and coordinating movements. Th...

  • Article
  • Open Access
4 Citations
3,013 Views
12 Pages

Functional disability and physical frailty (PF) are debilitating geriatric conditions. Previous studies have suggested both perceived neighborhood social cohesion (PNSC) and PF can influence functional disability and may have an interactive effect to...

  • Article
  • Open Access
7 Citations
2,341 Views
20 Pages

Objectives: Gait kinematic and kinetic changes have been identified in older adults, highlighting the need to explore the principal age-related components and how these are associated with functional disability. This study aims to perform a factor an...

  • Article
  • Open Access
3,516 Views
10 Pages

Diet-Induced Changes in Functional Disability among People with Multiple Sclerosis: A Secondary Pooled Analysis of Two Randomized Controlled Pilot Trials

  • Allison R. Groux,
  • Elizabeth S. Walker,
  • Farnoosh Shemirani,
  • Jennifer E. Lee,
  • Amanda K. Irish,
  • Linda M. Rubenstein,
  • Linda G. Snetselaar,
  • Warren G. Darling,
  • Terry L. Wahls and
  • Tyler J. Titcomb

4 July 2024

Emerging evidence links dietary interventions to favorable multiple sclerosis (MS) outcomes; however, evidence for the efficacy of dietary interventions on functional disability remains sparse. Data from two 12-week, randomized, controlled pilot tria...

  • Article
  • Open Access
1 Citations
1,403 Views
14 Pages

Emotional Status in Relation to Metacognitive Self-Awareness and Level of Functional Disability Following Acquired Brain Injury

  • Valentina Bandiera,
  • Dolores Villalobos,
  • Alberto Costa,
  • Gaia Galluzzi,
  • Alessia Quinzi,
  • Arianna D’Aprile and
  • Umberto Bivona

Background/Objectives: Impairment in self-awareness (ISA) is one of the common consequences of an acquired brain injury (ABI) and is associated with anosodiaphoria. Collectively, these co-occurring neuropsychological disorders pose significant obstac...

  • Article
  • Open Access
6 Citations
4,521 Views
20 Pages

11 October 2021

Functional disability in people with dementia is associated with placement in long-term care facilities, feelings of depression and caregiver burden. As there is currently no cure for dementia, more attention is needed for personalised support for pe...

  • Article
  • Open Access
18 Citations
3,151 Views
12 Pages

People with intellectual disability or psychiatric disorders and cognitive dysfunctions may need assistive technology to maintain and improve their levels of functioning and independence. This study assessed a smartphone-based system to remind the us...

  • Article
  • Open Access
29 Citations
5,409 Views
13 Pages

Objective: The aim of this study is to assess the risk factors for incident functional disability among long-term evacuees of Iitate village after Great East Japan Earthquake and nuclear disaster (GEJE). We also investigated the effectiveness of exer...

  • Article
  • Open Access
927 Views
13 Pages

Hospital-Acquired Disability as a Predictor of Functional Decline in ICU Survivors: A Multicenter Prospective Cohort Study in Japan

  • Yuki Iida,
  • Shinichi Watanabe,
  • Yorihide Yanagita,
  • Ayato Shinohara,
  • Tomoyuki Morisawa,
  • Kengo Obata,
  • Ryo Kozu,
  • Shigeaki Inoue,
  • Osamu Nishida and
  • from the RELIFE Network

18 November 2025

Background: Hospital-acquired disability (HAD), defined as a decline in activities of daily living (ADL) during hospitalization, is a significant component of post-intensive care syndrome (PICS) and may influence long-term outcomes in critically ill...

  • Article
  • Open Access
7 Citations
4,648 Views
12 Pages

Large-Scale Assessment of Function and Disability in Patients with Parkinson’s Disease Using the Functioning Disability Evaluation Scale-Adult Version

  • Tzu-Herng Hsu,
  • Tsan-Hon Liou,
  • Kuei-Ru Chou,
  • Wen-Chou Chi,
  • Chia-Feng Yen,
  • Hua-Fang Liao and
  • Ing-Jy Tseng

This study assesses the functioning and disability related to Parkinson’s disease using the Functioning Disability Evaluation Scale-Adult Version (FUNDES-Adult), based on the World Health Organization Disability Assessment Schedule 2.0 (WHODAS...

  • Case Report
  • Open Access
12 Citations
3,516 Views
8 Pages

18 April 2019

Physical activity (PA) interventions can improve physical functioning, treatment-related symptoms and quality of life (QoL) in cancer survivors. Most investigations have been conducted in breast cancer survivors, while studies on PA interventions in...

  • Article
  • Open Access
8 Citations
13,990 Views
16 Pages

Efficacy of Core-Strengthening and Intensive Dynamic Back Exercises on Pain, Core Muscle Endurance, and Functional Disability in Patients with Chronic Non-Specific Low Back Pain: A Randomized Comparative Study

  • Raee Saeed Alqhtani,
  • Hashim Ahmed,
  • Hussain Saleh H. Ghulam,
  • Abdullah Mohammed Alyami,
  • Yousef Hamad Hassan Al Sharyah,
  • Reyaz Ahmed,
  • Ashfaque Khan and
  • Abdur Raheem Khan

15 January 2024

Background: Chronic back pains are progressively disabling working individuals, including 60–80% of the general population, for which their diagnosis is challenging to healthcare workers worldwide, thereby becoming a burden to nations. Purpose:...

  • Communication
  • Open Access
17 Citations
6,711 Views
8 Pages

Disability organisations have not been engaged in the debate about the International Classification of Functioning, Disability and Health (ICF) in Sweden. We wanted to know representatives’ attitudes about the ICF. The aim of the study was to elucid...

  • Article
  • Open Access
36 Citations
9,255 Views
12 Pages

Functioning and Disability Analysis of Patients with Traumatic Brain Injury and Spinal Cord Injury by Using the World Health Organization Disability Assessment Schedule 2.0

  • Chia-Ying Kuo,
  • Tsan-Hon Liou,
  • Kwang-Hwa Chang,
  • Wen-Chou Chi,
  • Reuben Escorpizo,
  • Chia-Feng Yen,
  • Hua-Fang Liao,
  • Hung-Yi Chiou,
  • Wen-Ta Chiu and
  • Jo-Ting Tsai

The purpose of this study is to compare traumatic brain injuries (TBI) and spinal cord injuries (SCI) patients’ function and disability by using the World Health Organization Disability Assessment Schedule 2.0 (WHODAS 2.0); and to clarify the factors...

  • Article
  • Open Access
8 Citations
3,324 Views
13 Pages

The Association between Executive Function and Performing Instrumental Daily Activities in People with Intellectual Disabilities

  • Beatriz García-Pintor,
  • Francisco Manuel Morales-Rodríguez and
  • José Manuel Pérez-Mármol

23 August 2023

Institutionalized individuals with intellectual disabilities have few opportunities to participate in instrumental activities of daily living (IADLs), which probably affects higher cognitive functions, or vice versa. The objectives of this study were...

  • Article
  • Open Access
2 Citations
828 Views
15 Pages

24 September 2025

Background: Adults with developmental disabilities often experience accelerated aging, but the magnitude of this phenomenon is not well quantified. This study aimed to measure the disparity in functional ability and chronic illness prevalence between...

  • Article
  • Open Access
3 Citations
3,710 Views
21 Pages

Executive Functioning in Different Types of Reading Disabilities

  • Irene Cadime,
  • Bruna Rodrigues,
  • Iolanda Ribeiro and
  • María Teresa Martín-Aragoneses

Students with reading disabilities form a heterogeneous group: some struggle with accurate and fast reading (dysfluent readers), others with comprehension (poor comprehenders), and some face challenges in both areas (poor readers). Research has indic...

  • Article
  • Open Access
6 Citations
8,596 Views
14 Pages

A New Criterion for Fluoroquinolone-Associated Disability Diagnosis: Functional Gastrointestinal Disorders

  • Deanna N. Cannizzaro,
  • Lydia F. Naughton,
  • Maya Z. Freeman,
  • Linda Martin,
  • Charles L. Bennett and
  • Cecilia Bove

16 December 2021

Background and Objectives: Fluoroquinolones (FQs) are a broad-spectrum class of antibiotics routinely prescribed for common bacterial infections despite recent recommendations to use them only for life-threatening cases. In addition to their antimicr...

  • Article
  • Open Access
387 Views
19 Pages

Cardiovascular Functioning Features in Individuals with Connective Tissue Dysplasia Engaged in Sports for the Disabled

  • Kamiliia Vinokurova,
  • Anna Zakharova,
  • Yulia Zinovieva,
  • Arseniy Epifanov,
  • Anna Galdobina,
  • Ekaterina Sharkova and
  • Felix Blyakhman

5 February 2026

Objectives: Connective tissue dysplasia (CTD) is associated with disorders of collagen synthesis and is widely spread among the healthy population and people with disabilities. In the heart, primarily in the left ventricle (LV), CTD manifests itself...

  • Article
  • Open Access
10 Citations
5,590 Views
15 Pages

16 October 2024

The International Classification of Functioning, Disability, and Health (ICF) offers a comprehensive bio-psycho-social model for evaluating the multifaceted needs of individuals with disabilities. While its adoption in healthcare settings is widespre...

  • Review
  • Open Access
8 Citations
7,606 Views
18 Pages

Functioning, as described in the International Classification of Functioning, Disability and Health (ICF), increasingly raises interest in the world of child rehabilitation, especially because its application empowers patients and parents by not putt...

  • Article
  • Open Access
7 Citations
2,905 Views
20 Pages

Thyroid Function and Metabolic Syndrome in Children and Adolescents with Neuromotor Disability

  • Valeria Calcaterra,
  • Giacomo Biganzoli,
  • Simona Ferraro,
  • Alessandra Mari,
  • Anna Mandelli,
  • Valentina Fabiano,
  • Patrizia Carlucci,
  • Gloria Pelizzo,
  • Elena Zoia and
  • Gianvincenzo Zuccotti
  • + 4 authors

6 October 2022

Thyroid function plays a crucial role in nervous system integrity and metabolic homeostasis. We evaluated the pattern of TSH, FT4 and FT3 release in children with neuromotor impairment (NI) in relationship with metabolic syndrome (MS). We enrolled 55...

  • Article
  • Open Access
13 Citations
5,103 Views
16 Pages

Background: Adults with intellectual disability have limited executive function—which includes working memory, cognitive flexibility, and inhibitory control subcomponents—making their ability to live independently challenging. The present...

  • Article
  • Open Access
6 Citations
2,980 Views
14 Pages

Developmental disability is likely to be lifelong in nature and to result in substantial activity and societal participation limitations. The performance of individuals is related to the environment, supports, and urbanization of living cities. Most...

  • Article
  • Open Access
7 Citations
3,953 Views
20 Pages

12 June 2023

Background: People with mobility-related disabilities (MRDs) experience many personal and environmental barriers to engagement in community-based exercise programs. We explored the experiences of adults with MRD who currently participate in high-inte...

  • Article
  • Open Access
6 Citations
3,825 Views
13 Pages

Assessing the Functional Status of Patients with Chronic Pain—Cross Cultural Adaptation and Psychometric Properties of the Serbian Version of the Pain Disability Questionnaire

  • Aleksandar Knežević,
  • Petar Čolović,
  • Milica Jeremić-Knežević,
  • Čila Demeši-Drljan,
  • Dušica Simić-Panić and
  • Randy Neblett

The Pain Disability Questionnaire (PDQ) has established itself as a leading patient-reported outcome measure for assessing both mental and physical components of pain-related disability. The current study aimed to translate the PDQ into Serbian and v...

  • Feature Paper
  • Article
  • Open Access
2 Citations
2,248 Views
11 Pages

11 September 2021

The purpose of this study was to develop the Korean version of the Late-Life Function and Disability Instrument (K-LLFDI) and verify its reliability and validity. Fifty community-dwelling older adults aged 65 years and above with independent mobility...

  • Article
  • Open Access
12 Citations
6,789 Views
24 Pages

Disorders of consciousness are neurological conditions associated with low levels of functioning which pose a serious challenge to public health systems. The current study aimed to examine longitudinal changes in functioning in patients with disorder...

  • Review
  • Open Access
272 Views
22 Pages

28 January 2026

Background: Persistent pain following orthopaedic trauma is common, often disproportionate to structural healing, and increasingly interpreted as reflecting centrally mediated pain mechanisms. However, the mechanisms, clinical features, diagnostic ap...

  • Article
  • Open Access
1 Citations
4,568 Views
10 Pages

16 November 2016

Limited data exist on the validity of the Late-Life Function and Disability (LLFD) instrument in cancer survivors. We examined the construct validity of the abbreviated LLFD instrument in a sample of African-American breast cancer survivors. African...

  • Article
  • Open Access
9 Citations
5,422 Views
8 Pages

Applying the WHO International Classification of Functioning, Disability and Health in Nursing Assessment of Population Health

  • Juan Gómez-Salgado,
  • Lia Jacobsohn,
  • Fátima Frade,
  • Macarena Romero-Martin and
  • Carlos Ruiz-Frutos

Classification systems constitute an important contribution to nursing practice, as they provide standardized frameworks for communication between nurses and other healthcare professionals. International Classification of Functioning, Disability and...

  • Article
  • Open Access
1,174 Views
18 Pages

Functional limitations that compromise preventive healthcare service utilization by people with disabilities in Japan are unelucidated. Secondary data from the Comprehensive Survey of Living Conditions (CSLC) in 2022 on the functional limitations def...

  • Article
  • Open Access
6 Citations
3,562 Views
13 Pages

Anthropometric Indicators of the Cardiometabolic Risk, Muscle Strength, and Functional Capacity of Schoolchildren with Intellectual Disabilities during Lockdown in Chile

  • Claudio Farías-Valenzuela,
  • Gerson Ferrari,
  • Sebastián Espoz-Lazo,
  • Paloma Ferrero-Hernández,
  • Emilio Jofré-Saldia,
  • Sebastián Álvarez-Arangua,
  • Carlos Poblete-Aro,
  • Andrés Godoy-Cumillaf,
  • Cristian Cofre-Bolados and
  • Pedro Valdivia-Moral

29 August 2022

Lockdown due to the COVID-19 pandemic has negatively impacted the social, psychological, and physical well-being of the world population. In the case of people with intellectual disabilities, the impact of lockdown on their physical condition and fun...

  • Article
  • Open Access
11 Citations
3,491 Views
14 Pages

The purpose of this study was to investigate the relationship between cognitive function and depressive symptoms among Chinese adults aged 40 years and above, as well as the series of multiple mediating effects of Instrument Activities of Daily Livin...

  • Article
  • Open Access
24 Citations
8,046 Views
13 Pages

Eight Weeks of Inspiratory Muscle Training Improves Pulmonary Function in Disabled Swimmers—A Randomized Trial

  • Paulina Okrzymowska,
  • Monika Kurzaj,
  • Wojciech Seidel and
  • Krystyna Rożek-Piechura

Background: According to the literature, inspiratory muscle fatigue may increase after swimming training (ST). This study aimed to examine the efficacy of 8-week inspiratory muscular training (IMT) in disabled swimmers, combined with standard sports...

  • Article
  • Open Access
449 Views
20 Pages

High-Intensity Functional Training for Older Adults with Mobility Disabilities: A Feasibility Pilot Study

  • Lyndsie M. Koon,
  • Joseph E. Donnelly,
  • Jacob J. Sosnoff,
  • Abbas Tabatabaei,
  • Joseph R. Sherman,
  • Anna M. Rice,
  • Morgan Means,
  • Reed Handlery and
  • Kaci Handlery

30 January 2026

Background/Objectives: There is limited empirical evidence on the feasibility of inclusive, community-based exercise programs for older adults with long-term mobility disabilities. This pilot study investigated the feasibility and preliminary effecti...

  • Article
  • Open Access
67 Citations
15,440 Views
19 Pages

Implementation of the International Classification of Functioning, Disability, and Health (ICF) Core Sets for Children and Youth with Cerebral Palsy: Global Initiatives Promoting Optimal Functioning

  • Verónica Schiariti,
  • Egmar Longo,
  • Alexander Shoshmin,
  • Ludmila Kozhushko,
  • Yanina Besstrashnova,
  • Maria Król,
  • Taynah Neri Correia Campos,
  • Haryelle Náryma Confessor Ferreira,
  • Cláudia Verissimo and
  • Sandra Amado
  • + 2 authors

Background: The International Classification of Functioning, Disability, and Health (ICF) Core Sets for children and youth with cerebral palsy (CP) offer service providers and stakeholders a specific framework to explore functioning and disability fo...

  • Article
  • Open Access
6 Citations
3,950 Views
13 Pages

Disability disaggregation of Fiji’s Education Management Information System (FEMIS) is required to determine eligibility for inclusive education grants. Data from the UNICEF/Washington Group Child Functioning Module (CFM) alone is not accurate enough...

  • Article
  • Open Access
2 Citations
2,749 Views
24 Pages

22 January 2025

Background and Objectives: Recent research has focused on exploring the relationships between various factors associated with headaches and understanding their impact on individuals’ psychological states. Utilizing statistical methods and machi...

  • Article
  • Open Access
3 Citations
4,841 Views
18 Pages

Despite their separate research traditions, intelligence and executive functioning (EF) are both theoretically and empirically closely related to each other. Based on a subsample of 8- to 20-year-olds of the standardization and validation sample (N =...

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