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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gynecologic Cancer: From Diagnosis to Treatment: 2nd Edition submission deadline 30 Oct 2026 | Viewed by 35 | Submission Open
Keywords: endometrial cancer; cervical cancer; ovarian cancer; borderline ovarian tumor; diagnosis and treatment
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Oncologic Pathology: Diagnostic Challenges, Molecular Advances, and Clinical Correlations submission deadline 31 Oct 2026 | Viewed by 105 | Submission Open
Keywords: solid neoplasia; predictive and prognostic biomarkers; target therapy; tumor microenvironment; molecular biology
(This special issue belongs to the Section Cancer Pathophysiology)
Molecular Targets and Therapeutic Pathways in Cancer
edited by Ashish H. Shah and Deepa Seetharam
submission deadline 31 Oct 2026 | Viewed by 85 | Submission Open
Keywords: cancer therapeutics; molecular targets; signal transduction pathways; targeted therapy; drug resistance; precision oncology; tumor microenvironment; immunotherapy; kinase inhibitors; translational cancer research
(This special issue belongs to the Section Cancer Drug Development)
Omics Data for Cancer Therapies: From Molecular Profiling to Clinical Applications
edited by
submission deadline 31 Oct 2026 | Viewed by 84 | Submission Open
Keywords: multi-omics integration; precision oncology; biomarker discovery; computational oncology; translational cancer research
(This special issue belongs to the Section Cancer Informatics and Big Data)
The Tumor Microenvironment and Its Role in Tumor Growth and Angiogenesis—2nd Edition
edited by
submission deadline 31 Oct 2026 | Viewed by 24 | Submission Open
Keywords: tumor microenvironment; tumor angiogenesis; tumor targeted therapies; inflammation; immunotherapies
(This special issue belongs to the Section Tumor Microenvironment)
Role of Pathology in Detection, Prognosis and Treatment of Gastrointestinal Cancers
edited by and Luís Ortega-Medina
submission deadline 31 Oct 2026 | Viewed by 11 | Submission Open
Keywords: gastrointestinal cancer; pathology; histopathology; molecular pathology; biomarkers; prognosis; precision medicine; digital pathology; cancer detection; targeted therapy
(This special issue belongs to the Section Cancer Pathophysiology)
Oral Cancer and Precancerous Lesions: Advances in Diagnosis, Prognosis, and Therapy submission deadline 31 Oct 2026 | Viewed by 11 | Submission Open
Keywords: potentially malignant oral disorders (PMODs); malignant transformation; oral cancer and precancerous lesions
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
New Findings in Targeting Cancer Proteins (Second Edition) submission deadline 30 Nov 2026 | Viewed by 92 | Submission Open
Keywords: monoclonal antibodies; protein target; immunotherapy; signaling blockade; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
New Approaches to Surgical Treatment and Care for Urological Cancer
edited by and Bente Thoft Jensen
submission deadline 30 Nov 2026 | Viewed by 52 | Submission Open
Keywords: bladder cancer; prostate cancer; kidney cancer; penile cancer; patient perspective; patient education; enhanced recovery after surgery (ERAS) protocols; prehabilitation rehabilitation; sexual health
(This special issue belongs to the Section Clinical Research of Cancer)
Artificial Intelligence and Machine Learning in Lung Cancer Screening: Current Applications and Future Directions submission deadline 30 Nov 2026 | Viewed by 9 | Submission Open
Keywords: artificial intelligence; machine learning; lung cancer screening; low-dose CT; early detection
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
Immunotherapy with Checkpoint Inhibitors for Non-Small-Cell Lung Cancer (2nd Edition) submission deadline 30 Dec 2026 | Viewed by 87 | Submission Open
Keywords: immune-checkpoint inhibitors; non-small cell lung cancer; neoadjuvant therapy; adjuvant therapy; primary resistance; acquired; resistance; biomarkers; immune-related adverse events
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
CancersScape: Spatial Biology of the Tumor Ecosystem
edited by and Sammy Ferri-Borgogno
submission deadline 31 Dec 2026 | Viewed by 317 | Submission Open
Keywords: cancer; health; tumor microenvironment; spatial biology; cancer diagnosis; cancer drug discovery; Omics
Cancer Patient Cognitive Disorders: Causes, Prevention and Management submission deadline 31 Dec 2026 | Viewed by 279 | Submission Open
Keywords: delirium; brain health; cognitive impairment; cancer; etiology; risk stratification; screening tool; biomarkers; postoperative delirium; pain management; delirium prevention; management; outcomes
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Cancer Cell Communications, Metastasis and Survival in the Host Microenvironment—2nd Edition
edited by and
submission deadline 31 Dec 2026 | Viewed by 77 | Submission Open
Keywords: cancer cells; cancer cell-derived cytokines; host microenvironment; metastasis; gene alteration; signaling pathways; host cells
(This special issue belongs to the Section Tumor Microenvironment)
Tumor Microenvironment: Cellular Dynamics, Molecular Players, and Mechanisms of Therapy Resistance
edited by , Angeliki Ditsiou and
submission deadline 31 Dec 2026 | Viewed by 45 | Submission Open
Keywords: tumor microenvironment (TME); cellular interactions; molecular mechanisms; resistance mechanisms; signaling pathways; translational cancer therapy
(This special issue belongs to the Section Tumor Microenvironment)
Advances in Cancer Survival Analysis
edited by , Jianguang Ji and
submission deadline 31 Dec 2026 | Viewed by 37 | Submission Open
Keywords: cancer burden; cancer survival; epidemiology; survival analysis methodology; cancer screening; cancer control; cancer prognosis; cancer data mining
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Cutaneous Lymphomas: Present and Future
edited by
submission deadline 31 Dec 2026 | Viewed by 4 | Submission Open
Keywords: cutaneous lymphoma; T-cell lymphoma; B-cell lymphoma; mycosis fungoides; Sé zary syndrome; tumor microenvironment
Resistance in Lung Cancer
edited by Mohamed Gadelkarim
submission deadline 15 Mar 2027 | Viewed by 22 | Submission Open
Keywords: lung cancer; SCLC; NSCLC; drug resistance; genetic mutations; tumor microenvironment; EMT; biomarkers; targeted therapy; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
New Statistical and Machine Learning Methods for Cancer Research
edited by Anjishnu Banerjee
submission deadline 20 May 2027 | Viewed by 60 | Submission Open
Keywords: statistical methods; machine learning; “Omics” research; adaptive clinical trials; drug development; personalized cancer therapies
(This special issue belongs to the Section Cancer Informatics and Big Data)
Cancer Causes and Control submission deadline 1 Dec 2027 | 4 articles | Viewed by 10549 | Submission Open
Keywords: cancer burden; risk factors for cancer; primary cancer prevention; secondary cancer prevention; tertiary cancer prevention; quality of life for people who have cancer; population-based cancer registry
(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)
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