Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Environmental Contaminants: Impacts on Reproduction and Embryonic Development submission deadline 20 May 2026 | Viewed by 7 | Submission Open
Keywords: environmental contaminants; embryonic development; fertility; toxicity; chemicals
(This special issue belongs to the Section Reproductive and Developmental Biology)
Diagnosis and Management of Maternal Medical Diseases in Pregnancy: Current Practice and Future Perspectives submission deadline 20 May 2026 | Viewed by 6 | Submission Open
Keywords: maternal medical disease; maternal cardiac disease; maternal thyroid disease; gestational diabetes; gestational hypertension; pre-eclampsia; diagnosis; management; maternal and fetal outcomes
(This special issue belongs to the Section Medical Research)
The 15th Anniversary of Life—Alternatives to RNA World
edited by and Amit Kahana
submission deadline 29 May 2026 | Viewed by 115 | Submission Open
Keywords: supramolecular; lipid; assembly; protocell; compositional; information; spontaneous; catalytic; network; reproduction; species; Darwinian; evolution; origin; life
(This special issue belongs to the Section Origin of Life)
Musculoskeletal Disorders: Integrative Insights into Pathophysiology, Therapeutic Strategies, and Rehabilitation
edited by
submission deadline 30 May 2026 | Viewed by 47 | Submission Open
Keywords: musculoskeletal disorders; high-resolution imaging; biomarkers; ultrasound-guided therapy; regenerative medicine; personalized rehabilitation; wearable sensors; translational musculoskeletal research
(This special issue belongs to the Section Medical Research)
New Mechanisms and Insights into Insect Silk Gland Biology and Silk Production
edited by Wenliang Qian
submission deadline 30 May 2026 | Viewed by 16 | Submission Open
Keywords: silk gland morphogenesis; liquid-to-solid phase transition; biomimetic microfluidic spinning; silk gland multi-omics; silk protein evolutionary adaptations; CRISPR
(This special issue belongs to the Section Animal Science)
Advances in Skin-Related Disease: Pathogenesis and Novel Therapeutic Strategies submission deadline 31 May 2026 | 3 articles | Viewed by 1785 | Submission Open
Keywords: skin pathologies; skin cancer; eczema; acne; psoriasis; skin microbiome
(This special issue belongs to the Section Physiology and Pathology)
Recent Advances in Lymphomas
edited by Magdalena Witkowska
submission deadline 31 May 2026 | 1 articles | Viewed by 1054 | Submission Open
Keywords: lymphoma; cellular therapy; epigenetics; immunotherapy; targeted therapies
(This special issue belongs to the Section Medical Research)
Innovative Cardiovascular Interventions: From Imaging to Precision Therapies submission deadline 31 May 2026 | 1 articles | Viewed by 591 | Submission Open
Keywords: cardiovascular diseases (CVDs); diagnostic imaging; minimally invasive interventions; precision medicine; 3D/4D imaging; gene therapy; cell-based therapies
(This special issue belongs to the Section Physiology and Pathology)
Current and Future Perspectives of Takotsubo Syndrome
edited by Luca Arcari
submission deadline 31 May 2026 | 1 articles | Viewed by 72 | Submission Open
Keywords: takotsubo syndrome; heart failure; microvascular dysfunction; inflammation; myocardial edema; heart– brain axis; echocardiography; cardiac magnetic resonance; computed tomography; nuclear imaging
(This special issue belongs to the Section Physiology and Pathology)
Understanding Early Dysmetabolism in Adolescents: Bridging Research, Mechanisms and Clinical Management
edited by Anna Di Sessa
submission deadline 31 May 2026 | Viewed by 45 | Submission Open
Keywords: dysmetabolism; biomarkers; intervention; prevention; early diagnosis; strategies; children; adolescents
(This special issue belongs to the Section Physiology and Pathology)
New Screening Methods for Diagnosis of Cardiovascular Diseases
edited by , Ruxandra Maria Ilie-Mihai and Damaris Cristina Gheorghe
submission deadline 31 May 2026 | Viewed by 41 | Submission Open
Keywords: cardiovascular diseases; biomarkers; screening methods; sensor; spectroscopic methods; chromatographic methods
(This special issue belongs to the Section Medical Research)
Biofluid Mechanics and Medical Diagnostic Simulations submission deadline 31 May 2026 | Viewed by 27 | Submission Open
Keywords: biofluid mechanics; computational modeling; medical diagnostics; fluid-structure interaction; patient-specific modeling
(This special issue belongs to the Section Medical Research)
Physiological, Pathological, and Clinical Effects of Exercise Training and Physical Activity
edited by Chia-Huei Lin
submission deadline 31 May 2026 | Viewed by 18 | Submission Open
Keywords: exercise training; physical activity; individualized exercise prescription; physiological adaptation; chronic disease prevention; cardiovascular fitness; musculoskeletal health; neuroplasticity; metabolic syndrome; inflammation and immunity; stroke recovery; physical activity monitoring; mental health and exercise; cognitive function; aging and physical activity; sedentary behavior; physical function outcomes; patient-reported outcomes; clinical trial
(This special issue belongs to the Section Physiology and Pathology)
Harmful Algal Bloom Risk: Mechanisms, Prediction, Impacts and Mitigation
edited by Lixia Shang
submission deadline 31 May 2026 | Viewed by 12 | Submission Open
Keywords: harmful algal blooms; marine risk; bloom mechanisms; prediction models; mitigation strategies; ecosystem impact
(This special issue belongs to the Section Diversity and Ecology)
Current Advances in Lung Cancer Diagnosis and Treatment
edited by , Daesik Yang and
submission deadline 30 Jun 2026 | 4 articles | Viewed by 4420 | Submission Open
Keywords: lung cancer; underlying lung disease; radiotherapy; systemic therapy; survival outcomes; complication; biomarkers
(This special issue belongs to the Section Medical Research)
Advances in Bioorganic and Medicinal Chemistry
edited by Sahar Kandil
submission deadline 30 Jun 2026 | Viewed by 35 | Submission Open
Keywords: medicinal chemistry; drug discovery; biological chemistry; therapeutic targets; therapeutic agents; treatment of diseases; new therapeutic strategies
New Advances in the Treatment and Assessment of Temporomandibular Joint Disorders submission deadline 30 Jun 2026 | Viewed by 2 | Submission Open
Keywords: orofacial dysfunction; multifactorial etiology; advanced diagnostic technologies; biomechanical modeling of TMJ; novel imaging techniques; inflammatory and degenerative changes; interdisciplinary management; conservative therapy approaches; occlusal concepts; splint therapy design; physical therapy regimens; long-term implant treatment outcomes; personalized treatment strategies
(This special issue belongs to the Section Medical Research)
Emerging Knowledge on Human Immunodeficiency Virus submission deadline 22 Jul 2026 | 2 articles | Viewed by 10417 | Submission Open
Keywords: HIV; antiretroviral treatment; long-acting ART; pre-exposure prophylaxis; HIV surveillance; antiretroviral resistance; primary resistance; HIV epidemiology; special populations; cascade of care; HIV diagnosis
(This special issue belongs to the Section Medical Research)
Promising Therapeutic Horizons for Regenerative Medicine in Animals submission deadline 28 Jul 2026 | Viewed by 114 | Submission Open
Keywords: stem cells; induced pluripotent stem cells (iPSCs); soft tissue engineering; in vivo and in vitro investigations; extracellular vesicles; preclinical studies; clinical studies; platelet-rich plasma; platelet-rich fibrin; cell-based therapy; cell-free therapy; orthopedics; cardiology
(This special issue belongs to the Section Animal Science)
Vetinformatics-Driven Approaches to Animal Health and Disease
edited by and Rajesh Kumar Pathak
submission deadline 31 Jul 2026 | Viewed by 174 | Submission Open
Keywords: animal health; livestock disease; vetinformatics; computational genomics; RNAseq; multi-omics; drug discovery; molecular docking; molecular dynamics simulation; vaccine design; one health
(This special issue belongs to the Section Animal Science)
Oral Health and Systemic Conditions: From Biological Insights to Multidimensional Interventions submission deadline 27 Aug 2026 | Viewed by 79 | Submission Open
Keywords: oral health  ; periodontitis  ; dental care  ; tooth loss  ; oral cancer  ; facial esthetics  ; salivary biomarkers  ; systemic– oral health interactions  ; non-invasive therapies  ; clinical and epidemiological research
(This special issue belongs to the Section Medical Research)
Pathology, Diagnosis, and Treatments of Airway Diseases submission deadline 1 Oct 2026 | Viewed by 140 | Submission Open
Keywords: airway diseases; COPD; asthma; cystic fibrosis; bronchiectasis; biomarkers; biologics; targeted; immunology; pathogenesis
(This special issue belongs to the Section Medical Research)
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