Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Advances in Neuroimaging and Brain Functions: 2nd Edition submission deadline 30 May 2025 | 2 articles | Viewed by 6711 | Submission Open
Keywords: neuroimaging; brain functions; neurological diseases; humanities and social sciences; noninvasive methods; AI deep learning
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Applications of EEG in Neural Rehabilitation: 2nd Edition submission deadline 30 May 2025 | 2 articles | Viewed by 5514 | Submission Open
Keywords: neurorehabilitation; neuroplasticity; EEG; ERPs; qEEG; EEG mediated patient-therapist interaction; BCI; exoskeleton; cognitive rehabilitation; brain rewiring
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Ecology and Conservation of Small Mammals: Exploring Biodiversity, Climate Resilience, and Ecosystem Dynamics Through Small Mammal Monitoring and Research: 2nd Edition submission deadline 30 May 2025 | 3 articles | Viewed by 3878 | Submission Open
Keywords: small mammals; biodiversity; indicators; monitoring; assessment; communities
(This special issue belongs to the Section Diversity and Ecology)
Pain Management and Related Complications in the Orthopedics and Neurology
edited by Danilo Donati and
submission deadline 30 May 2025 | 1 articles | Viewed by 2376 | Submission Open
Keywords: pain management of the upper and lower limb; pain management of the spine; orthopaedic rehabilitation; prevention of fall risks prevention and management infections; muscle; tendon; and joint diseases; neurological impacts on musculoskeletal health
(This special issue belongs to the Section Physiology and Pathology)
Human Infertility and Reproductive Endocrinology: 2nd Edition
edited by
submission deadline 30 May 2025 | 2 articles | Viewed by 2316 | Submission Open
Keywords: infertility; reproduction; reproductive endocrinology; male infertility; female infertility
(This special issue belongs to the Section Reproductive and Developmental Biology)
Diagnostic Imaging in Colorectal Cancer
edited by and Chiara Zanon
submission deadline 30 May 2025 | 1 articles | Viewed by 1218 | Submission Open
Keywords: colorectal cancer; artificial intelligence; texture analysis; ultrasound; magnetic resonance imaging; PET/MRI
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Advancing Nanotechnology in Cancer Theranostics
edited by
submission deadline 30 May 2025 | 1 articles | Viewed by 1200 | Submission Open
Keywords: nanotechnology; cancer; nanoscale materials; nanoparticles; diagnostic accuracy; therapeutic efficacy; metastasis detection and prediction; targeted drug delivery; personalized cancer therapy
(This special issue belongs to the Section Medical Research)
Pharmacokinetic and Pharmacogenetic Approaches in Personalized Medicine
edited by and Giuliana Abbadessa
submission deadline 30 May 2025 | 1 articles | Viewed by 695 | Submission Open
Keywords: pharmacogenetics; pharmacokinetics; sex; gender; drugs; personalization
(This special issue belongs to the Section Pharmaceutical Science)
Microbial Diversity and Function in Aquatic Environments
edited by Xianglong Chen and
submission deadline 30 May 2025 | Viewed by 422 | Submission Open
Keywords: aquatic environment; microbial diversity and function; element biogeochemical cycle; interaction between microorganisms and aquatic environments; metaomic approaches
(This special issue belongs to the Section Microbiology)
Role of Mitochondria in the Pathophysiology of Cardiovascular Diseases
edited by Yuriana Oropeza-Almazán and Héctor Chapoy-Villanueva
submission deadline 30 May 2025 | Viewed by 404 | Submission Open
Keywords: cardiovascular diseases (CVDs); mitochondria; mitochondrial dysfunction; ATP production; mitochondrial fission; mitochondrial fusion; electron transport chain; oxidative phosphorylation; mitophagy; cardiac hypertrophy; myocardial infarction; IR injury; mitochondrial ROS; ROS signaling; ion homeostasis; cardiac arrhythmias
(This special issue belongs to the Section Physiology and Pathology)
3D Imaging and Facial Reconstruction
edited by Marios Papadakis
submission deadline 30 May 2025 | Viewed by 276 | Submission Open
Keywords: 3D imaging; facial plastic surgery; reconstructive surgery; virtual surgical planning; custom implants; preoperative planning; intraoperative navigation
(This special issue belongs to the Section Medical Research)
Advances in Vascular Health and Metabolism
edited by Ana Blazquez-Medela
submission deadline 30 May 2025 | Viewed by 191 | Submission Open
Keywords: cardiovascular; cardiometabolic disease; adipogenesis; atherosclerosis; obesity; overweight; peripheral artery disease
(This special issue belongs to the Section Medical Research)
Advances in Knee Osteoarthritis and Photobiomodulation Therapy submission deadline 30 May 2025 | Viewed by 161 | Submission Open
Keywords: knee osteoarthritis; light-emitting diode therapy; low-level laser therapy; high-intensity laser therapy; photobiomodulation therapy
(This special issue belongs to the Section Medical Research)
Cancer Genomics and Transcriptomics: Uncovering New Frontiers in Tumor Biology
edited by and Panagiotis Tsiakanikas
submission deadline 30 May 2025 | Viewed by 140 | Submission Open
Keywords: transcriptomic profiling; tumor heterogeneity; integrative omics; non-coding RNAs; oncogenes
(This special issue belongs to the Section Genetics and Genomics)
Strategies for Enchancing the Production in Plant
edited by , , Jie Huang and Xixi Liu
submission deadline 30 May 2025 | Viewed by 139 | Submission Open
Keywords: genetic improvement; biostimulants; nutrient management; synthetic biology
(This special issue belongs to the Section Plant Science)
Molecular Biomarkers in Inflammatory Disease
edited by Stelvio Tonello
submission deadline 30 May 2025 | Viewed by 133 | Submission Open
Keywords: cytokines; chemokines; and immune mediators as pharmacodynamic biomarkers; genomic and epigenomic contributions to drug response variability; proteomic and metabolomic profiling to guide pharmacotherapy in inflammation; biomarker-driven strategies for drug development and personalized treatment; mechanistic studies on drug– biomarker interactions and their clinical relevance; novel biomarkers for predicting adverse drug reactions in inflammatory diseases
(This special issue belongs to the Section Medical Research)
Sustainable Agroforestry: Molecular Strategies for Integrated Pest and Disease Management
edited by Gothandapani Sellamuthu and Kanakachari Mogilicherla
submission deadline 30 May 2025 | Viewed by 123 | Submission Open
Keywords: sustainable agroforestry; integrated pest management; genomics; transcriptomics; CRISPR technology; RNAi; plant– microbe interactions; biopesticides
(This special issue belongs to the Section Plant Science)
Vision Science and Optometry submission deadline 31 May 2025 | 7 articles | Viewed by 6372 | Submission Open
Keywords: clinical optometry; eye movements and binocular vision; aberrometry; accommodation; color vision; anterior and posterior poles; circadian light
(This special issue belongs to the Section Physiology and Pathology)
Exploring Enteric Glia: Implications for Gastrointestinal and Systemic Disorders
edited by Vladimir Grubišić
submission deadline 31 May 2025 | Viewed by 848 | Submission Open
Keywords: gut– brain axis; gut– liver axis; gut– pancreas axis; intestinal epithelial barrier function; intestinal vascular barrier function; myenteric plexus barrier; neuro– glia– immune interactions; metabolic disorders; neurodegenerative diseases; neurodevelopmental disorders
(This special issue belongs to the Section Physiology and Pathology)
Advances in Emergency and Critical Care Medicine
edited by
submission deadline 31 May 2025 | Viewed by 459 | Submission Open
Keywords: emergency medicine; critical care; trauma; infectious diseases; elderly
(This special issue belongs to the Section Medical Research)
Metabolic Research in Animal Nutrition submission deadline 31 May 2025 | Viewed by 212 | Submission Open
Keywords: nutrition; supplementation; microbiota; obesity; metabolic syndrome; metabolic disorders and diseases; hormonal factors; development and metabolism; metabolomics; nutrigenomics
(This special issue belongs to the Section Animal Science)
Microvascular and Macrovascular Response in Healthy and Critically Ill
edited by Andrius Pranskunas and
submission deadline 31 May 2025 | Viewed by 211 | Submission Open
Keywords: microcirculation; glycocalyx; peripheral perfusion; systemic hemodynamic; body temperature; dynamic maneuvers; remote ischemic conditioning; exercise; adaptation
(This special issue belongs to the Section Physiology and Pathology)
Topographic and Functional Anatomy of Musculoskeletal System: 2nd Edition submission deadline 31 May 2025 | Viewed by 210 | Submission Open
Keywords: muscle; bone; joint; peripheral nerve; motor innervation; proprioception; anatomical variant; radiologic imaging; development; comparative anatomy
(This special issue belongs to the Section Medical Research)
Advances in Novel Biomarkers and Emerging Immune/Targeted Therapies in Solid Tumors
edited by and Liang Lu
submission deadline 31 May 2025 | Viewed by 202 | Submission Open
Keywords: solid tumor; biomarker; molecular targets; tyrosine kinase inhibitors (TKIs); immune checkpoint inhibitors (ICIs); oncogenic driver mutation; acquired resistance; precision oncology; cancer; next-generation sequence
(This special issue belongs to the Section Medical Research)
Targeting Hormonal Regulation in Prostate Cancer
edited by Marília Figueira
submission deadline 31 May 2025 | Viewed by 193 | Submission Open
Keywords: prostate cancer; castrate resistant prostate cancer (CRPC); metastatic prostate cancer; estrogens; estrogen receptors; drug resistance
(This special issue belongs to the Section Medical Research)
Atherosclerosis: Pathogenesis, Clinical Advances and Future Perspectives submission deadline 31 May 2025 | Viewed by 169 | Submission Open
Keywords: atherosclerosis; cardiovascular risk; hypercholesterolemia; hypertension; inflammation; cardiovascular prevention
(This special issue belongs to the Section Medical Research)
Pediatric Ophthalmic Pathology—Integrating Clinical and Basic Research
edited by and Brenda L. Bohnsack
submission deadline 31 May 2025 | Viewed by 142 | Submission Open
Keywords: congenital eye anomalies; anterior segment disorders; genetic eye disorders; pediatric eye conditions; pediatric ophthalmology
(This special issue belongs to the Section Physiology and Pathology)
Cell Asymmetry and Polarity: Guiding Cellular Behavior and Development: Second Edition
edited by
submission deadline 31 May 2025 | Viewed by 123 | Submission Open
Keywords: cell asymmetry; cell polarity; tissue morphogenesis; planar cell polarity (PCP) pathway; Wnt pathway; therapeutic implications
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Global Developments in Musculoskeletal Health Research and Practice
edited by Stefanie Krauth, and John A. Hammond
submission deadline 31 May 2025 | Viewed by 114 | Submission Open
Keywords: musculoskeletal diseases; therapeutics; epidemiological studies
(This special issue belongs to the Section Epidemiology)
Therapeutic Approaches of Marine Natural Products in Health and Disease
edited by Thilina U. Jayawardena and D. P. Nagahawatta
submission deadline 31 May 2025 | Viewed by 91 | Submission Open
Keywords: marine natural products; bioactive compounds; drug discovery; therapeutic applications
(This special issue belongs to the Section Pharmaceutical Science)
Gut Microbes Associating with the Host
edited by and
submission deadline 10 Jun 2025 | Viewed by 540 | Submission Open
Keywords: gut microbes; microbiome; animals; nutrition
(This special issue belongs to the Section Microbiology)
Antibiotic Resistance in Biofilm: 2nd Edition
edited by
submission deadline 16 Jun 2025 | 4 articles | Viewed by 5418 | Submission Open
Keywords: biofilm; food industry; antimicrobial resistance; antibiotic resistance gene transfer; antibiofilm activity; control strategies
(This special issue belongs to the Section Microbiology)
Advances in the Treatment of Pulmonary Hypertension and Pulmonary Embolism submission deadline 16 Jun 2025 | 1 articles | Viewed by 987 | Submission Open
Keywords: pulmonary hypertension; pulmonary embolism; therapy; cardiac imaging; artificial intelligence
(This special issue belongs to the Section Medical Research)
New Restorative Technologies in the Management and Characterization Techniques of the Hard and Soft Tissues of Oral Cavity
edited by Ilaria Giovannacci, Silvia Pizzi and Careri Maria
submission deadline 20 Jun 2025 | Viewed by 98 | Submission Open
Keywords: microscopy analysis imaging; jaw bone; oral mucosa; autofluorescence; adhesive dentistry; oral surgery; regenerative medicine; lasers
(This special issue belongs to the Section Medical Research)
Nutrition, Exercise and Stress
edited by Maleah Holland-Winkler
submission deadline 25 Jun 2025 | Viewed by 111 | Submission Open
Keywords: nutrition; exercise; stress
(This special issue belongs to the Section Physiology and Pathology)
Microvascular Dynamics: Insights and Applications
edited by and Friedrich Jung
submission deadline 26 Jun 2025 | 4 articles | Viewed by 9229 | Submission Open
Keywords: microvessels; dynamics; velocity; flow; rheology; in vitro; animals; humans; biomarkers; imaging; simulations; models; preclinical; clinical
(This special issue belongs to the Section Physiology and Pathology)
Advances in Research on Motor Deficits Caused by Neurological Disorders: From Mechanism to Treatment
edited by
submission deadline 26 Jun 2025 | Viewed by 376 | Submission Open
Keywords: neurological disorders; neurodegenerative diseases; brain injury; spinal cord injury; stroke; cerebral palsy; peripheral nerve injury; paralysis; spasticity; contracture; muscle weakness; postural asymmetry; gate pattern changes; uncontrolled movements
(This special issue belongs to the Section Medical Research)
Innovative Strategies in Insecticide Resistance and Sustainable Pest Management
edited by Chengwang Sheng, and
submission deadline 27 Jun 2025 | 1 articles | Viewed by 1176 | Submission Open
Keywords: insecticide resistance; sustainable pest management; integrated pest management; bioinsecticides; physical pest control; gene editing; insect sterilization; transgenic technology; molecular targets for pesticides
(This special issue belongs to the Section Animal Science)
From Stem Cells to Embryos, Congenital Anomalies and Epidemiology
edited by , Soultana Meditskou and
submission deadline 30 Jun 2025 | 6 articles | Viewed by 13552 | Submission Open
Keywords: stem cell research; human embryonic development; birth defects epidemiology; birth defects prevalence; maternal and fetal medicine; congenital anomalies prevention; ultrasound evaluation; pre-birth assessment; prenatal screening; healthcare
(This special issue belongs to the Section Epidemiology)
Retinal Diseases: From Molecular Mechanisms to Therapeutics
edited by
submission deadline 30 Jun 2025 | 7 articles | Viewed by 12260 | Submission Open
Keywords: retinal disease; inflammatory disease; genetic diseases; ocular drug development
(This special issue belongs to the Section Physiology and Pathology)
New Horizons of Adipose Tissue Disorders: From Hormonal Issues to Loose Connective Disease submission deadline 30 Jun 2025 | 3 articles | Viewed by 10791 | Submission Open
Keywords: adipose tissue; lipedema; lymphedema; obesity; matrix; vascular and lymphatic disorder; connective tissue diseases; dysbiosis; inflammation; pain
(This special issue belongs to the Section Physiology and Pathology)
New Insights into Allergic Eye Diseases submission deadline 30 Jun 2025 | 2 articles | Viewed by 9665 | Submission Open
Keywords: allergy; IgE; IL-4; IL-5; IL-13; TNF-alpha; mast cells; eosinophils; Th1 cells; Th2 cells; therapeutics; immunopathogenesis; immunopathology; conjunctivitis; keratoconjunctivitis
(This special issue belongs to the Section Medical Research)
Nutritional Supplements and Cardiovascular Function in Athletes and Sedentary People submission deadline 30 Jun 2025 | 3 articles | Viewed by 4057 | Submission Open
Keywords: athletes; sedentary; eating habits; nutrition; endothelium; microcirculation; vascular function; nutritional supplements; oxidative stress; antioxidants; NRF2-signaling pathway; functional food; cardiovascular function; prevention; physical activity
(This special issue belongs to the Section Medical Research)
Advances in Endoscopic, Surgical, and Interventional Radiological Management of Gastrointestinal Diseases
edited by
submission deadline 30 Jun 2025 | 3 articles | Viewed by 3618 | Submission Open
Keywords: gastrointestinal disease; endoscopic cystogastrostomy; endoscopic biliary prosthesis; endoscopic pancreatic prosthesis; endoscopic necrosectomy; esophagectomy; gastrectomy; bowel resection; colectomy; pancreatectomy; hepatectomy; liver transplantation; gastroenterology; surgery; interventional radiology
(This special issue belongs to the Section Medical Research)
Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders
edited by , , Maria Chiara Vulpiani, Maria Cristina D'Agostino, Larisa Ryskalin and Federica Fulceri
submission deadline 30 Jun 2025 | 2 articles | Viewed by 3191 | Submission Open
Keywords: shockwave; tissue regeneration; pain; functional recovery and healing; physical medicine and rehabilitation; clinical applications; imaging
(This special issue belongs to the Section Medical Research)
Eye Diseases: Diagnosis and Treatment, 3rd Edition
edited by and Laura De Diego-García
submission deadline 30 Jun 2025 | 4 articles | Viewed by 2297 | Submission Open
Keywords: ocular treatment; ocular diseases; retina; anterior eye; posterior eye; ocular biomarkers
(This special issue belongs to the Section Medical Research)
Revolutionizing Neuroregeneration
edited by
submission deadline 30 Jun 2025 | 2 articles | Viewed by 2017 | Submission Open
Keywords: Alzheimer’ s disease; Parkinson’ s disease; neuroregeneration; stroke; regenerative therapy
(This special issue belongs to the Section Cell Biology and Tissue Engineering)
Physiological Responses of Plants Under Abiotic Stresses
edited by Dawei Shi
submission deadline 30 Jun 2025 | 2 articles | Viewed by 1987 | Submission Open
Keywords: crops; woody plants; horticultural plants; physiological responses; abiotic stresses; photosynthesis
(This special issue belongs to the Section Plant Science)
Musculoskeletal Pain and Disorders: Diagnosis, Treatment and Management submission deadline 30 Jun 2025 | 1 articles | Viewed by 1929 | Submission Open
Keywords: pain; connective tissue; musculoskeletal disorders; fascia; muscles; tendons; ligaments
(This special issue belongs to the Section Physiology and Pathology)
Innovative Applications of Extracellular Vesicles: From Diagnostics to Drug Delivery
edited by Alessandra Lo Cicero
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1831 | Submission Open
Keywords: extracellular vesicles; exosomes; cancer; cardiovascular diseases; neurodegenerative diseases; biomarkers; diagnostics; cell-cell communication; drug delivery; therapeutics
(This special issue belongs to the Section Physiology and Pathology)
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