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Cancers
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Advanced Ovarian Cancer (2nd Edition)
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Advanced Ovarian Cancer (2nd Edition)

A special issue of Cancers (ISSN 2072-6694). This special issue belongs to the section "Cancer Therapy".

Deadline for manuscript submissions: 31 December 2025 | Viewed by 1266

Special Issue Editor

Prof. Sheng-Mou Hsiao

E-Mail Website
Guest Editor
1. Department of Obstetrics and Gynecology, Far Eastern Memorial Hospital, Banqiao, New Taipei 220216, Taiwan
2. Graduate School of Biotechnology and Bioengineering, Yuan Ze University, Taoyuan 320315, Taiwan
3. Department of Obstetrics and Gynecology, National Taiwan University College of Medicine and Hospital, Taipei 100226, Taiwan
Interests: gynecologic cancer; intraperitoneal chemotherapy; sentinel lymph node mapping; hyperthermic intraperitoneal chemotherapy; intraoperative radiotherapy
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

In the past decade, there has been significant progress in the evaluation and treatment of advanced ovarian cancer in addition to a combination of debulking surgery and systemic chemotherapy, such as homologous recombination deficiency evaluation, hyperthermic intraperitoneal chemotherapy, anti-vascular endothelial growth factor therapy, poly ADP-ribose polymerase inhibitor, and even immune checkpoint inhibitor. However, the prognosis of a significant portion of patients with advanced ovarian cancer remains poor. Thus, intensive study is needed to determine the optimal evaluation and treatment strategies.

We welcome submissions in advanced or recurrent ovarian cancer that cover any relevant topic in the areas of risk assessment and stratification, and medical and surgical management strategies.

Prof. Sheng-Mou Hsiao
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cancers is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • advanced ovarian cancer
  • medical treatment
  • surgical treatment
  • hyperthermic intraperitoneal chemotherapy
  • intraperitoneal chemotherapy

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Published Papers (2 papers)

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Research

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14 pages, 922 KB  
Article
Predictors of Extended Intensive Care Unit Utilization After Ovarian Cancer Surgery
by Vasilis Theodoulidis, Kalliopi Kissoudi, Kimonas Chatzistamatiou, Panagiotis Tzitzis, Dimitris Zouzoulas, Iakovos Theodoulidis, Christos Anthoulakis, Freideriki Sifaki, Theodoros Moysiadis, Eleni Koraki, Grigoris Grimbizis and Dimitris Tsolakidis
Cancers 2025, 17(19), 3203; https://doi.org/10.3390/cancers17193203 - 1 Oct 2025
Viewed by 347
Abstract
Background: Patients with ovarian cancer often require intensive care unit (ICU) admission after surgery due to the complexity of the operation and the higher risk of complications. However, not all patients require a prolonged stay in the ICU. To identify factors that may [...] Read more.
Background: Patients with ovarian cancer often require intensive care unit (ICU) admission after surgery due to the complexity of the operation and the higher risk of complications. However, not all patients require a prolonged stay in the ICU. To identify factors that may predict extended stay in the ICU following surgery for ovarian cancer. Methods: A retrospective review was conducted of patients who underwent surgery for ovarian cancer and were admitted to the ICU at a single tertiary hospital center between January 2004 and December 2023. Patient demographics, clinical characteristics, and perioperative variables were analyzed. Results: Of the 74 patients included, 36.5% had an ICU stay of at least 48 h. Factors associated with prolonged ICU stay included higher Body Mass Index (BMI) and time of surgery duration. In contrast, a greater body temperature at the end of the operation was linked to a decrease in the length of ICU stay. Conclusions: These findings provide valuable insights for preoperative counseling and resource allocation, enhancing postoperative care for ovarian cancer patients. Additional research is required to confirm these data and investigate any other factors that may predict extended stay in the ICU. Full article
(This article belongs to the Special Issue Advanced Ovarian Cancer (2nd Edition))
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Review

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22 pages, 4027 KB  
Review
The Imaging of Primary Fallopian Tube Carcinoma: A Literature Review
by Giulia Iacobellis, Alessia Leggio, Cecilia Salzillo, Amalia Imparato and Andrea Marzullo
Cancers 2025, 17(18), 2985; https://doi.org/10.3390/cancers17182985 - 12 Sep 2025
Viewed by 752
Abstract
Primary Fallopian tube carcinomas (PFTCs) are rare malignancies that are often misclassified as ovarian cancers due to overlapping clinical and pathological features. This frequent misdiagnosis contributes to the under-recognition of PFTCs, which account for a larger proportion of pelvic malignancies than historically reported. [...] Read more.
Primary Fallopian tube carcinomas (PFTCs) are rare malignancies that are often misclassified as ovarian cancers due to overlapping clinical and pathological features. This frequent misdiagnosis contributes to the under-recognition of PFTCs, which account for a larger proportion of pelvic malignancies than historically reported. The central aim of this literature review is to highlight the critical importance of and methods for achieving an early diagnosis of Fallopian tube cancer, to improve patient outcomes. We classify benign and malignant fallopian tube neoplasms and evaluate the essential role of clinical evaluation and advanced imaging techniques, considering especially ultrasound, MRI, and PET-CT, in achieving an accurate and timely diagnosis. While histopathology remains the gold standard, imaging is pivotal for differentiating benign from malignant tubal lesions. This review details clinical manifestations, diagnostic pitfalls, and the necessity of a multidisciplinary approach to management. We conclude that advancing early detection through refined diagnostic criteria is essential to guiding effective, patient-specific therapeutic interventions. Full article
(This article belongs to the Special Issue Advanced Ovarian Cancer (2nd Edition))
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