Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Global Developments in Musculoskeletal Health Research and Practice
edited by Stefanie Krauth, and John A. Hammond
submission deadline 31 May 2025 | Viewed by 91 | Submission Open
Keywords: musculoskeletal diseases; therapeutics; epidemiological studies
(This special issue belongs to the Section Epidemiology)
Pediatric Ophthalmic Pathology—Integrating Clinical and Basic Research
edited by and Brenda L. Bohnsack
submission deadline 31 May 2025 | Viewed by 83 | Submission Open
Keywords: congenital eye anomalies; anterior segment disorders; genetic eye disorders; pediatric eye conditions; pediatric ophthalmology
(This special issue belongs to the Section Physiology and Pathology)
Therapeutic Approaches of Marine Natural Products in Health and Disease
edited by Thilina U. Jayawardena and D. P. Nagahawatta
submission deadline 31 May 2025 | Viewed by 73 | Submission Open
Keywords: marine natural products; bioactive compounds; drug discovery; therapeutic applications
(This special issue belongs to the Section Pharmaceutical Science)
Gut Microbes Associating with the Host
edited by and
submission deadline 10 Jun 2025 | Viewed by 491 | Submission Open
Keywords: gut microbes; microbiome; animals; nutrition
(This special issue belongs to the Section Microbiology)
Antibiotic Resistance in Biofilm: 2nd Edition
edited by
submission deadline 16 Jun 2025 | 4 articles | Viewed by 4367 | Submission Open
Keywords: biofilm; food industry; antimicrobial resistance; antibiotic resistance gene transfer; antibiofilm activity; control strategies
(This special issue belongs to the Section Microbiology)
Advances in the Treatment of Pulmonary Hypertension and Pulmonary Embolism submission deadline 16 Jun 2025 | 1 articles | Viewed by 768 | Submission Open
Keywords: pulmonary hypertension; pulmonary embolism; therapy; cardiac imaging; artificial intelligence
(This special issue belongs to the Section Medical Research)
New Restorative Technologies in the Management and Characterization Techniques of the Hard and Soft Tissues of Oral Cavity
edited by Ilaria Giovannacci, Silvia Pizzi and Careri Maria
submission deadline 20 Jun 2025 | Viewed by 72 | Submission Open
Keywords: microscopy analysis imaging; jaw bone; oral mucosa; autofluorescence; adhesive dentistry; oral surgery; regenerative medicine; lasers
(This special issue belongs to the Section Medical Research)
Nutrition, Exercise and Stress
edited by Maleah Holland-Winkler
submission deadline 25 Jun 2025 | Viewed by 79 | Submission Open
Keywords: nutrition; exercise; stress
(This special issue belongs to the Section Physiology and Pathology)
Microvascular Dynamics: Insights and Applications
edited by and Friedrich Jung
submission deadline 26 Jun 2025 | 4 articles | Viewed by 8716 | Submission Open
Keywords: microvessels; dynamics; velocity; flow; rheology; in vitro; animals; humans; biomarkers; imaging; simulations; models; preclinical; clinical
(This special issue belongs to the Section Physiology and Pathology)
Advances in Research on Motor Deficits Caused by Neurological Disorders: From Mechanism to Treatment
edited by
submission deadline 26 Jun 2025 | Viewed by 332 | Submission Open
Keywords: neurological disorders; neurodegenerative diseases; brain injury; spinal cord injury; stroke; cerebral palsy; peripheral nerve injury; paralysis; spasticity; contracture; muscle weakness; postural asymmetry; gate pattern changes; uncontrolled movements
(This special issue belongs to the Section Medical Research)
Innovative Strategies in Insecticide Resistance and Sustainable Pest Management
edited by Chengwang Sheng, and
submission deadline 27 Jun 2025 | 1 articles | Viewed by 942 | Submission Open
Keywords: insecticide resistance; sustainable pest management; integrated pest management; bioinsecticides; physical pest control; gene editing; insect sterilization; transgenic technology; molecular targets for pesticides
(This special issue belongs to the Section Animal Science)
From Stem Cells to Embryos, Congenital Anomalies and Epidemiology
edited by , Soultana Meditskou and
submission deadline 30 Jun 2025 | 6 articles | Viewed by 12223 | Submission Open
Keywords: stem cell research; human embryonic development; birth defects epidemiology; birth defects prevalence; maternal and fetal medicine; congenital anomalies prevention; ultrasound evaluation; pre-birth assessment; prenatal screening; healthcare
(This special issue belongs to the Section Epidemiology)
Retinal Diseases: From Molecular Mechanisms to Therapeutics
edited by
submission deadline 30 Jun 2025 | 6 articles | Viewed by 10932 | Submission Open
Keywords: retinal disease; inflammatory disease; genetic diseases; ocular drug development
(This special issue belongs to the Section Physiology and Pathology)
New Horizons of Adipose Tissue Disorders: From Hormonal Issues to Loose Connective Disease submission deadline 30 Jun 2025 | 3 articles | Viewed by 10072 | Submission Open
Keywords: adipose tissue; lipedema; lymphedema; obesity; matrix; vascular and lymphatic disorder; connective tissue diseases; dysbiosis; inflammation; pain
(This special issue belongs to the Section Physiology and Pathology)
New Insights into Allergic Eye Diseases submission deadline 30 Jun 2025 | 2 articles | Viewed by 8932 | Submission Open
Keywords: allergy; IgE; IL-4; IL-5; IL-13; TNF-alpha; mast cells; eosinophils; Th1 cells; Th2 cells; therapeutics; immunopathogenesis; immunopathology; conjunctivitis; keratoconjunctivitis
(This special issue belongs to the Section Medical Research)
Advances in Endoscopic, Surgical, and Interventional Radiological Management of Gastrointestinal Diseases
edited by
submission deadline 30 Jun 2025 | 3 articles | Viewed by 3242 | Submission Open
Keywords: gastrointestinal disease; endoscopic cystogastrostomy; endoscopic biliary prosthesis; endoscopic pancreatic prosthesis; endoscopic necrosectomy; esophagectomy; gastrectomy; bowel resection; colectomy; pancreatectomy; hepatectomy; liver transplantation; gastroenterology; surgery; interventional radiology
(This special issue belongs to the Section Medical Research)
Nutritional Supplements and Cardiovascular Function in Athletes and Sedentary People submission deadline 30 Jun 2025 | 2 articles | Viewed by 3211 | Submission Open
Keywords: athletes; sedentary; eating habits; nutrition; endothelium; microcirculation; vascular function; nutritional supplements; oxidative stress; antioxidants; NRF2-signaling pathway; functional food; cardiovascular function; prevention; physical activity
(This special issue belongs to the Section Medical Research)
Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders
edited by , , Maria Chiara Vulpiani, Maria Cristina D'Agostino, Larisa Ryskalin and Federica Fulceri
submission deadline 30 Jun 2025 | 2 articles | Viewed by 2882 | Submission Open
Keywords: shockwave; tissue regeneration; pain; functional recovery and healing; physical medicine and rehabilitation; clinical applications; imaging
(This special issue belongs to the Section Medical Research)
Musculoskeletal Pain and Disorders: Diagnosis, Treatment and Management submission deadline 30 Jun 2025 | 1 articles | Viewed by 1406 | Submission Open
Keywords: pain; connective tissue; musculoskeletal disorders; fascia; muscles; tendons; ligaments
(This special issue belongs to the Section Physiology and Pathology)
Current Advances in Lung Cancer Diagnosis and Treatment
edited by , Daesik Yang and
submission deadline 30 Jun 2025 | 2 articles | Viewed by 1248 | Submission Open
Keywords: lung cancer; underlying lung disease; radiotherapy; systemic therapy; survival outcomes; complication; biomarkers
(This special issue belongs to the Section Medical Research)
Eye Diseases: Diagnosis and Treatment, 3rd Edition
edited by and Laura De Diego-García
submission deadline 30 Jun 2025 | 2 articles | Viewed by 1127 | Submission Open
Keywords: ocular treatment; ocular diseases; retina; anterior eye; posterior eye; ocular biomarkers
(This special issue belongs to the Section Medical Research)
Innovative Applications of Extracellular Vesicles: From Diagnostics to Drug Delivery
edited by Alessandra Lo Cicero
submission deadline 30 Jun 2025 | 1 articles | Viewed by 1042 | Submission Open
Keywords: extracellular vesicles; exosomes; cancer; cardiovascular diseases; neurodegenerative diseases; biomarkers; diagnostics; cell-cell communication; drug delivery; therapeutics
(This special issue belongs to the Section Physiology and Pathology)
Advancements in Veterinary Oncology submission deadline 30 Jun 2025 | Viewed by 1040 | Submission Open
Keywords: veterinary and comparative oncology; epidemiology; tumor biology; diagnosis; treatment; biomarkers
(This special issue belongs to the Section Animal Science)
Neuroinflammation in Huntington’s Disease: Detrimental Crosstalk submission deadline 30 Jun 2025 | 1 articles | Viewed by 985 | Submission Open
Keywords: Huntington’ s disease; mutant huntingtin (mHtt) protein; central nervous system; mutated protein; glial cells
(This special issue belongs to the Section Physiology and Pathology)
Advanced Heart Failure and Transplant Cardiology
edited by David Dobarro
submission deadline 30 Jun 2025 | 1 articles | Viewed by 830 | Submission Open
Keywords: heart failure; heart transplantation; cardiology; ventricular assist devices
(This special issue belongs to the Section Medical Research)
Physiological Responses of Plants Under Abiotic Stresses
edited by Dawei Shi
submission deadline 30 Jun 2025 | 1 articles | Viewed by 777 | Submission Open
Keywords: crops; woody plants; horticultural plants; physiological responses; abiotic stresses; photosynthesis
(This special issue belongs to the Section Plant Science)
Feature Paper in Genetics and Genomics submission deadline 30 Jun 2025 | 1 articles | Viewed by 693 | Submission Open
Keywords: DNA; RNA; gene discovery and function; gene expression; population genetics; genome projects; comparative and functional genomics; medical genetics; complex traits; chromosome biology; epigenomics and epigenetics; statistical genetics and methodology; genomic assay technology; sequencing technologies; bioinformatics
(This special issue belongs to the Section Genetics and Genomics)
Genetics, Breeding and Reproduction of Honeybees: Second Edition
edited by
submission deadline 30 Jun 2025 | 1 articles | Viewed by 556 | Submission Open
Keywords: phenomics; genetics; genomics; functional genomics; metabolomics; functional genes identification; genetics editing; genome selection; genetic evaluation; hybrid breeding; egg-laying; honey production; queen breeding; varroa resistance
(This special issue belongs to the Section Animal Science)
Mechanism, Diagnostic and Therapeutic Novelties in Dermatology: 3rd Edition
edited by Jose Carlos Armario Hita, and
submission deadline 30 Jun 2025 | 1 articles | Viewed by 468 | Submission Open
Keywords: physiopathology; skin sonography; dermoscopy; innovation; confocal microscopy; biological treatment; psoriasis; atopic dermatitis; inmmunomediated diseases; urticaria; laser CO2
(This special issue belongs to the Section Medical Research)
Mechanism, Diagnosis, and Treatment of Aortic Diseases: 2nd Edition
edited by
submission deadline 30 Jun 2025 | Viewed by 412 | Submission Open
Keywords: aorta; aortic disease; aortic aneurysm; aortic dissection; penetrating aortic ulcer; aortic stenosis; arteritis; pathomechanism; diagnosis; pharmacological therapy; invasive therapy; endovascular therapy; open surgery
(This special issue belongs to the Section Medical Research)
Advances and Applications of Neuroimaging in Brain Disorder
edited by Julio Plata-Bello
submission deadline 30 Jun 2025 | Viewed by 221 | Submission Open
Keywords: neuroimaging; magnetic resonance imaging; positron emission tomography; near infrared spectroscopy; brain; dementia; schizophrenia; depression; brain tumors; multiple sclerosis; autism
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
From Pathophysiology to Pathology—An Update on Diabetic Kidney Disease
edited by Sharma Prabhakar
submission deadline 30 Jun 2025 | Viewed by 190 | Submission Open
Keywords: diabetic kidney disease; epithelial– mesenchymal transition; renin– angiotensin– aldosterone system; sodium glucose transporter 2; albuminuria
(This special issue belongs to the Section Physiology and Pathology)
Advanced Neuroimaging Techniques in Stroke Management
edited by Foteini Christidi, and Efstratios Karavasilis
submission deadline 30 Jun 2025 | Viewed by 172 | Submission Open
Keywords: stroke; neuroimaging; MRI; CT; stroke management; biomarkers; acute stroke; chronic stroke; neuroplasticity; neuromodulation
(This special issue belongs to the Section Medical Research)
Chronic Obstructive Pulmonary Disease: Clinical, Epidemiological, and Molecular Bases
edited by Josef Yayan
submission deadline 30 Jun 2025 | Viewed by 170 | Submission Open
Keywords: chronic obstructive pulmonary disease; COPD; emphysema; chronic bronchitis
(This special issue belongs to the Section Medical Research)
Innovative Technologies in Pain Management submission deadline 30 Jun 2025 | Viewed by 154 | Submission Open
Keywords: pain management; extended reality (XR) technologies; gamification for pain relief; psychosocial variables; interdisciplinary approaches
(This special issue belongs to the Section Physiology and Pathology)
Biological Insights into Drug Safety for Vulnerable Populations submission deadline 30 Jun 2025 | Viewed by 144 | Submission Open
Keywords: drug safety; vulnerable populations; pharmacotherapy; drug metabolism and efficacy; pediatric medication safety; drug pharmacokinetics and pharmacodynamics
(This special issue belongs to the Section Pharmaceutical Science)
Recent Advances in Non-Invasive Diagnosis Based on Volatile Metabolites
edited by Kiran Sankar Maiti
submission deadline 30 Jun 2025 | Viewed by 143 | Submission Open
Keywords: volatile metabolites; breath analysis; headspace analysis; biofluids; non-invasive; diagnosis
(This special issue belongs to the Section Medical Research)
Acute Kidney Events in Intensive Care
edited by
submission deadline 30 Jun 2025 | Viewed by 114 | Submission Open
Keywords: acute kidney events; ICU; critically ill; RRT; outcome; acute kidney disease; chronic kidney disease; biomarkers
(This special issue belongs to the Section Medical Research)
Advancements in Hematologic Malignancies: Innovations in Diagnosis and Therapy
edited by Chohao Lee
submission deadline 30 Jun 2025 | Viewed by 107 | Submission Open
Keywords: hematologic malignancies; stem cell transplantation; CAR-T cell therapy; immunotherapy; multiple myeloma; leukemia; precision medicine; hematopoietic stem cells; drug resistance; novel therapeutics
(This special issue belongs to the Section Medical Research)
Integrating Bioinformatics and Artificial Intelligence: Transforming Data into Insights for Precision Medicine
edited by Usef Faghihi
submission deadline 30 Jun 2025 | Viewed by 102 | Submission Open
Keywords: bioinformatics; artificial intelligence; precision medicine; machine learning; computational biology; multi-omics data integration; biomarker discovery; predictive modeling; personalized medicine; computational drug discovery
(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)
The Other Pediatric Primary Headaches: 2nd Edition
edited by , and Giuseppe Santangelo
submission deadline 30 Jun 2025 | Viewed by 100 | Submission Open
Keywords: pediatric TACs; primary pediatric headaches; pediatric tension headaches; preventive treatment; acute treatment; clinical features; children; pediatric headaches in IV 3ICHD
(This special issue belongs to the Section Medical Research)
Recent Advances in Valve Therapy: Clinical and Molecular Perspectives
edited by Panayotis Vlachakis, Konstantinos Toutouzas and Constantina Aggeli
submission deadline 30 Jun 2025 | Viewed by 98 | Submission Open
Keywords: transcatheter aortic valve implantation (TAVI); valve-in-valve; long-term outcomes; aortic stenosis; molecular mechanisms in valve disease; structural heart disease
(This special issue belongs to the Section Medical Research)
Advances in CT Angiography and Perfusion
edited by Marcin Sawicki
submission deadline 30 Jun 2025 | Viewed by 91 | Submission Open
Keywords: CT angiography; CT perfusion; artificial intelligence; dynamic CT angiography; 4D CT angiography; acute ischemic stroke
(This special issue belongs to the Section Radiobiology and Nuclear Medicine)
Veterinary Pathology and Veterinary Anatomy: 3rd Edition submission deadline 30 Jun 2025 | Viewed by 85 | Submission Open
Keywords: veterinary pathology; veterinary anatomy; SARS-CoV-2 pandemic; climate change; environmental pollution; diagnosis and treatment of animal diseases; computer modelling of pathological processes
(This special issue belongs to the Section Animal Science)
Role of the Kynurenine System in Neurological Disorders
edited by and Tamás Körtési
submission deadline 30 Jun 2025 | Viewed by 72 | Submission Open
Keywords: kynurenine pathway; neurological disorders; kynurenic acid; quinolinic acid
(This special issue belongs to the Section Physiology and Pathology)
Advances in Veterinary Ophthalmology: Innovative Approaches to Ocular Diseases in Animals
edited by
submission deadline 30 Jun 2025 | Viewed by 67 | Submission Open
Keywords: ocular diseases; dogs; cats; tear film; molecular mechanism
(This special issue belongs to the Section Animal Science)
Prevention, Evaluation, and Control of HIV Infection
edited by Οlga Tsachouridou
submission deadline 30 Jun 2025 | Viewed by 62 | Submission Open
Keywords: HIV/AIDS; HIV testing; immune activation; HIV pathogenesis; inflammation; HIV transmission and prevention; antiretroviral therapy
(This special issue belongs to the Section Microbiology)
Innovations in Pediatric Immunology and Environmental Health
edited by
submission deadline 30 Jun 2025 | Viewed by 53 | Submission Open
Keywords: indoor microbiome; children's health; environmental microorganisms; maternal factors; allergies and asthma; immune development
(This special issue belongs to the Section Physiology and Pathology)
Infection, Inflammation and Rheumatology
edited by
submission deadline 4 Jul 2025 | 1 articles | Viewed by 1262 | Submission Open
Keywords: infection; COVID-19; inflammation; vaccination; rheumatic diseases
(This special issue belongs to the Section Physiology and Pathology)
Update on Microalgae Metabolites submission deadline 10 Jul 2025 | Viewed by 95 | Submission Open
Keywords: biosynthesis; culture conditions; bioactive compounds; biological activity; biorefinery; proteins; peptides; antifreeze proteins; enzymes; carbohydrates; exocellular polysaccharides; carbohydrate-binding proteins; lipids; fatty acids; chlorophylls; carotenoids; phycobiliproteins; vitamins; minerals; trace elements; sterols; secondary metabolites; downstream processing; purification; safety; regulatory issues; clinical tests
(This special issue belongs to the Section Microbiology)
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