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Skin Disease and Inflammation

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Dermatology".

Deadline for manuscript submissions: 20 March 2026 | Viewed by 967

Special Issue Editor


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Guest Editor
Department of Dermatology, University of Michigan Medical School, 1301 Catherine, Medical Science I, Room 6447, Ann Arbor, MI 48109-0609, USA
Interests: dermatology; skin aging; wound healing; ECM; skin cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue is dedicated to providing a comprehensive exploration of current research, emerging treatments, and innovative strategies for understanding and managing inflammatory skin conditions. Topics for this issue will include, but are not limited to:

  • Pathophysiology of Skin Inflammation: Investigating the mechanisms behind inflammatory responses in skin diseases such as psoriasis, eczema, and rosacea.
  • Genetic and Environmental Triggers: Examining how genetic predispositions and environmental factors contribute to the worsening of skin inflammation.
  • Diagnostic Innovations: Highlighting advances in diagnostic methods for detecting inflammatory markers associated with skin conditions.
  • Therapeutic Strategies: Discussing current and new therapies targeting inflammation, including biologics, small molecules, and lifestyle changes.
  • Impact of Inflammation on Skin Microbiome: Analyzing how inflammatory processes affect skin microbiota and their potential therapeutic implications.
  • Interdisciplinary Approaches: Integrating dermatology, immunology, and related fields to improve the understanding and treatment of inflammatory skin diseases.

We invite the submission of original research articles and comprehensive reviews that offer insights into both clinical and basic science aspects of skin inflammation. This issue is intended for dermatologists, immunologists, biomedical researchers, and healthcare professionals involved in the study and treatment of skin diseases. It will also serve as a valuable resource for students and academics with an interest in dermatology and immunology.

Prof. Dr. Taihao Quan
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • inflammatory skin diseases
  • inflammation mechanisms
  • skin microbiome
  • psoriasis
  • eczema
  • rosacea

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Published Papers (1 paper)

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Review

21 pages, 1238 KB  
Review
Current Physical Therapy for Skin Scar Management: A Scoping Review
by Sara Di Serio, Matteo Congiu, Silvia Minnucci, Valentina Scalise and Firas Mourad
J. Clin. Med. 2025, 14(17), 5920; https://doi.org/10.3390/jcm14175920 - 22 Aug 2025
Viewed by 730
Abstract
Background: Scar impairments impose a significant economic burden and negatively impact an individual’s well-being and quality of life. However, there is a lack of standardization in physical therapy interventions for scar management. Objective: This study aimed to provide a comprehensive overview of studies [...] Read more.
Background: Scar impairments impose a significant economic burden and negatively impact an individual’s well-being and quality of life. However, there is a lack of standardization in physical therapy interventions for scar management. Objective: This study aimed to provide a comprehensive overview of studies addressing non-invasive physical therapy interventions for scar management. Methods: This scoping review was conducted following the Joanna Briggs Institute (JBI) Manual for Evidence Synthesis. Six databases were searched, and additional studies were retrieved through gray literature and the reference lists of included articles. All studies considering non-invasive physical therapy interventions for scar management were included. No restrictions were applied regarding time, context or publication type. Results were illustrated using descriptive statistics and summarized in an infographic. Results: Out of 13,419 initial records, 92 studies met the inclusion criteria. Most articles were narrative reviews (n = 41) followed by randomized controlled trials (RCT) (n = 18). The most reported interventions were pressure therapy (n = 41), physical therapy modalities (n = 37), silicone-based products (n = 29) and massage (n = 20). Conclusions: Scar management involves a wide range of physical interventions. However, research has predominantly focused on adults, particularly those with burns, with limited attention given to pediatric or non-adult populations. Furthermore, there is significant variability in the application parameters, scar localization and size. Examining the included study designs, most of the research presented reduced sample sizes and lacked control groups. Notably, almost half of the studies were based on expert opinions. Future high-quality research is needed to identify evidence-based interventions for the clinical management of scars. Full article
(This article belongs to the Special Issue Skin Disease and Inflammation)
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