Cytochrome P450 Variation in Pharmacogenomics

Dear Colleagues:

On behalf of the Journal of Personalized Medicine, we invite you to submit papers for a Special Issue that I have been asked to Guest Edit, on the topic of “Cytochrome P450 Variation in Pharmacogenomics”.

Cytochrome P450s feature in a very large number of the most clinically-relevant gene–drug pairs (https://cpicpgx.org/genes-drugs/) identified by the Clinical Pharmacogenetics Implementation Consortium (CPIC). Because of the importance of this multi-enzyme family to drug metabolism, disposition and drug response, a comprehensive update on cytochrome P450 pharmacogenomics, specifically, is overdue.

Therefore, the goal is to compile a Special Issue spanning basic research on P450 pharmacogenetics through clinical implementation. Submissions can be original research articles, reviews or commentaries.

While the polygenic nature of drug response in a given therapeutic area may necessitate some discussion of non-P450 genes, the emphasis in all submitted manuscripts should stay squarely on P450 pharmacogenomics, as this tight focus will differentiate this Special Issue from many other compilations in the field.

Sincerely,
Allan Rettie
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Personalized Medicine is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.