Recent Advances in Vascular Biology and Chronic Kidney Disease (CKD)

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".

Deadline for manuscript submissions: 30 September 2025 | Viewed by 1050

Special Issue Editor


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Guest Editor
Department of Microbiology, College of Medicine, Kyung Hee University, Seoul 02447, Republic of Korea
Interests: vascular biology; diabetes; oxidative stress; inflammation; autophagy; atherosclerosis; artificial vessels; mitochondria
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Special Issue Information

Dear Colleagues,

We are excited to announce a Special Issue focusing on vascular biology and chronic kidney disease (CKD), which will be dedicated to sharing cutting-edge knowledge on the interplay between vascular biology and CKD. This Special Issue will provide a platform to discuss innovative findings that can enhance our understanding of vascular systems and their critical role in CKD progression, while facilitating advancements in therapeutic strategies to combat CKD-related vascular dysfunction.

The vascular endothelium, composed of a monolayer of cells, is a vital organ in regulating vascular functions. It plays key roles in vascular growth and remodeling, the modulation of immune and thrombotic responses, and the maintenance of homeostasis and angiogenesis through interactions between the vessel wall and immune cells. Endothelial dysfunction is a major contributor to CKD-related complications, including reduced renal blood flow, vascular calcification, and heightened cardiovascular risk.

For this Special Issue, we invite researchers to contribute original research articles, review articles, and clinical studies that can advance our understanding of vascular biology in the context of CKD, aiming to facilitate efforts that will pave the way for improved therapeutic approaches.

Prof. Dr. Yongseek Park
Guest Editor

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Keywords

  • chronic kidney disease
  • vascular dysfunction
  • endothelial cells

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Published Papers (1 paper)

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Review

30 pages, 675 KiB  
Review
Individualized Diets in Patients with Kidney Disease and Kidney Transplants: A Narrative Review
by Lilio Hu, Greta Borelli, Elisa Gessaroli, Chiara Ruotolo, Sofia Bin, Giuliana Papalia, Gemma Patella, Maria Elena Liberti, Olga Baraldi, Gianluigi Zaza, Irene Capelli and Michele Provenzano
Life 2025, 15(6), 896; https://doi.org/10.3390/life15060896 - 31 May 2025
Viewed by 828
Abstract
Chronic kidney disease (CKD) is a widespread condition with significant cardiovascular risks and a progression to end-stage kidney failure. In recent years, increasing attention has been paid to the role of dietary interventions as a factor capable of influencing disease trajectory. This review [...] Read more.
Chronic kidney disease (CKD) is a widespread condition with significant cardiovascular risks and a progression to end-stage kidney failure. In recent years, increasing attention has been paid to the role of dietary interventions as a factor capable of influencing disease trajectory. This review summarizes the current observational and interventional evidence on various dietary approaches in patients with CKD and kidney transplants (KTs), including Mediterranean, plant-based, and low-protein diets. A balanced Mediterranean diet, rich in fruits, vegetables, whole grains, fish, and unsaturated fats, shows promises in improving the prognosis for CKD patients. Plant-based diets, which emphasize legumes, vegetables, and grains while minimizing animal protein, improve blood pressure and the glycemic and lipid control. Low-protein diets (LPDs), typically providing less than 0.6 g/kg/day of protein, may reduce the CKD progression and nitrogen burden, further delaying the initiation of dialysis. In conclusion, diets represent a valuable and underutilized therapeutic strategy in the management of CKD and KTs, influencing disease progression and patient outcomes. Full article
(This article belongs to the Special Issue Recent Advances in Vascular Biology and Chronic Kidney Disease (CKD))
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