Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Impact of Circulating Ketones on Physiology
edited by Maleah Winkler
submission deadline 30 Oct 2024 | Viewed by 67 | Submission Open
Keywords: ketones; ketone supplementation; beta-hydroxybutyrate; ketogenic diet; fasting
(This special issue belongs to the Section Physiology and Pathology)
Recent Advances in Functional Genomics
edited by Katerina R. Katsani and
submission deadline 30 Oct 2024 | 1 articles | Viewed by 61 | Submission Open
Keywords: chromatin profiling; CRISPR screens; crop genomics; epigenome editing; epigenomics; interactomes; metagenomics; pharmacogenomics; phenomics
(This special issue belongs to the Section Genetics and Genomics)
Advances in the Treatment of Pulmonary Hypertension and Pulmonary Embolism submission deadline 30 Oct 2024 | Viewed by 48 | Submission Open
Keywords: pulmonary hypertension; pulmonary embolism; therapy; cardiac imaging; artificial intelligence
(This special issue belongs to the Section Medical Research)
New Insights into Breast Cancer: Current Controversies and Future Perspectives
edited by , Angela Bucaro and Flavia de Lauretis
submission deadline 30 Oct 2024 | Viewed by 47 | Submission Open
Keywords: breast cancer treatment; oncoplastic surgery; conservative mastectomy; breast reconstruction; sentinel node biopsy; chemotherapy; radiotherapy; integrated therapies
(This special issue belongs to the Section Medical Research)
Advances in Research in Biocatalysis: 2nd Edition
edited by and
submission deadline 30 Oct 2024 | Viewed by 22 | Submission Open
Keywords: biochemical; biomedical; biomaterials; biocatalysis; biodegradation; biofuels; bioplastics; directed evolution of enzymes; environmental remediation
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
Current Research on Dermatology: Pathology, Clinical Manifestation, Investigation and Therapy: 2nd Edition submission deadline 31 Oct 2024 | 13 articles | Viewed by 16662 | Submission Open
Keywords: demodex; endosymbionts; cutaneous microbiome; integrative medicine; optical coherence tomography; dermoscopy; confocal microscopy; cutaneous comorbidities keyword; inflammatory diseases; hair; skin cancer; comorbidities; skin surgery
(This special issue belongs to the Section Physiology and Pathology)
Mechanism, Diagnostic and Therapeutic Novelties in Dermatology: 2nd Edition submission deadline 31 Oct 2024 | 4 articles | Viewed by 3181 | Submission Open
Keywords: physiopathology; skin sonography; dermoscopy; innovation; confocal microscopy; biological treatment; psoriasis; atopic dermatitis; immune-mediated diseases; urticaria; laser CO2
(This special issue belongs to the Section Medical Research)
Trauma and Emergency: Beyond Damage Control Surgery: 2nd Edition
edited by , and Matteo Zanchetta
submission deadline 31 Oct 2024 | 2 articles | Viewed by 1528 | Submission Open
Keywords: trauma surgery; emergency surgery; DAMP; damage-associated molecular pattern; post-injury inflammation; hemorrhage; transplant surgery; robotic surgery; danger model; PRR; pattern recognition receptors
(This special issue belongs to the Section Medical Research)
Veterinary Pathology and Veterinary Anatomy: 2nd Edition submission deadline 31 Oct 2024 | Viewed by 496 | Submission Open
Keywords: veterinary pathology; veterinary anatomy; SARS-CoV2 pandemic; climate change; environmental pollution; diagnosis and treatment of animal diseases; computer modeling of pathological processes
(This special issue belongs to the Section Animal Science)
Bioinformatics Tools and Machine Learning Methods for Biomarker Discovery
edited by and
submission deadline 31 Oct 2024 | Viewed by 84 | Submission Open
Keywords: bioinformatics; machine learning; deep learning; biomarkers; multi-omics; NGS; single-cell; gene expression
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Nutritional Supplements and Cardiovascular Function in Athletes and Sedentary People submission deadline 31 Oct 2024 | Viewed by 79 | Submission Open
Keywords: athletes; sedentary; eating habits; nutrition; endothelium; microcirculation; nutritional supplements; oxidative stress; antioxidants; NRF2-signalling pathway; functional food; cardiovascular function; prevention
(This special issue belongs to the Section Medical Research)
Current and Future Perspectives of Artificial Intelligence in Medicine
edited by Giuseppe Consorti, Lisa Catarzi and
submission deadline 31 Oct 2024 | Viewed by 77 | Submission Open
Keywords: artificial intelligence; machine learning; deep learning; medical practices; artificial neural network; computational health informatics; predictive analytics in healthcare; ethics in AI for medical applications
(This special issue belongs to the Section Medical Research)
Role of Mitochondria in the Pathophysiology of Cardiovascular Diseases
edited by Yuriana Oropeza-Almazán and Héctor Chapoy-Villanueva
submission deadline 31 Oct 2024 | Viewed by 71 | Submission Open
Keywords: cardiovascular diseases (CVDs); mitochondria; mitochondrial dysfunction; ATP production; mitochondrial fission; mitochondrial fusion; electron transport chain; oxidative phosphorylation; mitophagy; cardiac hypertrophy; myocardial infarction; IR injury; mitochondrial ROS; ROS signaling; ion homeostasis; cardiac arrhythmias
(This special issue belongs to the Section Physiology and Pathology)
Mechanism, Diagnosis, and Treatment of Aortic Diseases: 2nd Edition
edited by
submission deadline 31 Oct 2024 | Viewed by 65 | Submission Open
Keywords: aorta; aortic disease; aortic aneurysm; aortic dissection; penetrating aortic ulcer; aortic stenosis; arteritis; pathomechanism; diagnosis; pharmacological therapy; invasive therapy; endovascular therapy; open surgery
(This special issue belongs to the Section Medical Research)
New Horizons of Adipose Tissue Disorders: From Hormonal Issues to Loose Connective Disease submission deadline 31 Oct 2024 | Viewed by 47 | Submission Open
Keywords: adipose tissue; lipedema; lymphedema; obesity; matrix; vascular and lymphatic disorder; connective tissue diseases; dysbiosis; inflammation; pain
(This special issue belongs to the Section Medical Research)
Advances and Applications of Neuroimaging in Brain Disorder
edited by Julio Plata-Bello
submission deadline 31 Oct 2024 | Viewed by 46 | Submission Open
Keywords: neuroimaging; magnetic resonance imaging; positron emission tomography; near infrared spectroscopy; brain; dementia; schizophrenia; depression; brain tumors; multiple sclerosis; autism
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Nanomedicine as a Path to Counteract Infectious Disease submission deadline 31 Oct 2024 | Viewed by 44 | Submission Open
Keywords: infectious diseases; nanomedicine; nanotechnology; nanoparticles; biomaterials; microbiota; biofilm treatment and/or eradication; antimicrobial activity; novel antimicrobial drugs
(This special issue belongs to the Section Medical Research)
Feature Papers in Periprosthetic Joint Infection
edited by Andrea Sambri and
submission deadline 31 Oct 2024 | Viewed by 40 | Submission Open
Keywords: orthoplastic approach; artificial intelligence; diagnosis and management of PJI; antibiotic therapy in prosthetic joint infections
(This special issue belongs to the Section Medical Research)
Human Infertility and Reproductive Endocrinology: 2nd Edition
edited by
submission deadline 31 Oct 2024 | Viewed by 40 | Submission Open
Keywords: infertility; reproduction; reproductive endocrinology; male infertility; female infertility
(This special issue belongs to the Section Reproductive and Developmental Biology)
Current Approaches and Future Directions in the Treatment of Gynecologic Tumors: Molecular Biology, Diagnostic Advancements and Targeted Therapeutic Strategies submission deadline 1 Nov 2024 | Viewed by 43 | Submission Open
Keywords: gynecologic tumors; cervical cancer; ovarian cancer; endometrial cancer; vulvar cancer; vaginal cancer; gestational trophoblastic disease; molecular mechanisms; diagnostic advancements; novel therapies
(This special issue belongs to the Section Physiology and Pathology)
Obstetrics and Gynecology Medicine: Go From Bench to Bedside submission deadline 8 Nov 2024 | 7 articles | Viewed by 7867 | Submission Open
Keywords: obstetrics; gynecology; translational research; translational medicine
(This special issue belongs to the Section Physiology and Pathology)
Obstructive Sleep Apnea: Current Knowledge and Future Perspectives submission deadline 21 Nov 2024 | 7 articles | Viewed by 13286 | Submission Open
Keywords: sleep apnoea syndrome— clinical and pathophysiological phenotypes; diagnosis and comorbidities; biomarkers; personalized treatment; predictors of outcomes; prognosis and mortality
(This special issue belongs to the Section Physiology and Pathology)
Current Challenges in Space Neuroscience submission deadline 21 Nov 2024 | 4 articles | Viewed by 6192 | Submission Open
Keywords: cognition; microgravity; sleep  ; stress; Martian and lunar dust; neural stem cells and progenitors
(This special issue belongs to the Section Astrobiology)
Hemophilia
edited by
submission deadline 22 Nov 2024 | Viewed by 220 | Submission Open
Keywords: hemophilia A-B; bleeding disorders; coagulation disorders; clotting factors; hemostasis; inherited bleeding disorders; hemorrhage; replacement therapy; gene therapy for hemophilia; hemophilia treatment centers; hemarthrosis; prophylactic treatment; joint bleeds; hemophilia genetics; hemophilia carriers
(This special issue belongs to the Section Medical Research)
Clinical Update for Resuscitation Science
edited by Mitsuaki Nishikimi
submission deadline 28 Nov 2024 | Viewed by 17 | Submission Open
Keywords: resuscitation science; cardiac arrest; acute respiratory failure; acute circulatory failure; trauma
(This special issue belongs to the Section Medical Research)
Cancer Epidemiology, Survival, and Disparities: Past, Present, and Future
edited by Adam Barsouk
submission deadline 28 Nov 2024 | Viewed by 6 | Submission Open
Keywords: epidemiology; survival; oncology; cancer; disparities
(This special issue belongs to the Section Epidemiology)
Untangling Host-Symbiont Coevolutionary History in the High Throughput Sequencing (HTS) Era
edited by and Andrew D. Sweet
submission deadline 29 Nov 2024 | 3 articles | Viewed by 5863 | Submission Open
Keywords: cophylogenetic methods; ectosymbionts; endosymbionts; epigenetics; introgression; long-read sequencing; genome architecture; genome evolution; hybridization; microbiomes; mutualist; parasite; phylogenomics; phylogeography; phylosymbiosis; population genomics; transcriptomics
(This special issue belongs to the Section Evolutionary Biology)
The Implication of Psychoactive Substance Consumption submission deadline 29 Nov 2024 | 2 articles | Viewed by 3025 | Submission Open
Keywords: psychoactive substances; recreational drugs; therapeutic potential; toxicity; analytical approaches; consumption
(This special issue belongs to the Section Pharmaceutical Science)
Structure, Dynamics and Energetics of Biomolecular Processes: Forces Driving Macromolecular Association, Folding, and Recognition
edited by and David P. Remeta
submission deadline 29 Nov 2024 | 1 articles | Viewed by 1342 | Submission Open
Keywords: molecular recognition and solvation; biomolecular structure and dynamics; ligand– receptor binding energetics; thermodynamic driving forces; macromolecular folding and stability; protein– nucleic acid interactions; intrinsically disordered proteins; liquid– liquid phase separation; protein aggregation and disease; drug discovery and optimization
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
The Effects of Neurosteroids on Neurological and Psychiatric Disorders
edited by Irina S. Balan
submission deadline 29 Nov 2024 | Viewed by 295 | Submission Open
Keywords: pregnane neurosteroids; androstane neurosteroids; sulfated neurosteroids; neuroactive steroids; neurological disorders; psychiatric disorders; therapeutic potential; neuroprotective properties; anti-inflammatory properties
(This special issue belongs to the Section Physiology and Pathology)
Cornea and Anterior Eye Diseases: 2nd Edition
edited by , and Giancarlo Montani
submission deadline 29 Nov 2024 | Viewed by 93 | Submission Open
Keywords: cornea; anterior eye; corneal dystrophy; dry eye; ocular surface; ocular imaging; contact lenses; myopia control with contact lenses; contact lens complications; primary eye care
(This special issue belongs to the Section Medical Research)
Pathogenesis, Pathological Features and Treatment of Sleep Disorders
edited by , Eunkee Bae and Wooyoung Im
submission deadline 29 Nov 2024 | Viewed by 68 | Submission Open
Keywords: insomnia; sleep apnea; parasomnia; cognitive behavioral therapy for insomnia; digital therapeutics
(This special issue belongs to the Section Physiology and Pathology)
Nutritional Supplementation, Body Composition and Performance in Athletes
edited by
submission deadline 29 Nov 2024 | Viewed by 33 | Submission Open
Keywords: optimal macro and micronutrients in exercise; plant-based food in sports nutrition; beetroot as ergogenic aid; body mass composition and nutrition practice; phase angle as VO2 max predictor; RED syndrome low and high energetic availability in sports praxis
(This special issue belongs to the Section Physiology and Pathology)
Trends in Microbiology 2024 submission deadline 30 Nov 2024 | 13 articles | Viewed by 16563 | Submission Open
Keywords: agricultural microbiology; clinical microbiology; environmental microbiology; food microbiology; industrial microbiology; marine microbiology; microbial biochemistry; microbial biofuel and bioenergy; microbial ecology; microbial evolution; microbial genetics; microbial metabolism; microbial pathogenesis; microbial physiology
(This special issue belongs to the Section Microbiology)
Evolutionary and Conservation Genetics: 3rd Edition
edited by and Ilenia Azzena
submission deadline 30 Nov 2024 | Viewed by 47 | Submission Open
Keywords: evolutionary genetics; population genetics; conservation genetics; phylogeography; phylogenetics; phylodynamics; molecular taxonomy
(This special issue belongs to the Section Evolutionary Biology)
Clinical Diagnosis and Treatment of Thrombocytopenia-Inducing Diseases
edited by
submission deadline 30 Nov 2024 | Viewed by 45 | Submission Open
Keywords: thrombocytopenia; antibody; malignancy; anemia; immune dysregulation; antibiotics; iatrogenic
(This special issue belongs to the Section Medical Research)
Animal Nutritional Physiology: Effects of Feed Additives on Livestock Products
edited by and Katarzyna Poltowicz
submission deadline 30 Nov 2024 | Viewed by 43 | Submission Open
Keywords: feed additives; animal health; animal performance; animal-derived products; animal nutritional physiology
(This special issue belongs to the Section Physiology and Pathology)
Advances in Clinical Microbiology Detection
edited by Rossana Scutari
submission deadline 30 Nov 2024 | Viewed by 18 | Submission Open
Keywords: clinical microbiology; microbiology techniques; novel identification technologies; rapid diagnostics; novel screening and diagnostic methods; next-generation sequencing; metagenomics; microorganism detection and analysis; microbial monitoring
Hansen's Disease—Epidemiology, Diagnosis, Treatment and Complications
edited by Karen Olshtain-Pops
submission deadline 30 Nov 2024 | Viewed by 12 | Submission Open
Keywords: hansen's disease; leprosy; Mycobacterium leprae
(This special issue belongs to the Section Epidemiology)
What Is New in Psychiatry and Psychopharmacology—2nd Edition submission deadline 30 Nov 2024 | Viewed by 10 | Submission Open
Keywords: clinical psychiatry; biomarkers; psychopharmacology; addictions; agitations; pharmacological resistance; transcranial magnetic resonance
(This special issue belongs to the Section Pharmaceutical Science)
Advances in Knee Biomechanics
edited by Jason Shearn
submission deadline 2 Dec 2024 | 2 articles | Viewed by 1373 | Submission Open
Keywords: knee; tendon; ligament; injury; repair; healing; biomechanics; advanced techniques
(This special issue belongs to the Section Physiology and Pathology)
Advances in Pulmonary Fibrosis
edited by Mary M. Salvatore and Maria Padilla
submission deadline 2 Dec 2024 | Viewed by 30 | Submission Open
Keywords: lung fibrosis; biomarkers; artificial intelligence; lung cancer in pulmonary fibrosis
(This special issue belongs to the Section Medical Research)
Structure, Activity, and Function of Protein Methyltransferases Volume 2 submission deadline 13 Dec 2024 | Viewed by 187 | Submission Open
(This special issue belongs to the Section Proteins and Proteomics)
Feature Papers in Origins of Life 2024
edited by James R. Lyons
submission deadline 13 Dec 2024 | Viewed by 64 | Submission Open
Keywords: astrobiology; astrochemistry; planetary science; geobiology; prebiotic chemistry; chirality; chemical evolution; protocells; synthetic biology; complex systems
(This special issue belongs to the Section Origin of Life)
State of the Art Diagnosis and Treatment into Cerebral Veins and Dural Sinuses Thrombosis
edited by , and
submission deadline 15 Dec 2024 | Viewed by 16 | Submission Open
Keywords: cerebral vein and intracranial dural sinus thrombosis (CVT); thrombophilia; isolated intracranial hypertension; non-enhanced computer tomography (NECT) of the head; computer tomography venography (CTV); magnetic resonance imaging (MRI) of the head; magnetic resonance venography (MRV); anticoagulation
(This special issue belongs to the Section Physiology and Pathology)
Cell Biology and Molecular Diagnosis of Pancreatic Cancer
edited by
submission deadline 16 Dec 2024 | Viewed by 40 | Submission Open
Keywords: pancreatic ductal adenocarcinoma; pancreatic neuroendocrine tumors; pancreatic intraepithelial neoplasia; intraductal papillary mucinous neoplasms; pancreatic cancer stem cells; pancreatic microenvironment; liquid biopsy; cystic fluid; saliva; genomics/proteomics/lipidomics; transcription and translation; cytokines; inflammation; metastasis
(This special issue belongs to the Section Physiology and Pathology)
Novel Approaches in Plastic and Reconstructive Surgery to Improve Quality of Life
edited by Silvan Maximilian Klein and Alexandra M. Anker
submission deadline 17 Dec 2024 | 3 articles | Viewed by 2699 | Submission Open
Keywords: reconstructive surgery; peripheral nerve injury; tissue repair; tissue engineering; peripheral nerve gaps; management of bone defects; molecular aspects of tissue repair; cancer therapy; cancer diagnostics; tissue imaging; artificial intelligence; cell-based tissue repair; rehabilitation after reconstructive surgery; facial reconstruction; breast reconstruction; lymphedema surgery
(This special issue belongs to the Section Medical Research)
The Development and Evolution of Legumes
edited by Shaoli Zhou
submission deadline 17 Dec 2024 | Viewed by 215 | Submission Open
Keywords: legumes; development; evolution; genetics; breeding; taxonomy
(This special issue belongs to the Section Plant Science)
COVID-19 and SARS-CoV-2 Investigations: Characteristics, Clinical Course, Prevention, Treatment and Prognosis submission deadline 20 Dec 2024 | 8 articles | Viewed by 11060 | Submission Open
Keywords: COVID-19; SARS-CoV-2; public health; biological risk; infectious diseases; vaccines and vaccinations; clinical recognition; treatment; disease course; prognosis
(This special issue belongs to the Section Epidemiology)
Plants as a Promising Biofactory for Bioactive Compounds: 2nd Edition
edited by
submission deadline 30 Dec 2024 | 2 articles | Viewed by 2297 | Submission Open
Keywords: plant cell culture; plant tissue culture; medicinal plants; secondary metabolites; bioactive compounds; nutraceuticals; recombinant proteins; biologics
(This special issue belongs to the Section Plant Science)
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