Special Issues

Journal of Personalized Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Update on Robotic Gastrointestinal Surgery, 2nd Edition
edited by
submission deadline 10 Aug 2025 | 4 articles | Viewed by 12571 | Submission Open
Keywords: robotic; minimally invasive surgery; esophageal; gastric; colorectal; pancreatic; hepatic
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Treatment for Heart Failure
edited by Shunsuke Kiuchi
submission deadline 10 Aug 2025 | 2 articles | Viewed by 2018 | Submission Open
Keywords: hypertension; heart failure; prevention; left ventricular contractility; cardiovascular outcomes; cardiology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Cardiothoracic Surgery
edited by Castigliano Murthy Bhamidipati
submission deadline 15 Aug 2025 | 4 articles | Viewed by 3301 | Submission Open
Keywords: adult congenital heart disease; electrophysiology; complex aortic surgery; endocarditis; coronary artery disease; valvular heart disease
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Current Updates on Vascular Surgery in Personalized Medicine
edited by
submission deadline 15 Aug 2025 | Viewed by 141 | Submission Open
Keywords: carotid atherosclerosis; hematologic and radiologic biomarkers; carotid disease; plaque characterization; risk stratification
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Current Trends and Future Challenges in Assisted Reproduction
edited by
submission deadline 20 Aug 2025 | 8 articles | Viewed by 21821 | Submission Open
Keywords: infertility; fertility preservation; reproductive medicine; reproductive genetics; assisted reproduction; gynecology; andrology; embryology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Multiple Pregnancies: Optimal Follow-Up, Early Detection and Management of Complications, and Appropriate Mode and Time of Delivery submission deadline 20 Aug 2025 | 1 articles | Viewed by 1868 | Submission Open
Keywords: multiple pregnancy; twin pregnancy; triplet pregnancy; monochorionic pregnancy; monochorionic twins; monochorionic monoamniotic pregnancy; monochorionic diamniotic pregnancy; dichorionic diamniotic pregnancy; quadruplet pregnancy; chorionicity; amnionicity; conjoined twins; in vitro fertilization; assisted reproductive techniques; advanced maternal age; natural conception; pregnancy dating; aneuploidy screening; twin-to-twin transfusion syndrome (TTTS); fetal growth restriction (FGR); selective fetal growth restriction (sFGR); twin anemia-polycythemia sequence (TAPS); twin reversed arterial perfusion sequence (TRAP); fetoscopy; laser ablation; fetal laser therapy; laser therapy; bipolar cord coagulation; radiofrequency ablation; selective feticide; elective fetal reduction; elective termination of pregnancy; discordant fetal anomaly; structural abnormalities; single intrauterine fetal demise; cerclage; threatened preterm labor; preterm birth; preeclampsia; gestational hypertension; gestational diabetes; fetal ultrasound; fetal therapy; delivery; vaginal delivery; operative vaginal delivery; cesarean section; adverse perinatal outcomes
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Inborn Errors of Metabolism: From Pathomechanisms to Treatment submission deadline 20 Aug 2025 | 1 articles | Viewed by 1084 | Submission Open
Keywords: inherited metabolic disorders; pathway signaling; organelle interactions; immunomodulators; antioxidants; gene therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Prevention and Personalized Treatment of Substance Use Disorders submission deadline 22 Aug 2025 | Viewed by 228 | Submission Open
Keywords: substance use disorder; substance dependency; biomarkers; artificial intelligence; machine learning; precision phenotyping; genomics; clinical trial
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Coronary Syndromes: Clinical Research and Personalized Medicine
edited by Miguel Nobre Menezes and Daniel Caldeira
submission deadline 25 Aug 2025 | 1 articles | Viewed by 3675 | Submission Open
Keywords: coronary artery disease; percutaneous coronary intervention; coronary artery bypass surgery; antiplatelet therapy; new and upcoming drugs for dyslipidemia; medical therapy for chronic and acute coronary syndromes; invasive and non-invasive diagnostic modalities; non-epicardial coronary artery disease; coronary artery disease in special populations (elderly; cancer; etc.); cardiovascular risk factors
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Research of Minimally Invasive Spine Surgery
edited by and Bertrand Debono
submission deadline 25 Aug 2025 | 2 articles | Viewed by 3190 | Submission Open
Keywords: minimally invasive spine surgery; MISS; surgical techniques; patient outcomes; clinical research; technological advancements; robotics; navigation systems; patient safety; quality of life
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Therapeutic Strategies in Gastrointestinal Surgery
edited by Francesco Santullo
submission deadline 25 Aug 2025 | 1 articles | Viewed by 567 | Submission Open
Keywords: surgical oncology; cytoreductive surgery; laparoscopic surgery; colorectal surgery; gastric cancer; hipec; pipac; peritoneal metastases
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Diagnosis and Management of Stroke
edited by Rubens José Gagliardi
submission deadline 25 Aug 2025 | Viewed by 181 | Submission Open
Keywords: stroke; cerebrovascular disease; carotid disease; epidemiology
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Therapeutic Approaches to Asthma in Clinical Medicine
edited by Howraman Meteran
submission deadline 25 Aug 2025 | Viewed by 160 | Submission Open
Keywords: asthma management; novel asthma therapies; biologic treatments for asthma; personalized medicine in asthma; monoclonal antibodies; severe asthma; precision medicine; immune-modulating therapies; gene therapy in asthma; innovative drug delivery systems; microbiome and asthma; inflammation control in asthma; asthma biomarkers; airway remodeling; corticosteroid alternatives
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Orthopaedics, 2nd Edition submission deadline 30 Aug 2025 | 7 articles | Viewed by 13384 | Submission Open
Keywords: outcomes; orthopedic surgery; traumatology; radiography; complication
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Advances in Animal Models and Precision Medicine for Cancer Research
edited by and
submission deadline 30 Aug 2025 | 1 articles | Viewed by 1139 | Submission Open
Keywords: animal models; cancer; precision medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Prevention of Gallbladder Cancer submission deadline 31 Aug 2025 | 3 articles | Viewed by 27678 | Submission Open
Keywords: gallbladder cancer; personalized prevention; risk biomarker; primary prevention; secondary prevention/early detection; tertiary prevention/avoidance of gallbladder cancer progression
(This special issue belongs to the Section Mechanisms of Diseases)
New Perspectives, Challenges and Innovations in Modern Personalized Gynaecologic Oncology submission deadline 31 Aug 2025 | 2 articles | Viewed by 10827 | Submission Open
Keywords: gynecologic oncology; surgical oncology; medical oncology; radiation oncology; diagnosis; ethics; palliative treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Progress on Personalized Diagnosis and Treatment of Osteoarthritis submission deadline 31 Aug 2025 | 3 articles | Viewed by 9843 | Submission Open
Keywords: osteoarthritis; knee osteoarthritis; hip osteoarthritis; osteoarthritis diagnosis; osteoarthritis treatment; conservative osteoarthritis treatment; surgical osteoarthritis treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Cold Perspectives: Advancements and Applications of Cryotherapy in Clinical Settings submission deadline 31 Aug 2025 | 4 articles | Viewed by 9534 | Submission Open
Keywords: cryotherapy; local cryotherapy; cryostimulation; partial/local/whole-body cryostimulation; par-tial/local/whole-body cryotherapy; personalized rehabilitation; multidisciplinary rehabilitation; cold therapy; cold exposure; adjuvant therapy
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Novel Challenges and Advances in Orthopaedic and Trauma Surgery submission deadline 31 Aug 2025 | 4 articles | Viewed by 8388 | Submission Open
Keywords: orthopaedic surgery; traumatology; musculoskeletal disorders; innovation in orthopaedics; individualised treatment; post-operative rehabilitation; clinical research
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Medicine in Otolaryngology: Special Topic Otology—2nd Edition submission deadline 31 Aug 2025 | 3 articles | Viewed by 6349 | Submission Open
Keywords: cochlear implants in children; adults; and older adults; active middle-ear implants in children; adults; and the elderly; new indications in otology; active transcutaneous bone conduction implants in children; adults; and the elderly; hearing loss and cholesteatoma; implantable and non-implantable solutions for malformations; age-related hearing loss; single-sided deafness; cochlear implantation; otitis media; tinnitus; quality of life; burden of hearing loss; genetics and epigenetics of hearing loss; robotic surgery; novel biomarkers for the diagnosis and prognosis of hearing loss; novel intra-operative objective measures for hearing implants; alternative treatment options to implantable devices; MRI
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Clinical Advances in Traumatic Brain Injury and Concussion
edited by Spencer W. Liebel
submission deadline 31 Aug 2025 | 1 articles | Viewed by 4814 | Submission Open
Keywords: traumatic brain injury; concussion; personalized medicine; neuroimaging; cognitive functioning; depression; connectomics; brain injury treatment
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Advances in Diagnosis and Personalized Treatments of Chronic Kidney Diseases submission deadline 31 Aug 2025 | 3 articles | Viewed by 3638 | Submission Open
Keywords: biomarkers for early diagnosis; genetic testing; precision medicine approaches; novel therapies; telemedicine and remote monitoring; nutritional interventions; regenerative medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Clinical Updates on Personalized Upper Gastrointestinal Endoscopy submission deadline 31 Aug 2025 | 4 articles | Viewed by 3590 | Submission Open
Keywords: operative endoscopy; post-surgical complications; achalasia; Zenker diverticulum; GERD; gastroparesis
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Biomedical Tools in Diagnosis and Personalized Therapy of Cardiovascular Disease
edited by Nikolaos Koumallos and Konstantinos A. Aznaouridis
submission deadline 31 Aug 2025 | 1 articles | Viewed by 2977 | Submission Open
Keywords: cardiovascular disease; diagnosis; personalized therapy; biomedical tools; cardiovascular imaging
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Pathology and Molecular Diagnostics in the Personalized Treatment of Lung Diseases submission deadline 5 Sep 2025 | 6 articles | Viewed by 8675 | Submission Open
Keywords: lung; tumor; biomarkers; interstitial lung diseases; molecular; infections
(This special issue belongs to the Section Mechanisms of Diseases)
Personalized Medicine in the ICU—2nd Edition submission deadline 10 Sep 2025 | 1 articles | Viewed by 2105 | Submission Open
Keywords: ARDS; mechanical ventilation; respiratory mechanics; monitoring; ultrasonography; respiratory muscles; diaphragm; cardiomyopathy; arrhythmias; sepsis; blood stream infections; antimicrobial resistance; ventilator-associated pneumonia; neuromonitoring; MODS; COVID-19
(This special issue belongs to the Section Personalized Critical Care)
New Advances in Techniques and Personalized Medicine in Cardiology
edited by
submission deadline 10 Sep 2025 | 1 articles | Viewed by 1552 | Submission Open
Keywords: cardiovascular precision therapy; cardiovascular pharmacological therapy; pharmacogenetics; cardio-imaging; epigenetics; personalized medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Colorectal Cancers: Clinical and Therapeutical Updates and Challenges
edited by , and Adrian Constantin
submission deadline 10 Sep 2025 | Viewed by 473 | Submission Open
Keywords: colorectal cancer; clinical research; translational research; cancer biomarker; targeted therapy; medical imaging; colorectal surgery
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Personalized Diagnosis and Treatment of Oligometastatic Disease
edited by
submission deadline 15 Sep 2025 | 1 articles | Viewed by 898 | Submission Open
Keywords: oligometastatic disease; oligorecurrence; oligoprogression; oligoconsolidation; metastasectomy; stereotactic body radiotherapy (SBRT); novel systemic agents; target therapies; chemotherapy; immunotherapy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Trauma Surgery: Strategies, Challenges and Vision of the Future
edited by and Yaniv S. Warschawski
submission deadline 20 Sep 2025 | 2 articles | Viewed by 3962 | Submission Open
Keywords: orthopaedic surgery; fractures; injuries; upper limb; trauma
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances of Precision Medicine in Oncology submission deadline 25 Sep 2025 | 2 articles | Viewed by 7247 | Submission Open
Keywords: precision medicine; personalized cancer care; circulating tumor cells; biomolecules; liquid biopsies; omics technologies; biomarkers
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Cutting-Edge Diagnostics: The Impact of Imaging on Precision Medicine
edited by
submission deadline 25 Sep 2025 | 2 articles | Viewed by 4166 | Submission Open
Keywords: advanced imaging techniques; AI-enhanced imaging; molecular imaging; imaging biomarkers; precision medicine; personalized diagnostics; early disease detection; imaging data integration; genomics and imaging; imaging-guided interventions; clinical imaging applications; comparative imaging effectiveness; innovative imaging technologies; medical imaging advances; diagnostic accuracy; patient-specific imaging; functional imaging; quantitative imaging; radiomics; theranostics
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
The Applications of Non-Invasive Brain Stimulation in Neuropsychiatric Research and Treatment submission deadline 25 Sep 2025 | 1 articles | Viewed by 2125 | Submission Open
Keywords: neuroscience; non-invasive brain stimulation; rehabilitation; neuropsychiatric; neurophysiology; neuropsychology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Current Updates on Arrhythmia and Cardiac Electrophysiology submission deadline 25 Sep 2025 | 1 articles | Viewed by 2007 | Submission Open
Keywords: ablation energy mode; conduction system pacing; pulsed field ablation; leadless pacing; resynchronization; myocardial work; atrial fibrillation
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Personalized Medicine in Pathological Diagnosis submission deadline 25 Sep 2025 | 1 articles | Viewed by 675 | Submission Open
Keywords: personalized medicine; pathology; pathological; trauma; toxicology; informed consent
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Orthopedic Diseases: Advances in Limb Reconstruction
edited by Taylor J. Reif and Jason Shih Hoellwarth
submission deadline 25 Sep 2025 | 1 articles | Viewed by 583 | Submission Open
Keywords: limb lengthening; limb deformity; malunion; nonunion; limb salvage; amputation reconstruction; osseointegration; osteomyelitis; patient-specific surgery; patient-specific instrumentation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Interventional Radiology in Oncology
edited by
submission deadline 25 Sep 2025 | Viewed by 383 | Submission Open
Keywords: artificial intelligence; oncological imaging; hybrid imaging; endovascular radiology; percutaneous procedures; radiomics; MRI; CT; PET/CT; photon-counting CT; cone-beam CT
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
Pathological Mechanism of Breast Cancer
edited by
submission deadline 25 Sep 2025 | Viewed by 364 | Submission Open
Keywords: breast cancer; metastatic breast cancer; biomarkers; molecular profiling; immune landscape; genomics; personalized treatment; targeted therapy
(This special issue belongs to the Section Mechanisms of Diseases)
Neuroimaging Biomarkers for Precision Medicine in Neuropsychiatry: A Multidisciplinary Update
edited by
submission deadline 25 Sep 2025 | Viewed by 180 | Submission Open
Keywords: neuroimaging; neuropsychiatry; psychiatry; psychology; neuroscience; biomarkers; precision medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Precision Medicine in Neuro-Imaging: Advances and Challenges
edited by Onur Tanglay
submission deadline 25 Sep 2025 | Viewed by 125 | Submission Open
Keywords: neuroimaging; precision medicine; biomarkers; brain health; neurotechnology
(This special issue belongs to the Section Methodology, Drug and Device Discovery)
How to Undertake Personalized Assessments and Cures for Pain
edited by Barbara Rocca and
submission deadline 30 Sep 2025 | 6 articles | Viewed by 13270 | Submission Open
Keywords: pain; suffering; personalization; evaluation; treatment; outcome; medicine; surgery; rehabilitation; psychology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Head and Neck Oncologic Surgery: Clinical Updates and New Perspectives in Precision Medicine Era
edited by Filippo Carta and Roberto Puxeddu
submission deadline 30 Sep 2025 | 3 articles | Viewed by 7736 | Submission Open
Keywords: head and neck cancer; squamous cell carcinoma; free flap; microsurgery; oral cancer; laryngeal cancer; pharyngeal cancer; skin cancer; salivary gland cancer; precision medicine; personalized medicine
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
United Airway Disease: Current Perspectives submission deadline 30 Sep 2025 | 1 articles | Viewed by 4381 | Submission Open
Keywords: chronic rhinosinusitis; asthma; personalized medicine; type-2 inflammation; united airway; obstructive sleep apnoea; monoclonal antibodies; endotype; rhinology
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Treatment of Neurological Diseases submission deadline 30 Sep 2025 | 1 articles | Viewed by 3395 | Submission Open
Keywords: neurological diseases; neurodegenerative diseases; Alzheimer’ s disease; Parkinson’ s disease; neurodegeneration; dementia; epilepsy
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Personalized Medicine in Infectious Diseases submission deadline 30 Sep 2025 | 1 articles | Viewed by 2096 | Submission Open
Keywords: infectious diseases; genetic predisposition; post-acute infection syndromes; long-COVID; response; potential adverse events; and duration of protection of vaccines; response to therapy and development of resistance; personalized medicine; precision diagnostics; treatment strategies
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
Updates on Heart Valve Diseases: Personalized Treatment and Management
edited by Chiara Tessari
submission deadline 30 Sep 2025 | 2 articles | Viewed by 1957 | Submission Open
Keywords: heart valve disease; congenital heart valve disease; transcatheter valve implantation/replacement; surgical technique; device technology; tissue engineering; structural valve deterioration; device failure/success
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Advances in Prenatal Diagnosis and Maternal Fetal Medicine submission deadline 30 Sep 2025 | 2 articles | Viewed by 1013 | Submission Open
Keywords: prenatal diagnosis; maternal– fetal medicine; fetal anomalies; genetic screening; fetal imaging; non-invasive prenatal testing (NIPT); obstetric care; perinatal outcomes; diagnostic technologies; artificial intelligence
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
Orthopedic Diseases: Surgical Treatments and Personalized Rehabilitation Strategies
edited by Eyal Yaacobi
submission deadline 30 Sep 2025 | 1 articles | Viewed by 616 | Submission Open
Keywords: orthopedic treatment; surgical technics; limb salvage; rehabilitation
(This special issue belongs to the Section Clinical Medicine, Cell, and Organism Physiology)
New Progress in Prevention and Personalized Treatment for Cardiovascular Diseases submission deadline 30 Sep 2025 | Viewed by 401 | Submission Open
Keywords: vascular medicine; hypertension; heart failure; multimorbidity; lifestyle changes; venous thromboembolic disease (VTE); cardiovascular risk; chronic coronary artery disease; cardiovascular therapy; atherosclerosis; systemic inflammation
(This special issue belongs to the Section Personalized Therapy and Drug Delivery)
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