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Journal of Clinical Medicine publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Digestive Disorders: Updates on Disease Monitoring, Prediction Models and Management

edited by

Georgiana-Emmanuela Gîlcă-Blanariu

and

Catalina Mihai

submission deadline 20 Sep 2026 | Viewed by 177 | Submission Open

Keywords: inflammatory bowel disease; metabolic dysfunction-associated fatty liver disease; liver disease; alcohol related liver disease; infection; Clostridioides difficile infection

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Clinical Applications and Advances in Anesthesia and Pain Management

edited by

Tobias Kammerer

submission deadline 20 Sep 2026 | Viewed by 177 | Submission Open

Keywords: anesthesia; pain management; perioperative care; multimodal analgesia; ERAS; opioid-sparing; regional anesthesia; outcome-driven monitoring

(This special issue belongs to the Section Anesthesiology)

Diagnosis, Treatment and Comorbidities in Chronic Obstructive Pulmonary Disease (COPD): 3rd Edition

edited by Juan Luis Rodriguez Hermosa, José Luis Álvarez-Sala Walther and Myriam Calle Rubio

submission deadline 20 Sep 2026 | Viewed by 175 | Submission Open

Keywords: COPD; diagnosis; comorbidities; respiratory rehabilitation; inhaled therapy; biological therapies

(This special issue belongs to the Section Respiratory Medicine)

The Role of Cardiovascular Imaging in Pericardial, Myocardial and Vascular Inflammation

edited by

Sophie I. Mavrogeni

submission deadline 20 Sep 2026 | Viewed by 171 | Submission Open

Keywords: inflammatory cardiovascular disease; pericarditis; myocarditis; inflammatory cardiomyopathy; echocardiography; nuclear techniques; cardiac computed tomography; cardiovascular magnetic resonance; arrhythmia; heart failure

(This special issue belongs to the Section Cardiology)

Clinical Strategies in Structural Heart and Cardiothoracic Interventions

edited by

Adam Rdzanek

submission deadline 20 Sep 2026 | Viewed by 166 | Submission Open

Keywords: structural heart disease; heart team; valvular heart disease; cardiac surgery; transcatheter interventions; patient selection; real-world outcomes

(This special issue belongs to the Section Cardiology)

Multifactorial Causation and Therapy of Sleep Disorders

edited by

Anna Szûcs

submission deadline 20 Sep 2026 | Viewed by 165 | Submission Open

Keywords: sleep disorders; narcolepsy; sleep-neurology; REM sleep behavior disorder; sleep apneas

(This special issue belongs to the Section Clinical Neurology)

Advanced Technologies in Orthopedic Surgery: Progress, Challenges and Opportunities

edited by

Antonio Silvestre-Muñoz

and Daniel Pérez-Prieto

submission deadline 20 Sep 2026 | Viewed by 164 | Submission Open

Keywords: orthopedic surgery; traumatology; orthopedic infections; osteomyelitis; prosthetic joint infections; robotic-assisted surgery; biomaterials; 3D printing surgical planning; AI in orthopedics

(This special issue belongs to the Section Orthopedics)

Diagnosis and Treatment in Chronic Obstructive Pulmonary Disease

edited by Michael Kassirer

submission deadline 20 Sep 2026 | Viewed by 162 | Submission Open

Keywords: COPD phenotyping; biomarkers; precision medicine; symptom-centered care; comorbidities

(This special issue belongs to the Section Respiratory Medicine)

Advances in Burn Management—2nd Edition

edited by Juan P. Barret

submission deadline 20 Sep 2026 | Viewed by 159 | Submission Open

Keywords: burns; wound healing; immune response; stem cells; burn surgery; rehabilitation; PROMs; PREMs

(This special issue belongs to the Section General Surgery)

Clinical Management of Thyroid Diseases

edited by Diana Loreta Pãun, Mihaela Stanciu and Mihaela Popescu

submission deadline 20 Sep 2026 | Viewed by 155 | Submission Open

Keywords: thyroid genetics; autoimmune thyroiditis; thyroid cancer; thyroid puncture techniques; radiofrequency ablation treatment

(This special issue belongs to the Section Endocrinology & Metabolism)

Novel Clinical Applications of Cardiac Magnetic Resonance Imaging

edited by Bobby Heydari

submission deadline 20 Sep 2026 | Viewed by 154 | Submission Open

Keywords: cardiac magnetic resonance; CMR; cardiovascular imaging; tissue characterization; cardiomyopathy; myocardial ischemia; advanced imaging techniques; artificial intelligence; tissue mapping; quantitative stress perfusion; 4D flow; spectroscopy

(This special issue belongs to the Section Cardiology)

Mitral Valve Surgery: Current Status and Future Challenges—2nd Edition

edited by Antonio Lio and Marco Russo

submission deadline 20 Sep 2026 | Viewed by 153 | Submission Open

Keywords: mitral valve; mitral valve repair; mitral valve replacement; minimally invasive surgery; robotic surgery

(This special issue belongs to the Section Cardiology)

Supportive Care Across Proton and Photon Radiotherapy: Access, Challenges, and Solutions

edited by Safora Johansen

submission deadline 20 Sep 2026 | Viewed by 152 | Submission Open

Keywords: photon therapy; PBT; supportive care; cancer patients; caregivers; access to care

(This special issue belongs to the Section Oncology)

Pancreato-Biliary Interventional Endoscopy: 3rd Edition

edited by

Hiroyuki Isayama

submission deadline 20 Sep 2026 | Viewed by 148 | Submission Open

Keywords: endotherapy; pancreatobiliary disease; pancreatobiliary endoscopy; interventional EUS; ERCP; biliary access; biliary cannulation; endoscopic stenting; biliary drainage; pancreatic drainage; EUS-guided biliary drainage (EUS-BD); EUS-guided pancreatic drainage (EUS-PD); cholangioscopy

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Novel Diagnostic and Therapeutic Methods in Jaundice and Related Diseases

edited by

Theodoros Androutsakos

and Angela C Cheung

submission deadline 20 Sep 2026 | Viewed by 144 | Submission Open

Keywords: primary biliary cholangitis; Alagille syndrome; cholestasis; familial intrahepatic cholestasis; ileal bile acid transporters inhibitors; pruritus

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Comprehensive Management of Colonic Diverticulitis: Current Perspectives and Treatment Guidelines

edited by

Guido Zanghì

submission deadline 20 Sep 2026 | Viewed by 141 | Submission Open

Keywords: acute diverticulitis; diverticular disease; complicated diverticulitis; Hinchey classification; colonic diverticulitis; non-operative management; antibiotic stewardship; laparoscopic colectomy; Hartmann’ s procedure

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Management of Dyslipidemias: Enhancing Lipid Modification to Reduce Cardiovascular Risk: 2nd Edition

edited by

Daniel Gaudet

and Etienne Khoury

submission deadline 20 Sep 2026 | Viewed by 138 | Submission Open

Keywords: cardiovascular disease; dyslipidemia; lipoprotein remnant; emerging lipid-lowering therapies; rare and severe causes of atherogenic lipid disorders; cardiovascular risk-related biomarkers; drug safety and efficacy

(This special issue belongs to the Section Cardiovascular Medicine)

Emerging Therapeutic Interventions for Eating Disorders Through Psychology

edited by Anita Federici and

Jennifer Mills

submission deadline 20 Sep 2026 | Viewed by 136 | Submission Open

Keywords: eating disorders; psychological interventions; emerging psychotherapies; dialectical behavior therapy (DBT); transdiagnostic approaches; emotion regulation; severe and enduring eating disorders; treatment development and adaptation; implementation and feasibility; integrated medical– psychological care

(This special issue belongs to the Section Mental Health)

Stroke Recovery and Neuroplasticity: Bridging Research to Rehabilitation

edited by

Chiara Pappalettera

submission deadline 20 Sep 2026 | Viewed by 130 | Submission Open

Keywords: stroke; neuroplasticity; artificial intelligence; EEG; neuromodulation; TMS; tDCS; tACS; functional recovery prediction

(This special issue belongs to the Section Clinical Neurology)

Current Concepts in Prostate Cancer: From Early Detection to Therapeutic Innovations

edited by

Alessio Paladini

Giovanni Cochetti

and Igor Duquesne

submission deadline 20 Sep 2026 | Viewed by 125 | Submission Open

Keywords: prostate cancer; miRNA; PSMA PET/CT; radiomics; multiparametric MRI (mpMRI); active surveillance; robot-assisted radical prostatectomy (RARP); focal therapy; functional outcomes; Quality of Life (QoL)

(This special issue belongs to the Section Oncology)

Advances in Systemic Therapy for Cholangiocarcinoma: Current Evidence and Emerging Approaches

edited by

Hyunho Kim

and

Se Jun Park

submission deadline 20 Sep 2026 | Viewed by 118 | Submission Open

Keywords: cholangiocarcinoma; systemic therapy; targeted therapy; biomarkers; precision medicine; translational oncology

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

New Perspectives in the Diagnosis and Management of Skin Cancer

edited by Emily Avitan-Hersh

submission deadline 20 Sep 2026 | Viewed by 93 | Submission Open

Keywords: skin cancer; melanoma; cutaneous lymphoma; Kaposi; Merkel cell carcinoma; basal cell carcinoma; immunotherapy

(This special issue belongs to the Section Dermatology)

Clinical Advances in Prevention and Treatment of Cancer-Associated Venous Thromboembolism

edited by

Andrea D'Alessio

submission deadline 20 Sep 2026 | Viewed by 88 | Submission Open

Keywords: oncology; cancer-associated thrombosis; cancer-associated thromboembolism; venous thromboembolism; prevention; treatment; anticoagulation

(This special issue belongs to the Section Hematology)

Advances in the Clinical Management of Pregnancy-Related Complications

edited by

Panagiotis Peitsidis

submission deadline 22 Sep 2026 | 1 articles | Viewed by 638 | Submission Open

Keywords: pregnancy; complications; hypertension; diabetes; placenta accreta; preterm labor; infections

(This special issue belongs to the Section Obstetrics & Gynecology)

New Insights into Pancreatic Surgery: 2nd Edition

edited by Mario Serradilla-Martín and José Manuel Ramia

submission deadline 22 Sep 2026 | Viewed by 170 | Submission Open

Keywords: pancreas; pancreatectomy; surgery; outcomes; cancer; fistula; minimally invasive surgery; IPMT

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

The Importance of Advances in Urological Surgery: From Open Surgery to Minimally Invasive Surgery

edited by

Miguel Ángel Arrabal-Polo

submission deadline 23 Sep 2026 | 2 articles | Viewed by 1327 | Submission Open

Keywords: artificial intelligence; minimally invasive surgery; reconstructive surgical procedures; robotic surgical procedures; surgical oncology; telesurgery; virtual reality; results in urological surgery; laser in urology

(This special issue belongs to the Section Nephrology & Urology)

Improving Diagnosis and Treatment of Vestibular Disorder: Latest Advances and Challenges

edited by

Enrico Armato

Andrea Castellucci

and Athanasia Korda

submission deadline 24 Sep 2026 | 3 articles | Viewed by 8670 | Submission Open

Keywords: vestibular system; balance disorders; dizziness; vertigo; vestibular testing; videonystagmography; video head impulse test; vestibular evoked myogenic potentials; vestibular rehabilitation therapy

(This special issue belongs to the Section Otolaryngology)

Musculoskeletal Disorders: Clinical Diagnosis, Treatment and Rehabilitation

edited by

Jaime Almazán-Polo

and

César Calvo-Lobo

submission deadline 25 Sep 2026 | 8 articles | Viewed by 47942 | Submission Open

Keywords: musculoskeletal disorders; therapeutic exercise; functional evaluation; rehabilitation protocols; musculoskeletal ultrasound; biomechanical aná lisis; quality of life; functional assessment of the musculoskeletal system; strength training; physical therapy; morphofunctional assessment; conservative treatments; range of motion evaluation; randomized controlled trials

(This special issue belongs to the Section Clinical Rehabilitation)

Airway Management: From Basic Techniques to Innovative Technologies

edited by Kunal Karamchandani and Sheila Nainan Myatra

submission deadline 25 Sep 2026 | 9 articles | Viewed by 21900 | Submission Open

Keywords: airway management; physiologically difficult airway; videolaryngoscopy; esophageal intubation; artificial intelligence

(This special issue belongs to the Section Intensive Care)

Acute Care for Traumatic Injuries and Surgical Outcomes: 2nd Edition

edited by Matthias Fröhlich and Michael Caspers

submission deadline 25 Sep 2026 | 7 articles | Viewed by 10577 | Submission Open

Keywords: trauma injuries; orthopedics; polytrauma; emergency care; coagulation disorders; fractures; surgical outcomes; acute care; diagnostic imaging

(This special issue belongs to the Section Emergency Medicine)

Advances in Perioperative Care: Challenges and Perspectives in Enhanced Recovery After Surgery, Perioperative Optimization and Prehabilitation: 2nd Edition

edited by

Carlos Cerdán Santacruz

and María Rodríguez Pérez

submission deadline 25 Sep 2026 | 7 articles | Viewed by 7253 | Submission Open

Keywords: perioperative care; enhanced recovery after surgery; prehabilitation; minimally invasive surgery; patient-related outcome measures; colorectal surgery; general surgery; thoracic surgery; vascular surgery; optimal functional recovery

(This special issue belongs to the Section General Surgery)

Contemporary Trends in Cardiovascular Prevention

edited by Alessandro Durante and

Alessandro Mazzapicchi

submission deadline 25 Sep 2026 | 3 articles | Viewed by 7198 | Submission Open

Keywords: interventional cardiology; coronary artery disease; carotid artery disease; aortic valve disease; left atrial appendage closure; hypercholesterolemia

(This special issue belongs to the Section Cardiovascular Medicine)

Hepatobiliary and Pancreatic (HPB) Surgery: Current Status and Future Perspectives

edited by Andrea Benedetti Cacciaguerra and Paolo Vincenzi

submission deadline 25 Sep 2026 | 4 articles | Viewed by 6192 | Submission Open

Keywords: hepatobiliary and pancreatic surgery; laparoscopic surgery; robot-assisted surgery; artificial intelligence; augmented reality; indocyanine green; liver tumors; pancreatic tumors

(This special issue belongs to the Section Gastroenterology & Hepatopancreatobiliary Medicine)

Multiple Sclerosis and Demyelinating Diseases: Diagnosis, Treatment and Prognosis

edited by Alberto Gajofatto

submission deadline 25 Sep 2026 | 2 articles | Viewed by 5989 | Submission Open

Keywords: multiple sclerosis; neuromyelitis optica; MOG-antibody disease; diagnosis; prognosis; treatment

(This special issue belongs to the Section Clinical Neurology)

Breast Cancer: Advances in Clinical and Personalized Practices

edited by Massimo Lodi and Sébastien Molière

submission deadline 25 Sep 2026 | 4 articles | Viewed by 5716 | Submission Open

Keywords: breast cancer; radiology; surgical oncology; breast reconstruction; personalized medicine; quality of life; multidisci-plinary approach; new technologies

(This special issue belongs to the Section Oncology)

Recent Advances in Prenatal Diagnosis and Maternal Fetal Medicine

edited by

Anca Angela Simionescu

and

Ştefania Tudorache

submission deadline 25 Sep 2026 | 1 articles | Viewed by 5494 | Submission Open

Keywords: prenatal; obstetrics; fetal abnormalities; intrauterine treatments; genetic disorders; pregnancy

(This special issue belongs to the Section Obstetrics & Gynecology)

Novel Developments in Dental and Oral Surgery

edited by

Antonio Rapani

Teresa Lombardi

and

Federico Berton

submission deadline 25 Sep 2026 | 4 articles | Viewed by 4309 | Submission Open

Keywords: guided bone regeneration; dental implant osseointegration; laser dentistry; maxillofacial reconstruction; sinus lift techniques

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Acute Trauma and Trauma Care in Orthopedics: 2nd Edition

edited by

Pietro Maniscalco

and

Gianfilippo Caggiari

submission deadline 25 Sep 2026 | 5 articles | Viewed by 3963 | Submission Open

Keywords: orthopedics; trauma; injury; musculoskeletal; surgery; knee; osteoarthritis; spinal deformity; fracture; joint replacement; hip fractur; fragility fracture; minimally invasive surgery; post-traumatic care and rehabilitation; pain management; emergency assessment

(This special issue belongs to the Section Orthopedics)

Multidisciplinary Approach to the Diagnosis and Treatment of Temporomandibular Disorders: Patient Care Challenges—2nd Edition

edited by

Monika Lukomska-Szymanska

and

Klara Saczuk

submission deadline 25 Sep 2026 | 3 articles | Viewed by 3740 | Submission Open

Keywords: multidisciplinary approach; mental health; bruxism; masticatory muscles; temporomandibular joint; orofacial pain; temporomandibular disorders

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Advances in Treatment and Prognosis for Acute Type A and Type B Aortic Dissections

edited by

Katsuhiko Oda

submission deadline 25 Sep 2026 | 3 articles | Viewed by 3696 | Submission Open

Keywords: acute aortic dissection; stent graft; false lumen expansion; thoracic endovascular aortic repair; initial surgery for Type A acute aortic dissection; frozen elephant trunk

(This special issue belongs to the Section Cardiovascular Medicine)

New Insights into Acne Vulgaris Treatment and Management Strategies

edited by Jo Linda Maria Sinagra

submission deadline 25 Sep 2026 | 1 articles | Viewed by 3588 | Submission Open

Keywords: acne; hormonal treatments; isotretinoin; laser therapy; antibiotic

(This special issue belongs to the Section Dermatology)

Clinical Insights and Advances in Structural Heart Disease

edited by

David Roberts

submission deadline 25 Sep 2026 | 5 articles | Viewed by 3588 | Submission Open

Keywords: TAVR; Mitra-Clip; Tri-Clip; Pascal; TricValve; PFO closure; LAAO closure; cardiac CT; cardiac MRI; transoesopha-geal echocardiography

(This special issue belongs to the Section Cardiology)

Advances in Schizophrenia and Related Psychotic Disorders

edited by Giovanni Camardese and Michele Ribolsi

submission deadline 25 Sep 2026 | 2 articles | Viewed by 3186 | Submission Open

Keywords: psychosis; schizophrenia; severe mental illness; psychopharmacology; negative symptoms; antipsychotics

(This special issue belongs to the Section Mental Health)

Meibomian Gland Dysfunction and Dry Eye Diseases

edited by

Reiko Arita

and

KyoungYul Seo

submission deadline 25 Sep 2026 | 4 articles | Viewed by 1914 | Submission Open

Keywords: meibomian gland; meibomian gland dysfunction; dry eye disease; ocular surface; meibography; lipid layer; tear film; inflammation; therapy; diagnosis; epidemiology; clinical study

(This special issue belongs to the Section Ophthalmology)

Periodontitis and Systemic Health: Exploring the Oral-Systemic Connection

edited by

Yiorgos Bobetsis

and Phoebus Madianos

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1784 | Submission Open

Keywords: periodontal disease; systemic diseases; cardiovascular disease; diabetes mellitus; adverse pregnancy outcomes; respiratory disease; neurodegenerative disorders; obesity; respiratory diseases; chronic kidney disease

(This special issue belongs to the Section Dentistry, Oral Surgery and Oral Medicine)

Latest Advances in Ocular Surface Diseases

edited by Barbara Burgos-Blasco

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1601 | Submission Open

Keywords: cornea; keratitis; ocular surface disease; dry eye; corneal ulcer; keratoplasty; conjunctival disease

(This special issue belongs to the Section Ophthalmology)

Diagnosis and Treatment for Hearing Loss: Expert Views

edited by

Robert A. Saadi

and John L. Dornhoffer

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1589 | Submission Open

Keywords: hearing loss; cochlear implants; hearing aid technology; regenerative medicine; diagnostic audiology

(This special issue belongs to the Section Otolaryngology)

Pregnancy and Delivery Complications: Bridging Research and Clinical Practice

edited by

Maria Patricia Roman

, Andrei Mihai Malutan and Răzvan Ciortea

submission deadline 25 Sep 2026 | 2 articles | Viewed by 1581 | Submission Open

Keywords: maternal– fetal medicine; obstetric complications; perinatal health; pelvic floor disorders; childbirth perineal trauma; risk stratification; patient-reported outcomes; patient-reported outcome measures

(This special issue belongs to the Section Obstetrics & Gynecology)

Current Advances and Future Perspectives of Sepsis and Septic Shock

edited by Filippo Mearelli and Gianni Biolo

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1329 | Submission Open

Keywords: sepsis; epidemiology; biomarkers; diagnosis; predictive models; prognostication

(This special issue belongs to the Section Emergency Medicine)

Corneal Surgery: From Innovation to Clinical Practice

edited by Joanna Wasielica-Poslednik

submission deadline 25 Sep 2026 | 1 articles | Viewed by 1241 | Submission Open

Keywords: keratoplasty; penetrating keratoplasty; DMEK; eye banking; corneal surgery

(This special issue belongs to the Section Ophthalmology)

Displaying special issue 851-900 on page 18 of 31.

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