Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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New Insight into Aging and Geriatric Syndromes: Clinical Updates and Perspectives submission deadline 10 Jul 2026 | 9 articles | Viewed by 33052 | Submission Open
Keywords: gerodontology; dementia; mild cognitive impairment (MCI); frontotemporal dementia; frailty; late-life depression; sarcopenia; sensorial impairments; multimorbidity; oral frailty; longevity; biological aging
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advances in Precision Medicine for Gastrointestinal Cancers
edited by
submission deadline 10 Jul 2026 | Viewed by 291 | Submission Open
Keywords: gastrointestinal cancer; precision medicine; personalized medicine; diagnostic imaging; genomic testing; proteomics; molecular targeted drug; immune checkpoint inhibitors; artificial intelligence
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Combating Antimicrobial Resistance: Translational Science to Clinical Practice
edited by Giovanni Gherardi and Roberta Creti
submission deadline 15 Jul 2026 | Viewed by 332 | Submission Open
Keywords: antimicrobial resistance (AMR); One Health approach; new antibacterial strategies; antimicrobial and diagnostic stewardship
(This special issue belongs to the Section Omics/Informatics)
AI-BioEng: Smart Diagnostics and Therapeutic Innovations in Biomedical Engineering
edited by
submission deadline 15 Jul 2026 | Viewed by 232 | Submission Open
Keywords: AI-based diagnostics; predictive disease modeling; intelligent monitoring systems; wearable and implantable devices; real-time therapeutic feedback; predictive modeling
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Treatment of Neurological Diseases submission deadline 20 Jul 2026 | 2 articles | Viewed by 10634 | Submission Open
Keywords: neurological diseases; neurodegenerative diseases; Alzheimer’s disease; Parkinson’s disease; neurodegeneration; dementia; epilepsy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Orthopedic Diseases: Advances in Limb Reconstruction
edited by Taylor J. Reif and Jason Shih Hoellwarth
submission deadline 20 Jul 2026 | 3 articles | Viewed by 4432 | Submission Open
Keywords: limb lengthening; limb deformity; malunion; nonunion; limb salvage; amputation reconstruction; osseointegration; osteomyelitis; patient-specific surgery; patient-specific instrumentation
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies
edited by Eyal Yaacobi
submission deadline 20 Jul 2026 | 1 articles | Viewed by 2796 | Submission Open
Keywords: orthopedic treatment; surgical technics; limb salvage; rehabilitation
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Approaches in Neurosurgery
edited by Alessandro Boaro and Marco Mammi
submission deadline 25 Jul 2026 | 3 articles | Viewed by 9661 | Submission Open
Keywords: neurosurgery; neuronavigation; neuro-imaging; clinical outcomes; machine learning
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Inborn Errors of Metabolism: From Pathomechanisms to Treatment submission deadline 25 Jul 2026 | 2 articles | Viewed by 4811 | Submission Open
Keywords: inherited metabolic disorders; pathway signaling; organelle interactions; immunomodulators; antioxidants; gene therapy
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Pathological Diagnosis submission deadline 25 Jul 2026 | 1 articles | Viewed by 1740 | Submission Open
Keywords: personalized medicine; pathology; pathological; trauma; toxicology; informed consent
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Diagnosis and Management of Stroke
edited by Rubens José Gagliardi
submission deadline 25 Jul 2026 | 1 articles | Viewed by 1285 | Submission Open
Keywords: stroke; cerebrovascular disease; carotid disease; epidemiology
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
From Acute Injury to Personalized Prevention—Developing Modern Strategies submission deadline 25 Jul 2026 | Viewed by 424 | Submission Open
Keywords: orthopedics; acute injury; personalized prevention; innovative methodologies; musculoskeletal disorders; musculoskeletal injury; conservative therapy; functional testing; intervention
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Molecular Pathology of Digestive Oncology
edited by
submission deadline 25 Jul 2026 | Viewed by 191 | Submission Open
Keywords: molecular biomarkers; genetic and epigenetic alterations; tumor microenvironment; gut microbiome; carcinogenesis; early detection
(This special issue belongs to the Section Molecular Targeted Therapy)
Novel Challenges and Advances in Orthopaedic and Trauma Surgery submission deadline 30 Jul 2026 | 4 articles | Viewed by 17315 | Submission Open
Keywords: orthopaedic surgery; traumatology; musculoskeletal disorders; innovation in orthopaedics; individualised treatment; post-operative rehabilitation; clinical research
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Cardiothoracic Surgery: Challenges and Future Perspectives
edited by Thomas Theologou
submission deadline 30 Jul 2026 | 1 articles | Viewed by 1509 | Submission Open
Keywords: cardiothoracic surgery; minimally invasive surgery; robotic surgery; heart transplantation; lung transplantation; thoracic oncology; perioperative care; artificial intelligence in surgery; surgical innovation; postoperative complications; personalized medicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Orthopaedics, 2nd Edition submission deadline 31 Jul 2026 | 7 articles | Viewed by 19916 | Submission Open
Keywords: outcomes; orthopedic surgery; traumatology; radiography; complication
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Treatment for Heart Failure
edited by Shunsuke Kiuchi
submission deadline 31 Jul 2026 | 5 articles | Viewed by 11347 | Submission Open
Keywords: hypertension; heart failure; prevention; left ventricular contractility; cardiovascular outcomes; cardiology
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advances in Ischemic Stroke Management: Toward Precision Medicine
edited by Bruno Kusznir Vitturi
submission deadline 31 Jul 2026 | 1 articles | Viewed by 1851 | Submission Open
Keywords: cerebrovascular diseases; ischemic stroke; brain hemorrhage; secondary prevention; thrombolysis; endovascular treatment
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Kidney Transplantation
edited by Jon Von Visger
submission deadline 31 Jul 2026 | Viewed by 282 | Submission Open
Keywords: kidney transplantation; personalized medicine; renal disease; nephrology; graft survival; immunosuppressive therapy; recurrent disease; patient survival; access to transplant
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Gastric Cancer Treatment: Recent Progress and Future Perspectives
edited by Gagandeep Brar
submission deadline 10 Aug 2026 | Viewed by 226 | Submission Open
Keywords: gastric cancer; biomarkers; targeted therapy; personalized medicine
(This special issue belongs to the Section Precision Oncology)
Recent Innovations and Artificial Intelligence in Interventional Radiology: A Step Towards Personalized Medicine
edited by , Giuseppe Pellegrino and Salvatore Alessio Angileri
submission deadline 15 Aug 2026 | 3 articles | Viewed by 6741 | Submission Open
Keywords: interventional radiology; artificial intelligence; augmented reality
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Ehealth, Telemedicine, and AI in the Precision Medicine Era
edited by
submission deadline 20 Aug 2026 | 5 articles | Viewed by 31107 | Submission Open
Keywords: digital health; artificial intelligence; telemedicine; telerehabilitation; E-health; precision medicine; remote monitoring; wearable devices; mobile health (mHealth); virtual health; health informatics; machine learning; predictive analytics; personalized medicine; health technology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Clinical Research of Minimally Invasive Spine Surgery
edited by and Bertrand Debono
submission deadline 20 Aug 2026 | 2 articles | Viewed by 5383 | Submission Open
Keywords: minimally invasive spine surgery; MISS; surgical techniques; patient outcomes; clinical research; technological advancements; robotics; navigation systems; patient safety; quality of life
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Mechanisms of Airway Inflammation in Asthma
edited by Kathleen Haley
submission deadline 20 Aug 2026 | 4 articles | Viewed by 3960 | Submission Open
Keywords: asthma; inflammation in asthma; targeted therapies; acute respiratory distress syndrome; chronic lung diseases; critical care
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Therapeutic Strategies in Gastrointestinal Surgery
edited by Francesco Santullo
submission deadline 20 Aug 2026 | 1 articles | Viewed by 2754 | Submission Open
Keywords: surgical oncology; cytoreductive surgery; laparoscopic surgery; colorectal surgery; gastric cancer; hipec; pipac; peritoneal metastases
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Interventional Cardiology: Latest Technology, Progress and Challenge
edited by Grzegorz Sobieszek and Maksymilian P. Opolski
submission deadline 25 Aug 2026 | 2 articles | Viewed by 6251 | Submission Open
Keywords: interventional cardiology; chronic total occlusions (CTO); complex and high-risk coronary interventions (CHIP); intravascular lithotripsy (IVL); structural heart interventions; heart failure interventional treatment; electrotherapy; right- and left-ventricle hemodynamic support; left-ventricle assist device (LVAD)
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
State of the Art in Cardiac Imaging
edited by
submission deadline 25 Aug 2026 | 2 articles | Viewed by 6111 | Submission Open
Keywords: cardiology; imaging; scintigraphy; SPECT; PET; computed tomography; magnetic resonance; echocardiography; heart failure; coronary artery disease
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Gestational Diabetes: Challenges and Cutting-Edge Research submission deadline 25 Aug 2026 | 2 articles | Viewed by 2884 | Submission Open
Keywords: gestational diabetes; continuous glucose monitor; fetal health; pregnancy; macrosomia; personalized management
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Management of Heart Failure: From Biomarkers to Clinical Practice submission deadline 25 Aug 2026 | 1 articles | Viewed by 2254 | Submission Open
Keywords: heart failure (HF); cardiac biomarkers; guideline-directed medical therapy (GDMT); risk stratification; HF phenotypes; HF management; digital health
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Precision Pathology: Bridging Digital Innovation and Molecular Diagnostics submission deadline 25 Aug 2026 | 1 articles | Viewed by 1640 | Submission Open
Keywords: precision pathology; digital pathology; molecular diagnostics; artificial intelligence in pathology; computational pathology; multi-omics integration; biomarker discovery; translational medicine
(This special issue belongs to the Section Omics/Informatics)
Advancing Tailored Diagnostics and Therapeutics in Autoimmune and Rheumatic Diseases via Integration of Traditional Approaches and AI Technologies
edited by Edda Russo and Francesca Romano
submission deadline 25 Aug 2026 | 1 articles | Viewed by 1195 | Submission Open
Keywords: autoimmune diseases; personalized therapeutics; biomarker profiling; artificial intelligence (AI); targeted immunotherapy
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Pediatric Surgery: Updates and Perspectives submission deadline 25 Aug 2026 | Viewed by 256 | Submission Open
Keywords: personalized medicine; pediatric surgery; genomics; surgical oncology; inflammatory bowel disease; obesity; metabolic surgery; Hirschsprung's disease; artificial intelligence; machine learning
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Urological Diseases: Updates and Challenges on Personalized Diagnosis, Treatment, and Management
edited by Michael Chrisofos
submission deadline 27 Aug 2026 | 2 articles | Viewed by 3278 | Submission Open
Keywords: minimally invasive surgeries; robotic surgery; laparoscopic surgery; personalized medicine; diagnostic modalities; precision diagnosis; incontinence; endourology; andrology; urologic surgery; urological diseases; prostate cancer
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Anesthesia and Intensive Care
edited by Marc Olivier Fischer
submission deadline 27 Aug 2026 | 1 articles | Viewed by 1384 | Submission Open
Keywords: anaesthesia; critical care; personalized medicine; preoperative risk stratification; close loop anaesthesia; mechanical ventilation; individualized sedation; postoperative outcome; postoperative trajectories
(This special issue belongs to the Section Personalized Medical Care)
Biomedical Tools in Diagnosis and Personalized Therapy of Cardiovascular Disease
edited by Nikolaos Koumallos and Konstantinos A. Aznaouridis
submission deadline 30 Aug 2026 | 2 articles | Viewed by 6385 | Submission Open
Keywords: cardiovascular disease; diagnosis; personalized therapy; biomedical tools; cardiovascular imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
State of the Art in Pathogenesis and Targeted Therapy in Chronic Obstructive Pulmonary Disease
edited by Emanuela Tudorache
submission deadline 30 Aug 2026 | 1 articles | Viewed by 1143 | Submission Open
Keywords: COPD; effective treatments; molecular; genetic; inflammation; biomarkers for diagnosis and prognosis; personalized medicine; novel drug delivery systems; patient outcomes; clinical practice
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Management of Inflammatory Bowel Diseases
edited by
submission deadline 30 Aug 2026 | 1 articles | Viewed by 533 | Submission Open
Keywords: inflammatory bowel disease; precision medicine; personalized management; biomarkers; intestinal ultrasound; advanced imaging; disease monitoring
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Towards Precision Anesthesia and Pain Management
edited by , Joseph V. Pergolizzi and Filomena Puntillo
submission deadline 31 Aug 2026 | 5 articles | Viewed by 23052 | Submission Open
Keywords: precision medicine; anesthesia; pain medicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
United Airway Disease: Current Perspectives submission deadline 31 Aug 2026 | 3 articles | Viewed by 16416 | Submission Open
Keywords: chronic rhinosinusitis; asthma; personalized medicine; type-2 inflammation; united airway; obstructive sleep apnoea; monoclonal antibodies; endotype; rhinology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Clinical Advances in Traumatic Brain Injury and Concussion
edited by Spencer W. Liebel
submission deadline 31 Aug 2026 | 1 articles | Viewed by 13116 | Submission Open
Keywords: traumatic brain injury; concussion; personalized medicine; neuroimaging; cognitive functioning; depression; connectomics; brain injury treatment
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Clinical Advances in Diagnosis and Personalized Treatments of Chronic Kidney Diseases submission deadline 31 Aug 2026 | 5 articles | Viewed by 9889 | Submission Open
Keywords: biomarkers for early diagnosis; genetic testing; precision medicine approaches; novel therapies; telemedicine and remote monitoring; nutritional interventions; regenerative medicine
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Advances in Prenatal Diagnosis and Maternal Fetal Medicine submission deadline 31 Aug 2026 | 5 articles | Viewed by 9292 | Submission Open
Keywords: prenatal diagnosis; maternal–fetal medicine; fetal anomalies; genetic screening; fetal imaging; non-invasive prenatal testing (NIPT); obstetric care; perinatal outcomes; diagnostic technologies; artificial intelligence
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Integrating Mathematical Modeling and Data Analysis in Personalized Medical Research submission deadline 31 Aug 2026 | 4 articles | Viewed by 8237 | Submission Open
Keywords: personalized medicine; health informatics; mathematical modeling; data analysis; bioinformatics; artificial intelligence; machine learning
(This special issue belongs to the Section Omics/Informatics)
Updates on Heart Valve Diseases: Personalized Treatment and Management
edited by Chiara Tessari
submission deadline 31 Aug 2026 | 4 articles | Viewed by 8085 | Submission Open
Keywords: heart valve disease; congenital heart valve disease; transcatheter valve implantation/replacement; surgical technique; device technology; tissue engineering; structural valve deterioration; device failure/success
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Personalized Medicine in Infectious Diseases submission deadline 31 Aug 2026 | 1 articles | Viewed by 6634 | Submission Open
Keywords: infectious diseases; genetic predisposition; post-acute infection syndromes; long-COVID; response, potential adverse events, and duration of protection of vaccines; response to therapy and development of resistance; personalized medicine; precision diagnostics; treatment strategies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Novel Applications of Artificial Intelligence in Personalized Medicine
edited by Aikaterini Sakagianni
submission deadline 31 Aug 2026 | 3 articles | Viewed by 5345 | Submission Open
Keywords: artificial intelligence ; personalized medicine ; predictive modeling ; genomics ; proteomics ; AI-driven diagnostics ; patient-specific treatment ; drug discovery ; healthcare innovation ; clinical applications of AI
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in the ICU—2nd Edition submission deadline 31 Aug 2026 | 2 articles | Viewed by 4084 | Submission Open
Keywords: ARDS; mechanical ventilation; respiratory mechanics; monitoring; ultrasonography; respiratory muscles; diaphragm; cardiomyopathy; arrhythmias; sepsis; blood stream infections; antimicrobial resistance; ventilator-associated pneumonia; neuromonitoring; MODS; COVID-19
(This special issue belongs to the Section Personalized Medical Care)
Personalized Medicine in Gynecological Oncology: Update and Challenge
edited by
submission deadline 31 Aug 2026 | 1 articles | Viewed by 1283 | Submission Open
Keywords: gynecologic oncology; personalized medicine; imaging and biomarkers; fertility-sparing surgery
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
Cell-Free Nucleic Acids as Precision Biomarkers for Therapeutic Decision-Making Across Diseases
edited by and Francis Barany
submission deadline 31 Aug 2026 | 1 articles | Viewed by 585 | Submission Open
Keywords: liquid biopsy; cell-free nucleic acids; cancer; therapeutic decision; cell-free DNA
(This special issue belongs to the Section Disease Biomarkers)
New Insights into the Diagnosis and Treatment of Gastroenterological Diseases
edited by and Harleen Chela
submission deadline 31 Aug 2026 | Viewed by 297 | Submission Open
Keywords: gastroenterology; precision medicine; multi-omics integration; pharmacogenomics; liquid biopsy; gastrointestinal biomarkers; inflammatory bowel disease (IBD); individualized treatment strategies
(This special issue belongs to the Section Personalized Therapy in Clinical Medicine)
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