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Cancers
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Patients’ Perspective in Gynecological Cancer
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Patients’ Perspective in Gynecological Cancer

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Survivorship and Quality of Life".

Deadline for manuscript submissions: closed (28 February 2026) | Viewed by 487

Special Issue Editor

Prof. Dr. Jalid Sehouli

E-Mail Website
Guest Editor
Department of Gynecology with Center for Oncological Surgery, Virchow Campus Clinic, Charité Medical University, Augustenburger Platz 1, 13353 Berlin, Germany
Interests: cervical cancer; endometriosis prevention; gynecologic oncology; gynecological surgery; cancer chemotherapy; cancer immunotherapy; cancer care facilities; ovarian cancer
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue will explore how the perspectives and expectations of patients play crucial roles in treatment decision-making for women with gynecological malignancies. Despite growing awareness of this issue, research on patient perspectives in breast, cervical, ovarian, and endometrial cancers remains limited. This Special Issue will highlight the importance of these topics, focusing on clinical trials, patient surveys, and expert statements.

In this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following:

  • Patient perspective;
  • Expectations;
  • PROMs;
  • Quality of life;
  • Best supportive care.

We look forward to receiving your contributions.

Prof. Dr. Jalid Sehouli
Guest Editor

Jolijn Boer
Guest Editor Assistant

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • patient perspective
  • expectations
  • PROMs
  • quality of life
  • best supportive care

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Published Papers (1 paper)

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Research

17 pages, 511 KB  
Article
Patients’ Perception of Follow-Up Care and Personal Health Status of 677 Long-Term Survivors of Gynecological Cancer from the Study “Expression IX—Long-Term Survival with Gynecological Cancer”: The International NOGGO, ENGOT and GCIG Survey
by Hannah Woopen, Tibor Zwimpfer, Luise Brenner, Clemens Liebrich, Katharina Leitner, Stephanie Henry, Cornelia Müller, Flurina Annacarina Maria Saner, Christoph Ebner, Desislava Dimitrova, Claudia Mang, Isabelle Himsl, Johanna Hell-Teutsch, Toon Van Gorp, Christian Braun, Yurtcu Nurhayat, Michael Müller, Lars Hanker, Viola Heinzelmann-Schwarz and Jalid Sehouli
Cancers 2026, 18(10), 1647; https://doi.org/10.3390/cancers18101647 - 20 May 2026
Abstract
Background: Long-term survivors (LTS) after gynecological cancer may be cured but still face physical and psychological challenges. This multicenter study aimed to assess the long-term side effects, the received follow-up care, and the personal perspectives of survivors. Methods: Between 2019 and 2025, LTS [...] Read more.
Background: Long-term survivors (LTS) after gynecological cancer may be cured but still face physical and psychological challenges. This multicenter study aimed to assess the long-term side effects, the received follow-up care, and the personal perspectives of survivors. Methods: Between 2019 and 2025, LTS from four European countries within the ENGOT (European Network of Gynecological Oncological Trial Groups) and GCIG (Gynecologic Cancer InterGroup) networks were recruited. Long-term survival was defined as surviving at least five years after the first diagnosis. LTS completed a questionnaire with 81 questions (patient’s characteristics, oncological history, current health status, lifestyle factors). Analyses were mainly descriptive. Results: A total of 677 LTS were enrolled, with a median age of 64.0 years (range: 26–92) and a median survival time of 7 years (range: 5–38). A total of 46.6% were diagnosed with cervical cancer, 32.9% with endometrial cancer, 4.4% with ovarian cancer, and 16.1% with other types of gynecological cancer. Moreover, 36.9% still suffer from physical and psychological symptoms, most frequently being lymphedema (36.2%), hot flashes (22.4%), difficulties with concentration (21.1%), fatigue (20.9%), vaginal dryness (20.1%), and urinary incontinence (18.9%). Median overall health status was ranked (scale 1–5; 1 = very good, 5 = very poor) as 2, while 13.5% rated their health as poor/very poor. Current symptoms were associated with poorer health status (p < 0.001) and a history of recurrent disease (p = 0.001). In addition, 13.6% reported not receiving follow-up care. CA-125 was determined in 80.8% of ovarian LTS, as well as in 30.7% of cervical and 28.9% of endometrial LTS. Pap smear follow-up was reported by 50.5% of endometrial LTS. A total of 33.7% did not exercise at all or exercised less than an hour per week, 13.4% smoke tobacco, and 51.2% drink alcohol more often than once a month. Conclusions: Our findings highlight the need for patient-centered follow-up care, addressing both long-term side effects and education on lifestyle and prevention. Follow-up procedures that do not follow guidelines should be avoided. Full article
(This article belongs to the Special Issue Patients’ Perspective in Gynecological Cancer)
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