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482 Results Found

  • Article
  • Open Access
1,238 Views
18 Pages

Exploration of Appetite Regulation in Yangtze Sturgeon (Acipenser dabryanus) During Weaning

  • Bin Wang,
  • Ni Tang,
  • Shuhuang Chen,
  • Xin Zhang,
  • Defang Chen,
  • Zhiqiong Li and
  • Bo Zhou

Yangtze sturgeon is an endangered fish species. After weaning, some Yangtze sturgeon fry refuse to consume any food, which causes a low survival rate during the artificial breeding period. This study showed that the body length and body weight of fai...

  • Article
  • Open Access
12 Citations
10,185 Views
12 Pages

Late, but Not Early, Night Sleep Loss Compromises Neuroendocrine Appetite Regulation and the Desire for Food

  • Svenja Meyhöfer,
  • Rodrigo Chamorro,
  • Manfred Hallschmid,
  • Denisa Spyra,
  • Nelli Klinsmann,
  • Bernd Schultes,
  • Hendrik Lehnert,
  • Sebastian M. Meyhöfer and
  • Britta Wilms

23 April 2023

Objective: There is evidence that reduced sleep duration increases hunger, appetite, and food intake, leading to metabolic diseases, such as type 2 diabetes and obesity. However, the impact of sleep timing, irrespective of its duration and on the reg...

  • Article
  • Open Access
10 Citations
4,177 Views
12 Pages

Age-Dependent Honey Bee Appetite Regulation Is Mediated by Trehalose and Octopamine Baseline Levels

  • İrem Akülkü,
  • Saleh Ghanem,
  • Elif Filiztekin,
  • Guntima Suwannapong and
  • Christopher Mayack

24 September 2021

There are multiple feedback mechanisms involved in appetite regulation, which is an integral part of maintaining energetic homeostasis. Older forager honey bees, in comparison to newly emerged bees and nurse bees, are known to have highly fluctuating...

  • Systematic Review
  • Open Access
3 Citations
12,410 Views
16 Pages

Effects of Chewing Gum on Satiety, Appetite Regulation, Energy Intake, and Weight Loss: A Systematic Review

  • Claudia Jiménez-ten Hoevel,
  • Elisabet Llauradó,
  • Rosa M. Valls,
  • Maria Besora-Moreno,
  • Judit Queral,
  • Rosa Solà and
  • Anna Pedret

25 January 2025

Background: New approaches for the management of obesity, a worldwide problem and a major determinant of disability and mortality, are needed. Mastication influences appetite and satiety mechanisms via actual food or sham feeding. However, the effect...

  • Review
  • Open Access
2,926 Views
18 Pages

12 August 2025

Background and Objectives: Ghrelin plays key roles in appetite regulation, involving both homeostatic and hedonic pathways. In obesity, its metabolism is affected by alterations in neural and hormonal responses. Liver-Enriched Antimicrobial Peptide 2...

  • Review
  • Open Access
70 Citations
15,724 Views
32 Pages

The hypothalamic peptide oxytocin and its receptor are involved in a range of physiological processes, including parturition, lactation, cell growth, wound healing, and social behavior. More recently, increasing evidence has established the effects o...

  • Article
  • Open Access
4 Citations
3,568 Views
10 Pages

Natural Appetite Control: Consumer Perception of Food-Based Appetite Regulating Aromas

  • Jacek Łyczko,
  • Michaela Godyla-Jabłoński,
  • Natalia Pachura,
  • Kinga Adamenko,
  • Marta Klemens and
  • Antoni Szumny

30 June 2023

According to the WHO, the number of overweight people (BMI ≥ 25) and obese people (BMI ≥ 30) is constantly growing. On the other hand, the number of elderly people (≥60 years old) in 2020 reached 1.4 billion worldwide. Both mentioned groups...

  • Article
  • Open Access
1 Citations
1,711 Views
14 Pages

Characterization of Feeding Behaviors, Appetite Regulation and Growth Performance of All-Female (cyp17a1+/−;XX Genotype) Common Carp (Cyprinus carpio)

  • Xuehui Li,
  • Qingqing Zou,
  • Xuebo Liu,
  • Qiyong Lou,
  • Xia Jin,
  • Jiangyan He,
  • Zhan Yin,
  • Gang Zhai,
  • Ming Duan and
  • Guanghui Chen

21 November 2024

Genome editing has the potential to improve growth and traits of aquatic animals. Assessment of the feeding habits of the genetically modified farmed fish is necessary, as this is closely related to the assessment of their growth performance, which i...

  • Review
  • Open Access
57 Citations
27,590 Views
12 Pages

Sleep Deprivation and Central Appetite Regulation

  • Shuailing Liu,
  • Xiya Wang,
  • Qian Zheng,
  • Lanyue Gao and
  • Qi Sun

7 December 2022

Research shows that reduced sleep duration is related to an increased risk of obesity. The relationship between sleep deprivation and obesity, type 2 diabetes, and other chronic diseases may be related to the imbalance of appetite regulation. To comp...

  • Article
  • Open Access
1,459 Views
14 Pages

Effects of Feeding Frequency on Liver Transcriptome: Unveiling Appetite-Regulating Peptides in Mexican Pike Silverside (Chirostoma estor)

  • Mitzi Ernestina Juárez-Gutiérrez,
  • Carlos Cristian Martínez-Chávez,
  • Claudia Yaneth Godoy-Figueroa,
  • Verónica Jiménez-Jacinto,
  • María Gisela Ríos-Durán,
  • Carlos Antonio Martínez-Palacios and
  • Pamela Navarrete-Ramírez

30 September 2024

The Mexican pike silverside (Chirostoma estor) is a zooplanktivorous, agastric short-intestined species, and it has been found that increased-frequency feeding (twelve feedings a day) improved feed efficiency and promoted growth by 70%. This work det...

  • Review
  • Open Access
25 Citations
11,783 Views
13 Pages

Rethinking the Role of Orexin in the Regulation of REM Sleep and Appetite

  • Maria P. Mogavero,
  • Justyna Godos,
  • Giuseppe Grosso,
  • Filippo Caraci and
  • Raffaele Ferri

22 August 2023

Orexin plays a significant role in the modulation of REM sleep, as well as in the regulation of appetite and feeding. This review explores, first, the current evidence on the role of orexin in the modulation of sleep and wakefulness and highlights th...

  • Systematic Review
  • Open Access
1 Citations
8,995 Views
23 Pages

11 April 2024

This systematic review aims to analyze the effects of acute and chronic exercise on appetite and appetite regulation in patients with abnormal glycemic control. PubMed, Web of Science, and the Cochrane Central Register of Controlled Trials were searc...

  • Review
  • Open Access
30 Citations
4,743 Views
14 Pages

26 September 2021

Eating disorders and obesity are important health problems with a widespread global epidemic. Adiponectin (AdipoQ), the most abundant adipokine in the plasma, plays important roles in the regulation of energy homeostasis, glucose metabolism and lipid...

  • Article
  • Open Access
14 Citations
3,892 Views
14 Pages

Orosensory Perception of Fat/Sweet Stimuli and Appetite-Regulating Peptides before and after Sleeve Gastrectomy or Gastric Bypass in Adult Women with Obesity

  • Arnaud Bernard,
  • Johanne Le Beyec-Le Bihan,
  • Loredana Radoi,
  • Muriel Coupaye,
  • Ouidad Sami,
  • Nathalie Casanova,
  • Cédric Le May,
  • Xavier Collet,
  • Pascaline Delaby and
  • Cindy Le Bourgot
  • + 2 authors

8 March 2021

The aim of this study was to explore the impact of bariatric surgery on fat and sweet taste perceptions and to determine the possible correlations with gut appetite-regulating peptides and subjective food sensations. Women suffering from severe obesi...

  • Article
  • Open Access
1 Citations
3,474 Views
16 Pages

Brain Perception of Different Oils on Appetite Regulation: An Anorectic Gene Expression Pattern in the Hypothalamus Dependent on the Vagus Nerve

  • Gele de Carvalho Araújo Lopes,
  • Brenda Caroline Rodrigues Miranda,
  • João Orlando Piauilino Ferreira Lima,
  • Jorddam Almondes Martins,
  • Athanara Alves de Sousa,
  • Taline Alves Nobre,
  • Juliana Soares Severo,
  • Tiago Eugênio Oliveira da Silva,
  • Milessa da Silva Afonso and
  • Joana Darc Carola Correia Lima
  • + 7 authors

24 July 2024

(1) Background: We examined the effect of the acute administration of olive oil (EVOO), linseed oil (GLO), soybean oil (SO), and palm oil (PO) on gastric motility and appetite in rats. (2) Methods: We assessed food intake, gastric retention (GR), and...

  • Review
  • Open Access
133 Citations
31,695 Views
39 Pages

From Belly to Brain: Targeting the Ghrelin Receptor in Appetite and Food Intake Regulation

  • Ken Howick,
  • Brendan T. Griffin,
  • John F. Cryan and
  • Harriët Schellekens

Ghrelin is the only known peripherally-derived orexigenic hormone, increasing appetite and subsequent food intake. The ghrelinergic system has therefore received considerable attention as a therapeutic target to reduce appetite in obesity as well as...

  • Article
  • Open Access
1 Citations
4,873 Views
12 Pages

20 September 2019

Previous studies have shown that habitual physical activity improves postprandial appetite regulation. We evaluated the direct association between physical activity level (PAL) and postprandial appetite regulation, and the effect of day-to-day variat...

  • Feature Paper
  • Review
  • Open Access
95 Citations
25,460 Views
18 Pages

20 July 2021

The worldwide prevalence of metabolic diseases such as obesity, metabolic syndrome and type 2 diabetes shows an upward trend in recent decades. A characteristic feature of these diseases is hyperglycemia which can be associated with hyperphagia. Abso...

  • Feature Paper
  • Review
  • Open Access
15 Citations
8,717 Views
23 Pages

Feeding and nutrition follow the growth trajectory of the course of life. The profound physiological changes that human body experiences during ageing affect separate aspects of food intake, from tastant perception to satiety. Concurrent morbidities,...

  • Article
  • Open Access
24 Citations
4,235 Views
17 Pages

30 October 2020

Pediatric obesity is a serious public health challenge and there is a need for research that synthesizes the various linkages among the child and parental factors that contribute to pediatric overweight and obesity. The main objective of this study w...

  • Review
  • Open Access
8 Citations
9,685 Views
23 Pages

20 August 2020

Evidence synthesizing the effects of acute body water losses on various markers of glycemic regulation, appetite, metabolism, and stress is lacking. Thus, the purpose of this review was to summarize the response of various hormonal changes involved i...

  • Review
  • Open Access
37 Citations
11,362 Views
19 Pages

The Mechanism of the Gut-Brain Axis in Regulating Food Intake

  • Shouren Li,
  • Mengqi Liu,
  • Shixi Cao,
  • Boshuai Liu,
  • Defeng Li,
  • Zhichang Wang,
  • Hao Sun,
  • Yalei Cui and
  • Yinghua Shi

25 August 2023

With the increasing prevalence of energy metabolism disorders such as diabetes, cardiovascular disease, obesity, and anorexia, the regulation of feeding has become the focus of global attention. The gastrointestinal tract is not only the site of food...

  • Article
  • Open Access
12 Citations
7,812 Views
12 Pages

Post-Exercise Whole Body Cryotherapy (−140 °C) Increases Energy Intake in Athletes

  • Chihiro Kojima,
  • Nobukazu Kasai,
  • Chika Kondo,
  • Kumiko Ebi and
  • Kazushige Goto

12 July 2018

PURPOSE: The purpose of the present study was to investigate the effect of whole-body cryotherapy (WBC) treatment after exercise on appetite regulation and energy intake. METHODS: Twelve male athletes participated in two trials on different days. In...

  • Review
  • Open Access
6 Citations
4,416 Views
20 Pages

Targeting the Gut in Obesity: Signals from the Inner Surface

  • Natalia Petersen,
  • Thomas U. Greiner,
  • Lola Torz,
  • Angie Bookout,
  • Marina Kjærgaard Gerstenberg,
  • Carlos M. Castorena and
  • Rune Ehrenreich Kuhre

5 January 2022

Obesity is caused by prolonged energy surplus. Current anti-obesity medications are mostly centralized around the energy input part of the energy balance equation by increasing satiety and reducing appetite. Our gastrointestinal tract is a key organ...

  • Article
  • Open Access
48 Citations
7,103 Views
14 Pages

Goldfish Leptin-AI and Leptin-AII: Function and Central Mechanism in Feeding Control

  • Ai-Fen Yan,
  • Ting Chen,
  • Shuang Chen,
  • Chun-Hua Ren,
  • Chao-Qun Hu,
  • Yi-Ming Cai,
  • Fang Liu and
  • Dong-Sheng Tang

In mammals, leptin is a peripheral satiety factor that inhibits feeding by regulating a variety of appetite-related hormones in the brain. However, most of the previous studies examining leptin in fish feeding were performed with mammalian leptins, w...

  • Review
  • Open Access
8 Citations
3,708 Views
13 Pages

Anorexigenic Effects of Intermittent Hypoxia on the Gut—Brain Axis in Sleep Apnea Syndrome

  • Ryogo Shobatake,
  • Hiroyo Ota,
  • Nobuyuki Takahashi,
  • Satoshi Ueno,
  • Kazuma Sugie and
  • Shin Takasawa

29 December 2021

Sleep apnea syndrome (SAS) is a breathing disorder characterized by recurrent episodes of upper-airway collapse, resulting in intermittent hypoxia (IH) during sleep. Experimental studies with animals and cellular models have indicated that IH leads t...

  • Review
  • Open Access
18 Citations
6,452 Views
17 Pages

Mechanisms Involved in the Link between Depression, Antidepressant Treatment, and Associated Weight Change

  • Tomas Kukucka,
  • Nikola Ferencova,
  • Zuzana Visnovcova,
  • Igor Ondrejka,
  • Igor Hrtanek,
  • Veronika Kovacova,
  • Andrea Macejova,
  • Zuzana Mlyncekova and
  • Ingrid Tonhajzerova

Major depressive disorder is a severe mood disorder associated with a marked decrease in quality of life and social functioning, accompanied by a risk of suicidal behavior. Therefore, seeking out and adhering to effective treatment is of great person...

  • Review
  • Open Access
32 Citations
12,559 Views
19 Pages

The Influence of Ketone Bodies on Circadian Processes Regarding Appetite, Sleep and Hormone Release: A Systematic Review of the Literature

  • Davide Masi,
  • Maria Elena Spoltore,
  • Rebecca Rossetti,
  • Mikiko Watanabe,
  • Rossella Tozzi,
  • Alessandra Caputi,
  • Renata Risi,
  • Angela Balena,
  • Orietta Gandini and
  • Stefania Mariani
  • + 3 authors

28 March 2022

Chrononutrition is an emerging branch of chronobiology focusing on the profound interactions between biological rhythms and metabolism. This framework suggests that, just like all biological processes, even nutrition follows a circadian pattern. Rece...

  • Article
  • Open Access
13 Citations
7,396 Views
17 Pages

26 September 2018

Despite the abundance of plant-derived fats in our diet, their effects on appetite, and metabolic markers, remain unclear. This single-blinded 3-way cross-over pilot study aimed to investigate the ability of the two most abundant dietary plant-derive...

  • Review
  • Open Access
6 Citations
7,924 Views
33 Pages

27 February 2024

Obesity remains a common metabolic disorder and a threat to health as it is associated with numerous complications. Lifestyle modifications and caloric restriction can achieve limited weight loss. Bariatric surgery is an effective way of achieving su...

  • Review
  • Open Access
22 Citations
10,934 Views
22 Pages

Myokines in Appetite Control and Energy Balance

  • Andrew Grannell,
  • Alexander Kokkinos and
  • Carel W. le Roux

30 January 2022

Efficacy of obesity treatments varies between individuals, highlighting the presence of responders and non-responders. Whilst exercise alone or exercise combined with diet leads to underwhelming weight loss for most, there exist super responders losi...

  • Article
  • Open Access
14 Citations
13,531 Views
14 Pages

23 June 2021

Global protein consumption has been increasing for decades due to changes in demographics and consumer shifts towards higher protein intake to gain health benefits in performance nutrition and appetite regulation. Plant-derived proteins may provide a...

  • Review
  • Open Access
2 Citations
3,282 Views
25 Pages

Neurobiological and Microbiota Alterations After Bariatric Surgery: Implications for Hunger, Appetite, Taste, and Long-Term Metabolic Health

  • Sebastián Chapela,
  • Ludwig Alvarez-Córdova,
  • Andres Martinuzzi,
  • Rosario Suarez,
  • Victoria Gonzalez,
  • Ezequiel Manrique,
  • Janeth Castaño,
  • Gianluca Rossetti,
  • Luigi Cobellis and
  • Vincenzo Pilone
  • + 2 authors

Bariatric surgery (BS) is an effective intervention for obesity, inducing significant neurobiological and gut microbiota changes that influence hunger, appetite, taste perception, and long-term metabolic health. This narrative review examines these a...

  • Article
  • Open Access
13 Citations
4,559 Views
14 Pages

Effect of Obesity on the Expression of Nutrient Receptors and Satiety Hormones in the Human Colon

  • Lucas Baumard,
  • Zsa Zsa R. M. Weerts,
  • Ad A. M. Masclee,
  • Daniel Keszthelyi,
  • Adina T. Michael-Titus and
  • Madusha Peiris

13 April 2021

Background: Receptors located on enteroendocrine cells (EECs) of the colon can detect nutrients in the lumen. These receptors regulate appetite through a variety of mechanisms, including hormonal and neuronal signals. We assessed the effect of obesit...

  • Commentary
  • Open Access
14 Citations
7,743 Views
7 Pages

Physical Exercise and Appetite Regulation: New Insights

  • Lorenzo Caruso,
  • Enrico Zauli and
  • Mauro Vaccarezza

27 July 2023

Physical exercise is considered an important physiological intervention able to prevent cardiovascular diseases, obesity, and obesity-related cardiometabolic imbalance. Nevertheless, basic molecular mechanisms that govern the metabolic benefits of ph...

  • Article
  • Open Access
13 Citations
5,108 Views
16 Pages

Oat Polar Lipids Improve Cardiometabolic-Related Markers after Breakfast and a Subsequent Standardized Lunch: A Randomized Crossover Study in Healthy Young Adults

  • Mohammad Mukul Hossain,
  • Juscelino Tovar,
  • Lieselotte Cloetens,
  • Maria T. Soria Florido,
  • Karin Petersson,
  • Frederic Prothon and
  • Anne Nilsson

18 March 2021

It has been suggested that intake of polar lipids may beneficially modulate various metabolic variables. The purpose of this study was to evaluate the effect of oat polar lipids on postprandial and second meal glycemic regulation, blood lipids, gastr...

  • Article
  • Open Access
3 Citations
3,440 Views
17 Pages

Effects of Wheat Biscuits Enriched with Plant Proteins Incorporated into an Energy-Restricted Dietary Plan on Postprandial Metabolic Responses of Women with Overweight/Obesity

  • Maria-Christina Kanata,
  • Amalia E. Yanni,
  • Chrysi Koliaki,
  • Irene Pateras,
  • Ioanna A. Anastasiou,
  • Alexander Kokkinos and
  • Vaios T. Karathanos

20 April 2024

This study investigates the effect of daily consumption of wheat biscuits enriched with plant proteins in postprandial metabolic responses of women with overweight/obesity who follow an energy-restricted diet. Thirty apparently healthy women particip...

  • Article
  • Open Access
23 Citations
7,024 Views
17 Pages

Effects of L-Phenylalanine on Energy Intake and Glycaemia—Impacts on Appetite Perceptions, Gastrointestinal Hormones and Gastric Emptying in Healthy Males

  • Penelope C. E. Fitzgerald,
  • Benoit Manoliu,
  • Benjamin Herbillon,
  • Robert E. Steinert,
  • Michael Horowitz and
  • Christine Feinle-Bisset

16 June 2020

In humans, phenylalanine stimulates plasma cholecystokinin (CCK) and pyloric pressures, both of which are important in the regulation of energy intake and gastric emptying. Gastric emptying is a key determinant of postprandial blood glucose. We evalu...

  • Article
  • Open Access
45 Citations
5,220 Views
15 Pages

Appetite Regulation, Growth Performances and Fish Quality Are Modulated by Alternative Dietary Protein Ingredients in Gilthead Sea Bream (Sparus aurata) Culture

  • Lina Fernanda Pulido-Rodriguez,
  • Gloriana Cardinaletti,
  • Giulia Secci,
  • Basilio Randazzo,
  • Leonardo Bruni,
  • Roberto Cerri,
  • Ike Olivotto,
  • Emilio Tibaldi and
  • Giuliana Parisi

28 June 2021

By answering the need for increasing sustainability in aquaculture, the present study aimed to compare growth, gene expression involved in appetite regulation, physical characteristics, and chemical composition of Sparus aurata fed alternative protei...

  • Article
  • Open Access
7 Citations
5,016 Views
11 Pages

Intraduodenal Administration of L-Valine Has No Effect on Antropyloroduodenal Pressures, Plasma Cholecystokinin Concentrations or Energy Intake in Healthy, Lean Men

  • Rachel A. Elovaris,
  • Penelope C. E. Fitzgerald,
  • Vida Bitarafan,
  • Sina S. Ullrich,
  • Michael Horowitz and
  • Christine Feinle-Bisset

5 January 2019

Whey protein is rich in the branched-chain amino acids, L-leucine, L-isoleucine and L-valine. Thus, branched-chain amino acids may, at least in part, mediate the effects of whey to reduce energy intake and/or blood glucose. Notably, 10 g of either L-...

  • Review
  • Open Access
6 Citations
4,491 Views
12 Pages

Alterations in Appetite-Regulating Hormones in Girls with Central Early or Precocious Puberty

  • Galateia Stathori,
  • Anastasia-Maria Tzounakou,
  • George Mastorakos,
  • Nikolaos F. Vlahos,
  • Evangelia Charmandari and
  • Georgios Valsamakis

9 October 2023

The prevalence of central precocious puberty (CPP) in girls has increased worldwide and is often associated with obesity in childhood as well as high fat/high glycemic index diets. Evidence suggests that subjects with obesity present with alterations...

  • Article
  • Open Access
17 Citations
6,986 Views
15 Pages

Satiety Factors Oleoylethanolamide, Stearoylethanolamide, and Palmitoylethanolamide in Mother’s Milk Are Strongly Associated with Infant Weight at Four Months of Age—Data from the Odense Child Cohort

  • Signe Bruun,
  • Sandra Gouveia-Figueira,
  • Magnus Domellöf,
  • Steffen Husby,
  • Lotte Neergaard Jacobsen,
  • Kim F. Michaelsen,
  • Christopher J. Fowler and
  • Gitte Zachariassen

13 November 2018

Regulation of appetite and food intake is partly regulated by N-acylethanolamine lipids oleoylethanolamide (OEA), stearoylethanolamide (SEA), and palmitoylethanolamide (PEA), which induce satiety through endogenous formation in the small intestine up...

  • Concept Paper
  • Open Access
42 Citations
31,799 Views
14 Pages

19 August 2017

Understanding the dynamic nature of energy balance, and the interrelated and synergistic roles of diet and physical activity (PA) on body weight, will enable nutrition educators to be more effective in implementing obesity prevention education. Altho...

  • Brief Report
  • Open Access
2 Citations
1,802 Views
11 Pages

Locked Out: Phoenixin-14 Does Not Cross a Stem-Cell-Derived Blood–Brain Barrier Model

  • Martha A. Schalla,
  • Sabrina Oerter,
  • Alevtina Cubukova,
  • Marco Metzger,
  • Antje Appelt-Menzel and
  • Andreas Stengel

Phoenixin-14 is a recently discovered peptide regulating appetite. Interestingly, it is expressed in the gastrointestinal tract; however, its supposed receptor, GPR173, is predominantly found in hypothalamic areas. To date, it is unknown how peripher...

  • Article
  • Open Access
3,006 Views
13 Pages

Nesfatin-1 in Human Milk and Its Association with Infant Anthropometry

  • Karina D. Honoré,
  • Signe Bruun,
  • Lotte N. Jacobsen,
  • Magnus Domellöf,
  • Kim F. Michaelsen,
  • Steffen Husby and
  • Gitte Zachariassen

30 December 2022

Breastfed infants have different growth patterns to formula-fed infants and are less likely to develop obesity later in life. Nesfatin-1 is an anorexigenic adipokine that was discovered in human milk more than a decade ago, and its role in infant app...

  • Article
  • Open Access
1 Citations
1,195 Views
23 Pages

A Natural Polyphenol, Chlorogenic Acid, Attenuates Obesity-Related Metabolic Disorders in Male Rats via miR-146a-IRAK1-TRAF6 and NRF2-Mediated Antioxidant Pathways

  • Rashid Fahed Alenezi,
  • Adel Abdelkhalek,
  • Gehad El-Sayed,
  • Ioan Pet,
  • Mirela Ahmadi,
  • El Said El Sherbini,
  • Daniela Pușcașiu and
  • Ahmed Hamed Arisha

27 July 2025

Chronic high-fat diet (HFD) feeding in male rats causes significant metabolic as well as inflammatory disturbances, including obesity, insulin resistance, dyslipidemia, liver and kidney dysfunction, oxidative stress, and hypothalamic dysregulation. T...

  • Concept Paper
  • Open Access
30 Citations
20,329 Views
22 Pages

Increasing Energy Flux to Maintain Diet-Induced Weight Loss

  • Christopher L. Melby,
  • Hunter L. Paris,
  • R. Drew Sayer,
  • Christopher Bell and
  • James O. Hill

21 October 2019

Long-term maintenance of weight loss requires sustained energy balance at the reduced body weight. This could be attained by coupling low total daily energy intake (TDEI) with low total daily energy expenditure (TDEE; low energy flux), or by pairing...

  • Review
  • Open Access
4 Citations
4,983 Views
14 Pages

Palmitoylethanolamide in Postmenopausal Metabolic Syndrome: Current Evidence and Clinical Perspectives

  • Alessandro Medoro,
  • Sergio Davinelli,
  • Federica Fogacci,
  • Stefania Alfieri,
  • Domenico Tiso,
  • Arrigo F. G. Cicero and
  • Giovanni Scapagnini

13 December 2024

Menopause leads to a decline in estrogen levels, resulting in significant metabolic alterations that increase the risk of developing metabolic syndrome—a cluster of conditions including central obesity, insulin resistance, dyslipidemia, and hyp...

  • Article
  • Open Access
5 Citations
2,317 Views
11 Pages

Spexin2 Is a Novel Food Regulator in Gallus gallus

  • Fengyan Meng,
  • Yuping Wu,
  • Yu Yu,
  • Guixian Bu,
  • Xiaogang Du,
  • Qiuxia Liang,
  • Xiaohan Cao,
  • Anqi Huang,
  • Xianyin Zeng and
  • Linyan Huang
  • + 3 authors

Spexin2 (SPX2), a paralog of SPX1, is a newly identified gene in non-mammalian vertebrates. Limited studies in fish have evidenced its important role in food intake and energy balance modulation. However, little is known about its biological function...

  • Article
  • Open Access
11 Citations
6,682 Views
13 Pages

The Effect of a 20 km Run on Appetite Regulation in Long Distance Runners

  • Chihiro Kojima,
  • Aya Ishibashi,
  • Kumiko Ebi and
  • Kazushige Goto

26 October 2016

The purpose of the present study was to investigate appetite-related hormonal responses and energy intake after a 20 km run in trained long distance runners. Twenty-three male long-distance runners completed two trials: either an exercise trial consi...

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