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Most Cited

  • Review
  • Open Access
141 Citations
12,993 Views
14 Pages

Bacterial Pathogenesis in Various Fish Diseases: Recent Advances and Specific Challenges in Vaccine Development

  • Aadil Ahmed Irshath,
  • Anand Prem Rajan,
  • Sugumar Vimal,
  • Vasantha-Srinivasan Prabhakaran and
  • Raja Ganesan

17 February 2023

Aquaculture is a fast-growing food sector but is plagued by a plethora of bacterial pathogens that infect fish. The rearing of fish at high population densities in aquaculture facilities makes them highly susceptible to disease outbreaks, which can c...

  • Review
  • Open Access
110 Citations
18,437 Views
34 Pages

An Overview of the Public Health Challenges in Diagnosing and Controlling Human Foodborne Pathogens

  • Ayman Elbehiry,
  • Adil Abalkhail,
  • Eman Marzouk,
  • Ahmed Elnadif Elmanssury,
  • Abdulaziz M. Almuzaini,
  • Hani Alfheeaid,
  • Mohammed T. Alshahrani,
  • Nasser Huraysh,
  • Mai Ibrahem and
  • Feras Alzaben
  • + 6 authors

24 March 2023

Pathogens found in food are believed to be the leading cause of foodborne illnesses; and they are considered a serious problem with global ramifications. During the last few decades, a lot of attention has been paid to determining the microorganisms...

  • Review
  • Open Access
102 Citations
18,581 Views
18 Pages

Recent Advances in the Lipid Nanoparticle-Mediated Delivery of mRNA Vaccines

  • K. Swetha,
  • Niranjan G. Kotla,
  • Lakshmi Tunki,
  • Arya Jayaraj,
  • Suresh K. Bhargava,
  • Haitao Hu,
  • Srinivasa Reddy Bonam and
  • Rajendra Kurapati

14 March 2023

Lipid nanoparticles (LNPs) have recently emerged as one of the most advanced technologies for the highly efficient in vivo delivery of exogenous mRNA, particularly for COVID-19 vaccine delivery. LNPs comprise four different lipids: ionizable lipids,...

  • Article
  • Open Access
100 Citations
9,019 Views
13 Pages

Artificial Intelligence and Public Health: Evaluating ChatGPT Responses to Vaccination Myths and Misconceptions

  • Giovanna Deiana,
  • Marco Dettori,
  • Antonella Arghittu,
  • Antonio Azara,
  • Giovanni Gabutti and
  • Paolo Castiglia

7 July 2023

Artificial intelligence (AI) tools, such as ChatGPT, are the subject of intense debate regarding their possible applications in contexts such as health care. This study evaluates the Correctness, Clarity, and Exhaustiveness of the answers provided by...

  • Review
  • Open Access
81 Citations
22,084 Views
20 Pages

Recent Advances in Lipid Nanoparticles and Their Safety Concerns for mRNA Delivery

  • Jialiang Wang,
  • Yaopeng Ding,
  • Kellie Chong,
  • Meng Cui,
  • Zeyu Cao,
  • Chenjue Tang,
  • Zhen Tian,
  • Yuping Hu,
  • Yu Zhao and
  • Shaoyi Jiang

8 October 2024

Introduction: The advent of lipid nanoparticles (LNPs) as a delivery platform for mRNA therapeutics has revolutionized the biomedical field, particularly in treating infectious diseases, cancer, genetic disorders, and metabolic diseases. Recent Advan...

  • Review
  • Open Access
80 Citations
11,946 Views
19 Pages

17 March 2023

We are currently approaching three years since the beginning of the coronavirus disease 2019 (COVID-19) pandemic. SARS-CoV-2 has caused extensive disruptions in everyday life, public health, and the global economy. Thus far, the vaccine has worked be...

  • Review
  • Open Access
80 Citations
10,124 Views
56 Pages

Next-Generation TB Vaccines: Progress, Challenges, and Prospects

  • Li Zhuang,
  • Zhaoyang Ye,
  • Linsheng Li,
  • Ling Yang and
  • Wenping Gong

31 July 2023

Tuberculosis (TB), caused by Mycobacterium tuberculosis (MTB), is a prevalent global infectious disease and a leading cause of mortality worldwide. Currently, the only available vaccine for TB prevention is Bacillus Calmette–Guérin (BCG)...

  • Review
  • Open Access
77 Citations
14,499 Views
23 Pages

Improved DNA Vaccine Delivery with Needle-Free Injection Systems

  • Carmen Ledesma-Feliciano,
  • Ros Chapman,
  • Jay W. Hooper,
  • Kira Elma,
  • Darin Zehrung,
  • Miles B. Brennan and
  • Erin K. Spiegel

28 January 2023

DNA vaccines have inherent advantages compared to other vaccine types, including safety, rapid design and construction, ease and speed to manufacture, and thermostability. However, a major drawback of candidate DNA vaccines delivered by needle and sy...

  • Review
  • Open Access
77 Citations
11,185 Views
30 Pages

Adenoviral Vector-Based Vaccine Platform for COVID-19: Current Status

  • Vivek P. Chavda,
  • Rajashri Bezbaruah,
  • Disha Valu,
  • Bindra Patel,
  • Anup Kumar,
  • Sanjay Prasad,
  • Bibhuti Bhusan Kakoti,
  • Ajeet Kaushik and
  • Mariya Jesawadawala

13 February 2023

The coronavirus disease (COVID-19) breakout had an unimaginable worldwide effect in the 21st century, claiming millions of lives and putting a huge burden on the global economy. The potential developments in vaccine technologies following the determi...

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Vaccines - ISSN 2076-393X