Neuroimaging and Integrative Analyses in Psychiatry and Addictive Disorders

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".

Deadline for manuscript submissions: 30 June 2026 | Viewed by 1649

Special Issue Editor


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Guest Editor
Grüner Kreis Association, Vienna, Austria
Interests: psychiatry; forensic psychiatry; addiction; neuroimaging; human rights
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Special Issue Information

Dear Colleagues,

This Special Issue aims to bring together original research, reviews, and meta-analyses exploring the integration of neuroimaging features in relation to the diagnosis, treatment, and prevention of psychiatric and addictive disorders.

The scope of this issue includes studies on neuroimaging, neural mechanisms, and the identification of biomarkers. Submissions on forensic psychiatry, psychotherapy, and neuropsychiatric disorders such as treatment-resistant depression (TRD), substance use disorder (SUD), and attention-deficit hyperactivity disorder (ADHD) are particularly encouraged, with a focus on evaluating clinical outcomes and correlates of human brain function. Key areas of interest include functional and structural imaging techniques (e.g., fMRI, PET, EEG). Furthermore, translational research linking imaging findings to therapeutic applications, including psychotherapeutic and pharmacological interventions, as well as studies exploring the implementation of artificial intelligence, are also considered.

Multimodal data analyses on imaging genetics, transcriptomics, and computational psychiatry shall highlight emerging trends and unmet needs for personalized medicine, fostering collaboration among researchers, clinicians, and forensic experts. By providing a platform for integrative and multidisciplinary approaches, we aim to advance the understanding of psychiatric and addictive disorders.

We welcome manuscript suggestions on these topics and encourage authors to contact the editors for a pre-arrangement regarding their submissions before preparing their manuscripts.

Dr. Arkadiusz Komorowski
Guest Editor

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Keywords

  • psychiatry
  • neuroimaging
  • forensic psychiatry
  • fMRI
  • PET
  • EEG
  • addiction
  • substance use disorders (SUD)
  • psychotherapy
  • treatment-resistant depression (TRD)
  • attention deficit hyperactivity disorder (ADHD)

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Published Papers (1 paper)

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Research

17 pages, 1460 KB  
Article
Neural Correlates of Personality Traits in Adolescents Exhibiting Excessive Smartphone Use: A Resting-State FMRI Study
by Min Kyung Hu, Kyeong Seob Song, Jihye Choi, Arom Pyeon, Hyun Cho, Jung-Seok Choi, Inyoung Choi, Ji-won Chun and Dai-Jin Kim
Life 2025, 15(12), 1899; https://doi.org/10.3390/life15121899 - 12 Dec 2025
Viewed by 1105
Abstract
Background: Although smartphone usage is inevitable and convenient in recent days, numerous potential problems due to excessive smartphone use (ESU) have been highlighted. With the rising concern about ESU, the focus on exploring the relationship between ESU and personality traits and their neural [...] Read more.
Background: Although smartphone usage is inevitable and convenient in recent days, numerous potential problems due to excessive smartphone use (ESU) have been highlighted. With the rising concern about ESU, the focus on exploring the relationship between ESU and personality traits and their neural correlations also increased; however, studies that explore these factors simultaneously are lacking. Objective: This study investigated whether altered resting state functional connectivity (rsFC) is related to personality traits in adolescents exhibiting ESU compared to healthy controls (HCs). Methods: Thirty-one adolescents exhibiting ESU and 31 HCs (62 adolescents) aged 12–18 years were included in this study. Seed-to-voxel connectivity analysis was used to examine group differences in rsFC in the middle cingulate cortex (MCC) and insula, key parts of the salience network, in relation to personality traits. Results: Adolescents exhibiting ESU showed trends toward low persistence and high harm avoidance in terms of personality traits. Additionally, they exhibited enhanced rsFC between the MCC and insula but reduced rsFC between the precentral and postcentral gyri compared with HCs. Notably, increased rsFC between the MCC and insula in the ESU group was negatively correlated with low persistence. Conclusions: ESU was associated with low persistence at the uncorrected threshold in terms of personality traits and involved in neuro-functional alterations between the key hubs of the salience network, MCC, insula, and several other brain regions. These findings may provide a neurobiological basis for intervention targeting behavioral addiction in youth. Accordingly, adolescents with low persistence may need tailored education on appropriate and controlled use of smartphones and internet-based technologies. Full article
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