Special Issues

Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Perspectives in Hepato-Biliary and Pancreatic Cancer
edited by Tudor Mocan and Emil-Ioan Moiș
submission deadline 31 Jan 2026 | Viewed by 37 | Submission Open
Keywords: HCC; cholangiocarcinoma; surgery; biliary drainage; pancreatic cancer; combination therapies
(This special issue belongs to the Section Cancer Therapy)
Breast Cancer and Stem Cells
edited by Leandro Marcelo Martinez
submission deadline 31 Jan 2026 | Viewed by 37 | Submission Open
Keywords: breast cancer; cancer stem cells; tumor microenvironment; metastasis; therapeutic strategies; in vitro models
(This special issue belongs to the Section Molecular Cancer Biology)
Diagnosis and Biomarkers for Hematologic Malignancies submission deadline 31 Jan 2026 | Viewed by 35 | Submission Open
Keywords: hematologic malignancies; diagnosis; biomarkers
(This special issue belongs to the Section Cancer Biomarkers)
Curative Therapies for Non-Small and Small Cell Lung Cancers
edited by John Michael Varlotto
submission deadline 31 Jan 2026 | Viewed by 29 | Submission Open
Keywords: radiotherapy; surgery; early stage NSCLC; oligometastases; immunotherapy; small-cell lung cancer
(This special issue belongs to the Section Cancer Therapy)
Immune Profiling in Gastrointestinal Cancers: Implications for Precision Immunotherapy
edited by
submission deadline 31 Jan 2026 | Viewed by 28 | Submission Open
Keywords: gastrointestinal cancer; immune profiling; immunocompetent cells; personalized immunotherapy; biomarkers; precision medicine; tumor microenvironment; tumor-infiltrating lymphocytes; immune checkpoint inhibitors; microbiota– immunity interactions; single-cell analysis; spatial transcriptomics
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Laryngeal Cancer: Diagnostic Workup, Treatment, and Complications
edited by Francesco Mattioli
submission deadline 31 Jan 2026 | Viewed by 23 | Submission Open
Keywords: laryngeal cancers; diagnosis; laryngeal surgery; transoral laser microsurgery; transoral robotic surgery
(This special issue belongs to the Section Clinical Research of Cancer)
Conversion Surgery for Initially Unresectable, Locally Advanced, Metastatic or Recurrent Gastrointestinal Cancers
edited by
submission deadline 31 Jan 2026 | Viewed by 18 | Submission Open
Keywords: conversion surgery; locally advanced disease; metastatic disease; chemotherapy; radiotherapy; immunotherapy; heptobiliary-pancreatic cancers; gastrointestinal tract cancers
(This special issue belongs to the Section Clinical Research of Cancer)
Updates on Imaging of Common Urogenital Neoplasms 2nd Edition
edited by Athina C Tsili
submission deadline 31 Jan 2026 | Viewed by 13 | Submission Open
Keywords: urogenital neoplasms; renal cell carcinoma; prostatic neoplasms; urinary bladder neoplasms; testicular neoplasms; uterine neoplasms; ovarian neoplasms; ultrasonography; computed tomography; magnetic resonance imaging
(This special issue belongs to the Section Methods and Technologies Development)
Novel Approaches in the Management of Gynecological Cancers submission deadline 31 Jan 2026 | Viewed by 7 | Submission Open
Keywords: gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer; vulvar cancer; surgical management; clinical management
(This special issue belongs to the Section Cancer Therapy)
Therapy for HER2 Breast Cancer
edited by and Sandra M. Swain
submission deadline 1 Feb 2026 | Viewed by 3 | Submission Open
Keywords: antibody– drug conjugate; trastuzumab; pertuzumab; tyrosine kinase inhibitor; trastuzumab deruxtecan
(This special issue belongs to the Section Cancer Therapy)
Transforming Liver Cancer Care: From Molecular Understanding to Novel Therapeutic Strategies
edited by
submission deadline 10 Feb 2026 | Viewed by 134 | Submission Open
Keywords: liver cancer; molecular research; biomarkers; targeted therapy; translational research
(This special issue belongs to the Section Tumor Microenvironment)
Exercise and Cancer Treatment: The Clinical Application of Exercise Oncology
edited by Helena Batatinha
submission deadline 10 Feb 2026 | Viewed by 70 | Submission Open
Keywords: exercise oncology; cancer therapy; immunotherapy; patient outcomes
(This special issue belongs to the Section Clinical Research of Cancer)
New Insights into Cancer Radiotherapy submission deadline 10 Feb 2026 | Viewed by 65 | Submission Open
Keywords: radiotherapy; X-rays; gamma rays; external beam radiation therapy; brachytherapy; palliative care; intensity-modulated radiotherapy (IMRT); stereotactic body radiotherapy (SBRT); proton therapy
(This special issue belongs to the Section Cancer Therapy)
Recent Developments in the Field of Radiotherapy Treatment for Lung Cancer
edited by Ioannis C. Maroulis
submission deadline 10 Feb 2026 | Viewed by 17 | Submission Open
Keywords: lung cancer; radiotherapy; non-small-cell lung cancer (NSCLC)
(This special issue belongs to the Section Cancer Therapy)
Metronomic Chemotherapy in Female Cancers
edited by
submission deadline 14 Feb 2026 | 1 articles | Viewed by 700 | Submission Open
Keywords: metronomic chemotherapy; female cancers; anti-tumor mechanisms; clinical trials and outcomes; combination therapies
(This special issue belongs to the Section Cancer Therapy)
Advances in Surgical Treatment of Gynecological Cancers
edited by , Joanna P. Kacperczyk-Bartnik and
submission deadline 14 Feb 2026 | Viewed by 151 | Submission Open
Keywords: gynecological oncology; image-guided surgery; lymphadenectomy; minimally invasive surgery; ovarian cancer surgery; patient outcomes; perioperative care; precision surgery; radical hysterectomy; robotic-assisted surgery; surgical oncology
(This special issue belongs to the Section Cancer Therapy)
New Strategies in Diagnosis and Treatments for Brain Tumors: 2nd Edition
edited by Sven Rainer Kantelhardt
submission deadline 15 Feb 2026 | 3 articles | Viewed by 9649 | Submission Open
Keywords: glioma; brain tumor; molecular guided therapy; personal medicine; radiomics; digital analysis; artificial intelligence; intraoperative imaging; surgical resection
(This special issue belongs to the Section Cancer Therapy)
New and Emerging Strategies for Targeting Genomic Instability and Overcoming Drug Resistance in Lung Cancer
edited by Kelsie L. Thu
submission deadline 15 Feb 2026 | 5 articles | Viewed by 8333 | Submission Open
Keywords: lung cancer; genomic instability; drug resistance; treatment strategy; targeted therapy
(This special issue belongs to the Section Cancer Therapy)
Neoadjuvant Therapy in Hepatopancreatobiliary Malignancies: Current Trends and Future Directions submission deadline 15 Feb 2026 | 1 articles | Viewed by 840 | Submission Open
Keywords: neoadjuvant therapy; hepatopancreatobiliary malignancies; hepatocellular carcinoma; pancreatic cancer; cholangiocarcinoma; chemotherapy; radiotherapy; immunotherapy; targeted therapies; personalized treatment
(This special issue belongs to the Section Cancer Therapy)
Advances in Precision Medicine: Targeting Known and Emerging Oncogenic Targets in Lung Cancer (2nd Edition)
edited by
submission deadline 15 Feb 2026 | Viewed by 56 | Submission Open
Keywords: precision oncology; lung cancer; oncogenic target; targeted therapy; biomarker; diagnosis
(This special issue belongs to the Section Molecular Cancer Biology)
Genetic Changes in CNS Neoplasms
edited by Kimberly Bojanowski Hoang
submission deadline 15 Feb 2026 | Viewed by 40 | Submission Open
Keywords: primary brain tumor; secondary brain tumor; metastasis; glioma; genetics; genomics; CNS; neoplasms
(This special issue belongs to the Section Cancer Biomarkers)
Diagnosis, Treatment and Prevention of Gastrointestinal Cancer (2nd Edition)
edited by and Min Gi
submission deadline 18 Feb 2026 | 1 articles | Viewed by 732 | Submission Open
Keywords: cancer; screening; diagnosis; anti-cancer; drugs; mechanisms of carcinogenesis; chemopreventive agents
(This special issue belongs to the Section Cancer Therapy)
Gaps in Cancer Cachexia Research
edited by Jose M. Garcia and
submission deadline 20 Feb 2026 | 3 articles | Viewed by 7125 | Submission Open
Keywords: cancer cachexia; physical function; innovative models; rehabilitation; patient-reported outcomes; gender; aging; skeletal muscle; brain; adipose tissue
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Chronic Intestinal Inflammation and Cancers (2nd Edition)
edited by Livia Biancone and David Laharie
submission deadline 20 Feb 2026 | 1 articles | Viewed by 1256 | Submission Open
Keywords: colorectal cancer; chronic inflammation; inflammatory bowel disease; inflammation-associated dysplasia; outcomes; cancer molecular pathways
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Fibroblasts as Playmakers of Cancer Progression: Current Knowledge and Future Perspectives (2nd Edition)
edited by
submission deadline 20 Feb 2026 | Viewed by 153 | Submission Open
Keywords: tumor microenvironment; reactive stroma; fibroblasts; cancer progression; heterotypic interactions between cancer cells and fibroblasts; reactive stroma-targeted therapy
(This special issue belongs to the Section Molecular Cancer Biology)
Molecular Tumor Boards: Promise and Limitations for Personalized Cancer Therapy: 2nd Edition
edited by
submission deadline 20 Feb 2026 | Viewed by 91 | Submission Open
Keywords: targeted therapy; drug repositioning; biomarkers; basket trials; precision oncology; personalized medicine
(This special issue belongs to the Section Molecular Cancer Biology)
Multiple Myeloma: Recent Advances in Diagnosis, Analysis and Therapeutic Management: 2nd Edition submission deadline 20 Feb 2026 | Viewed by 68 | Submission Open
Keywords: multiple myeloma (MM); hematologic malignancies; next-generation sequencing; heterogeneous disease; tumor heterogeneity; genomic landscape; outcomes; novel treatments; clinical trial
(This special issue belongs to the Section Cancer Therapy)
Quality of Life and Side Effects Management in Cancer Treatment (3rd Edition)
edited by
submission deadline 20 Feb 2026 | Viewed by 55 | Submission Open
Keywords: cancer treatment adverse events; quality of life in cancer patients; chemotherapy adverse events; target therapy adverse events; immunotherapy adverse events; hormonotherapy adverse events; chemotherapy-induced nausea and vomiting; cancer pain
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
Advanced Surgical Modalities in Breast Cancer Treatment
edited by Jan Žatecký
submission deadline 20 Feb 2026 | Viewed by 39 | Submission Open
Keywords: breast cancer surgery; breast cancer localization; breast conserving surgery; mastectomy; oncoplastic surgery; axillary lymph node staging; sentinel lymph node biopsy; targeted axillary dissection
(This special issue belongs to the Section Clinical Research of Cancer)
Radiation Therapy for Modern Management of Bone Metastases (2nd Edition)
edited by
submission deadline 25 Feb 2026 | Viewed by 57 | Submission Open
Keywords: radiotherapy; palliative care; steretactic radiotherapy; SBRT; immunotherapy; chemotherapy; oligometastases
(This special issue belongs to the Section Cancer Therapy)
Harnessing the Gut Microbiome to Improve Colorectal Cancer Outcomes
edited by Carole S. Richard
submission deadline 25 Feb 2026 | Viewed by 14 | Submission Open
Keywords: colorectal cancer (CRC); gut microbiome; screening; CRC cells; the gut microenvironment; oncological outcomes
(This special issue belongs to the Section Infectious Agents and Cancer)
Minimal Residual Disease in Solid Tumors: Emerging Technologies and Clinical Applications
edited by , and Aristeidis Boukouris
submission deadline 25 Feb 2026 | Viewed by 2 | Submission Open
Keywords: minimal residual disease (MRD); solid tumors; circulating tumor DNA (ctDNA); liquid biopsy; tumor-informed assays; precision oncology
(This special issue belongs to the Section Cancer Biomarkers)
Advances in the Treatment of Gastrointestinal (GI) Cancers
edited by
submission deadline 27 Feb 2026 | Viewed by 35 | Submission Open
Keywords: gastrointestinal cancers; targeted therapy; immunotherapy; precision oncology; biomarkers; molecular mechanisms; tumor microenvironment; resistance to therapy; translational research; clinical trials
(This special issue belongs to the Section Cancer Therapy)
Clinical and Translational Updates in Renal Cell Carcinoma (2nd Edition)
edited by
submission deadline 27 Feb 2026 | Viewed by 28 | Submission Open
Keywords: renal cell carcinoma; RCC; machine cearning; clinical; translational developments
(This special issue belongs to the Section Clinical Research of Cancer)
Improving Surgical Care for Patients with Hepatobiliary and Pancreatic Cancers
edited by Christopher B. Nahm and Kai M. Brown
submission deadline 28 Feb 2026 | 2 articles | Viewed by 5787 | Submission Open
Keywords: hepatobiliary; pancreatic; surgery; biomarkers; prognosis; treatment strategy
(This special issue belongs to the Section Cancer Therapy)
Advances in Bladder Preservation Approaches for Bladder Cancer (2nd Edition)
edited by and Todd A. Yezefski
submission deadline 28 Feb 2026 | 3 articles | Viewed by 5465 | Submission Open
Keywords: bladder cancer; bladder preservation; trimodality therapy; chemoradiation; immunotherapy; intravesical therapy; BCG refractory or unresponsive
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Advances in Oncological Imaging (2nd Edition) submission deadline 28 Feb 2026 | 1 articles | Viewed by 2790 | Submission Open
Keywords: oncological imaging; radiomics; deep learning; machine learning; image reconstruction; artificial intelligence; outcome prediction; oncological treatment planning; advanced imaging; personalized medicine
(This special issue belongs to the Section Methods and Technologies Development)
Navigating the Landscape of Female Cancers: Recent Discoveries and Treatment Trends
edited by and Giacomo Barchiesi
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1321 | Submission Open
Keywords: female malignancies; breast cancer; gynecological cancer; ovarian cancer; endometrial cancer; cervical cancer
(This special issue belongs to the Section Cancer Therapy)
Innovative and Personalized Approaches to Improve Patient Outcomes in Gynecological Oncology
edited by Anke Smits and James Dilley
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1160 | Submission Open
Keywords: gynecological cancer; lifestyle; prehabilitation; rehabilitation; survival; quality of life
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
New Insights into General, Functional and Oncologic Urology
edited by Kajetan Juszczak and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 479 | Submission Open
Keywords: basic science; experimental models; urological cancer; management innovations; multidisciplinary approaches; treatment outcomes
(This special issue belongs to the Section Clinical Research of Cancer)
Precision Health Care and Interventions in Hereditary Breast and Ovarian Cancer and Lynch Syndrome (2nd Edition)
edited by
submission deadline 28 Feb 2026 | Viewed by 470 | Submission Open
Keywords: breast cancer; ovarian Cancer; lynch Syndrome; precision healthcare
(This special issue belongs to the Section Cancer Epidemiology and Prevention)
Personalized Radiotherapy in Cancer Care (2nd Edition)
edited by and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 466 | Submission Open
Keywords: predictive biomarkers; treatment-related toxicity; radiation treatments; radiation dose and volume; personalized radiation therapy
(This special issue belongs to the Section Methods and Technologies Development)
Predictive and Prognostic Biomarkers for Response to Neoadjuvant Chemotherapy for Breast Cancer
edited by Tarek M. A. Abdel-Fatah
submission deadline 28 Feb 2026 | 1 articles | Viewed by 371 | Submission Open
Keywords: breast cancer; predictive and prognostic biomarkers; neoadjuvant chemotherapy; HER2-targeting agents; complete pathological response
(This special issue belongs to the Section Cancer Therapy)
Immunoediting in Cancer Therapies
edited by Vijay Kumar
submission deadline 28 Feb 2026 | Viewed by 358 | Submission Open
Keywords: cancer; cancer immunology; immunosurveillance; immunoediting; immunotherapy; immunomodulation; immunometabolism
(This special issue belongs to the Section Cancer Immunology and Immunotherapy)
Advances in the Diagnosis and Treatment of Genitourinary Cancers (2nd Edition)
edited by Piotr Radziszewski and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 340 | Submission Open
Keywords: genitourinary cancer; point-of-care diagnostics; personalized treatment; immunotherapy
(This special issue belongs to the Section Cancer Therapy)
Perioperative Care in Gynecologic Oncology: 2nd Edition
edited by Nikolaos Thomakos and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 285 | Submission Open
Keywords: enhanced recovery; ERAS; immunonutrition; prehabilitation; gynecologic oncology; minimally invasive surgery
(This special issue belongs to the Section Cancer Survivorship and Quality of Life)
MYC Oncogene in Cancer: Cancer Cell Intrinsic and Immune Inhibitory Functions
edited by Wadie Mahauad Fernandez and Konstantinos V. Floros
submission deadline 28 Feb 2026 | Viewed by 137 | Submission Open
Keywords: MYC oncogene; molecular oncology; immuno-oncology; tumor microenvironment
(This special issue belongs to the Section Molecular Cancer Biology)
MRI and Artificial Intelligence in Oncology: Current Research and Future Directions submission deadline 28 Feb 2026 | 1 articles | Viewed by 135 | Submission Open
Keywords: MRI; AI; radiology; oncology; clinical trials
(This special issue belongs to the Section Methods and Technologies Development)
Advances in Choroidal Melanoma: From Treatment to Prognosis
edited by
submission deadline 28 Feb 2026 | Viewed by 125 | Submission Open
Keywords: melanoma; uveal; choroid; treatments; target; immunotherapy; genetics
(This special issue belongs to the Section Molecular Cancer Biology)
Image-Assisted High-Precision Radiation Oncology
edited by He C. Wang
submission deadline 28 Feb 2026 | Viewed by 114 | Submission Open
Keywords: medical imaging; radiation oncology; artificial intelligence; radiomics; adaptation; tumor response
(This special issue belongs to the Section Cancer Therapy)
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