Cancers in Chronic HIV Infection
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Infectious Agents and Cancer".
Deadline for manuscript submissions: 31 December 2025 | Viewed by 133
Special Issue Editor
Special Issue Information
Dear Colleagues,
HIV increases the risk of developing cancer, and it has been considered a carcinogenic since 1996. The combination antiretroviral therapy (cART) and the subsequent immune restoration leads to a significant reduction in the incidence of AIDS-defining cancers in people with HIV (PWH); however, the incidence of cancer is still much higher in HIV patients than in the general population. In addition, non-AIDS-defining cancers (such as liver and anal cancers) are also increasing in number as a consequence of persistent immune system dysregulation, even after long-term virological suppression and a robust immune recovery.
Modern HIV pharmacology has successfully turned this deadly disease into a chronic condition. Cancers are becoming critical comorbidities in aging PWH due to concomitant infections with oncogenic viruses, accelerated aging, and higher prevalence of risk factors. Thus, HIV patients are exposed to infection-related and infection-unrelated cancers, as primary or secondary malignancies.
The aim of this Special Issue is to refocus the attention of healthcare providers, going beyond the undetectable viral load, reshaping clinical management, and supporting both proactive screening and preventive strategies. In this Special Issue of Cancers, we welcome original research articles or comprehensive reviews focusing on cancer risk, types of malignancies, pathogenesis, barriers in diagnosing, treatment disparities, treatment outcomes, and preventive strategies. We look forward to your submissions.
Dr. Diego Ripamonti
Guest Editor
Manuscript Submission Information
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Keywords
- cancer
- HIV
- AIDS
- cancer screening
- hematologic malignancy
- Kaposi sarcoma
- HPV
- anal cancer
- lymphoma
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