Advances in Antithrombotic Therapy in Cardiovascular Medicine
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiovascular Medicine".
Deadline for manuscript submissions: 15 March 2026 | Viewed by 5
Special Issue Editors
Interests: percutaneous coronary intervention; myocardial infarction; coronary artery disease; vascular imaging; angiography
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Antithrombotic therapy represents a cornerstone of cardiovascular medicine and is going through continuous evolution driven by advances in pharmacology, clinical trial evidence, and refined patient stratification. While antiplatelet and anticoagulant agents have dramatically reduced ischemic events across the spectrum of cardiovascular diseases—from acute coronary syndromes (ACSs) to atrial fibrillation and peripheral artery disease—their use remains challenged by a delicate balance between ischemic protection and bleeding risk.
In recent years, major efforts have been made to tailor antithrombotic regimens to the individual patient, moving away from a “one-size-fits-all” approach. This includes strategies for antiplatelet therapy modulation, consisting of different strategies to escalate or de-escalate the intensity of antiplatelet therapy. At the same time, novel agents such as factor XI inhibitors or subcutaneous P2Y12 receptor inhibitors are at different stages of clinical investigation, aiming to optimize the trade-off between ischemia and bleeding.
This Special Issue will cover key advances in the field of antithrombotic therapy in cardiovascular medicine, including antiplatelet therapy in coronary artery disease and modulation strategies, antithrombotic strategies in high-risk or complex PCI, and emerging pharmacological agents targeting thrombosis and coagulation. Special attention will also be given to the management of bleeding complications, perioperative antithrombotic strategies, and the implementation of guideline recommendations.
Dr. Daniele Giacoppo
Dr. Antonio Greco
Guest Editors
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Keywords
- anticoagulant
- antiplatelet
- antithrombotic therapy
- cardiovascular pharmacotherapy
- coronary artery disease
- in-flammation
- lipid-lowering drugs
- lipid metabolism
- residual cardiovascular risk
- thrombosis
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