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Citations	Article
425	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
126	Brain Tumor Classification Using Meta-Heuristic Optimized Convolutional Neural Networks by Sarah Zuhair Kurdi, Mohammed Hasan Ali, Mustafa Musa Jaber, Tanzila Saba, Amjad Rehman and Robertas Damaševičius
101	Predicting the Onset of Diabetes with Machine Learning Methods by Chun-Yang Chou, Ding-Yang Hsu and Chun-Hung Chou
97	Advancing Patient Care: How Artificial Intelligence Is Transforming Healthcare by Diana Gina Poalelungi, Carmina Liana Musat, Ana Fulga, Marius Neagu, Anca Iulia Neagu, Alin Ionut Piraianu and Iuliu Fulga
87	Ethical Conundrums in the Application of Artificial Intelligence (AI) in Healthcare—A Scoping Review of Reviews by Sreenidhi Prakash, Jyotsna Needamangalam Balaji, Ashish Joshi and Krishna Mohan Surapaneni
84	Type 1 Diabetes Mellitus and Autoimmune Diseases: A Critical Review of the Association and the Application of Personalized Medicine by Mihaela Simona Popoviciu, Nirja Kaka, Yashendra Sethi, Neil Patel, Hitesh Chopra and Simona Cavalu
79	Perception about Health Applications (Apps) in Smartphones towards Telemedicine during COVID-19: A Cross-Sectional Study by Lingala Kalyan Viswanath Reddy, Pallavi Madithati, Bayapa Reddy Narapureddy, Sahithya Ravali Ravula, Sunil Kumar Vaddamanu, Fahad Hussain Alhamoudi, Giuseppe Minervini and Saurabh Chaturvedi
64	The Penn Medicine BioBank: Towards a Genomics-Enabled Learning Healthcare System to Accelerate Precision Medicine in a Diverse Population by Anurag Verma, Scott M. Damrauer, Nawar Naseer, JoEllen Weaver, Colleen M. Kripke, Lindsay Guare, Giorgio Sirugo, Rachel L. Kember, Theodore G. Drivas, Scott M. Dudek, Yuki Bradford, Anastasia Lucas, Renae Judy, Shefali S. Verma, Emma Meagher, Katherine L. Nathanson, Michael Feldman, Marylyn D. Ritchie, Daniel J. Rader and For The Penn Medicine BioBank
63	The Role of BDNF as a Biomarker in Cognitive and Sensory Neurodegeneration by Anna Pisani, Fabiola Paciello, Valeria Del Vecchio, Rita Malesci, Eugenio De Corso, Elena Cantone and Anna Rita Fetoni
62	Personalised Medicine—Implementation to the Healthcare System in Europe (Focus Group Discussions) by Dorota Stefanicka-Wojtas and Donata Kurpas

Citations	Article
50	miRNA-Based Technologies in Cancer Therapy by Maria Pagoni, Claudia Cava, Diamantis C. Sideris, Margaritis Avgeris, Vassilios Zoumpourlis, Ioannis Michalopoulos and Nikolaos Drakoulis
42	Microbiome Dynamics: A Paradigm Shift in Combatting Infectious Diseases by Mohamed Kamel, Sami Aleya, Majed Alsubih and Lotfi Aleya
39	Assessment of Quality and Readability of Information Provided by ChatGPT in Relation to Anterior Cruciate Ligament Injury by Stephen Fahy, Stephan Oehme, Danko Milinkovic, Tobias Jung and Benjamin Bartek
38	The Promise of Explainable AI in Digital Health for Precision Medicine: A Systematic Review by Ben Allen
37	Decrease in Sperm Parameters in the 21st Century: Obesity, Lifestyle, or Environmental Factors? An Updated Narrative Review by Romualdo Sciorio, Luca Tramontano, Mohammed Adel and Steven Fleming
36	Patient-Generated Health Data (PGHD): Understanding, Requirements, Challenges, and Existing Techniques for Data Security and Privacy by Pankaj Khatiwada, Bian Yang, Jia-Chun Lin and Bernd Blobel
35	Digital Twins’ Advancements and Applications in Healthcare, Towards Precision Medicine by Konstantinos Papachristou, Paraskevi F. Katsakiori, Panagiotis Papadimitroulas, Lidia Strigari and George C. Kagadis
34	Breaking Barriers—The Intersection of AI and Assistive Technology in Autism Care: A Narrative Review by Antonio Iannone and Daniele Giansanti
33	The Application of Radiomics and AI to Molecular Imaging for Prostate Cancer by William Tapper, Gustavo Carneiro, Christos Mikropoulos, Spencer A. Thomas, Philip M. Evans and Stergios Boussios
31	Parvovirus B19 Infection and Pregnancy: Review of the Current Knowledge by Fernanda Parciasepe Dittmer, Clara de Moura Guimarães, Alberto Borges Peixoto, Karina Felippe Monezi Pontes, Maria Paola Bonasoni, Gabriele Tonni and Edward Araujo Júnior

Citations	Article
35	Digital Twins’ Advancements and Applications in Healthcare, Towards Precision Medicine by Konstantinos Papachristou, Paraskevi F. Katsakiori, Panagiotis Papadimitroulas, Lidia Strigari and George C. Kagadis
30	AI-Reinforced Wearable Sensors and Intelligent Point-of-Care Tests by Ghita Yammouri and Abdellatif Ait Lahcen
16	A Talk with ChatGPT: The Role of Artificial Intelligence in Shaping the Future of Cardiology and Electrophysiology by Angelica Cersosimo, Elio Zito, Nicola Pierucci, Andrea Matteucci and Vincenzo Mirco La Fazia
14	A Novel CNN-Based Framework for Alzheimer’s Disease Detection Using EEG Spectrogram Representations by Konstantinos Stefanou, Katerina D. Tzimourta, Christos Bellos, Georgios Stergios, Konstantinos Markoglou, Emmanouil Gionanidis, Markos G. Tsipouras, Nikolaos Giannakeas, Alexandros T. Tzallas and Andreas Miltiadous
12	Advances in mRNA LNP-Based Cancer Vaccines: Mechanisms, Formulation Aspects, Challenges, and Future Directions by Eslam Ramadan, Ali Ahmed and Youssef Wahib Naguib
10	The Future of Pharmacogenomics: Integrating Epigenetics, Nutrigenomics, and Beyond by Jeffrey A. Shaman
10	The Role of Artificial Intelligence and Emerging Technologies in Advancing Total Hip Arthroplasty by Luca Andriollo, Aurelio Picchi, Giulio Iademarco, Andrea Fidanza, Loris Perticarini, Stefano Marco Paolo Rossi, Giandomenico Logroscino and Francesco Benazzo
9	Opportunities and Challenges of Chatbots in Ophthalmology: A Narrative Review by Mehmet Cem Sabaner, Rodrigo Anguita, Fares Antaki, Michael Balas, Lars Christian Boberg-Ans, Lorenzo Ferro Desideri, Jakob Grauslund, Michael Stormly Hansen, Oliver Niels Klefter, Ivan Potapenko, Marie Louise Roed Rasmussen and Yousif Subhi
8	Left Atrial Strain: State of the Art and Clinical Implications by Niloofar Javadi, Nadera N. Bismee, Mohammed Tiseer Abbas, Isabel G. Scalia, Milagros Pereyra, Nima Baba Ali, Sogol Attaripour Esfahani, Kamal Awad, Juan M. Farina, Chadi Ayoub and Reza Arsanjani
7	The Effects of Resistance Training on Pain, Strength, and Function in Osteoarthritis: Systematic Review and Meta-Analysis by Jaehyun Lim, Ahyoung Choi and Byeonggeun Kim

Citations	Article
16	A Talk with ChatGPT: The Role of Artificial Intelligence in Shaping the Future of Cardiology and Electrophysiology by Angelica Cersosimo, Elio Zito, Nicola Pierucci, Andrea Matteucci and Vincenzo Mirco La Fazia
4	Digital Twin Models in Atrial Fibrillation: Charting the Future of Precision Therapy? by Paschalis Karakasis, Antonios P. Antoniadis, Panagiotis Theofilis, Panayotis K. Vlachakis, Nikias Milaras, Dimitrios Patoulias, Theodoros Karamitsos and Nikolaos Fragakis
3	Patient-Derived Organoid Biobanks for Translational Research and Precision Medicine: Challenges and Future Perspectives by Floriana Jessica Di Paola, Giulia Calafato, Pier Paolo Piccaluga, Giovanni Tallini and Kerry Jane Rhoden
2	Temporary Mechanical Support in Cardiogenic Shock Secondary to Heart Failure: An Evolving Paradigm by Nandini Nair, Dongping Du and Balakrishnan Mahesh
2	The Impact of AI-Driven Chatbot Assistance on Protocol Development and Clinical Research Engagement: An Implementation Report by Kusal Weerasinghe, David B. Olawade, Jennifer Teke, Maines Msiska and Stergios Boussios
2	Prophylactic and Therapeutic Usage of Drains in Gynecologic Oncology Procedures: A Comprehensive Review by Chrysoula Margioula-Siarkou, Aristarchos Almperis, Emmanouela-Aliki Almperi, Georgia Margioula-Siarkou, Stefanos Flindris, Nikoletta Daponte, Alexandros Daponte, Konstantinos Dinas and Stamatios Petousis
2	Artificial Intelligence in the Assessment and Grading of Acne Vulgaris: A Systematic Review by Daniele Omar Traini, Gerardo Palmisano, Cristina Guerriero and Ketty Peris
2	Advanced Basal Cell Carcinoma: A Narrative Review on Current Systemic Treatments and the Neoadjuvant Approach by Andrea Paradisi, Maria Mannino, Francesco Brunetti, Enrico Bocchino, Alessandro Di Stefani and Ketty Peris
2	Radiological Assessment After Pancreaticoduodenectomy for a Precision Approach to Managing Complications: A Narrative Review by Fabrizio Urraro, Vittorio Patanè, Alfredo Clemente, Nicoletta Giordano, Damiano Caputo, Roberto Cammarata, Gianluca Costa and Alfonso Reginelli
2	Psychological Traits of Bariatric Surgery Candidates and Predictors of Outcomes by Abed Hadipour Lakmehsari, Carmela Mento, Claudia Scaramuzzino, Federica Arena, Fabrizio Turiaco, Maria Rosaria Anna Muscatello, Giuseppe Navarra, Gianluca Pandolfo and Clara Lombardo

Citations	Article
681	The Enhanced Permeability and Retention (EPR) Effect: The Significance of the Concept and Methods to Enhance Its Application by Jun Wu
490	Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort by Anna Shcherbina, C. Mikael Mattsson, Daryl Waggott, Heidi Salisbury, Jeffrey W. Christle, Trevor Hastie, Matthew T. Wheeler and Euan A. Ashley
456	Recent Advances in Tumor Targeting via EPR Effect for Cancer Treatment by Md Abdus Subhan, Satya Siva Kishan Yalamarty, Nina Filipczak, Farzana Parveen and Vladimir P. Torchilin
454	Global Challenges to Public Health Care Systems during the COVID-19 Pandemic: A Review of Pandemic Measures and Problems by Roxana Filip, Roxana Gheorghita Puscaselu, Liliana Anchidin-Norocel, Mihai Dimian and Wesley K. Savage
425	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
383	Digital Twins: From Personalised Medicine to Precision Public Health by Maged N. Kamel Boulos and Peng Zhang
334	Breast Cancer Treatments: Updates and New Challenges by Anna Burguin, Caroline Diorio and Francine Durocher
331	Health 2050: The Realization of Personalized Medicine through Crowdsourcing, the Quantified Self, and the Participatory Biocitizen by Melanie Swan
283	Applications of Machine Learning Predictive Models in the Chronic Disease Diagnosis by Gopi Battineni, Getu Gamo Sagaro, Nalini Chinatalapudi and Francesco Amenta
220	Gallstone Disease, Obesity and the Firmicutes/Bacteroidetes Ratio as a Possible Biomarker of Gut Dysbiosis by Irina N. Grigor’eva

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67450	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
61917	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
43232	Neuropsychiatric Manifestations of Mast Cell Activation Syndrome and Response to Mast-Cell-Directed Treatment: A Case Series by Leonard B. Weinstock, Renee M. Nelson and Svetlana Blitshteyn
38233	Fenugreek and Its Effects on Muscle Performance: A Systematic Review by Waleed I. Albaker
37652	Effects of Red and Infrared Laser Therapy in Patients with Tinnitus: A Double-Blind, Clinical, Randomized Controlled Study Combining Light with Ultrasound, Drugs and Vacuum Therapy by Vitor Hugo Panhóca, Antônio Eduardo de Aquino Junior, Viviane Brocca de Souza, Simone Aparecida Ferreira, Lais Tatiane Ferreira, Karina Jullienne de Oliveira Souza, Patricia Eriko Tamae, Marcelo Saito Nogueira and Vanderlei Salvador Bagnato
37546	Vasopressin in Sepsis and Other Shock States: State of the Art by Raquel García-Álvarez and Rafael Arboleda-Salazar
26439	Type 1 Diabetes Mellitus and Autoimmune Diseases: A Critical Review of the Association and the Application of Personalized Medicine by Mihaela Simona Popoviciu, Nirja Kaka, Yashendra Sethi, Neil Patel, Hitesh Chopra and Simona Cavalu
25493	Management of Hyponatremia in Heart Failure: Practical Considerations by Victoriţa Şorodoc, Andreea Asaftei, Gabriela Puha, Alexandr Ceasovschih, Cătălina Lionte, Oana Sîrbu, Cristina Bologa, Raluca Ecaterina Haliga, Mihai Constantin, Adorata Elena Coman, Ovidiu Rusalim Petriș, Alexandra Stoica and Laurenţiu Şorodoc
23826	Ratings of the Effectiveness of 13 Therapeutic Diets for Autism Spectrum Disorder: Results of a National Survey by Julie S. Matthews and James B. Adams
23295	Long COVID Is Not a Functional Neurologic Disorder by Todd E. Davenport, Svetlana Blitshteyn, Nicola Clague-Baker, David Davies-Payne, Glenn J. Treisman and Sarah F. Tyson

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67450	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
23295	Long COVID Is Not a Functional Neurologic Disorder by Todd E. Davenport, Svetlana Blitshteyn, Nicola Clague-Baker, David Davies-Payne, Glenn J. Treisman and Sarah F. Tyson
19417	Folate Receptor Alpha Autoantibodies in the Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections (PANDAS) Population by Lindsey Wells, Nancy O’Hara, Richard E. Frye, Neeshi Hullavard and Erica Smith
17103	Binding Folate Receptor Alpha Autoantibody Is a Biomarker for Leucovorin Treatment Response in Autism Spectrum Disorder by Richard E. Frye, Patrick J. McCarty, Brianna A. Werner, Adrienne C. Scheck, Heidi L. Collins, Steven J. Adelman, Daniel A. Rossignol and Edward V. Quadros
16597	Possible Role of Fibrinaloid Microclots in Postural Orthostatic Tachycardia Syndrome (POTS): Focus on Long COVID by Douglas B. Kell, Muhammed Asad Khan, Binita Kane, Gregory Y. H. Lip and Etheresia Pretorius
14022	How Sex Hormones Affect Migraine: An Interdisciplinary Preclinical Research Panel Review by Frederick Godley III, John Meitzen, Hadas Nahman-Averbuch, Mary Angela O’Neal, David Yeomans, Nanette Santoro, Nina Riggins and Lars Edvinsson
13676	Leveraging Machine Learning for Personalized Wearable Biomedical Devices: A Review by Ali Olyanasab and Mohsen Annabestani
13524	Diagnosis, Prevention, and Management of Fetal Growth Restriction (FGR) by Panagiotis Tsikouras, Panos Antsaklis, Konstantinos Nikolettos, Sonia Kotanidou, Nektaria Kritsotaki, Anastasia Bothou, Sotiris Andreou, Theopi Nalmpanti, Kyriaki Chalkia, Vlasis Spanakis, George Iatrakis and Nikolaos Nikolettos
13323	Parvovirus B19 Infection and Pregnancy: Review of the Current Knowledge by Fernanda Parciasepe Dittmer, Clara de Moura Guimarães, Alberto Borges Peixoto, Karina Felippe Monezi Pontes, Maria Paola Bonasoni, Gabriele Tonni and Edward Araujo Júnior
13275	The Promise of Explainable AI in Digital Health for Precision Medicine: A Systematic Review by Ben Allen

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11663	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
10534	Advances in mRNA LNP-Based Cancer Vaccines: Mechanisms, Formulation Aspects, Challenges, and Future Directions by Eslam Ramadan, Ali Ahmed and Youssef Wahib Naguib
8181	Digital Twins’ Advancements and Applications in Healthcare, Towards Precision Medicine by Konstantinos Papachristou, Paraskevi F. Katsakiori, Panagiotis Papadimitroulas, Lidia Strigari and George C. Kagadis
7899	AI-Reinforced Wearable Sensors and Intelligent Point-of-Care Tests by Ghita Yammouri and Abdellatif Ait Lahcen
7728	Redefining Non-Motor Symptoms in Parkinson’s Disease by Laura Peña-Zelayeta, Karen M. Delgado-Minjares, Marcos M. Villegas-Rojas, Karen León-Arcia, Alberto Santiago-Balmaseda, Jesús Andrade-Guerrero, Isaac Pérez-Segura, Emmanuel Ortega-Robles, Luis O. Soto-Rojas and Oscar Arias-Carrión
7649	Exploring the Immunological Role of the Microbial Composition of the Appendix and the Associated Risks of Appendectomies by Tarequl Islam, Md Shahjalal Sagor, Noshin Tabassum Tamanna, Md Kamrul Islam Bappy, Danishuddin, Md Azizul Haque and Maximilian Lackner
7595	Occlusion and Biomechanical Risk Factors in Implant-Supported Full-Arch Fixed Dental Prostheses—Narrative Review by Andrea Berzaghi, Tiziano Testori, Riccardo Scaini and Sergio Bortolini
6818	The Effects of Resistance Training on Pain, Strength, and Function in Osteoarthritis: Systematic Review and Meta-Analysis by Jaehyun Lim, Ahyoung Choi and Byeonggeun Kim
6682	Genetic and Regulatory Mechanisms of Comorbidity of Anxiety, Depression and ADHD: A GWAS Meta-Meta-Analysis Through the Lens of a System Biological and Pharmacogenomic Perspective in 18.5 M Subjects by Kai-Uwe Lewandrowski, Kenneth Blum, Alireza Sharafshah, Kyriaki Z. Thanos, Panayotis K. Thanos, Richa Zirath, Albert Pinhasov, Abdalla Bowirrat, Nicole Jafari, Foojan Zeine, Milan Makale, Colin Hanna, David Baron, Igor Elman, Edward J. Modestino, Rajendra D. Badgaiyan, Keerthy Sunder, Kevin T. Murphy, Ashim Gupta, Alex P. L. Lewandrowski, Rossano Kepler Alvim Fiorelli and Sergio Schmidt Show full author list Hide full author list
6590	Concussion and the Autonomic, Immune, and Endocrine Systems: An Introduction to the Field and a Treatment Framework for Persisting Symptoms by Jon L. Pertab, Tricia L. Merkley, Holly Winiarski, Kelly M. J. Cramond and Alex J. Cramond

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11663	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
5942	The Exchange Breathing Method for Seizure Intervention: A Historical and Scientific Review of Epilepsy and Its Evolving Therapeutic Paradigms by Frederick Robert Carrick, Pamela Daniels, Stephen Pelletier, Sofia Prysmakova, Ahmed Hankir, Mahera Abdulrahman and Nouf Al-Rumaihi
5191	Effectiveness of Psychological Therapy for Treatment-Resistant Depression in Adults: A Systematic Review and Meta-Analysis by Sabrina Giguère, Alexandra Fortier, Julie Azrak, Charles-Édouard Giguère, Stéphane Potvin and Alexandre Dumais
4408	The Accuracy of ChatGPT-4o in Interpreting Chest and Abdominal X-Ray Images by Pietro G. Lacaita, Malik Galijasevic, Michael Swoboda, Leonhard Gruber, Yannick Scharll, Fabian Barbieri, Gerlig Widmann and Gudrun M. Feuchtner
3892	Right Ventricular Strain by Echocardiography: Current Clinical Applications and Future Directions for Mechanics Assessment of the Forgotten Ventricle by Mahmoud Abdelnabi, Ramzi Ibrahim, Hoang Nhat Pham, Bobbi Jo Heon, George Bcharah, Girish Pathangey, Milagros Pereyra Pietri, Juan M. Farina, Ian C. Chang, Reza Arsanjani and Chadi Ayoub
3788	Shoulder and Scapular Function Before and After a Scapular Therapeutic Exercise Program for Chronic Shoulder Pain and Scapular Dyskinesis: A Pre–Post Single-Group Study by Ana S. C. Melo, Ana L. Soares, Catarina Castro, Ricardo Matias, Eduardo B. Cruz, J. Paulo Vilas-Boas and Andreia S. P. Sousa
3490	PRP Therapy for Stress Urinary Incontinence and Pelvic Organ Prolapse: A New Frontier in Personalized Treatment? by Anna Pitsillidi, Laura Vona, Stefano Bettocchi, Sven Schiermeier and Günter Karl Noé
3305	*Major Allele Frequencies in CYP2C9* and CYP2C19 in Asian and European Populations: A Case Study to Disaggregate Data Among Large Racial Categories by Horng-Ee Vincent Nieh and Youssef Malak Roman**
3163	Comprehensive Management of Cocaine-Induced Midline Destructive Lesions: A Young-IfOS Consensus by Alberto Maria Saibene, Letizia Nitro, Florent Carsuzaa, Mihaela Alexandru, Vincent Bedarida, Matteo Di Bari, Léa Fath, Ainhoa Garcia-Lliberos, Margaux Legré, David Lobo-Duro, Antonino Maniaci, Thomas Radulesco, Leigh Sowerby, Neil Tan, Manuel Tucciarone, Clair Vandersteen, Valentin Favier and Maxime Fieux
3017	Shoulder Tendinopathy Induced by Statins: A Case Report and Systematic Review by Nicola Manocchio, Carmelo Pirri, Andrea Sorbino, Laura Giordani, Giulia Vita, Concetta Ljoka and Calogero Foti

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252108	Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort by Anna Shcherbina, C. Mikael Mattsson, Daryl Waggott, Heidi Salisbury, Jeffrey W. Christle, Trevor Hastie, Matthew T. Wheeler and Euan A. Ashley
67450	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
61917	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
51878	The Relationship between Autism and Ehlers-Danlos Syndromes/Hypermobility Spectrum Disorders by Emily L. Casanova, Carolina Baeza-Velasco, Caroline B. Buchanan and Manuel F. Casanova
50197	Cerebral Folate Deficiency, Folate Receptor Alpha Autoantibodies and Leucovorin (Folinic Acid) Treatment in Autism Spectrum Disorders: A Systematic Review and Meta-Analysis by Daniel A. Rossignol and Richard E. Frye
48280	Diet, Obesity, and Depression: A Systematic Review by Olivia Patsalos, Johanna Keeler, Ulrike Schmidt, Brenda W. J. H. Penninx, Allan H. Young and Hubertus Himmerich
46257	ADHD: Reviewing the Causes and Evaluating Solutions by Luis Núñez-Jaramillo, Andrea Herrera-Solís and Wendy Verónica Herrera-Morales
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40646	Health 2050: The Realization of Personalized Medicine through Crowdsourcing, the Quantified Self, and the Participatory Biocitizen by Melanie Swan
38233	Fenugreek and Its Effects on Muscle Performance: A Systematic Review by Waleed I. Albaker

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19016	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
7570	Vasopressin in Sepsis and Other Shock States: State of the Art by Raquel García-Álvarez and Rafael Arboleda-Salazar
7177	Ethical Conundrums in the Application of Artificial Intelligence (AI) in Healthcare—A Scoping Review of Reviews by Sreenidhi Prakash, Jyotsna Needamangalam Balaji, Ashish Joshi and Krishna Mohan Surapaneni
6515	A Pathophysiological Approach to Spontaneous Orbital Meningoceles: Case Report and Systematic Review by Piergiorgio Gaudioso, Elia Biancoli, Veronica Battistuzzi, Stefano Concheri, Tommaso Saccardo, Sebastiano Franchella, Giacomo Contro, Stefano Taboni, Elisabetta Zanoletti, Francesco Causin, Lorena Nico, Joseph Domenico Gabrieli, Roberto Maroldi, Piero Nicolai and Marco Ferrari
5519	Management of Hyponatremia in Heart Failure: Practical Considerations by Victoriţa Şorodoc, Andreea Asaftei, Gabriela Puha, Alexandr Ceasovschih, Cătălina Lionte, Oana Sîrbu, Cristina Bologa, Raluca Ecaterina Haliga, Mihai Constantin, Adorata Elena Coman, Ovidiu Rusalim Petriș, Alexandra Stoica and Laurenţiu Şorodoc
5009	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
3669	Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies by Fernando Ramasco, Jesús Nieves-Alonso, Esther García-Villabona, Carmen Vallejo, Eduardo Kattan and Rosa Méndez
3563	Type 1 Diabetes Mellitus and Autoimmune Diseases: A Critical Review of the Association and the Application of Personalized Medicine by Mihaela Simona Popoviciu, Nirja Kaka, Yashendra Sethi, Neil Patel, Hitesh Chopra and Simona Cavalu
3553	From Sweet to Sour: SGLT-2-Inhibitor-Induced Euglycemic Diabetic Ketoacidosis by Andrijana Koceva and Nika Aleksandra Kravos Tramšek
3507	Predicting the Onset of Diabetes with Machine Learning Methods by Chun-Yang Chou, Ding-Yang Hsu and Chun-Hung Chou

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6515	A Pathophysiological Approach to Spontaneous Orbital Meningoceles: Case Report and Systematic Review by Piergiorgio Gaudioso, Elia Biancoli, Veronica Battistuzzi, Stefano Concheri, Tommaso Saccardo, Sebastiano Franchella, Giacomo Contro, Stefano Taboni, Elisabetta Zanoletti, Francesco Causin, Lorena Nico, Joseph Domenico Gabrieli, Roberto Maroldi, Piero Nicolai and Marco Ferrari
5009	Reversal of Autism Symptoms among Dizygotic Twins through a Personalized Lifestyle and Environmental Modification Approach: A Case Report and Review of the Literature by Christopher R. D’Adamo, Josephine L. Nelson, Sara N. Miller, Maria Rickert Hong, Elizabeth Lambert and Heather Tallman Ruhm
3669	Challenges in Septic Shock: From New Hemodynamics to Blood Purification Therapies by Fernando Ramasco, Jesús Nieves-Alonso, Esther García-Villabona, Carmen Vallejo, Eduardo Kattan and Rosa Méndez
3553	From Sweet to Sour: SGLT-2-Inhibitor-Induced Euglycemic Diabetic Ketoacidosis by Andrijana Koceva and Nika Aleksandra Kravos Tramšek
3218	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
2976	Point of Care Ultrasound (POCUS) in the Management of Heart Failure: A Narrative Review by Nicki Naddaf, Neda Dianati Maleki, Marc E. Goldschmidt and Andreas P. Kalogeropoulos
2657	Breaking Barriers—The Intersection of AI and Assistive Technology in Autism Care: A Narrative Review by Antonio Iannone and Daniele Giansanti
2467	Applications of Artificial Intelligence in the Neuropsychological Assessment of Dementia: A Systematic Review by Isabella Veneziani, Angela Marra, Caterina Formica, Alessandro Grimaldi, Silvia Marino, Angelo Quartarone and Giuseppa Maresca
2227	Patient-Generated Health Data (PGHD): Understanding, Requirements, Challenges, and Existing Techniques for Data Security and Privacy by Pankaj Khatiwada, Bian Yang, Jia-Chun Lin and Bernd Blobel
2211	The Promise of Explainable AI in Digital Health for Precision Medicine: A Systematic Review by Ben Allen

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3218	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
1609	Digital Twins’ Advancements and Applications in Healthcare, Towards Precision Medicine by Konstantinos Papachristou, Paraskevi F. Katsakiori, Panagiotis Papadimitroulas, Lidia Strigari and George C. Kagadis
1361	Advances in mRNA LNP-Based Cancer Vaccines: Mechanisms, Formulation Aspects, Challenges, and Future Directions by Eslam Ramadan, Ali Ahmed and Youssef Wahib Naguib
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1036	Genetic and Regulatory Mechanisms of Comorbidity of Anxiety, Depression and ADHD: A GWAS Meta-Meta-Analysis Through the Lens of a System Biological and Pharmacogenomic Perspective in 18.5 M Subjects by Kai-Uwe Lewandrowski, Kenneth Blum, Alireza Sharafshah, Kyriaki Z. Thanos, Panayotis K. Thanos, Richa Zirath, Albert Pinhasov, Abdalla Bowirrat, Nicole Jafari, Foojan Zeine, Milan Makale, Colin Hanna, David Baron, Igor Elman, Edward J. Modestino, Rajendra D. Badgaiyan, Keerthy Sunder, Kevin T. Murphy, Ashim Gupta, Alex P. L. Lewandrowski, Rossano Kepler Alvim Fiorelli and Sergio Schmidt Show full author list Hide full author list
955	Opportunities and Challenges of Chatbots in Ophthalmology: A Narrative Review by Mehmet Cem Sabaner, Rodrigo Anguita, Fares Antaki, Michael Balas, Lars Christian Boberg-Ans, Lorenzo Ferro Desideri, Jakob Grauslund, Michael Stormly Hansen, Oliver Niels Klefter, Ivan Potapenko, Marie Louise Roed Rasmussen and Yousif Subhi
950	Considering Biomarkers of Neurodegeneration in Alzheimer’s Disease: The Potential of Circulating Cell-Free DNA in Precision Neurology by Chad A. Pollard, Erin R. Saito, Jeffrey M. Burns, Jonathon T. Hill and Timothy G. Jenkins
879	Corticosteroids in Pediatric Septic Shock: A Narrative Review by Immacolata Rulli, Angelo Mattia Carcione, Federica D’Amico, Giuseppa Quartarone, Roberto Chimenz and Eloisa Gitto

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3218	Point of View: A Holistic Four-Interface Conceptual Model for Personalizing Shock Resuscitation by Philippe Rola, Eduardo Kattan, Matthew T. Siuba, Korbin Haycock, Sara Crager, Rory Spiegel, Max Hockstein, Vimal Bhardwaj, Ashley Miller, Jon-Emile Kenny, Gustavo A. Ospina-Tascón and Glenn Hernandez
557	One-Stop Mitral Valve Transcatheter Edge-to-Edge Repair and Left Atrial Appendage Occlusion in Patients with Atrial Fibrillation and Mitral Regurgitation: A Systematic Review and Meta-Analysis by Konstantinos Pamporis, Dimitrios Tsiachris, Konstantinos Grigoriou, Paschalis Karakasis, Ioannis Doundoulakis, Panagiotis Theofilis, Panagiotis Kouvatsos, Athanasios Saplaouras, Athanasios Kordalis, Aikaterini-Eleftheria Karanikola, Panagiotis Antonios Goutis and Konstantinos Tsioufis
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493	Right Ventricular Strain by Echocardiography: Current Clinical Applications and Future Directions for Mechanics Assessment of the Forgotten Ventricle by Mahmoud Abdelnabi, Ramzi Ibrahim, Hoang Nhat Pham, Bobbi Jo Heon, George Bcharah, Girish Pathangey, Milagros Pereyra Pietri, Juan M. Farina, Ian C. Chang, Reza Arsanjani and Chadi Ayoub
484	Impact of Pharmacological Treatments on Rheumatoid Arthritis-Associated Diffuse Interstitial Lung Disease: A Systematic Review and Meta-Analysis by Ariam A. Muarif, Rana Algahtani, Lujain H. Alghamdi, Sarah S. Alghamdi, Lama Al Nemer, Reman Alsaqrah, Yazeed Alsulami, Maha Alsharif, Dana Alznbagi, Lena Aljehani, Ziyad Alsaeedi, Sultan Alghamdi, Taif A. Sayel, Basma Al Ghamdi and Ali Al Bshabshe
461	The Accuracy of ChatGPT-4o in Interpreting Chest and Abdominal X-Ray Images by Pietro G. Lacaita, Malik Galijasevic, Michael Swoboda, Leonhard Gruber, Yannick Scharll, Fabian Barbieri, Gerlig Widmann and Gudrun M. Feuchtner
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437	Interstitial Lung Diseases and Lung Cancer: A Review on Similarities, Common Pathogenesis and Therapeutic Approach by Gioele Castelli, Elisabetta Cocconcelli, Giuliana Grimaudo, Irene Di Leo, Serena Bellani, Giordano Fiorentù, Giacomo Giulianelli, Nicol Bernardinello, Elisabetta Balestro and Paolo Spagnolo
434	Artificial Intelligence in the Assessment and Grading of Acne Vulgaris: A Systematic Review by Daniele Omar Traini, Gerardo Palmisano, Cristina Guerriero and Ketty Peris
433	Computational and Imaging Approaches for Precision Characterization of Bone, Cartilage, and Synovial Biomolecules by Rahul Kumar, Kyle Sporn, Vibhav Prabhakar, Ahab Alnemri, Akshay Khanna, Phani Paladugu, Chirag Gowda, Louis Clarkson, Nasif Zaman and Alireza Tavakkoli

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19016	A Review of the Role of Artificial Intelligence in Healthcare by Ahmed Al Kuwaiti, Khalid Nazer, Abdullah Al-Reedy, Shaher Al-Shehri, Afnan Al-Muhanna, Arun Vijay Subbarayalu, Dhoha Al Muhanna and Fahad A. Al-Muhanna
17177	Accuracy in Wrist-Worn, Sensor-Based Measurements of Heart Rate and Energy Expenditure in a Diverse Cohort by Anna Shcherbina, C. Mikael Mattsson, Daryl Waggott, Heidi Salisbury, Jeffrey W. Christle, Trevor Hastie, Matthew T. Wheeler and Euan A. Ashley
16553	Global Challenges to Public Health Care Systems during the COVID-19 Pandemic: A Review of Pandemic Measures and Problems by Roxana Filip, Roxana Gheorghita Puscaselu, Liliana Anchidin-Norocel, Mihai Dimian and Wesley K. Savage
15952	Applications of Machine Learning Predictive Models in the Chronic Disease Diagnosis by Gopi Battineni, Getu Gamo Sagaro, Nalini Chinatalapudi and Francesco Amenta
14896	Health 2050: The Realization of Personalized Medicine through Crowdsourcing, the Quantified Self, and the Participatory Biocitizen by Melanie Swan
14018	The Impact of Marijuana on Antidepressant Treatment in Adolescents: Clinical and Pharmacologic Considerations by Samuel E. Vaughn, Jeffrey R. Strawn, Ethan A. Poweleit, Mayur Sarangdhar and Laura B. Ramsey
11556	Digital Twins: From Personalised Medicine to Precision Public Health by Maged N. Kamel Boulos and Peng Zhang
11269	Breast Cancer Treatments: Updates and New Challenges by Anna Burguin, Caroline Diorio and Francine Durocher
10343	Infectious Disease Management through Point-of-Care Personalized Medicine Molecular Diagnostic Technologies by Luc Bissonnette and Michel G. Bergeron
10146	Aligning the Aligners: Comparison of RNA Sequencing Data Alignment and Gene Expression Quantification Tools for Clinical Breast Cancer Research by Isaac D. Raplee, Alexei V. Evsikov and Caralina Marín de Evsikova

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