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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Study on Clinical Treatment of Brain Tumors
edited by Shinya Watanabe
submission deadline 13 Mar 2026 | 3 articles | Viewed by 3610 | Submission Open
Keywords: brain tumors; clinical treatment; anti-tumor drugs; clinical trials
(This special issue belongs to the Section Cancer Therapy)
Molecular Pathology of Brain Tumors
edited by Ho-Keung NG
submission deadline 15 Mar 2026 | 9 articles | Viewed by 21085 | Submission Open
Keywords: molecular pathology; brain tumors; AI; biomarkers; histopathology
(This special issue belongs to the Section Molecular Cancer Biology)
State of the Art: Cardiothoracic Tumors
edited by and Panagiotis Tasoudis
submission deadline 15 Mar 2026 | 4 articles | Viewed by 6931 | Submission Open
Keywords: lung cancer; non-small cell lung cancer; esophageal cancer; diagnostic imaging; robotic-assisted thoracoscopic surgery; video-assisted thoracoscopic surgery; immunotherapy; radiotherapy; molecular oncology; lung cancer screening
(This special issue belongs to the Section Cancer Therapy)
Novel Approaches to the Management of Patients with Gastrointestinal Tumors
edited by Javier Rodriguez and Ignacio Matos García
submission deadline 15 Mar 2026 | 1 articles | Viewed by 640 | Submission Open
Keywords: clinical management; gastric cancer; colorectal cancer; predictive factors; novel therapies; artificial intelligence
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Artificial Intelligence Methodologies and Applications in Cancer
edited by Jennifer G. Le-Rademacher and
submission deadline 15 Mar 2026 | 1 articles | Viewed by 495 | Submission Open
Keywords: artificial intelligence (AI); AI tools; cancer research; diagnostic tools; medical imaging; biomarkers; ethical considerations; patient care
(This special issue belongs to the Section Methods and Technologies Development)
Stress, Epigenetic Regulation, and DNA Damage: Insights into Cancer Development and Therapeutic Challenges
edited by Yanying Huo
submission deadline 15 Mar 2026 | Viewed by 72 | Submission Open
Keywords: ROS; oxidative stress; metabolic stress; DNA damage repair; genomic instability; cancer
(This special issue belongs to the Section Cancer Pathophysiology)
Endometrial Cancer Therapy: Foundations and Future Directions submission deadline 15 Mar 2026 | Viewed by 70 | Submission Open
Keywords: pathology; surgery; radiotherapy; chemotherapy; new agents; immunotherapy; artificial intelligence
(This special issue belongs to the Section Cancer Therapy)
Treatment of Acute Kidney Injury in Cancer Patients: From Theory to Practice
edited by and Shveta S. Motwani
submission deadline 15 Mar 2026 | Viewed by 51 | Submission Open
Keywords: immune check point inhibitor related nephritis; MGRS; CART cell therapy; stem cell transplant; TMA; BK nephropathy; cisplatin nephropathy
(This special issue belongs to the Section Cancer Therapy)
Renal Cell Carcinoma: Genetics, Surgical Management, and Systemic Therapy
edited by Alejandro Remigio Rodríguez, Stênio C. Zequi and Maxwell Sandberg
submission deadline 15 Mar 2026 | Viewed by 44 | Submission Open
Keywords: renal cell carcinoma; robotics; laparoscopy; systemic therapy; genetics; surgery; urology; disparities; tumor thrombus; cryotherapy; global health
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Lung Cancer Treatment Strategies submission deadline 15 Mar 2026 | Viewed by 20 | Submission Open
Keywords: lung cancer; immunotherapy; immune checkpoint inhibitors; chemoimmunotherapy; target therapy; biomarkers; non-small cell lung cancer; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Development of Hepatitis C Virus-Related Cancers
edited by
submission deadline 15 Mar 2026 | Viewed by 20 | Submission Open
Keywords: hepatitis C virus (HCV); hepatocellular carcinoma (HCC); extrahepatic malignancies; lymphoproliferative disorders; viral oncogenesis; chronic inflammation and cancer; direct-acting antivirals (DAAs); cancer surveillance in HCV patients
(This special issue belongs to the Section Clinical Research of Cancer)
Health Economic and Policy Issues Regarding Cancer
edited by Aviad Tur-Sinai
submission deadline 16 Mar 2026 | Viewed by 79 | Submission Open
Keywords: cancer economics; health policy; cost-effectiveness; financial toxicity; healthcare disparities; value-based oncology
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Novel Insight of MRI for Lung Cancer and Thoracic Neoplasm (2nd Edition)
edited by
submission deadline 18 Mar 2026 | Viewed by 114 | Submission Open
Keywords: oncologic imaging; cancer imaging; imaging of thoracic disease; magnetic resonance imaging (MRI); computed tomography (CT); positron emission tomography– computed tomography (PET-CT); diffusion-weighted magnetic resonance imaging (DWI); economic evaluation; imaging biomarkers
(This special issue belongs to the Section Methods and Technologies Development)
Targeted Therapy of Cholangiocarcinoma
edited by
submission deadline 19 Mar 2026 | Viewed by 70 | Submission Open
Keywords: cholangiocarcinoma; targeted therapy; molecular alterations; immunotherapy; precision medicine
(This special issue belongs to the Section Tumor Microenvironment)
Drug Targeting Therapy in Multiple Myeloma submission deadline 20 Mar 2026 | 2 articles | Viewed by 4306 | Submission Open
Keywords: multiple myeloma; novel drug; novel targets; new therapeutic targets; prognosis
(This special issue belongs to the Section Cancer Drug Development)
Cancer Survivors: Late Effects of Cancer Therapy
edited by
submission deadline 20 Mar 2026 | Viewed by 74 | Submission Open
Keywords: late effects; cancer survivorship; treatment toxicity; long-term outcomes
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Neuroendocrine Tumors: From Diagnosis to Therapy (2nd Edition)
edited by , , and Daniela Prosperi
submission deadline 20 Mar 2026 | Viewed by 25 | Submission Open
Keywords: neuroendocrine neoplasms; CT; MR; PET/CT; target therapy; quantitative biomarkers
(This special issue belongs to the Section Cancer Therapy)
Cervical Cancer Screening: Current Practices and Future Perspectives
edited by Kimon Chatzistamatiou
submission deadline 20 Mar 2026 | Viewed by 22 | Submission Open
Keywords: cervical cancer screening; cervical carcinogenesis; human papillomavirus; HPV primary screening; self-sampling; triage of HPV-positive; post-conization follow-up; screening for immunocompromised women; screening for vac-cinated women
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Radiation Therapy in Lung Tumors: Recent Trends and Current Issues
edited by and Sara Ramella
submission deadline 21 Mar 2026 | Viewed by 36 | Submission Open
Keywords: lung cancer; immunotherapy; chemotherapy; PET-CT; surgery; oligo-metastases
(This special issue belongs to the Section Cancer Therapy)
Bacterial Infections and Cancer Risk: From Biological Mechanisms to Clinical Realities
edited by and Shuai Hu
submission deadline 25 Mar 2026 | 1 articles | Viewed by 988 | Submission Open
Keywords: bacterial infections; cancer risk; biological mechanisms; treatment modalities; therapeutic strategies
(This special issue belongs to the Section Infectious Agents and Cancer)
Roles of Urokinase Receptors in Cell Biology: Modulating Tumor Cell Migration and Invasion
edited by
submission deadline 28 Mar 2026 | Viewed by 84 | Submission Open
Keywords: urokinase-type plasminogen receptor; uPAR; inflammation; cancer; migration; invasion
(This special issue belongs to the Section Molecular Cancer Biology)
Cancer Immunotherapy: Focus on Immune Checkpoint Inhibitors and Immune Modulators
edited by
submission deadline 30 Mar 2026 | 4 articles | Viewed by 5811 | Submission Open
Keywords: PD-1; PD-L1; CTLA-4; immune checkpoint molecule; immune checkpoint inhibitor; tumor microenvironment; drug resistance; biomarker; BiTE; BiCE
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Neoadjuvant Therapy for Pancreatic Cancer
edited by Brice Chanez
submission deadline 30 Mar 2026 | Viewed by 120 | Submission Open
Keywords: induction treatment; biomarkers; chemotherapy
(This special issue belongs to the Section Cancer Therapy)
Quality and Clinical Outcomes Improvement in the Management of Oncology Patients (2nd Edition) submission deadline 30 Mar 2026 | Viewed by 37 | Submission Open
Keywords: oncology; surgical oncology; quality improvement; clinical outcomes; patient safety
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Women’s Health and Gynaecological Cancers: From Nutrition and Environmental Factors to Novel Diagnostics and Therapies submission deadline 31 Mar 2026 | 10 articles | Viewed by 20853 | Submission Open
Keywords: breast cancer; ovarian cancer; cervical cancer; endometrial cancer; nutrition; obesity; environmental factors; women's health; gynaecological cancers
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Recent Advances in Hepatobiliary Cancers: From Diagnosis to Treatment (2nd Edition)
edited by
submission deadline 31 Mar 2026 | 9 articles | Viewed by 15811 | Submission Open
Keywords: hepatobiliary cancers; hepatocellular carcinoma; cholangiocarcinoma; gallbladder cancer; immunotherapy; targeted therapy; precision medicine
(This special issue belongs to the Section Cancer Therapy)
PET/CT and Conventional Imaging in Cancers submission deadline 31 Mar 2026 | 6 articles | Viewed by 12495 | Submission Open
Keywords: PET/CT; CT; MR; conventional imaging; positron emission tomography; neoplasm; cancer
(This special issue belongs to the Section Methods and Technologies Development)
Gastric Cancer Surgery: Gastrectomy, Risk, and Related Prognosis submission deadline 31 Mar 2026 | 4 articles | Viewed by 6382 | Submission Open
Keywords: gastric cancer; surgical treatment; gastrectomy; outcome; minimally invasive surgical
(This special issue belongs to the Section Clinical Research of Cancer)
Biomarkers for Gynecological Cancers submission deadline 31 Mar 2026 | 5 articles | Viewed by 5312 | Submission Open
Keywords: biomarkers; cervical; ovarian; uterine; endometrial; vaginal; vulvar; fallopian tube
(This special issue belongs to the Section Cancer Biomarkers)
Advancements in Treatment Approaches for AML submission deadline 31 Mar 2026 | 3 articles | Viewed by 4711 | Submission Open
Keywords: AML treatment; allogeneic HSCT; novel targeted therapeutic agents; diagnostic; treatment strategies
(This special issue belongs to the Section Methods and Technologies Development)
The Oral Microbiome and Its Link to Oral Cancer: Exploring the Role of Infectious Agents
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 3082 | Submission Open
Keywords: oral microbiome; oral cancer; infectious agents; microbial dysbiosis; host– microbe interactions
(This special issue belongs to the Section Infectious Agents and Cancer)
Advances in Invasive Breast Cancer: Treatment and Prognosis (2nd Edition)
edited by and Emmanouil Saloustros
submission deadline 31 Mar 2026 | 4 articles | Viewed by 2741 | Submission Open
Keywords: ER+/HER2– breast cancer; HER2+ breast cancer; triple-negative breast cancer; treatment toxicity and quality of life; survivorship issues
(This special issue belongs to the Section Cancer Therapy)
Advances in Renal Cell Carcinoma
edited by Philipp Ivanyi and Hendrik Eggers
submission deadline 31 Mar 2026 | 3 articles | Viewed by 2571 | Submission Open
Keywords: renal cell carcinoma; treatment; metastatic; prediction; medical treatment; immunotherapy; multimodal therapy; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
Intratumoral Heterogeneity in Brain Cancers
edited by Michael Oldham
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2562 | Submission Open
Keywords: intratumoral heterogeneity; brain; clonal evolution; tumor microenvironment; multiomics
(This special issue belongs to the Section Molecular Cancer Biology)
Cardio-Oncology: An Emerging Paradigm in Modern Medicine: 2nd Edition
edited by Rohit Moudgil
submission deadline 31 Mar 2026 | 3 articles | Viewed by 2533 | Submission Open
Keywords: cardio-oncology; CTRCD; arrhythmias; anthracyclines; anti-her2 therapies; immune checkpoint inhibitors; artificial intelligence; guidelines; emerging research
(This special issue belongs to the Section Cancer Therapy)
Immunotherapy in Urothelial Carcinoma
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1734 | Submission Open
Keywords: bladder cancer; upper tract urothelial carcinoma; immune checkpoint inhibitors; tumor microenvironment; biomarkers for immunotherapy; combination therapy; neo-adjuvant/adjuvant immunotherapy; resistance mechanisms; novel immunotherapeutic approaches; personalized medicine
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
The Role of Viruses in the Development of Cancer
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1407 | Submission Open
Keywords: DNA and RNA tumour viruses; HPV; EBV; KSHV; HCV; HBV; HTLV1; McPyV
(This special issue belongs to the Section Infectious Agents and Cancer)
The EGFR-Tyrosine Kinase Inhibitors (EGFR-TKIs) and Immune Checkpoint Inhibitors (ICIs) for Non-Small Cell Lung Cancer submission deadline 31 Mar 2026 | 1 articles | Viewed by 1103 | Submission Open
Keywords: non-small cell lung cancer; target therapy; EGFR-tyrosine kinase inhibitors; immunotherapy; immune checkpoint inhibitors; molecular analysis; surgery; precision medicine
(This special issue belongs to the Section Cancer Therapy)
Minimally Invasive Therapies in Urologic Cancers
edited by Eric M. Walser and
submission deadline 31 Mar 2026 | 1 articles | Viewed by 716 | Submission Open
Keywords: laparoscopic surgery; robotic-assisted surgery; ablation; high-intensity focused ultrasound; partial nephrectomy; minimally invasive procedures; urologic cancers
(This special issue belongs to the Section Methods and Technologies Development)
Development of Biomarkers and Antineoplastic Drugs in Solid Tumors
edited by , Sofia Verkhovskaia and Michela Roberto
submission deadline 31 Mar 2026 | 1 articles | Viewed by 601 | Submission Open
Keywords: solid tumors; drugs; biomarkers; immunotherapy; targeted therapy; artificial intelligence
(This special issue belongs to the Section Cancer Drug Development)
Exercise Interventions for People Living with Cancer: Advances in Knowledge and Implementation
edited by and Chris Swain
submission deadline 31 Mar 2026 | Viewed by 534 | Submission Open
Keywords: cancer; survivorship; exercise; physical activity; implementation
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Colorectal Cancer Liver Metastases submission deadline 31 Mar 2026 | 1 articles | Viewed by 528 | Submission Open
Keywords: liver metastases; colorectal cancer; treatment; imaging; oncologic strategy
(This special issue belongs to the Section Cancer Metastasis)
Significance of KRAS Gene Mutations in Colorectal Cancer (2nd Edition) submission deadline 31 Mar 2026 | 1 articles | Viewed by 509 | Submission Open
Keywords: KRAS; colorectal cancer; target therapy; mechanism; treatment targets
(This special issue belongs to the Section Molecular Cancer Biology)
Advances on Imaging and Treatment of Head and Neck Cancer
edited by Yading Yuan, Vishruta A. Dumane, and Luqman Dad
submission deadline 31 Mar 2026 | Viewed by 354 | Submission Open
Keywords: head and neck cancer; medical imaging; robotic surgery; image-guided radiation therapy; proton radiotherapy; online adaptive radiotherapy; artificial intelligence; machine learning
(This special issue belongs to the Section Cancer Therapy)
The Development of Immunotherapies to Treat Lymphoma submission deadline 31 Mar 2026 | 1 articles | Viewed by 238 | Submission Open
Keywords: lymphoma immunotherapy; CAR T-cell therapy; immune checkpoint inhibitors; monoclonal antibodies; personalized immunotherapy
Proteomics in Skin Cancer: Recent Advances
edited by and Beatrice Dyring-Andersen
submission deadline 31 Mar 2026 | Viewed by 107 | Submission Open
Keywords: proteomics; skin cancer; mass spectrometry; melanoma; non-melanoma skin cancers; biomarkers
(This special issue belongs to the Section Molecular Cancer Biology)
Imaging and Liquid Biopsy Biomarkers for Cancer Diagnosis and Treatment (2nd Edition) submission deadline 31 Mar 2026 | Viewed by 105 | Submission Open
Keywords: cancer imaging; liquid biopsy; cancer diagnosis; treatment response; prognosis; metastasis; circulating tumor cells; disseminated tumor cells; circulating tumor DNA; circulating tumor RNA
(This special issue belongs to the Section Methods and Technologies Development)
Pioneering Advances in Neurosurgical Oncology: From Innovative Techniques to Better Patient Outcomes submission deadline 31 Mar 2026 | Viewed by 101 | Submission Open
Keywords: endoscope; 3D exoscope; tractography MRI; molecular biomarkers; stem cells; transoral; cordomas; skullbase
(This special issue belongs to the Section Methods and Technologies Development)
Immune Landscape of Multiple Myeloma
edited by Muhamed Baljevic and
submission deadline 31 Mar 2026 | Viewed by 99 | Submission Open
Keywords: myeloma; immune; T cells; therapy; fitness
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Genetic Alterations and the Tumor Microenvironment
edited by Shanye Yin
submission deadline 31 Mar 2026 | Viewed by 91 | Submission Open
Keywords: tumor microenvironment; cancer immunology; immune checkpoint blockade; somatic mutations; T cell signaling; immune evasion; macrophage polarization; cancer immunotherapy resistance; single-cell transcriptomics; spatial analysis
(This special issue belongs to the Section Tumor Microenvironment)
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