Special Issues

Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Myeloproliferative Neoplasms: From Biology to Practice
edited by Adrian Duek
submission deadline 31 Aug 2026 | Viewed by 41 | Submission Open
Keywords: polycythemia vera; essential thrombocythemia; primary myelofibrosis; JAK2 V617F calreticulin; MPL; next-generation sequencing; risk factor scores
(This special issue belongs to the Section Medical Research)
Molecular Regulation of Fruit Development in Solanaceous Crops: From Genes to Phenotypes
edited by , Wencai Yang and Ruohe Yin
submission deadline 31 Aug 2026 | Viewed by 39 | Submission Open
Keywords: Solanaceous crops; fruit development; omics; genetics; phenotype
(This special issue belongs to the Section Plant Science)
Nutritional Value and Stress Tolerance Mechanisms in Legume Crops
edited by Carlos Pimentel
submission deadline 31 Aug 2026 | Viewed by 23 | Submission Open
Keywords: water stress; temperature; salinity; stress adaptation; biological nitrogen fixation; grain quality; yield
(This special issue belongs to the Section Plant Science)
Novel Insights into Stress and Nutritional Regulation in Animals
edited by Hao-Yang Sun, , Zhan-Wei Teng and Xiao Liu
submission deadline 1 Sep 2026 | Viewed by 83 | Submission Open
Keywords: stress; nutrition; resilience; gut– X axis; microbiome; precision nutrition; multi-omics
(This special issue belongs to the Section Animal Science)
New Diagnostic and Therapeutic Developments in Eye and Systemic Diseases: 2nd Edition
edited by
submission deadline 1 Sep 2026 | Viewed by 12 | Submission Open
Keywords: eye diseases; systemic diseases; oculomics; ocular imaging; eye surgery; retina; cornea; glaucoma; refractive surgery; OCT; OCTA
(This special issue belongs to the Section Medical Research)
Plants: Emerging Bio-Manufacturing Chassis for Bioactive Molecules
edited by
submission deadline 15 Sep 2026 | Viewed by 77 | Submission Open
Keywords: plant biotechnology; metabolic engineering; secondary metabolite; recombinant proteins; synthetic biology; biopharmaceuticals; plant cell culture; molecular farming
(This special issue belongs to the Section Plant Science)
Translational Neuro-Oncology: Molecular Insights, Bioinformatics, and Technological Innovations
edited by Felix Mircea Brehar
submission deadline 20 Sep 2026 | Viewed by 130 | Submission Open
Keywords: translational neuro-oncology; central nervous system tumors; molecular and cellular mechanisms; multi-omics and biomarkers; bioinformatics and systems biology; artificial intelligence in medicine; radiomics and radiogenomics; precision neurosurgery; experimental and clinical research; therapeutic innovation in neuro-oncology
(This special issue belongs to the Section Physiology and Pathology)
Mucosal Immunity and Immune Memory: The New Frontier in Vaccination and Immunopathology
edited by
submission deadline 20 Sep 2026 | Viewed by 79 | Submission Open
Keywords: mucosal immunity; hybrid immunity; next-generation vaccines; artificial intelligence; neo-adjuvants; clinical trial; case studies
(This special issue belongs to the Section Medical Research)
Imaging and Analysis of Microbial Motility: From Single Cells to Communities
edited by
submission deadline 20 Sep 2026 | Viewed by 61 | Submission Open
Keywords: motility; cell tracking; biofilm; swimming; swarming; Archaea; flagella
(This special issue belongs to the Section Microbiology)
Prebiotic RNA: From Autocatalysis and Chirality to Functional Evolution
edited by
submission deadline 20 Sep 2026 | Viewed by 61 | Submission Open
Keywords: RNA; origin of life; replication; autocatalysis; chirality; ribozymes; metabolism
(This special issue belongs to the Section Origin of Life)
Microbiome Engineering for Sustainable Pest Control Under Climate Change
edited by Abdul Basit and
submission deadline 20 Sep 2026 | Viewed by 52 | Submission Open
Keywords: microbiome engineering; climate-smart pest management; systems biology; One Health; sustainable agriculture; microbial ecology; plant resilience; climate change; beneficial microbes; evolutionary biology; environmental sustainability; agricultural ecosystems; microbial communities
(This special issue belongs to the Section Microbiology)
Spotlight on Veterinary Pathology and Toxicology
edited by and Mario Darius Codreanu
submission deadline 25 Sep 2026 | Viewed by 37 | Submission Open
Keywords: veterinary pathology; toxicology; advanced diagnostic techniques; pathogenesis; public health
(This special issue belongs to the Section Animal Science)
Pathogenesis and Novel Treatment for Kidney Diseases
edited by
submission deadline 25 Sep 2026 | Viewed by 32 | Submission Open
Keywords: molecular mechanisms of kidney disease; pathophysiology of renal injury; inflammation and fibrosis in kidney disease; novel therapeutic targets; precision medicine in nephrology; translational approaches in renal disease
(This special issue belongs to the Section Medical Research)
Plant Life: Integrating Multi-Omic Approaches from Molecules to Environment
edited by and Fang He
submission deadline 25 Sep 2026 | Viewed by 31 | Submission Open
Keywords: plant physiology; multi-omics integration; ionomics; genomics; transcriptomics; metabolomics; proteomics; epigenetics; single-cell analysis; environmental stress; molecular mechanisms; systems biology
(This special issue belongs to the Section Plant Science)
Mitochondrial and Endoplasmic Reticulum Dynamics in Cellular Stress Responses
edited by , Xing Duan and
submission deadline 25 Sep 2026 | Submission Open
Keywords: mitochondria; endoplasmic reticulum; MAMs; cellular responses; physiopathology; homeostasis; cross-talk; stress; signaling; regulation
(This special issue belongs to the Section Physiology and Pathology)
Natural Products and Modern Drug Discovery: Emerging Strategies Targeting Cancer- and Disease-Related Molecular Mechanisms
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 3379 | Submission Open
Keywords: natural products; phytochemicals; drug discovery; bioactivity profiling; pharmacophore modeling; synthetic biology; cancer therapy; microbial metabolites
(This special issue belongs to the Section Medical Research)
Research Updates in Hematology
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1215 | Submission Open
Keywords: antiphospholipid syndrome; complement; endothelium; hemoglobinopathies; hemophilia; leukemias; lymphomas; multiple myeloma; pediatric hematology; thrombosis
(This special issue belongs to the Section Physiology and Pathology)
Parasite Detection, Control Strategies and Risk Factors Related to Reproductive Health in Livestock submission deadline 30 Sep 2026 | Viewed by 583 | Submission Open
Keywords: livestock; parasite control; reproductive health; management
(This special issue belongs to the Section Animal Science)
Ocular Diseases: Mechanisms, Diagnostics, and Emerging Therapeutic Strategies
edited by Joanna Dolar-Szczasny
submission deadline 30 Sep 2026 | 1 articles | Viewed by 366 | Submission Open
Keywords: molecular mechanisms of eye disease; oxidative stress and inflammation; neurodegeneration in vision; ocular biomarkers; pharmacological therapies; gene therapy; stem cell and regenerative approaches; precision/personalized ophthalmology
(This special issue belongs to the Section Medical Research)
Genetic Regulation of Natural Product Biosynthesis in Medicinal Plants
edited by and Lin Cheng
submission deadline 30 Sep 2026 | Viewed by 161 | Submission Open
Keywords: medicinal plants; natural products; biosynthesis; genetic regulation; transcription factors; multi-omics; metabolic engineering; specialized metabolism
(This special issue belongs to the Section Plant Science)
Molecular Underpinnings of Cancer: Pathways to Targeted Therapy submission deadline 30 Sep 2026 | Viewed by 141 | Submission Open
Keywords: signaling pathways; tumor microenvironment; cancer metabolism; biomarkers; drug resistance; precision medicine; targeted therapy
(This special issue belongs to the Section Medical Research)
Neurorehabilitation: Technology-Driven Recovery and Functional Rewiring
edited by
submission deadline 30 Sep 2026 | Viewed by 138 | Submission Open
Keywords: cognitive-motor recovery; neuroplasticity; multidimensional assessment; post-stroke rehabilitation
(This special issue belongs to the Section Medical Research)
Women's Health and Well-Being: A Focus on Obstetrics and Gynecologic Medicine
edited by Luca Roncati
submission deadline 30 Sep 2026 | Viewed by 132 | Submission Open
Keywords: women’ s health; gynecology; gynecopathology; preventive gynecological oncology; senology; breast cancer; cervical cancer; sexually transmitted infections; human papillomavirus; autoimmune diseases
(This special issue belongs to the Section Medical Research)
Cognitive and Imaging Mechanisms in Neurological Disorders
edited by Foteini Christidi, and
submission deadline 30 Sep 2026 | Viewed by 129 | Submission Open
Keywords: neurological disorders; cognitive dysfunction; neuropsychological assessment; neuroimaging; structural MRI; functional MRI; multimodal neuroimaing; biomarkers; machine learning in neurology; neurorehabilitation
(This special issue belongs to the Section Medical Research)
Biomarkers in Ischemic Stroke: From Discovery to Clinical Applications
edited by Hock-Kean Liew
submission deadline 30 Sep 2026 | Viewed by 123 | Submission Open
Keywords: ischemic stroke; biomarkers; neuroinflammation; oxidative stress; excitotoxicity; thrombolysis; mechanical thrombectomy; blood– brain barrier; neuroprotection; precision medicine
(This special issue belongs to the Section Medical Research)
Advanced Optical Imaging for Tissue and Tumour Characterization
edited by and Ana Teresa A. Amaral
submission deadline 30 Sep 2026 | Viewed by 104 | Submission Open
Keywords: optical imaging; label-free imaging; functional imaging; multimodal imaging; tissue characterization; tumour microenvironment; tumour heterogeneity; extracellular matrix; therapeutic monitoring
(This special issue belongs to the Section Medical Research)
Advanced Research in Plant–Pathogen Interactions
edited by and
submission deadline 30 Sep 2026 | Viewed by 98 | Submission Open
Keywords: plant-pathogen interaction; plant immunity; pathogen effectors; host defense mechanisms; autophagy; noncoding RNA; small peptides; molecular plant pathology; crop disease resistance
(This special issue belongs to the Section Plant Science)
Pathophysiology, Diagnosis, and Treatments of Intestinal Diseases—2nd Edition
edited by Amosy Ephreim M’Koma
submission deadline 30 Sep 2026 | Viewed by 83 | Submission Open
Keywords: gastrointestinal disease/disorders; pathophysiology; diagnostics and treatment
(This special issue belongs to the Section Physiology and Pathology)
The Oral-Systemic Link in Chronic Mucosal Diseases
edited by
submission deadline 30 Sep 2026 | Viewed by 67 | Submission Open
Keywords: oral diseases; general diseases; biomarkers
(This special issue belongs to the Section Medical Research)
Latest Research Updates on Laparoscopy
edited by Niculae N. Iordache and Claudiu-Octavian Ungureanu
submission deadline 30 Sep 2026 | Viewed by 56 | Submission Open
Keywords: laparoscopy; minimally invasive surgery; surgical innovation; imaging and navigation; artificial intelligence in surgery; surgical outcomes; clinical advancements
(This special issue belongs to the Section Medical Research)
Synthetic Biology and Biotechnology Application of Algae
edited by Fantao Kong and
submission deadline 30 Sep 2026 | Viewed by 51 | Submission Open
Keywords: synthetic biology; algal biotechnology; metabolic engineering; biofuels; carbon capture; high-value products; genetic tools; bioremediation
(This special issue belongs to the Section Synthetic Biology and Systems Biology)
Biomaterials for Antimicrobial Applications submission deadline 30 Sep 2026 | Viewed by 42 | Submission Open
Keywords: antimicrobial biomaterials; translational materials; antifouling and antibiofilm surfaces; antimicrobial coatings; controlled release; diagnostic materials; implant surfaces; infection-resistant implants; wound healing and tissue engineering
(This special issue belongs to the Section Microbiology)
New Challenges in Fracture Management
edited by
submission deadline 30 Sep 2026 | Viewed by 24 | Submission Open
Keywords: fracture; extremity trauma; orthopedic trauma; orthopedics
(This special issue belongs to the Section Medical Research)
Gender Medicine in Dermatology, Rheumatology and Immunology
edited by
submission deadline 30 Sep 2026 | Viewed by 20 | Submission Open
Keywords: gender medicine; sex and gender differences; immune-mediated diseases; autoimmunity and inflammation; dermatology; rheumatology; immunology
(This special issue belongs to the Section Medical Research)
Rhizosphere Microbiomes and Plant Adaptation Mechanisms to Abiotic Stressors
edited by Ligang Qin
submission deadline 30 Sep 2026 | Viewed by 1 | Submission Open
Keywords: rhizosphere microbiome; abiotic stress; saline– alkaline grassland; ecological restoration; salt– alkali tolerant grass species; plant– microbe interactions
(This special issue belongs to the Section Plant Science)
Updates in Human Disease Genetics Research
edited by Theru A. Sivakumaran
submission deadline 30 Sep 2026 | Viewed by 1 | Submission Open
Keywords: gene discovery; cancer biomarker discovery; GWAS; genetic testing; personalized therapy; genotype– phenotype correlations
(This special issue belongs to the Section Genetics and Genomics)
Pathology, Diagnosis, and Treatments of Airway Diseases submission deadline 1 Oct 2026 | 1 articles | Viewed by 957 | Submission Open
Keywords: airway diseases; COPD; asthma; cystic fibrosis; bronchiectasis; biomarkers; biologics; targeted; immunology; pathogenesis
(This special issue belongs to the Section Medical Research)
Innovations in Critical Care and Anesthesiology
edited by
submission deadline 2 Oct 2026 | 1 articles | Viewed by 903 | Submission Open
Keywords: artificial intelligence in ICU; point-of-care monitoring; enhanced recovery protocols; precision anesthesia; mechanical ventilation; organ support systems; perioperative medicine; critical care innovations
(This special issue belongs to the Section Medical Research)
Outlook for Cerebrovascular Damage Research
edited by Ane Claudia Fernandes Nunes
submission deadline 15 Oct 2026 | 1 articles | Viewed by 1784 | Submission Open
Keywords: intracerebral hemorrhage; microangiopathic disease; cerebral microhemorrhages blood– brain barrier; small vessel disease
(This special issue belongs to the Section Physiology and Pathology)
Novel Liquid Biopsy Biomarkers and Multi-Omic Integration in Metabolic Diseases
edited by
submission deadline 20 Oct 2026 | 1 articles | Viewed by 4549 | Submission Open
Keywords: liquid biopsy; metabolic diseases; cell-free DNA; extracellular vesicles; multi-omics; biomarkers; epigenetics; machine learning; NAFLD
(This special issue belongs to the Section Medical Research)
Animal Reproduction and Health
edited by and
submission deadline 28 Oct 2026 | 4 articles | Viewed by 4883 | Submission Open
Keywords: animal; reproduction; genetics; heritability; disease; fertility; sperm; health; pregnancy; neonatal health and development; microbiome health and development
(This special issue belongs to the Section Animal Science)
Research Progress in Kidney Diseases
edited by Ane Claudia Fernandes Nunes
submission deadline 30 Oct 2026 | 5 articles | Viewed by 9648 | Submission Open
Keywords: chronic kidney disease; acute kidney injury; hemodialysis; nephrology; renal failure; hypertension; diabetes; molecular genetics
(This special issue belongs to the Section Physiology and Pathology)
Artificial Intelligence in Head and Neck Cancer Radiotherapy and Imaging
edited by Elias Liolis
submission deadline 30 Oct 2026 | Viewed by 87 | Submission Open
Keywords: head and neck cancer; treatment planning; radiotherapy; oral cavity cancer; PET-CT imaging
(This special issue belongs to the Section Medical Research)
The Management and Prognosis of Open-Angle Glaucoma
edited by
submission deadline 31 Oct 2026 | 2 articles | Viewed by 2859 | Submission Open
Keywords: open-angle glaucoma; cataracts; visual impairment
(This special issue belongs to the Section Medical Research)
The Roles and Regulation of RECK in Cell Behavior, Animal Development, and Diseases submission deadline 31 Oct 2026 | 1 articles | Viewed by 293 | Submission Open
Keywords: cancer; metastasis; cell migration; angiogenesis; neurogenesis; extracellular matrix; disease models
(This special issue belongs to the Section Physiology and Pathology)
Pharmacotherapy in Critical Care: Clinical Insight and Emerging Strategy
edited by
submission deadline 31 Oct 2026 | Viewed by 152 | Submission Open
Keywords: sepsis; multidrug resistance; extracorporeal treatments; intracranial hypertension; immunomodulation; organ support; precision medicine; intensive care pharmacology
(This special issue belongs to the Section Medical Research)
Precision Approaches in Solid Tumor Oncology: From Molecular Pathways to Therapy Response
edited by and Luís Ortega-Medina
submission deadline 31 Oct 2026 | Viewed by 86 | Submission Open
Keywords: biomarkers; histology; immunohistochemistry; solid tumors; precision oncology; therapy response
(This special issue belongs to the Section Medical Research)
Machine Learning for Biomedical and Clinical Informatics: From Data-Driven Methods to Translational Medical Research
edited by and Kalpana Raja
submission deadline 31 Oct 2026 | Viewed by 40 | Submission Open
Keywords: biomedical informatics; translational medical research; clinical informatics; causal inference in health data; machine learning in healthcare; electronic health records (EHR); natural language processing; large language models; artificial intelligence in medicine; explainable and trustworthy AI
(This special issue belongs to the Section Medical Research)
Otolaryngology and Sleep Medicine: From Precision Diagnosis to Advanced Therapeutics
edited by
submission deadline 28 Nov 2026 | Viewed by 104 | Submission Open
Keywords: sleep-disordered breathing; otolaryngology; sleep medicine; pulmonology; neurology
(This special issue belongs to the Section Medical Research)
Advances on Physiotherapy and Functional Rehabilitation in Chronic Conditions
edited by
submission deadline 30 Nov 2026 | 1 articles | Viewed by 226 | Submission Open
Keywords: physiotherapy; chronic condition; functionality; pain
(This special issue belongs to the Section Medical Research)
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