Current Challenges and New Perspectives in Liver Transplantation
A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Gastroenterology & Hepatopancreatobiliary Medicine".
Deadline for manuscript submissions: 20 March 2026 | Viewed by 128
Special Issue Editors
Interests: transplant hepatology; post-transplant outcomes; alcoholic liver disease; HCC
Interests: post-transplant outcomes; HCC; CCC; living donor; liver trasnplantation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
We would like to invite you to contribute to this Special Issue, “Current Challenges and New Perspectives in Liver Transplantation”. Liver transplantation (LT) has evolved significantly over the past few decades, becoming a life-saving treatment for various acute and chronic liver diseases. Despite major advances in surgical techniques, immunosuppression, and patient selection, LT still faces several persistent challenges, including donor organ shortage, complications from long-term immunosuppression, the recurrence of primary liver diseases, and disparities in access to transplantation. Additionally, emerging issues, such as transplantation in the context of metabolic dysfunction-associated liver disease (MASLD), hepatocellular carcinoma beyond traditional criteria, and transplantation for acute-on-chronic liver failure, are reshaping the landscape and require updated, evidence-based approaches. With the advent of precision medicine, machine learning, and minimally invasive diagnostics, new perspectives present opportunities to improve outcomes and individualized care.
This Special Issue aims to provide a comprehensive overview of the current state and future directions in liver transplantation. It seeks high-quality contributions that align with the journal’s scope by advancing our understanding of clinical research in hepatology and transplantation medicine. Our goal is to compile a diverse range of studies that reflect innovative thinking, multidisciplinary collaboration, and the latest developments in this dynamic field.
Topics of interest include (but are not limited to) the following:
- Expanding indications for liver transplantation;
- Biomarkers and imaging in transplant evaluation and follow-up;
- Post-transplant complications and immunosuppression strategies;
- Outcomes in special populations (elderly, pediatric, and HIV-positive recipients);
- Health equity and access to transplantation;
- Artificial liver support systems and bridge-to-transplant strategies;
- Recurrent and de novo malignancies post transplant;
- The role of artificial intelligence and precision medicine in transplant decision making.
Original research articles and comprehensive review papers are welcome.
We look forward to receiving your contributions and hope to advance this field of research and foster new collaborations.
Dr. Anna Mrzljak
Dr. Quirino Lai
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- liver transplantation
- graft survival
- immunosuppression
- organ allocation
- hepatocellular carcinoma
- MASLD
- donor shortage
- transplant outcomes
- innovation
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