Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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2nd Edition—Food Microbiological Contamination submission deadline 30 Sep 2025 | Viewed by 165 | Submission Open
Keywords: food safety; food microbiology; foodborne pathogens; food spoilage; food quality; food contamination; microbiological hazards; natural antimicrobials
(This special issue belongs to the Section Microbiology)
Advances in Microvascular Research: 2nd Edition submission deadline 30 Sep 2025 | Viewed by 149 | Submission Open
Keywords: microvascular injury; microvascular dysfunction; microcirculation; vascular inflammation; hypertension; cardiovascular diseases
(This special issue belongs to the Section Physiology and Pathology)
Synthetic Genetic Elements, Devices, and Systems: 2nd Edition
edited by and
submission deadline 30 Sep 2025 | Viewed by 145 | Submission Open
Keywords: synthetic biology; synthetic genetic elements/parts; biobricks; artificial gene synthesis; biocomputing; directed evolution; metabolic engineering/cell factory; optogenetics; genetic code expansion; xenobiology
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Research Progress of Cultivation of Edible Fungi: 2nd Edition
edited by Yajie Zou
submission deadline 30 Sep 2025 | Viewed by 141 | Submission Open
Keywords: edible fungi; cultivation; domesticate; substrate; biological efficiency; nutritional properties; functional compounds; sustainability; commercialization; emerging species
(This special issue belongs to the Section Microbiology)
Autoimmune Disorders: From Pathophysiology to Therapeutics
edited by and Chiara Mura
submission deadline 30 Sep 2025 | Viewed by 119 | Submission Open
Keywords: autoimmunity; autoimmune diseases; polyglandular autoimmune syndromes; thyroid autoimmune disease; type 1 diabetes
(This special issue belongs to the Section Physiology and Pathology)
Computational Approaches in Breast Cancer Diagnosis and Prognosis
edited by Elham Pashaei and
submission deadline 30 Sep 2025 | Viewed by 110 | Submission Open
Keywords: bioinformatics; machine learning; artificial intelligence; breast cancer
(This special issue belongs to the Section Physiology and Pathology)
Updates on Cancer Immunology and Immunotherapy
edited by Parnian Jabbari
submission deadline 30 Sep 2025 | Viewed by 108 | Submission Open
Keywords: cancer immunology; immunotherapy; immune checkpoints; tumor microenvironment; chimeric antigen receptor T-cell (CAR-T) therapy; cancer vaccines; immune evasion; tumor immunity; personalized immunotherapy; immune oncology; combination therapy; immune-related adverse events; neoantigens; adoptive cell transfer; oncolytic viruses; targeted immunotherapy; tumor-associated antigens; cancer immunosurveillance; resistance mechanisms; clinical trials in immunotherapy
(This special issue belongs to the Section Medical Research)
Advances in Congenital Diaphragmatic Hernia: From Clinical Features to Management
edited by Przemysław Kosinski
submission deadline 30 Sep 2025 | Viewed by 103 | Submission Open
Keywords: congenital diaphragmatic hernia; prenatal diagnosis; fetal interventions; neonatal management; pulmonary hypoplasia; surgical techniques; imaging techniques; genetic testing; FETO; comprehensive care protocols  
(This special issue belongs to the Section Medical Research)
New Insights into Diagnosis and Therapeutic Strategies for Chronic Liver Diseases
edited by
submission deadline 20 Oct 2025 | 2 articles | Viewed by 1658 | Submission Open
Keywords: chronic liver disease; metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); drug-induced liver injury (DILI); hepatocellular carcinoma; biomarkers of liver fibrosis; imaging of liver fibrosis; CEUS; novel therapeutic strategies for CLDs
(This special issue belongs to the Section Medical Research)
Cell-Free DNA as a Biomarker in Metabolic Diseases
edited by
submission deadline 20 Oct 2025 | Viewed by 114 | Submission Open
Keywords: cell-free DNA (cfDNA); liquid biopsy; metabolic diseases; obesity; type 2 diabetes; non-alcoholic fatty liver disease (NAFLD); methylation; mutations
(This special issue belongs to the Section Medical Research)
Sensitization via Skin Exposure
edited by
submission deadline 20 Oct 2025 | Viewed by 65 | Submission Open
Keywords: contact dermatitis; patch test; epidemiology; occupation; prevention
Developments in the Interrelation of Gut Microbiota and Immune System for Treatment Strategies
edited by
submission deadline 20 Oct 2025 | Viewed by 62 | Submission Open
Keywords: gut microbiota; innate immune system; immunotherapy; dysbiosis;   bifidobacterium; microbiota modulation; probiotics; prebiotics; symbiotics; postbiotics; cancer immunotherapy; autoimmune diseases; vaccine response; immune regulation; therapeutic microbiology; translational medicine
(This special issue belongs to the Section Medical Research)
Diversity and Evolution of Pathogenic Viruses
edited by
submission deadline 20 Oct 2025 | Viewed by 42 | Submission Open
Keywords: pathogenic viruses; biologic diversity; evolution
(This special issue belongs to the Section Medical Research)
Cancer Epidemiology
edited by Daniela-Cristina Stefan and Honoré K. Mitonga
submission deadline 24 Oct 2025 | 4 articles | Viewed by 5068 | Submission Open
Keywords: cancer disparities; specific populations; methodological advances; cancer trends; cancer causes; prevention strategies
(This special issue belongs to the Section Epidemiology)
Dive into Myopia
edited by
submission deadline 24 Oct 2025 | Viewed by 157 | Submission Open
Keywords: myopia; hyperopia; myopia control; axial length; axial length retardation; axial length elongation; myopia complications; refraction measurement; atropine; rebound effect; orthokeratology; missight; defocus incorporated multiple segments (DIMSs); highly aspherical lenslets (HALs); red light; repeated low-level red light (RLRL) therapy; enhance myopia control; customized myopia control; peripheral refraction; peripheral myopia; refractive surgery; PRK; LASIK; smile; contact lens; spectacles
(This special issue belongs to the Section Medical Research)
Neuroimaging and Integrative Analyses in Psychiatry and Addictive Disorders
edited by Arkadiusz Komorowski
submission deadline 25 Oct 2025 | Viewed by 148 | Submission Open
Keywords: psychiatry; neuroimaging; forensic psychiatry; fMRI; PET; EEG; addiction; substance use disorders (SUD); psychotherapy; treatment-resistant depression (TRD); attention deficit hyperactivity disorder (ADHD)
(This special issue belongs to the Section Physiology and Pathology)
Laparoscopy and Treatment: An All-Encompassing Solution for Surgeons
edited by Niculae Iordache and Claudiu-Octavian Ungureanu
submission deadline 26 Oct 2025 | 1 articles | Viewed by 890 | Submission Open
Keywords: oncological; staging laparoscopy; tool; radical surgery; diagnostic
(This special issue belongs to the Section Medical Research)
Therapeutic Effects of Natural Products on Human Diseases: 2nd Edition
edited by
submission deadline 27 Oct 2025 | 9 articles | Viewed by 16145 | Submission Open
Keywords: natural products; natural extracts; cancer; neurodegenerative diseases; immunological disorders; metabolic diseases; oriental medicine; microorganisms; algae; functional foods
(This special issue belongs to the Section Pharmaceutical Science)
Role of Machine and Deep Learning in Drug Screening
edited by and
submission deadline 29 Oct 2025 | Viewed by 491 | Submission Open
Keywords: machine learning in drug screening; deep learning in drug discovery; virtual screening; molecular docking and dynamics; personalized medicine
(This special issue belongs to the Section Pharmaceutical Science)
Soil–Plant–Microbe Interactions: The Role of Biostimulants and Agro-Environmental Implications
edited by Regina Gabilondo and
submission deadline 30 Oct 2025 | 3 articles | Viewed by 5158 | Submission Open
Keywords: soil– plant– microbe system; biostimulants; rhizosphere; fertilizers; availability of mineral nutrients; microfaunal grazing; protozoa; nematode; mycorrhizae; microbial loop
(This special issue belongs to the Section Plant Science)
Advances in Integrative Omics Data Analysis for Cancer Research
edited by , Jianli Dai and Guangyi Niu
submission deadline 30 Oct 2025 | 1 articles | Viewed by 3589 | Submission Open
Keywords: cancer research; omics; bioinformatics; translational medicine
(This special issue belongs to the Section Genetics and Genomics)
Advances in Dryland Agriculture Science
edited by and Hangyu Dong
submission deadline 30 Oct 2025 | 2 articles | Viewed by 1787 | Submission Open
Keywords: dry farming; climate smart agriculture; soil and water protection; conservation tillage; intercropping; crop rotation; saving irrigation
(This special issue belongs to the Section Plant Science)
Diagnostic Imaging in Colorectal Cancer
edited by and Chiara Zanon
submission deadline 30 Oct 2025 | 1 articles | Viewed by 1731 | Submission Open
Keywords: colorectal cancer; artificial intelligence; texture analysis; ultrasound; magnetic resonance imaging; PET/MRI
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Optogenetics and Light-Induced Processes in Synthetic Biology
edited by
submission deadline 30 Oct 2025 | Viewed by 648 | Submission Open
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Advances in Anesthesia and Critical Care
edited by
submission deadline 30 Oct 2025 | 1 articles | Viewed by 117 | Submission Open
Keywords: anesthesia; intensive care training; updates in anesthesia; machine learning
(This special issue belongs to the Section Medical Research)
Personalized Prevention and Treatment in Endocrinology, Diabetes and Metabolic Diseases
edited by Grigorios Panagiotou
submission deadline 31 Oct 2025 | 11 articles | Viewed by 28006 | Submission Open
Keywords: personalized medicine; precision prevention; multi-omics; obesity; diabetes and endocrinology
(This special issue belongs to the Section Medical Research)
Resistance Training Is Medicine submission deadline 31 Oct 2025 | 4 articles | Viewed by 14291 | Submission Open
Keywords: resistance training; resistance exercise; physical activity; sedentary behavior; strength training; chronic disease; risk factors; obesity; physical health
(This special issue belongs to the Section Epidemiology)
Algae—a Step Forward in the Sustainability of Resources: 2nd Edition submission deadline 31 Oct 2025 | 9 articles | Viewed by 11934 | Submission Open
Keywords: macroalgae; microalgae; cyanobacteria; bioactive compounds; biomass production; pharmaceuticals; nutraceuticals; cosmetics; food/feed; CO2 sequestrations; water treatment; IMTA; ecosystem services; biofuels; biopesticides; green extraction methods
(This special issue belongs to the Section Microbiology)
Physical Rehabilitation for Musculoskeletal Disorders
edited by You Gyoung Yi
submission deadline 31 Oct 2025 | 9 articles | Viewed by 9811 | Submission Open
Keywords: physical rehabilitation; musculoskeletal disorders; pain management; range of motion; muscle strengthening; mobility enhancement; physical therapy; manual therapy; AI in rehabilitation
(This special issue belongs to the Section Medical Research)
Ecotoxicity Effects of Metals and Microplastics on Aquatic Organisms
edited by Chiara Martino
submission deadline 31 Oct 2025 | 4 articles | Viewed by 4414 | Submission Open
Keywords: aquatic organisms; emerging contaminants; metals; microplastics; defense strategies; cell stress; heavy metals; environmental stress; pollution; ecotoxicology
(This special issue belongs to the Section Animal Science)
Recent Advances in Physiotherapy for Musculoskeletal submission deadline 31 Oct 2025 | 4 articles | Viewed by 3893 | Submission Open
Keywords: musculoskeletal rehabilitation; emerging technologies; virtual reality; artificial intelligence; inflammatory genetics; physiotherapy; sports medicine; functional recovery
(This special issue belongs to the Section Physiology and Pathology)
Coronary Artery Disease: Pathophysiological Mechanisms, Imaging Modalities and Therapeutic Implications
edited by Michele Russo and Filippo Luca Gurgoglione
submission deadline 31 Oct 2025 | 3 articles | Viewed by 3329 | Submission Open
Keywords: coronary artery disease; coronary atherosclerosis; atherosclerotic plaque progression; coronary imaging; cardiovascular risk factors and coronary atherosclerosis-associated diseases
(This special issue belongs to the Section Medical Research)
Unlocking New Biochemical Pathways: A Bridge for Drug Development in Human and Animal Diseases submission deadline 31 Oct 2025 | 1 articles | Viewed by 2889 | Submission Open
Keywords: drug discovery; omics sciences; veterinary sciences; oxidative stress; bioactive compounds; inflammation; cancer; neurodegeneration; cell death
(This special issue belongs to the Section Pharmaceutical Science)
Advances in Neuroimaging and Functional Brain Analysis
edited by Gianvincenzo Sparacia
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1984 | Submission Open
Keywords: magnetic resonance imaging; resting-state functional magnetic resonance imaging; connectomics; functional connectivity; brain networks; brain diseases assessment
(This special issue belongs to the Section Medical Research)
Advances and Applications of Sport Physiology: 2nd Edition
edited by and
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1330 | Submission Open
Keywords: sports medicine; strength and conditioning; diagnostics; sport injuries; performance analysis
(This special issue belongs to the Section Physiology and Pathology)
Bone and Cartilage Fractures: Types, Diagnosis, Complications, Prevention and Treatment
edited by Massimiliano Leigheb, Gabriele Colò and
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1318 | Submission Open
Keywords: fracture; traumatology; diagnosis; surgery; osteosynthesis; reduction; cartilage; chondral; lesion; injury; rehabilitation; complication
(This special issue belongs to the Section Medical Research)
Health Management of Farm Animals: Physiological and Pathological Aspects submission deadline 31 Oct 2025 | 2 articles | Viewed by 1039 | Submission Open
Keywords: cattle; small ruminants; pig; poultry; veterinary medicine; health; disease; welfare
(This special issue belongs to the Section Animal Science)
Molecular Muscle Adaptations Across the Lifespan
edited by S. Kyle Traivs and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 996 | Submission Open
Keywords: muscle tissue; muscle physiology; molecular pathways; therapeutics
(This special issue belongs to the Section Physiology and Pathology)
Gynecologic Oncology: Recent Advances and Future Perspectives
edited by Theodoros A. Panoskaltsis and
submission deadline 31 Oct 2025 | 1 articles | Viewed by 974 | Submission Open
Keywords: gynecologic cancer; gynecologic oncology; biomarkers in gynecology
(This special issue belongs to the Section Medical Research)
Orthopedic Disease Treatment and Management: Innovations, Challenges, and Future Directions
edited by Mihnea Ioan Gabriel Popa
submission deadline 31 Oct 2025 | 1 articles | Viewed by 970 | Submission Open
Keywords: orthopedic surgery; musculoskeletal regeneration; biomaterials and implants; minimally invasive techniques; periprosthetic joint infections; regenerative medicine; biomechanics and implant design; orthopedic trauma and reconstruction; rehabilitation and functional recovery; AI and robotics in orthopedics
(This special issue belongs to the Section Medical Research)
Pediatric Cardiology Frontiers: Innovations in Diagnosis and Treatment submission deadline 31 Oct 2025 | 1 articles | Viewed by 683 | Submission Open
Keywords: congenital heart disease; cardiovascular imaging; minimally invasive interventions; fetal cardiology; transcatheter therapies; artificial intelligence in cardiology; 3D echocardiography; cardiac MRI; personalized medicine; genetic heart disorders; heart failure in children; robotic-assisted surgery; cardiovascular biomarkers; electrophysiology in pediatrics; innovative surgical techniques; early diagnosis of heart disease; emerging therapies in cardiology
(This special issue belongs to the Section Medical Research)
Research on Gastrointestinal Cancer and Nutritional Health
edited by , Adam Mylonakis and Dimitrios Tsapralis
submission deadline 31 Oct 2025 | 1 articles | Viewed by 649 | Submission Open
Keywords: dietary patterns; gastrointestinal cancer; clinical nutrition; nutritional status; nutritional assessment; metabolism; gastric cancer; esophageal cancer; pancreatic cancer; colorectal cancer
(This special issue belongs to the Section Medical Research)
Diagnosis and Treatment of Orthopedic Diseases: Advancing Arthroscopy submission deadline 31 Oct 2025 | 1 articles | Viewed by 639 | Submission Open
Keywords: arthroscopy; knee; hip; shoulder; arthroscopic surgery
(This special issue belongs to the Section Medical Research)
The Management and Prognosis of Open-Angle Glaucoma
edited by
submission deadline 31 Oct 2025 | 2 articles | Viewed by 532 | Submission Open
Keywords: open-angle glaucoma; cataracts; visual impairment
(This special issue belongs to the Section Medical Research)
Microalgae and Their Biotechnological Potential
edited by , Yi Xin and Yuanxue Liang
submission deadline 31 Oct 2025 | Viewed by 508 | Submission Open
Keywords: microalgae; biofuels; bioproducts; lipid metabolism; synthetic biology; system engineering
(This special issue belongs to the Section Microbiology)
Opportunistic Infections in the Immunocompromised Patient
edited by and Luca Navarini
submission deadline 31 Oct 2025 | Viewed by 210 | Submission Open
Keywords: immunocompromised patients; opportunistic infections; infectious diseases; HIV; immunological mechanisms; epidemiology
(This special issue belongs to the Section Medical Research)
Advanced Research in Obstetrics and Gynecology
edited by Vasileios Pergialiotis
submission deadline 31 Oct 2025 | Viewed by 160 | Submission Open
Keywords: obstetrics; gynecology; gynecologic oncology
(This special issue belongs to the Section Medical Research)
Skin Care and Innovation from the Perspective of Molecular Dermatology submission deadline 31 Oct 2025 | Viewed by 153 | Submission Open
Keywords: molecular dermatology; personalised skincare; ageing; natural ingredients
(This special issue belongs to the Section Physiology and Pathology)
Metabolic Eye Diseases: From Tomography to Clinical Prediction submission deadline 31 Oct 2025 | Viewed by 123 | Submission Open
Keywords: metabolic eye diseases; ophthalmic tomography and imaging biomarkers; diabetic retinopathy and systemic metabolic disorders; mitochondrial dysfunction and optic neuropathies; corneal metabolic diseases and ocular surface disorders; artificial intelligence in clinical prediction of eye diseases; metabolic pathways and retinal degeneration; translational research in metabolic ophthalmology
(This special issue belongs to the Section Physiology and Pathology)
Natural Products for the Management of Acute and Chronic Kidney Disease
edited by Noori S. D. Al-Waili
submission deadline 31 Oct 2025 | Viewed by 119 | Submission Open
Keywords: kidney; diseases; management; natural products; proteinuria; bee products
(This special issue belongs to the Section Pharmaceutical Science)
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