Application of Mass Spectrometry-Based Multi-Omics in Biomedical Research
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Medical Research".
Deadline for manuscript submissions: 26 June 2026 | Viewed by 12
Special Issue Editor
Special Issue Information
Dear Colleagues,
Mass spectrometry (MS) has long been a cornerstone of molecular analysis, but its full potential is now being realized through integrated, multi-omics strategies that combine proteomics, metabolomics, lipidomics, and mass spectrometry imaging (MSI).
Proteomics provides insight into protein abundance and post-translational modifications, while metabolomics and lipidomics capture metabolic states that reflect cellular function and phenotype. MSI adds a powerful spatial dimension, localizing molecules directly within tissues and revealing heterogeneity that bulk analyses overlook. When integrated, these platforms enable researchers not only to identify molecular changes but also to place them in a functional and anatomical context, paving the way for breakthroughs in precision medicine, oncology, neurology, cardiovascular research, and drug development.
This Special Issue seeks research articles, reviews, and technical advances that leverage MS-based multi-omics in biomedical research. Submissions may include the following:
- Integrated omics workflows combining two or more MS-based modalities;
- Spatial multi-omics and MSI applications in disease biology or drug delivery;
- Novel sample preparation, acquisition strategies, or data analysis pipelines;
- Translational studies identifying biomarkers or therapeutic targets;
- Computational and statistical methods for multi-omics data integration.
By bringing together leaders across analytical chemistry, bioinformatics, and translational science, this Special Issue aims to highlight innovations that expand the capabilities and impact of MS-based multi-omics in modern biomedical research.
Prof. Dr. Young Ah Goo
Guest Editor
Manuscript Submission Information
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Keywords
- mass spectrometry
- multi-omics
- proteomics
- metabolomics
- lipidomics
- mass spectrometry imaging (MSI)
- biomarker discovery
- translational research
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