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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Microvascular Dynamics: Insights and Applications

edited by

Aristotle G. Koutsiaris

and Friedrich Jung

submission deadline 26 Jun 2025 | 6 articles | Viewed by 10617 | Submission Open

Keywords: microvessels; dynamics; velocity; flow; rheology; in vitro; animals; humans; biomarkers; imaging; simulations; models; preclinical; clinical

(This special issue belongs to the Section Physiology and Pathology)

Innovative Strategies in Insecticide Resistance and Sustainable Pest Management

edited by Chengwang Sheng,

Jinda Wang

and

Bin Zhu

submission deadline 27 Jun 2025 | 1 articles | Viewed by 1515 | Submission Open

Keywords: insecticide resistance; sustainable pest management; integrated pest management; bioinsecticides; physical pest control; gene editing; insect sterilization; transgenic technology; molecular targets for pesticides

(This special issue belongs to the Section Animal Science)

From Stem Cells to Embryos, Congenital Anomalies and Epidemiology

edited by

Maria Eleni Manthou

, Soultana Meditskou and

Paschalis Theotokis

submission deadline 30 Jun 2025 | 7 articles | Viewed by 18066 | Submission Open

Keywords: stem cell research; human embryonic development; birth defects epidemiology; birth defects prevalence; maternal and fetal medicine; congenital anomalies prevention; ultrasound evaluation; pre-birth assessment; prenatal screening; healthcare

(This special issue belongs to the Section Epidemiology)

Retinal Diseases: From Molecular Mechanisms to Therapeutics

edited by

Soo-Young Kim

submission deadline 30 Jun 2025 | 7 articles | Viewed by 14892 | Submission Open

Keywords: retinal disease; inflammatory disease; genetic diseases; ocular drug development

(This special issue belongs to the Section Physiology and Pathology)

New Horizons of Adipose Tissue Disorders: From Hormonal Issues to Loose Connective Disease

edited by

Laura Patton

and

Guido Gabriele

submission deadline 30 Jun 2025 | 4 articles | Viewed by 13347 | Submission Open

Keywords: adipose tissue; lipedema; lymphedema; obesity; matrix; vascular and lymphatic disorder; connective tissue diseases; dysbiosis; inflammation; pain

(This special issue belongs to the Section Physiology and Pathology)

New Insights into Allergic Eye Diseases

edited by

De Gaulle I. Chigbu

and

Livio Vitiello

submission deadline 30 Jun 2025 | 2 articles | Viewed by 11929 | Submission Open

Keywords: allergy; IgE; IL-4; IL-5; IL-13; TNF-alpha; mast cells; eosinophils; Th1 cells; Th2 cells; therapeutics; immunopathogenesis; immunopathology; conjunctivitis; keratoconjunctivitis

(This special issue belongs to the Section Medical Research)

Nutritional Supplements and Cardiovascular Function in Athletes and Sedentary People

edited by

Ines Drenjančević

submission deadline 30 Jun 2025 | 4 articles | Viewed by 6162 | Submission Open

Keywords: athletes; sedentary; eating habits; nutrition; endothelium; microcirculation; vascular function; nutritional supplements; oxidative stress; antioxidants; NRF2-signaling pathway; functional food; cardiovascular function; prevention; physical activity

(This special issue belongs to the Section Medical Research)

Advances in Endoscopic, Surgical, and Interventional Radiological Management of Gastrointestinal Diseases

edited by

Beata Jabłońska

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4501 | Submission Open

Keywords: gastrointestinal disease; endoscopic cystogastrostomy; endoscopic biliary prosthesis; endoscopic pancreatic prosthesis; endoscopic necrosectomy; esophagectomy; gastrectomy; bowel resection; colectomy; pancreatectomy; hepatectomy; liver transplantation; gastroenterology; surgery; interventional radiology

(This special issue belongs to the Section Medical Research)

Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders

edited by

Marco Gesi

Mario Vetrano

, Maria Chiara Vulpiani, Maria Cristina D'Agostino, Larisa Ryskalin and Federica Fulceri

submission deadline 30 Jun 2025 | 3 articles | Viewed by 4491 | Submission Open

Keywords: shockwave; tissue regeneration; pain; functional recovery and healing; physical medicine and rehabilitation; clinical applications; imaging

(This special issue belongs to the Section Medical Research)

Innovative Applications of Extracellular Vesicles: From Diagnostics to Drug Delivery

edited by Alessandra Lo Cicero

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3883 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer; cardiovascular diseases; neurodegenerative diseases; biomarkers; diagnostics; cell-cell communication; drug delivery; therapeutics

(This special issue belongs to the Section Physiology and Pathology)

Eye Diseases: Diagnosis and Treatment, 3rd Edition

edited by

Alba Martín-Gil

and Laura De Diego-García

submission deadline 30 Jun 2025 | 4 articles | Viewed by 3756 | Submission Open

Keywords: ocular treatment; ocular diseases; retina; anterior eye; posterior eye; ocular biomarkers

(This special issue belongs to the Section Medical Research)

Revolutionizing Neuroregeneration

edited by

Kiminobu Sugaya

submission deadline 30 Jun 2025 | 3 articles | Viewed by 3281 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; neuroregeneration; stroke; regenerative therapy

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Musculoskeletal Pain and Disorders: Diagnosis, Treatment and Management

edited by

Antonio Stecco

and

Carmelo Pirri

submission deadline 30 Jun 2025 | 1 articles | Viewed by 3253 | Submission Open

Keywords: pain; connective tissue; musculoskeletal disorders; fascia; muscles; tendons; ligaments

(This special issue belongs to the Section Physiology and Pathology)

Epidemiology Studies of Cardiovascular Diseases in Older Adults

edited by Nadya Kagansky

submission deadline 30 Jun 2025 | 2 articles | Viewed by 3182 | Submission Open

Keywords: cardiovascular diseases in older adults; gerontology; hypertension; hyperlipidemia; diabetes; obesity

(This special issue belongs to the Section Epidemiology)

Bone Remodeling

edited by

Tada-aki Kudo

submission deadline 30 Jun 2025 | 3 articles | Viewed by 3152 | Submission Open

Keywords: bone remodeling; osteoblast; osteoclast; osteocyte; osteoporosis

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Physiological Responses of Plants Under Abiotic Stresses

edited by Dawei Shi

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2921 | Submission Open

Keywords: crops; woody plants; horticultural plants; physiological responses; abiotic stresses; photosynthesis

(This special issue belongs to the Section Plant Science)

Current Advances in Lung Cancer Diagnosis and Treatment

edited by

Hakyoung Kim

, Daesik Yang and

Zhiwei Hu

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2397 | Submission Open

Keywords: lung cancer; underlying lung disease; radiotherapy; systemic therapy; survival outcomes; complication; biomarkers

(This special issue belongs to the Section Medical Research)

Neuroinflammation in Huntington’s Disease: Detrimental Crosstalk

edited by

Michele D'Angelo

and

Vanessa Castelli

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2084 | Submission Open

Keywords: Huntington’ s disease; mutant huntingtin (mHtt) protein; central nervous system; mutated protein; glial cells

(This special issue belongs to the Section Physiology and Pathology)

Genetics, Breeding and Reproduction of Honeybees: Second Edition

edited by

Xiao Chen

submission deadline 30 Jun 2025 | 2 articles | Viewed by 2011 | Submission Open

Keywords: phenomics; genetics; genomics; functional genomics; metabolomics; functional genes identification; genetics editing; genome selection; genetic evaluation; hybrid breeding; egg-laying; honey production; queen breeding; varroa resistance

(This special issue belongs to the Section Animal Science)

Advancements in Veterinary Oncology

edited by

José Pimenta

Mário Pedro Goncalves Cotovio

Justina Prada

and

Isabel Pires

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1972 | Submission Open

Keywords: veterinary and comparative oncology; epidemiology; tumor biology; diagnosis; treatment; biomarkers

(This special issue belongs to the Section Animal Science)

Feature Paper in Genetics and Genomics

edited by

Lluís Ribas de Pouplana

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1965 | Submission Open

Keywords: DNA; RNA; gene discovery and function; gene expression; population genetics; genome projects; comparative and functional genomics; medical genetics; complex traits; chromosome biology; epigenomics and epigenetics; statistical genetics and methodology; genomic assay technology; sequencing technologies; bioinformatics

(This special issue belongs to the Section Genetics and Genomics)

Veterinary Pathology and Veterinary Anatomy: 3rd Edition

edited by

Gheorghe Solcan

and

Carmen Solcan

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1898 | Submission Open

Keywords: veterinary pathology; veterinary anatomy; SARS-CoV-2 pandemic; climate change; environmental pollution; diagnosis and treatment of animal diseases; computer modelling of pathological processes

(This special issue belongs to the Section Animal Science)

Advanced Heart Failure and Transplant Cardiology

edited by David Dobarro

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1689 | Submission Open

Keywords: heart failure; heart transplantation; cardiology; ventricular assist devices

(This special issue belongs to the Section Medical Research)

Acute Kidney Events in Intensive Care

edited by

Silvia De Rosa

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1583 | Submission Open

Keywords: acute kidney events; ICU; critically ill; RRT; outcome; acute kidney disease; chronic kidney disease; biomarkers

(This special issue belongs to the Section Medical Research)

Mechanism, Diagnosis, and Treatment of Aortic Diseases: 2nd Edition

edited by

Edit Dósa

submission deadline 30 Jun 2025 | 2 articles | Viewed by 1415 | Submission Open

Keywords: aorta; aortic disease; aortic aneurysm; aortic dissection; penetrating aortic ulcer; aortic stenosis; arteritis; pathomechanism; diagnosis; pharmacological therapy; invasive therapy; endovascular therapy; open surgery

(This special issue belongs to the Section Medical Research)

Mechanism, Diagnostic and Therapeutic Novelties in Dermatology: 3rd Edition

edited by Jose Carlos Armario Hita,

Jose Juan Pereyra Rodriguez

and

Ricardo Ruiz-Villaverde

submission deadline 30 Jun 2025 | 1 articles | Viewed by 1081 | Submission Open

Keywords: physiopathology; skin sonography; dermoscopy; innovation; confocal microscopy; biological treatment; psoriasis; atopic dermatitis; inmmunomediated diseases; urticaria; laser CO2

(This special issue belongs to the Section Medical Research)

Innovative Technologies in Pain Management

edited by

Hector Beltran-Alacreu

and

José A. Moral-Munoz

submission deadline 30 Jun 2025 | 1 articles | Viewed by 910 | Submission Open

Keywords: pain management; extended reality (XR) technologies; gamification for pain relief; psychosocial variables; interdisciplinary approaches

(This special issue belongs to the Section Physiology and Pathology)

Advances and Applications of Neuroimaging in Brain Disorder

edited by Julio Plata-Bello

submission deadline 30 Jun 2025 | 1 articles | Viewed by 871 | Submission Open

Keywords: neuroimaging; magnetic resonance imaging; positron emission tomography; near infrared spectroscopy; brain; dementia; schizophrenia; depression; brain tumors; multiple sclerosis; autism

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Advancements in Hematologic Malignancies: Innovations in Diagnosis and Therapy

edited by Chohao Lee

submission deadline 30 Jun 2025 | 1 articles | Viewed by 841 | Submission Open

Keywords: hematologic malignancies; stem cell transplantation; CAR-T cell therapy; immunotherapy; multiple myeloma; leukemia; precision medicine; hematopoietic stem cells; drug resistance; novel therapeutics

(This special issue belongs to the Section Medical Research)

Diabetes and Microbiome

edited by

Gratiela Pircalabioru

and

Octavian Savu

submission deadline 30 Jun 2025 | Viewed by 403 | Submission Open

Keywords: diabetes mellitus; microbiome; microbiota metabolites; metabolic disease; dysbiosis

(This special issue belongs to the Section Microbiology)

Prevention, Evaluation, and Control of HIV Infection

edited by

Οlga Tsachouridou

submission deadline 30 Jun 2025 | 1 articles | Viewed by 295 | Submission Open

Keywords: HIV/AIDS; HIV testing; immune activation; HIV pathogenesis; inflammation; HIV transmission and prevention; antiretroviral therapy

(This special issue belongs to the Section Microbiology)

Advanced Neuroimaging Techniques in Stroke Management

edited by Foteini Christidi,

Anna Tsiakiri

and Efstratios Karavasilis

submission deadline 30 Jun 2025 | Viewed by 286 | Submission Open

Keywords: stroke; neuroimaging; MRI; CT; stroke management; biomarkers; acute stroke; chronic stroke; neuroplasticity; neuromodulation

(This special issue belongs to the Section Medical Research)

Chronic Obstructive Pulmonary Disease: Clinical, Epidemiological, and Molecular Bases

edited by

Josef Yayan

submission deadline 30 Jun 2025 | Viewed by 263 | Submission Open

Keywords: chronic obstructive pulmonary disease; COPD; emphysema; chronic bronchitis

(This special issue belongs to the Section Medical Research)

Biological Insights into Drug Safety for Vulnerable Populations

edited by

Dulce Estêvão

and

Margarida Espírito-Santo

submission deadline 30 Jun 2025 | Viewed by 242 | Submission Open

Keywords: drug safety; vulnerable populations; pharmacotherapy; drug metabolism and efficacy; pediatric medication safety; drug pharmacokinetics and pharmacodynamics

(This special issue belongs to the Section Pharmaceutical Science)

Recent Advances in Valve Therapy: Clinical and Molecular Perspectives

edited by

Panayotis Vlachakis

, Konstantinos Toutouzas and Constantina Aggeli

submission deadline 30 Jun 2025 | Viewed by 213 | Submission Open

Keywords: transcatheter aortic valve implantation (TAVI); valve-in-valve; long-term outcomes; aortic stenosis; molecular mechanisms in valve disease; structural heart disease

(This special issue belongs to the Section Medical Research)

Recent Advances in Non-Invasive Diagnosis Based on Volatile Metabolites

edited by Kiran Sankar Maiti

submission deadline 30 Jun 2025 | Viewed by 209 | Submission Open

Keywords: volatile metabolites; breath analysis; headspace analysis; biofluids; non-invasive; diagnosis

(This special issue belongs to the Section Medical Research)

The Other Pediatric Primary Headaches: 2nd Edition

edited by

Vincenzo Raieli

Vittorio Sciruicchio

and Giuseppe Santangelo

submission deadline 30 Jun 2025 | Viewed by 181 | Submission Open

Keywords: pediatric TACs; primary pediatric headaches; pediatric tension headaches; preventive treatment; acute treatment; clinical features; children; pediatric headaches in IV 3ICHD

(This special issue belongs to the Section Medical Research)

Integrating Bioinformatics and Artificial Intelligence: Transforming Data into Insights for Precision Medicine

edited by Usef Faghihi

submission deadline 30 Jun 2025 | Viewed by 174 | Submission Open

Keywords: bioinformatics; artificial intelligence; precision medicine; machine learning; computational biology; multi-omics data integration; biomarker discovery; predictive modeling; personalized medicine; computational drug discovery

(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)

Advances in CT Angiography and Perfusion

edited by Marcin Sawicki

submission deadline 30 Jun 2025 | Viewed by 172 | Submission Open

Keywords: CT angiography; CT perfusion; artificial intelligence; dynamic CT angiography; 4D CT angiography; acute ischemic stroke

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Advances in Veterinary Ophthalmology: Innovative Approaches to Ocular Diseases in Animals

edited by

Dagmara Winiarczyk

submission deadline 30 Jun 2025 | Viewed by 162 | Submission Open

Keywords: ocular diseases; dogs; cats; tear film; molecular mechanism

(This special issue belongs to the Section Animal Science)

Role of the Kynurenine System in Neurological Disorders

edited by

Gábor Nagy-Grócz

and Tamás Körtési

submission deadline 30 Jun 2025 | Viewed by 141 | Submission Open

Keywords: kynurenine pathway; neurological disorders; kynurenic acid; quinolinic acid

(This special issue belongs to the Section Physiology and Pathology)

Innovations in Pediatric Immunology and Environmental Health

edited by

Wonsuck Yoon

submission deadline 30 Jun 2025 | Viewed by 113 | Submission Open

Keywords: indoor microbiome; children's health; environmental microorganisms; maternal factors; allergies and asthma; immune development

(This special issue belongs to the Section Physiology and Pathology)

Infection, Inflammation and Rheumatology

edited by

Arvind Nune

submission deadline 4 Jul 2025 | 1 articles | Viewed by 1566 | Submission Open

Keywords: infection; COVID-19; inflammation; vaccination; rheumatic diseases

(This special issue belongs to the Section Physiology and Pathology)

Update on Microalgae Metabolites

edited by

Eduardo Jacob-Lopes

and

Leila Queiroz Zepka

submission deadline 10 Jul 2025 | 1 articles | Viewed by 1302 | Submission Open

Keywords: biosynthesis; culture conditions; bioactive compounds; biological activity; biorefinery; proteins; peptides; antifreeze proteins; enzymes; carbohydrates; exocellular polysaccharides; carbohydrate-binding proteins; lipids; fatty acids; chlorophylls; carotenoids; phycobiliproteins; vitamins; minerals; trace elements; sterols; secondary metabolites; downstream processing; purification; safety; regulatory issues; clinical tests

(This special issue belongs to the Section Microbiology)

Regulation of Cerebrovascular Resistance in Health and Disease: From Molecules to Humans

edited by

Akos Koller

submission deadline 11 Jul 2025 | Viewed by 159 | Submission Open

Keywords: cerebral blood flow; hemodynamic forces; cerebrovascular resistance; endothelium; smooth muscle; arachidonic acid metabolites; reactive oxygen species; molecular mediators; protein and mRNA expressions; brain disease conditions; transcranial Doppler measurement; EEG; lifestyle

(This special issue belongs to the Section Physiology and Pathology)

Molecular Mechanisms and Function Impact of Protein Modifications

edited by

Yie Hwa Chang

submission deadline 15 Jul 2025 | Viewed by 177 | Submission Open

Keywords: protein modifications; enzyme regulation; proteomics and functional; diversity disease mechanisms; diagnostic and therapeutic strategies

(This special issue belongs to the Section Proteins and Proteomics)

Cancer Treatment and Drug Resistance: 2nd Edition

edited by

Zhixiang Wang

and

Hamid Maadi

submission deadline 20 Jul 2025 | Viewed by 164 | Submission Open

Keywords: cancer treatment; drug resistance; cancer cell signaling; metastasis; apoptosis; cell cycle; novel therapies

(This special issue belongs to the Section Pharmaceutical Science)

Cardioncology: From Molecular Mechanisms to Advanced Imaging and New Treatments

edited by

Carla Contaldi

, Giuseppe Pacileo and

Paolo Calabrò

submission deadline 21 Jul 2025 | 2 articles | Viewed by 2798 | Submission Open

Keywords: cardiotoxicity; echocardiography; cardiac magnetic resonance; cardiac computed tomography; serum cardiac biomarkers; cancer therapy; arrhythmias; cardiotoxicity treatment

(This special issue belongs to the Section Physiology and Pathology)

Emerging Knowledge on Human Immunodeficiency Virus

edited by

Giota Lourida

and

Dimitrios Paraskevis

submission deadline 22 Jul 2025 | 2 articles | Viewed by 5170 | Submission Open

Keywords: HIV; antiretroviral treatment; long-acting ART; pre-exposure prophylaxis; HIV surveillance; antiretroviral resistance; primary resistance; HIV epidemiology; special populations; cascade of care; HIV diagnosis

(This special issue belongs to the Section Medical Research)

Critical Issues in Intensive Care Medicine

edited by

Janos Szederjesi

submission deadline 22 Jul 2025 | 3 articles | Viewed by 2633 | Submission Open

Keywords: critical issues; intensive care; co-morbidities in ICUs; new technology issues in ICUs; hospital-acquired infections; end of life

(This special issue belongs to the Section Medical Research)

Displaying special issue 51-100 on page 2 of 9.

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