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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Genetics, Breeding and Reproduction of Honeybees: Second Edition

edited by

Xiao Chen

submission deadline 30 Sep 2026 | 2 articles | Viewed by 7056 | Submission Open

Keywords: phenomics; genetics; genomics; functional genomics; metabolomics; functional genes identification; genetics editing; genome selection; genetic evaluation; hybrid breeding; egg-laying; honey production; queen breeding; varroa resistance

(This special issue belongs to the Section Animal Science)

Natural Products and Modern Drug Discovery: Emerging Strategies Targeting Cancer- and Disease-Related Molecular Mechanisms

edited by

Chia-Jui Weng

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4859 | Submission Open

Keywords: natural products; phytochemicals; drug discovery; bioactivity profiling; pharmacophore modeling; synthetic biology; cancer therapy; microbial metabolites

(This special issue belongs to the Section Medical Research)

Advances in the Rehabilitation of Stroke

edited by

Chia Huei Lin

submission deadline 30 Sep 2026 | 1 articles | Viewed by 4374 | Submission Open

Keywords: stroke; acute stroke; chronic stroke; post-acute stroke; functional recovery; rehabilitation

(This special issue belongs to the Section Medical Research)

Advances in Plant Biotechnology and Molecular Breeding

edited by Serik Eliby, Nikolai Borisjuk and

Yuri Shavrukov

submission deadline 30 Sep 2026 | 3 articles | Viewed by 4353 | Submission Open

Keywords: doubled haploidy; genetic engineering; genome editing; genomics; marker-assisted selection; molecular breeding; molecular markers; plant biotechnology

(This special issue belongs to the Section Plant Science)

Advances in Personalized Management in Orthopedics and Traumatology

edited by

Tudor Sorin Pop

and

Andrei Marian Feier

submission deadline 30 Sep 2026 | 4 articles | Viewed by 3594 | Submission Open

Keywords: personalized orthopedics; hip replacement; knee replacement; patient-specific treatment; clinical outcomes

(This special issue belongs to the Section Medical Research)

Prebiotic Chemistry: The Molecular Origins of Life

edited by

Nigel Mason

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2855 | Submission Open

Keywords: astrobiology; astrochemistry; biochemistry; computational modelling; geochemistry; metabolic pathways; lipid formation; peptide synthesis; photochemistry; radiation chemistry; RNA world; self-assembly; systems chemistry

(This special issue belongs to the Section Origins of Life)

Research Updates in Hematology

edited by

Eleni Gavriilaki

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2761 | Submission Open

Keywords: antiphospholipid syndrome; complement; endothelium; hemoglobinopathies; hemophilia; leukemias; lymphomas; multiple myeloma; pediatric hematology; thrombosis

(This special issue belongs to the Section Physiology and Pathology)

Nutrition–Physiology Interactions in Aquatic Species

edited by

Dizhi Xie

Songlin Li

and

Kangle Lu

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2675 | Submission Open

Keywords: aquatic animal nutrition; fish physiology; sustainable aquaculture; alternative lipid sources; alternative protein sources; gut– microbiota interactions

(This special issue belongs to the Section Animal Science)

Advances in Imaging for Female Patients: Breast and Gynecological Diagnostics

edited by Silvia Gigli, Emanuele David and Giacomo Bonito

submission deadline 30 Sep 2026 | 2 articles | Viewed by 2029 | Submission Open

Keywords: breast cancer; breast screening; gynecological cancer; mammography; CEM; ultrasound; MRI; PET/TC; radiomics; artificial intelligence

(This special issue belongs to the Section Medical Research)

Ocular Diseases: Mechanisms, Diagnostics, and Emerging Therapeutic Strategies

edited by Joanna Dolar-Szczasny

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1978 | Submission Open

Keywords: molecular mechanisms of eye disease; oxidative stress and inflammation; neurodegeneration in vision; ocular biomarkers; pharmacological therapies; gene therapy; stem cell and regenerative approaches; precision/personalized ophthalmology

(This special issue belongs to the Section Medical Research)

Pathophysiology, Diagnosis, and Treatments of Intestinal Diseases—2nd Edition

edited by Amosy Ephreim M’Koma

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1915 | Submission Open

Keywords: gastrointestinal disease/disorders; pathophysiology; diagnostics and treatment

(This special issue belongs to the Section Physiology and Pathology)

Advanced Research in Plant–Pathogen Interactions

edited by

Tianye Zhang

and

Bin Yong

submission deadline 30 Sep 2026 | 3 articles | Viewed by 1844 | Submission Open

Keywords: plant-pathogen interaction; plant immunity; pathogen effectors; host defense mechanisms; autophagy; noncoding RNA; small peptides; molecular plant pathology; crop disease resistance

(This special issue belongs to the Section Plant Science)

Microvascular Research: Advances and Perspectives

edited by

Panagiota Anyfanti

and

Theodoros Dimitroulas

submission deadline 30 Sep 2026 | 2 articles | Viewed by 1627 | Submission Open

Keywords: microvasculature; microvascular dysfunction; systemic diseases; pathophysiology; cardiovascular diseases; hypertension; therapeutic advances

(This special issue belongs to the Section Medical Research)

Microbial Biotechnology and Biomanufacturing

edited by

Sheng Tong

Dexin Wang

and

Guirong Tang

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1563 | Submission Open

Keywords: synthetic biology tools; microbial biomanufacturing; future foods; bulk chemicals; plant natural products

(This special issue belongs to the Section Synthetic Biology and Systems Biology)

The Biological Impacts of Fetal Alcohol Exposure

edited by Kelly J. Huffman

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1345 | Submission Open

Keywords: fetal alcohol spectrum disorders; fetal alcohol syndrome; brain development; behavioral development; prenatal exposure

(This special issue belongs to the Section Reproductive and Developmental Biology)

Neurorehabilitation: Technology-Driven Recovery and Functional Rewiring

edited by

Simone Carozzo

submission deadline 30 Sep 2026 | 1 articles | Viewed by 1101 | Submission Open

Keywords: cognitive-motor recovery; neuroplasticity; multidimensional assessment; post-stroke rehabilitation

(This special issue belongs to the Section Medical Research)

Molecular Underpinnings of Cancer: Pathways to Targeted Therapy

edited by

Rahul Shivahare

and

Joon-Yong Chung

submission deadline 30 Sep 2026 | 1 articles | Viewed by 990 | Submission Open

Keywords: signaling pathways; tumor microenvironment; cancer metabolism; biomarkers; drug resistance; precision medicine; targeted therapy

(This special issue belongs to the Section Medical Research)

Biomaterials for Antimicrobial Applications

edited by

Moorthy Maruthapandi

submission deadline 30 Sep 2026 | 1 articles | Viewed by 977 | Submission Open

Keywords: antimicrobial biomaterials; translational materials; antifouling and antibiofilm surfaces; antimicrobial coatings; controlled release; diagnostic materials; implant surfaces; infection-resistant implants; wound healing and tissue engineering

(This special issue belongs to the Section Microbiology)

Biochemical Modulators in Chronic Diseases: The Antioxidant/Anti-Inflammatory Interdependence—2nd Edition

edited by

Emma Borrelli

submission deadline 30 Sep 2026 | 1 articles | Viewed by 926 | Submission Open

Keywords: oxidative stress; inflammation; redox modulator; anti-inflammatory agents; chronic diseases; antioxidant paradox; reactive oxygen species

(This special issue belongs to the Section Pharmaceutical Science)

Agroforestry Systems and Global Change: Carbon and Nitrogen Cycling Regulation, Ecosystem Functions, and Sustainable Development

edited by

Ling Zhang

, Xintong Xu and Xi Yuan

submission deadline 30 Sep 2026 | 1 articles | Viewed by 846 | Submission Open

Keywords: carbon and nitrogen cycling; plant– microbe– soil interactions; plant-ecology

(This special issue belongs to the Section Biodiversity, Ecology and Evolution)

The Oral-Systemic Link in Chronic Mucosal Diseases

edited by

Ioanina Parlatescu

submission deadline 30 Sep 2026 | 1 articles | Viewed by 845 | Submission Open

Keywords: oral diseases; general diseases; biomarkers

(This special issue belongs to the Section Medical Research)

Parasite Detection, Control Strategies and Risk Factors Related to Reproductive Health in Livestock

edited by

Ioannis Tsakmakidis

and

Ioannis A. Giantsis

submission deadline 30 Sep 2026 | Viewed by 761 | Submission Open

Keywords: livestock; parasite control; reproductive health; management

(This special issue belongs to the Section Animal Science)

Women's Health and Well-Being: A Focus on Obstetrics and Gynecologic Medicine

edited by Luca Roncati

submission deadline 30 Sep 2026 | 1 articles | Viewed by 732 | Submission Open

Keywords: women’ s health; gynecology; gynecopathology; preventive gynecological oncology; senology; breast cancer; cervical cancer; sexually transmitted infections; human papillomavirus; autoimmune diseases

(This special issue belongs to the Section Medical Research)

Latest Research Updates on Laparoscopy

edited by Niculae N. Iordache and Claudiu-Octavian Ungureanu

submission deadline 30 Sep 2026 | 1 articles | Viewed by 667 | Submission Open

Keywords: laparoscopy; minimally invasive surgery; surgical innovation; imaging and navigation; artificial intelligence in surgery; surgical outcomes; clinical advancements

(This special issue belongs to the Section Medical Research)

Pathology, Diagnosis, and Treatment of Cardiomyopathies

edited by

Sanjay Sivalokanathan

submission deadline 30 Sep 2026 | 1 articles | Viewed by 438 | Submission Open

Keywords: cardiomyopathies; pathogenetic mechanisms; diagnoses

(This special issue belongs to the Section Medical Research)

Wearable Biosensor Methodologies for Disease Diagnosis and Health Monitoring

edited by

Amin Hekmatmanesh

submission deadline 30 Sep 2026 | Viewed by 337 | Submission Open

Keywords: brain– computer interface (BCI); electroencephalogram (EEG); machine learning; biomedical signal processing; brain computer interface; health monitoring

(This special issue belongs to the Section Medical Research)

Cognitive and Imaging Mechanisms in Neurological Disorders

edited by Foteini Christidi,

Anna Tsiakiri

and

Efstratios Karavasilis

submission deadline 30 Sep 2026 | Viewed by 281 | Submission Open

Keywords: neurological disorders; cognitive dysfunction; neuropsychological assessment; neuroimaging; structural MRI; functional MRI; multimodal neuroimaing; biomarkers; machine learning in neurology; neurorehabilitation

(This special issue belongs to the Section Medical Research)

Genetic Regulation of Natural Product Biosynthesis in Medicinal Plants

edited by

Peng Di

and Lin Cheng

submission deadline 30 Sep 2026 | Viewed by 280 | Submission Open

Keywords: medicinal plants; natural products; biosynthesis; genetic regulation; transcription factors; multi-omics; metabolic engineering; specialized metabolism

(This special issue belongs to the Section Plant Science)

Gender Medicine in Dermatology, Rheumatology and Immunology

edited by

Marzia Caproni

submission deadline 30 Sep 2026 | Viewed by 239 | Submission Open

Keywords: gender medicine; sex and gender differences; immune-mediated diseases; autoimmunity and inflammation; dermatology; rheumatology; immunology

(This special issue belongs to the Section Medical Research)

Biomarkers in Ischemic Stroke: From Discovery to Clinical Applications

edited by Hock-Kean Liew

submission deadline 30 Sep 2026 | Viewed by 229 | Submission Open

Keywords: ischemic stroke; biomarkers; neuroinflammation; oxidative stress; excitotoxicity; thrombolysis; mechanical thrombectomy; blood– brain barrier; neuroprotection; precision medicine

(This special issue belongs to the Section Medical Research)

Advanced Optical Imaging for Tissue and Tumour Characterization

edited by

Ana Batista

and Ana Teresa A. Amaral

submission deadline 30 Sep 2026 | Viewed by 222 | Submission Open

Keywords: optical imaging; label-free imaging; functional imaging; multimodal imaging; tissue characterization; tumour microenvironment; tumour heterogeneity; extracellular matrix; therapeutic monitoring

(This special issue belongs to the Section Medical Research)

New Insights into Skin Health and Disease

edited by

Jeng-Wei Tjiu

and Mark G. Lebwohl

submission deadline 30 Sep 2026 | Viewed by 219 | Submission Open

Keywords: skin health; inflammatory skin diseases; immune regulation; autoimmune skin disorders; skin cancer; targeted therapies; translational dermatology; long-term disease management

(This special issue belongs to the Section Medical Research)

Synthetic Biology and Biotechnology Application of Algae

edited by Fantao Kong and

Chaogang Wang

submission deadline 30 Sep 2026 | Viewed by 195 | Submission Open

Keywords: synthetic biology; algal biotechnology; metabolic engineering; biofuels; carbon capture; high-value products; genetic tools; bioremediation

(This special issue belongs to the Section Synthetic Biology and Systems Biology)

New Challenges in Fracture Management

edited by

Kai-Cheng Lin

submission deadline 30 Sep 2026 | Viewed by 182 | Submission Open

Keywords: fracture; extremity trauma; orthopedic trauma; orthopedics

(This special issue belongs to the Section Medical Research)

The Development and Application of Artificial Intelligence in Medical Imaging

edited by

Tiffany Y. So

submission deadline 30 Sep 2026 | Viewed by 155 | Submission Open

Keywords: artificial intelligence; medical imaging; development & application; clinical translation; workflow; evaluation

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Updates in Human Disease Genetic Research

edited by

Theru A. Sivakumaran

submission deadline 30 Sep 2026 | Viewed by 130 | Submission Open

Keywords: gene discovery; cancer biomarker discovery; GWAS; genetic testing; personalized therapy; genotype– phenotype correlations

(This special issue belongs to the Section Genomics and Proteomics)

Pathology, Diagnosis, and Treatments of Airway Diseases

edited by

Laura Bergantini

and

Tommaso Pianigiani

submission deadline 1 Oct 2026 | 4 articles | Viewed by 3038 | Submission Open

Keywords: airway diseases; COPD; asthma; cystic fibrosis; bronchiectasis; biomarkers; biologics; targeted; immunology; pathogenesis

(This special issue belongs to the Section Medical Research)

Innovations in Critical Care and Anesthesiology

edited by

Luigi La Via

submission deadline 2 Oct 2026 | 5 articles | Viewed by 4807 | Submission Open

Keywords: artificial intelligence in ICU; point-of-care monitoring; enhanced recovery protocols; precision anesthesia; mechanical ventilation; organ support systems; perioperative medicine; critical care innovations

(This special issue belongs to the Section Medical Research)

From Vessel to Muscle—an Integrative Approach to Ischemic Heart Disease

edited by

Irina Iuliana Costache Enache

Ciprian Rezus

and

Minerva Codruta Badescu

submission deadline 15 Oct 2026 | 2 articles | Viewed by 3466 | Submission Open

Keywords: ischemic heart disease; atherosclerotic plaque features; microvascular dysfunction; coronary vasospasm; percutaneous transluminal coronary angioplasty; coronary artery bypass grafting; cardiac magnetic resonance imaging; coronary computed tomography angiography

(This special issue belongs to the Section Physiology and Pathology)

Outlook for Cerebrovascular Damage Research

edited by Ane Claudia Fernandes Nunes

submission deadline 15 Oct 2026 | 1 articles | Viewed by 2362 | Submission Open

Keywords: intracerebral hemorrhage; microangiopathic disease; cerebral microhemorrhages blood– brain barrier; small vessel disease

(This special issue belongs to the Section Physiology and Pathology)

Point-of-Care Ultrasound (POCUS) in Nephrology

edited by Abhilash Koratala, Gregorio Romero-González and Aala Jaberi

submission deadline 16 Oct 2026 | Viewed by 224 | Submission Open

Keywords: point-of-care ultrasound; nephrology; doppler ultrasound; venous congestion; cardiorenal syndrome; volume assessment; acute kidney injury; dialysis

(This special issue belongs to the Section Medical Research)

Advances in Vascular Medicine: From Endovascular Innovations to Pathophysiological Insights

edited by

Edit Dósa

submission deadline 17 Oct 2026 | 4 articles | Viewed by 4004 | Submission Open

Keywords: endovascular therapy; vascular pathophysiology; intravascular imaging; atherosclerosis; precision vascular medicine

(This special issue belongs to the Section Medical Research)

2nd Edition—Food Microbiological Contamination

edited by

Sara Primavilla

and

Rossana Roila

submission deadline 18 Oct 2026 | 3 articles | Viewed by 3253 | Submission Open

Keywords: food safety; food microbiology; foodborne pathogens; food spoilage; food quality; food contamination; microbiological hazards; natural antimicrobials

(This special issue belongs to the Section Microbiology)

Antimicrobial Resistance as a Dynamic System: Behavior and Ecology from Pathogens to Populations

edited by

Kwabena O. Duedu

Jean Ralph Zahar

and

Eric Sampane-Donkor

submission deadline 18 Oct 2026 | Viewed by 72 | Submission Open

Keywords: antimicrobial resistance (AMR); environmental microbiology; epidemiology; phenotypic plasticity; microbial ecology; resistance dynamics; pathogen behavior

(This special issue belongs to the Section Microbiology)

Novel Liquid Biopsy Biomarkers and Multi-Omic Integration in Metabolic Diseases

edited by

Makrina Karaglani

submission deadline 20 Oct 2026 | 1 articles | Viewed by 5572 | Submission Open

Keywords: liquid biopsy; metabolic diseases; cell-free DNA; extracellular vesicles; multi-omics; biomarkers; epigenetics; machine learning; NAFLD

(This special issue belongs to the Section Medical Research)

Advanced Interventions in Diabetic Foot Ulcers

edited by

Florin Teodor Bobirca

Octavian Mihalache

and Petronel Mustatea

submission deadline 20 Oct 2026 | 1 articles | Viewed by 506 | Submission Open

Keywords: diabetic foot; gangrene; ulcer; peripheral arterial disease; peripheral neuropathy; Charcot foot; negative pressure

(This special issue belongs to the Section Medical Research)

Animal Reproduction and Health

edited by

Rachel Moxon

and

Ana Faustino

submission deadline 28 Oct 2026 | 4 articles | Viewed by 7952 | Submission Open

Keywords: animal; reproduction; genetics; heritability; disease; fertility; sperm; health; pregnancy; neonatal health and development; microbiome health and development

(This special issue belongs to the Section Animal Science)

Research Progress in Kidney Diseases

edited by Ane Claudia Fernandes Nunes

submission deadline 30 Oct 2026 | 10 articles | Viewed by 20036 | Submission Open

Keywords: chronic kidney disease; acute kidney injury; hemodialysis; nephrology; renal failure; hypertension; diabetes; molecular genetics

(This special issue belongs to the Section Physiology and Pathology)

New Horizons of Adipose Tissue Disorders: From Hormonal Issues to Loose Connective Disease: 2nd Edition

edited by

Laura Patton

and

Guido Gabriele

submission deadline 30 Oct 2026 | 5 articles | Viewed by 14790 | Submission Open

Keywords: adipose tissue; lipedema; lymphedema; obesity; matrix; vascular and lymphatic disorder; connective tissue diseases; dysbiosis; inflammation; pain

(This special issue belongs to the Section Medical Research)

Gut Microbes Associating with the Host

edited by

Jianmin Chai

and

Kun Li

submission deadline 30 Oct 2026 | 3 articles | Viewed by 8434 | Submission Open

Keywords: gut microbes; microbiome; animals; nutrition

(This special issue belongs to the Section Microbiology)

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