Recent Advances in Liquid Biopsy Biomarkers of Cancer
A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Biomarkers".
Deadline for manuscript submissions: 15 January 2026 | Viewed by 58
Special Issue Editor
Interests: cancer biomarker; standards development; assay standardization; liquid biopsy; regenerative medicine
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Liquid biopsy has emerged as a minimally invasive method for cancer detection, prognosis, treatment decision guidance, and monitoring. It detects cancer-related biomarkers, including circulating tumor cells, cell-free DNA, cell-free RNA, miRNA, extracellular vesicles, proteins, lipids, and metabolites present in the bodily fluids of patients. These biospecimens can be easily and reproducibly collected for analysis. The rapid advances in sequencing technologies, AI, and other emerging technologies have the potential to enhance the utility of liquid biopsy biomarkers for early cancer detection and multi-cancer detection. However, there are still limitations and challenges in liquid biopsy, such as a lack of laboratory standardization. It is crucial to ensure the accuracy and reliability of these test results for clinical utility.
We invite you to contribute to this Special Issue, titled "Recent Advances in Liquid Biopsy Biomarkers of Cancer". It will focus not only on the discovery of novel cancer biomarkers, such as genetic, epigenetic, proteomic, circulating microbial DNA, fragmentome, and metabolic markers in liquid biopsy for clinical applications, but also on analytical assay development, validation, and reference material development for these biomarker measurements. Additionally, we will explore emerging tools and advanced computational methodologies for detecting cancer biomarkers in liquid biopsy.
For this Special Issue, we welcome original research articles, reviews, and perspective or opinion pieces discussing challenges and future directions in the field.
We look forward to receiving your contributions.
Dr. Hua-Jun He
Guest Editor
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- liquid biopsy
- circulating tumor cells
- circulating tumor DNA
- extracellular vesicles
- circulating RNA
- cfDNA methylation
- fragmentome
- reference material
- miRNA
- multi-cancer detection
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