Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advancements in Postoperative Management of Patients After Surgery
edited by , , and Alessandro Cappellani
submission deadline 30 Sep 2025 | 3 articles | Viewed by 3160 | Submission Open
Keywords: surgery; ERAS; postoperative management; recovery; pain
(This special issue belongs to the Section Medical Research)
Multi-Omics for Diagnosing Diseases: Bioinformatics Approaches and Integrative Data Analyses submission deadline 30 Sep 2025 | 1 articles | Viewed by 1397 | Submission Open
Keywords: bioinformatics; computer hardware; software; and methods; first-/second-/third-generation sequencing; clinical genomics; mendelian diseases; whole-exome sequencing; evolutionary and comparative genomics; whole-genome sequencing; multi-omics; microbiome diseases
(This special issue belongs to the Section Genetics and Genomics)
Skin Diseases and Dermatologic Comorbidities
edited by Alessia Paganelli, and
submission deadline 30 Sep 2025 | 1 articles | Viewed by 639 | Submission Open
Keywords: skin diseases; dermatologic comorbidities; metabolic impairment; autoimmunity; cytokines; serum markers
(This special issue belongs to the Section Physiology and Pathology)
Advances in Livestock Breeding, Nutrition and Metabolism
edited by
submission deadline 30 Sep 2025 | Viewed by 519 | Submission Open
Keywords: genetic selection; livestock breeding; genome editing; animal nutrition; precision feeding; nutritional additives; feed conversion; metabolism; animal health; sustainability
(This special issue belongs to the Section Animal Science)
Enhancements in Screening Pathways for Early Detection of Lung Cancer submission deadline 30 Sep 2025 | 1 articles | Viewed by 496 | Submission Open
Keywords: lung cancer screening; early diagnosis; multidisciplinary pathways; liquid biopsy; exhaled breath condensate; molecular imaging; sub-lobar resection; artificial intelligence
(This special issue belongs to the Section Medical Research)
Acari: Biodiversity, Biogeography and Taxonomy Studies
edited by Pavel B. Klimov
submission deadline 30 Sep 2025 | Viewed by 480 | Submission Open
Keywords: phylogenetics; systematics; evolution and co-evolution; biodiversity; ecology; host associations; role of mites in agriculture and medicine
(This special issue belongs to the Section Animal Science)
New Insights into Athlete Physiology submission deadline 30 Sep 2025 | Viewed by 312 | Submission Open
Keywords: sport physiology; physical performance; injury prevention; cognition; artificial intelligence; dose– response relationship
(This special issue belongs to the Section Physiology and Pathology)
From Pathophysiology to Pathology—an Update on Diabetic Kidney Disease
edited by Sharma Prabhakar
submission deadline 30 Sep 2025 | Viewed by 308 | Submission Open
Keywords: diabetic kidney disease; epithelial– mesenchymal transition; renin– angiotensin– aldosterone system; sodium glucose transporter 2; albuminuria
(This special issue belongs to the Section Physiology and Pathology)
Precision Therapies in Cancer: Advancements and Future Directions
edited by and Krushna Chandra Hembram
submission deadline 30 Sep 2025 | Viewed by 305 | Submission Open
Keywords: precision oncology; cancer theragnostic; molecular targeting; immunotherapy
(This special issue belongs to the Section Medical Research)
Natural Substances in Nutrition and Health of Animals: 2nd Edition submission deadline 30 Sep 2025 | 1 articles | Viewed by 265 | Submission Open
Keywords: natural products; organic acids; probiotics; prebiotics; and synbiotics; plant extracts; animal nutrition; animal physiology; animal embryology; animal reproduction; animal models
(This special issue belongs to the Section Animal Science)
New Developments in Mycology submission deadline 30 Sep 2025 | Viewed by 225 | Submission Open
Keywords: fungal diversity; population genetics; phylogeography; mycorrhizae; biotechnology
(This special issue belongs to the Section Microbiology)
Cardiorenal Disease: Pathogenesis, Diagnosis, and Treatments
edited by Pedro Caravaca-Pérez and Jose Jesus Broseta
submission deadline 30 Sep 2025 | Viewed by 170 | Submission Open
Keywords: heart failure; kidney disease; cardiorenal syndrome; diagnosis; treatment
(This special issue belongs to the Section Medical Research)
An Update on Diabetic Kidney Disease: Epidemiology, Diagnosis, Treatment
edited by Sharma Prabhakar
submission deadline 30 Sep 2025 | Viewed by 168 | Submission Open
Keywords: diabetic kidney disease; epithelial– mesenchymal transition; renin– angiotensin– aldosterone system sodium glucose transporter 2; albuminuria
(This special issue belongs to the Section Medical Research)
Testicular and Penile Disorders: Reproductive, Pathophysiological, Diagnostic and Therapeutic Insights
edited by and Yu-Ching Wen
submission deadline 30 Sep 2025 | Viewed by 158 | Submission Open
Keywords: testicular and Penile Disorders; testicle; physiology; infertility
(This special issue belongs to the Section Physiology and Pathology)
2nd Edition—Food Microbiological Contamination submission deadline 30 Sep 2025 | Viewed by 139 | Submission Open
Keywords: food safety; food microbiology; foodborne pathogens; food spoilage; food quality; food contamination; microbiological hazards; natural antimicrobials
(This special issue belongs to the Section Microbiology)
Space Medicine Advancements: From Human Health to Biomedical System Design
edited by Jiwoon Park and
submission deadline 30 Sep 2025 | Viewed by 137 | Submission Open
Keywords: biomedical research in extreme environments including space; effects of gravity and radiation on biological systems; multi-omics studies on astronauts and experimental models; spaceflight analogs for disease modeling and mechanistic studies (in vitro and in vivo models); computational models for astronaut health and risk assessment (simulations and AI models); mitigation of spaceflight-induced pathophysiology and health risks; development of tools; biomarkers; and interventions for remote monitoring and the implementation of countermeasures to safeguard human health; lfe support systems and biotechnology solutions for space explorations
(This special issue belongs to the Section Medical Research)
Synthetic Genetic Elements, Devices, and Systems: 2nd Edition
edited by and
submission deadline 30 Sep 2025 | Viewed by 119 | Submission Open
Keywords: synthetic biology; synthetic genetic elements/parts; biobricks; artificial gene synthesis; biocomputing; directed evolution; metabolic engineering/cell factory; optogenetics; genetic code expansion; xenobiology
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Advances in Intensive Care Medicine
edited by
submission deadline 30 Sep 2025 | Viewed by 114 | Submission Open
Keywords: machine learning; critical care; intensive care; ARDS; mechanical ventilation; personalized medicine; advances
(This special issue belongs to the Section Medical Research)
Advances in Microvascular Research: 2nd Edition submission deadline 30 Sep 2025 | Viewed by 102 | Submission Open
Keywords: microvascular injury; microvascular dysfunction; microcirculation; vascular inflammation; hypertension; cardiovascular diseases
(This special issue belongs to the Section Physiology and Pathology)
Recent Advances in Vascular Biology and Chronic Kidney Disease (CKD)
edited by
submission deadline 30 Sep 2025 | Viewed by 101 | Submission Open
Keywords: chronic kidney disease; vascular dysfunction; endothelial cells
(This special issue belongs to the Section Medical Research)
Updates on Cancer Immunology and Immunotherapy
edited by Parnian Jabbari
submission deadline 30 Sep 2025 | Viewed by 94 | Submission Open
Keywords: cancer immunology; immunotherapy; immune checkpoints; tumor microenvironment; chimeric antigen receptor T-cell (CAR-T) therapy; cancer vaccines; immune evasion; tumor immunity; personalized immunotherapy; immune oncology; combination therapy; immune-related adverse events; neoantigens; adoptive cell transfer; oncolytic viruses; targeted immunotherapy; tumor-associated antigens; cancer immunosurveillance; resistance mechanisms; clinical trials in immunotherapy
(This special issue belongs to the Section Medical Research)
Research Progress of Cultivation of Edible Fungi: 2nd Edition
edited by Yajie Zou
submission deadline 30 Sep 2025 | Viewed by 91 | Submission Open
Keywords: edible fungi; cultivation; domesticate; substrate; biological efficiency; nutritional properties; functional compounds; sustainability; commercialization; emerging species
(This special issue belongs to the Section Microbiology)
Computational Approaches in Breast Cancer Diagnosis and Prognosis
edited by Elham Pashaei and
submission deadline 30 Sep 2025 | Viewed by 90 | Submission Open
Keywords: bioinformatics; machine learning; artificial intelligence; breast cancer
(This special issue belongs to the Section Physiology and Pathology)
Autoimmune Disorders: From Pathophysiology to Therapeutics
edited by and Chiara Mura
submission deadline 30 Sep 2025 | Viewed by 88 | Submission Open
Keywords: autoimmunity; autoimmune diseases; polyglandular autoimmune syndromes; thyroid autoimmune disease; type 1 diabetes
(This special issue belongs to the Section Physiology and Pathology)
Advances in Congenital Diaphragmatic Hernia: From Clinical Features to Management
edited by Przemysław Kosinski
submission deadline 30 Sep 2025 | Viewed by 72 | Submission Open
Keywords: congenital diaphragmatic hernia; prenatal diagnosis; fetal interventions; neonatal management; pulmonary hypoplasia; surgical techniques; imaging techniques; genetic testing; FETO; comprehensive care protocols  
(This special issue belongs to the Section Medical Research)
Cell-Free DNA as a Biomarker in Metabolic Diseases
edited by
submission deadline 20 Oct 2025 | Viewed by 79 | Submission Open
Keywords: cell-free DNA (cfDNA); liquid biopsy; metabolic diseases; obesity; type 2 diabetes; non-alcoholic fatty liver disease (NAFLD); methylation; mutations
(This special issue belongs to the Section Medical Research)
New Insights into Diagnosis and Therapeutic Strategies for Chronic Liver Diseases
edited by
submission deadline 20 Oct 2025 | Viewed by 63 | Submission Open
Keywords: chronic liver disease; metabolic dysfunction-associated steatotic liver disease (MASLD); metabolic dysfunction-associated steatohepatitis (MASH); drug-induced liver injury (DILI); hepatocellular carcinoma; biomarkers of liver fibrosis; imaging of liver fibrosis; CEUS; novel therapeutic strategies for CLDs
(This special issue belongs to the Section Medical Research)
Sensitization via Skin Exposure
edited by
submission deadline 20 Oct 2025 | Viewed by 25 | Submission Open
Keywords: contact dermatitis; patch test; epidemiology; occupation; prevention
Diversity and Evolution of Pathogenic Viruses
edited by
submission deadline 20 Oct 2025 | Viewed by 21 | Submission Open
Keywords: pathogenic viruses; biologic diversity; evolution
(This special issue belongs to the Section Medical Research)
Cancer Epidemiology
edited by Daniela-Cristina Stefan and Honoré K. Mitonga
submission deadline 24 Oct 2025 | 4 articles | Viewed by 4405 | Submission Open
Keywords: cancer disparities; specific populations; methodological advances; cancer trends; cancer causes; prevention strategies
(This special issue belongs to the Section Epidemiology)
Dive into Myopia
edited by
submission deadline 24 Oct 2025 | Viewed by 121 | Submission Open
Keywords: myopia; hyperopia; myopia control; axial length; axial length retardation; axial length elongation; myopia complications; refraction measurement; atropine; rebound effect; orthokeratology; missight; defocus incorporated multiple segments (DIMSs); highly aspherical lenslets (HALs); red light; repeated low-level red light (RLRL) therapy; enhance myopia control; customized myopia control; peripheral refraction; peripheral myopia; refractive surgery; PRK; LASIK; smile; contact lens; spectacles
(This special issue belongs to the Section Medical Research)
Neuroimaging and Integrative Analyses in Psychiatry and Addictive Disorders
edited by Arkadiusz Komorowski
submission deadline 25 Oct 2025 | Viewed by 118 | Submission Open
Keywords: psychiatry; neuroimaging; forensic psychiatry; fMRI; PET; EEG; addiction; substance use disorders (SUD); psychotherapy; treatment-resistant depression (TRD); attention deficit hyperactivity disorder (ADHD)
(This special issue belongs to the Section Physiology and Pathology)
Laparoscopy and Treatment: An All-Encompassing Solution for Surgeons
edited by Niculae Iordache and Claudiu-Octavian Ungureanu
submission deadline 26 Oct 2025 | 1 articles | Viewed by 653 | Submission Open
Keywords: oncological; staging laparoscopy; tool; radical surgery; diagnostic
(This special issue belongs to the Section Medical Research)
Therapeutic Effects of Natural Products on Human Diseases: 2nd Edition
edited by
submission deadline 27 Oct 2025 | 8 articles | Viewed by 12695 | Submission Open
Keywords: natural products; natural extracts; cancer; neurodegenerative diseases; immunological disorders; metabolic diseases; oriental medicine; microorganisms; algae; functional foods
(This special issue belongs to the Section Pharmaceutical Science)
Role of Machine and Deep Learning in Drug Screening
edited by and
submission deadline 29 Oct 2025 | Viewed by 442 | Submission Open
Keywords: machine learning in drug screening; deep learning in drug discovery; virtual screening; molecular docking and dynamics; personalized medicine
(This special issue belongs to the Section Pharmaceutical Science)
Soil–Plant–Microbe Interactions: The Role of Biostimulants and Agro-Environmental Implications
edited by Regina Gabilondo and
submission deadline 30 Oct 2025 | 3 articles | Viewed by 4181 | Submission Open
Keywords: soil– plant– microbe system; biostimulants; rhizosphere; fertilizers; availability of mineral nutrients; microfaunal grazing; protozoa; nematode; mycorrhizae; microbial loop
(This special issue belongs to the Section Plant Science)
Advances in Integrative Omics Data Analysis for Cancer Research
edited by , Jianli Dai and Guangyi Niu
submission deadline 30 Oct 2025 | 1 articles | Viewed by 2833 | Submission Open
Keywords: cancer research; omics; bioinformatics; translational medicine
(This special issue belongs to the Section Genetics and Genomics)
Advances in Dryland Agriculture Science
edited by and Hangyu Dong
submission deadline 30 Oct 2025 | 2 articles | Viewed by 1555 | Submission Open
Keywords: dry farming; climate smart agriculture; soil and water protection; conservation tillage; intercropping; crop rotation; saving irrigation
(This special issue belongs to the Section Plant Science)
Optogenetics and Light-Induced Processes in Synthetic Biology
edited by
submission deadline 30 Oct 2025 | Viewed by 599 | Submission Open
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Advances in Anesthesia and Critical Care
edited by
submission deadline 30 Oct 2025 | Viewed by 55 | Submission Open
Keywords: anesthesia; intensive care training; updates in anesthesia; machine learning
(This special issue belongs to the Section Medical Research)
Resistance Training Is Medicine submission deadline 31 Oct 2025 | 4 articles | Viewed by 10537 | Submission Open
Keywords: resistance training; resistance exercise; physical activity; sedentary behavior; strength training; chronic disease; risk factors; obesity; physical health
(This special issue belongs to the Section Epidemiology)
Algae—a Step Forward in the Sustainability of Resources: 2nd Edition submission deadline 31 Oct 2025 | 7 articles | Viewed by 8605 | Submission Open
Keywords: macroalgae; microalgae; cyanobacteria; bioactive compounds; biomass production; pharmaceuticals; nutraceuticals; cosmetics; food/feed; CO2 sequestrations; water treatment; IMTA; ecosystem services; biofuels; biopesticides; green extraction methods
(This special issue belongs to the Section Microbiology)
Physical Rehabilitation for Musculoskeletal Disorders
edited by You Gyoung Yi
submission deadline 31 Oct 2025 | 5 articles | Viewed by 6813 | Submission Open
Keywords: physical rehabilitation; musculoskeletal disorders; pain management; range of motion; muscle strengthening; mobility enhancement; physical therapy; manual therapy; AI in rehabilitation
(This special issue belongs to the Section Medical Research)
Ecotoxicity Effects of Metals and Microplastics on Aquatic Organisms
edited by Chiara Martino
submission deadline 31 Oct 2025 | 4 articles | Viewed by 3966 | Submission Open
Keywords: aquatic organisms; emerging contaminants; metals; microplastics; defense strategies; cell stress; heavy metals; environmental stress; pollution; ecotoxicology
(This special issue belongs to the Section Animal Science)
Unlocking New Biochemical Pathways: A Bridge for Drug Development in Human and Animal Diseases submission deadline 31 Oct 2025 | 1 articles | Viewed by 2602 | Submission Open
Keywords: drug discovery; omics sciences; veterinary sciences; oxidative stress; bioactive compounds; inflammation; cancer; neurodegeneration; cell death
(This special issue belongs to the Section Pharmaceutical Science)
Recent Advances in Physiotherapy for Musculoskeletal submission deadline 31 Oct 2025 | 3 articles | Viewed by 2363 | Submission Open
Keywords: musculoskeletal rehabilitation; emerging technologies; virtual reality; artificial intelligence; inflammatory genetics; physiotherapy; sports medicine; functional recovery
(This special issue belongs to the Section Physiology and Pathology)
Coronary Artery Disease: Pathophysiological Mechanisms, Imaging Modalities and Therapeutic Implications
edited by Michele Russo and Filippo Luca Gurgoglione
submission deadline 31 Oct 2025 | 3 articles | Viewed by 2130 | Submission Open
Keywords: coronary artery disease; coronary atherosclerosis; atherosclerotic plaque progression; coronary imaging; cardiovascular risk factors and coronary atherosclerosis-associated diseases
(This special issue belongs to the Section Medical Research)
Advances in Neuroimaging and Functional Brain Analysis
edited by Gianvincenzo Sparacia
submission deadline 31 Oct 2025 | 1 articles | Viewed by 1810 | Submission Open
Keywords: magnetic resonance imaging; resting-state functional magnetic resonance imaging; connectomics; functional connectivity; brain networks; brain diseases assessment
(This special issue belongs to the Section Medical Research)
Bone and Cartilage Fractures: Types, Diagnosis, Complications, Prevention and Treatment
edited by Massimiliano Leigheb, Gabriele Colò and
submission deadline 31 Oct 2025 | 2 articles | Viewed by 933 | Submission Open
Keywords: fracture; traumatology; diagnosis; surgery; osteosynthesis; reduction; cartilage; chondral; lesion; injury; rehabilitation; complication
(This special issue belongs to the Section Medical Research)
Gynecologic Oncology: Recent Advances and Future Perspectives
edited by Theodoros A. Panoskaltsis and
submission deadline 31 Oct 2025 | Viewed by 576 | Submission Open
Keywords: gynecologic cancer; gynecologic oncology; biomarkers in gynecology
(This special issue belongs to the Section Medical Research)
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