Application of Mass Spectrometry-Based Multi-Omics in Biomedical Research
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 26 June 2026 | Viewed by 539
Special Issue Editors
Interests: mass spectrometry-based multi-omics applications
Special Issue Information
Dear Colleagues,
Mass spectrometry (MS) has long been a cornerstone of molecular analysis, but its full potential is now being realized through integrated, multi-omics strategies that combine proteomics, metabolomics, lipidomics, and mass spectrometry imaging (MSI).
Proteomics provides insight into protein abundance and post-translational modifications, while metabolomics and lipidomics capture metabolic states that reflect cellular function and phenotype. MSI adds a powerful spatial dimension, localizing molecules directly within tissues and revealing heterogeneity that bulk analyses overlook. When integrated, these platforms enable researchers not only to identify molecular changes but also to place them in a functional and anatomical context, paving the way for breakthroughs in precision medicine, oncology, neurology, cardiovascular research, and drug development.
This Special Issue seeks research articles, reviews, and technical advances that leverage MS-based multi-omics in biomedical research. Submissions may include the following:
- Integrated omics workflows combining two or more MS-based modalities;
- Spatial multi-omics and MSI applications in disease biology or drug delivery;
- Novel sample preparation, acquisition strategies, or data analysis pipelines;
- Translational studies identifying biomarkers or therapeutic targets;
- Computational and statistical methods for multi-omics data integration.
By bringing together leaders across analytical chemistry, bioinformatics, and translational science, this Special Issue aims to highlight innovations that expand the capabilities and impact of MS-based multi-omics in modern biomedical research.
Prof. Dr. Young Ah Goo
Guest Editor
Dr. Byoung-Kyu Cho
Co-Guest Editor
Manuscript Submission Information
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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Life is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- mass spectrometry
- multi-omics
- proteomics
- metabolomics
- lipidomics
- mass spectrometry imaging (MSI)
- biomarker discovery
- translational research
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