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Cancers publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Ovarian Cancer Biomarkers, Diagnostic, and Therapeutic Technologies 2nd Edition

edited by

Andrew Stephens

submission deadline 31 Dec 2025 | 5 articles | Viewed by 5212 | Submission Open

Keywords: diagnostic; prognostic; theranostic; therapy; metastasis; biomarker; regression; chemoresistance; invasion

(This special issue belongs to the Section Cancer Biomarkers)

Overcoming Chemoresistance in Cancer: Identifying Biomarkers and Novel Targets

edited by

Annapina Russo

Giulia Russo

and

Annalisa Pecoraro

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4998 | Submission Open

Keywords: cancer treatment; chemoresistance; tumor microenvironment; cancer signaling pathways; targeted therapy; personalized anti-cancer therapies; biomarker; anti-cancer drug response prediction

(This special issue belongs to the Section Cancer Therapy)

The Applications of Artificial Intelligence in Gastroenterology

edited by

Marcello F. Maida

Ciro Celsa

and Louis H. S. Lau

submission deadline 31 Dec 2025 | 3 articles | Viewed by 4956 | Submission Open

Keywords: artificial intelligence; gastroenterology; endoscopy; inflammatory bowel diseases

(This special issue belongs to the Section Cancer Therapy)

Advances in Surgical Treatment of Urinary Tumors

edited by Pierre I. Karakiewicz and

Simone Morra

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4784 | Submission Open

Keywords: bladder cancer; prostate cancer; kidney cancer; quality of life; urologic oncology

(This special issue belongs to the Section Cancer Therapy)

Advancements in Head and Neck Cancer Surgery

edited by

Carlos M. Chiesa-Estomba

submission deadline 31 Dec 2025 | 4 articles | Viewed by 4746 | Submission Open

Keywords: minimal invasive; transoral; robotic; reconstructive; 3D printing; targeting therapies; imaging

(This special issue belongs to the Section Clinical Research of Cancer)

Celebrating the 2024 Nobel Prize in Chemistry: Advancements in Artificial Intelligence and Machine Learning for Cancer Therapeutics

edited by

Athanasios G. Papavassiliou

and

Le Zhang

submission deadline 31 Dec 2025 | 2 articles | Viewed by 4123 | Submission Open

Keywords: AI in cancer therapeutics; machine learning for drug discovery; protein structure prediction; personalized cancer treatment; clinical AI applications

(This special issue belongs to the Section Cancer Therapy)

Clear Cell Renal Cell Carcinoma 2024–2025

edited by

José I. López

and

Claudia Manini

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3798 | Submission Open

Keywords: clear cell renal cell carcinoma; pathology; diagnosis; hypoxia; intratumor heterogeneity; immune checkpoint blockage antiangiogenic therapy

(This special issue belongs to the Section Cancer Pathophysiology)

Robotic Surgery in Colorectal Cancer

edited by James Chi Yong Ngu

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3766 | Submission Open

Keywords: robotic surgery; colorectal cancer; minimally invasive surgery; therapeutic endoscopy; laparoscopy

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Radiation Therapy for Head and Neck Cancer

edited by

Vassilis Kouloulias

submission deadline 31 Dec 2025 | 4 articles | Viewed by 3576 | Submission Open

Keywords: adaptive radiotherapy ; hyper- and hypo-fractionated radiotherapy ; artificial intelligence in radiotherapy for head and neck cancer ; quality assurance and set-up errors associated with IMRT; VMAT; IGRT; and SGRT techniques ; protons and heavy ions for radiotherapy ; re-irradiation ; nanoparticles plus radiotherapy ; hyperthermia plus radiotherapy ; radiotherapy plus immunotherapy ; the de-escalation of radiation therapy

(This special issue belongs to the Section Cancer Therapy)

Feature Papers in Section "Tumor Microenvironment"

edited by

Sanjay Gupta

submission deadline 31 Dec 2025 | 3 articles | Viewed by 3555 | Submission Open

Keywords: tumor microenvironment; cancer progression; interactions; therapeutic targeting; immune response

(This special issue belongs to the Section Tumor Microenvironment)

Enhancing Cancer Treatments through Fluorescence-Guided Surgery

edited by Ibrahim Khot and Yazan Sulaiman Khaled

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3280 | Submission Open

Keywords: fluorescence-guided resection; fluorescent imaging; cancer surgery; tumour targeting; intraoperative staging; oncological fluorescence; precision medicine

(This special issue belongs to the Section Methods and Technologies Development)

Artificial Intelligence-Assisted Radiomics in Cancer

edited by

Seong K. Mun

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3219 | Submission Open

Keywords: radiomics; learning tools; data normalization; segmentation; artificial intelligence; quantitative imaging; multi-dimensional feature analysis; statistical models; precision medicine

(This special issue belongs to the Section Methods and Technologies Development)

Physiotherapy in Advanced Cancer and Palliative Care

edited by Nele Adriaenssens

submission deadline 31 Dec 2025 | 2 articles | Viewed by 3059 | Submission Open

Keywords: advanced cancer; palliative care; palliative needs; physiotherapy; physical therapy modalities; quality of life; physical autonomy

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Advances in Spine Oncology: Research and Clinical Studies

edited by Oluwaseun O. Akinduro

submission deadline 31 Dec 2025 | 4 articles | Viewed by 2812 | Submission Open

Keywords: metastatic spine cancer; targeted therapy; stereotactic body radiotherapy; proton radiotherapy; chordoma; chondrosarcoma; spondylectomy

(This special issue belongs to the Section Clinical Research of Cancer)

Application of Artificial Intelligence-Based Approaches in Cancer Diagnosis, Treatment and Prognosis

edited by

Wei Wu

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2714 | Submission Open

Keywords: cancer genomics; artificial intelligence; machine learning; deep learning; tumor microenvironment; graph-based convolutional neural network; computational cancer biology

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Clinical Trials: Outcome, Innovations, Challenges, and Ethical Practice in Cancer Research 2024–2025

edited by

Naoto T. Ueno

and David R. Gandara

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2614 | Submission Open

Keywords: phase I; phase II; phase III; phase IV; clinical trials; features; design; implementation; outcomes

(This special issue belongs to the Section Clinical Research of Cancer)

Hereditary and Familial Colorectal Cancer

edited by Bryson W. Katona and Peter P. Stanich

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2506 | Submission Open

Keywords: hereditary colorectal cancer; familial colorectal cancer; genetic predisposition; polyposis; Lynch syndrome; familial adenomatous polyposis (FAP); MUTYH-associated polyposis (MAP); genetic testing

(This special issue belongs to the Section Cancer Pathophysiology)

Immunotherapy in Non-Small Cell Lung Cancers

edited by Marco Russano

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2415 | Submission Open

Keywords: non-small cell lung cancer; immune checkpoint inhibitors; PD-1/PD-L1 blockade; immunotherapy; biomarkers

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Recent Advances in Non-muscle Invasive Bladder Cancer

edited by Paul L. Crispen

submission deadline 31 Dec 2025 | 2 articles | Viewed by 2409 | Submission Open

Keywords: non-muscle invasive bladder cancer; adjuvant therapy; surveillance; BCG refractory; intravesical therapy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Chemotherapy and Immunotherapy of Lung Cancer

edited by

Sonia Vallet

and Klaus Hackner

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2284 | Submission Open

Keywords: immune checkpoint inhibitors; immunotherapy; lung cancer; programmed-death ligand; chemoimmunotherapy; non-small-cell lung cancer; small-cell lung cancer

(This special issue belongs to the Section Cancer Therapy)

Advances in the Use of PET/CT and MRI in Prostate Cancer

edited by Carmelo Caldarella

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2226 | Submission Open

Keywords: PET/CT; MRI; prostate cancer; radiomic; receptor-targeted radiopharmaceuticals

(This special issue belongs to the Section Methods and Technologies Development)

Innovative Biomarkers and Imaging Techniques for the Early Detection and Risk Stratification of Urological Tumours

edited by

Magdalena Görtz

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2190 | Submission Open

Keywords: urological tumours; novel biomarkers; advanced imaging techniques; early detection; risk stratification; molecular diagnostics; multimodal data integration; personalized treatment

(This special issue belongs to the Section Cancer Epidemiology and Prevention)

New Insights into Kidney Disease Development and Therapy Strategies

edited by

José I. López

and

Claudia Manini

submission deadline 31 Dec 2025 | 1 articles | Viewed by 2016 | Submission Open

(This special issue belongs to the Section Cancer Therapy)

New Perspectives in the Management of Central Nervous System (CNS) Tumors

edited by

Alessia Pellerino

, Francesco Bruno and

Teresa Somma

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1758 | Submission Open

Keywords: gliomas; brain metastases; leptomeningeal metastases; liquid biopsy; neuroradiological tools; brain surgery; targeted therapy; immunotherapy; clinical trials; molecular factors

(This special issue belongs to the Section Cancer Therapy)

Feature Papers in Section “Cancer Informatics and Big Data”

edited by

Jason Roszik

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1725 | Submission Open

Keywords: artificial intelligence; deep learning; next-generation sequencing; precision medicine and clinical decision-making; single-cell data analytics

(This special issue belongs to the Section Cancer Informatics and Big Data)

Fertility Preservation in Gynecological Cancer

edited by

Giuseppe Gullo

and

Luigi Della Corte

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1719 | Submission Open

Keywords: gynecological cancer; fertility preservation; surgery treatments; fertility sparing; psychological implication

(This special issue belongs to the Section Methods and Technologies Development)

Advances in Breast and Gynecologic Cancer Pathology: Molecular Insights and Therapeutic Implications

edited by

Hisham Bahmad

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1684 | Submission Open

Keywords: breast cancer; gynecologic malignancies; diagnostic pathology; molecular biomarkers; histopathology; cytopathology; prognostic markers; targeted therapy

(This special issue belongs to the Section Cancer Pathophysiology)

Precision Oncology for Rare Skin Cancers

edited by Gino K. In and Aparna Nallagangula

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1548 | Submission Open

Keywords: rare skin cancers; melanoma; cutaneous squamous cell carcinoma; basal cell carcinoma; Merkel cell carcinoma; sebaceous carcinoma; adnexal/sweat gland carcinoma; dermatofibrosarcoma protuberans; extramammary Paget’ s disease; cutaneous sarcomas

(This special issue belongs to the Section Molecular Cancer Biology)

New Insights in the Management of Resectable Esophageal Malignancy

edited by

Tania Triantafyllou

and Dimitrios A. Theodorou

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1456 | Submission Open

Keywords: esophageal cancer; perioperative chemotherapy; radiotherapy; immunotherapy; radical surgical resection

(This special issue belongs to the Section Methods and Technologies Development)

The Advance of Biomarker-Driven Targeted Therapies in Cancer

edited by

Tianshun Zhang

, Qiushi Wang and Ann Bode

submission deadline 31 Dec 2025 | 2 articles | Viewed by 1272 | Submission Open

Keywords: biomarkers; targeted therapies; precision medicine; cancer treatment; molecular profiling; personalized medicine; genomic alterations; therapeutic interventions; tumor microenvironment; immune therapy

(This special issue belongs to the Section Cancer Therapy)

Perspectives on the Efficacy and Biomarkers of Immunotherapy and Targeted Therapy for Patients with Colorectal Cancer

edited by

Ibrahim Halil Sahin

submission deadline 31 Dec 2025 | 1 articles | Viewed by 1010 | Submission Open

Keywords: colorectal cancer; precision medicine; targeted therapeutics; immunotherapy; KRAS; BRAF; HER2; biomarkers

(This special issue belongs to the Section Cancer Therapy)

Advances in the Management of Oropharyngeal Cancer: Navigating the HPV-Associated Landscape

edited by Jon Mallen-St Clair

submission deadline 31 Dec 2025 | 1 articles | Viewed by 885 | Submission Open

Keywords: oropharyngeal cancer; human papillomavirus; clinical trials; transoral robotic surgery; epidemiology; HPV-related oropharyngeal cancer

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Advances in Pancreatic Ductal Adenocarcinoma Diagnosis and Treatment 2nd Edition

edited by

Andrzej Deptała

submission deadline 31 Dec 2025 | 2 articles | Viewed by 849 | Submission Open

Keywords: pancreatic cancer; pancreatic ductal adenocarcinoma; genetic changes; genomics; surgical resection; radiotherapy; radiochemotherapy; chemotherapy; targeted therapy; immunotherapy; resectable tumor; borderline resectable tumor; metastatic disease; nutritional treatment; quality of life

(This special issue belongs to the Section Cancer Therapy)

Advances in Ovarian Cancer Treatment: Past, Present and Future

edited by Dimitrios Tsolakidis and Dimitrios Zouzoulas

submission deadline 31 Dec 2025 | 1 articles | Viewed by 820 | Submission Open

Keywords: ovarian cancer; cytoreductive surgery; HIPEC; chemotherapy; immunotherapy

(This special issue belongs to the Section Cancer Therapy)

Radiosurgery for Brain Tumors

edited by Anna Petoukhova

submission deadline 31 Dec 2025 | 1 articles | Viewed by 724 | Submission Open

Keywords: radiosurgery with photons and protons; stereotactic radiosurgery (SRS); brain tumors; gliomas; meningioma; pituitary adenoma; magnetic resonance imaging (MRI); magnetic resonance linac (MRL)

(This special issue belongs to the Section Cancer Therapy)

Long-Term Cancer Survivors: Rehabilitation and Quality of Life

edited by

Juan Rodríguez-Mansilla

Blanca Gonzalez-Sanchez

and

María Jiménez-Palomares

submission deadline 31 Dec 2025 | 1 articles | Viewed by 662 | Submission Open

Keywords: long term; cancer survivors; quality of life; rehabilitation; physical activity; cognition; non-pharmacological therapies

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Radioimmunotherapy, Neoadjuvant Immunotherapy, and Adjuvant Immunotherapy for Cancer

edited by

Rashidul Alam Mahumud

submission deadline 31 Dec 2025 | 1 articles | Viewed by 655 | Submission Open

Keywords: immunotherapy; radioimmunotherapy; neoadjuvant immunothearpy; radiopharmaceuticals

(This special issue belongs to the Section Cancer Therapy)

Pancreatic Cancer: Clinical Standards, Unmet Needs and Future Directions

edited by

Dimitrios H. Roukos

submission deadline 31 Dec 2025 | 1 articles | Viewed by 634 | Submission Open

Keywords: standard clinical management; surgery; neoadjuvant and/or adjuvant treatment; cancer immunotherapy; targeted therapy; detection and elimination of MRD

(This special issue belongs to the Section Clinical Research of Cancer)

Advances in Cancer Data and Statistics: 2nd Edition

edited by

Vesna Zadnik

submission deadline 31 Dec 2025 | 1 articles | Viewed by 571 | Submission Open

Keywords: cancer registries; cancer incidence; cancer survival; population-based studies; cancer risk factors

(This special issue belongs to the Section Cancer Informatics and Big Data)

Latest Advancements in Health-Related Quality of Life Research in Cancer Survivorship (2nd Edition)

edited by

Richard Crevenna

and Thomas Licht

submission deadline 31 Dec 2025 | 1 articles | Viewed by 550 | Submission Open

Keywords: cancer survivors; oncology; psycho-oncology; health-related quality of life; patient-reported outcome measures; self-report

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Lymphoma Biology, Pathology and Stem Cells

edited by

Mingyi Chen

submission deadline 31 Dec 2025 | Viewed by 502 | Submission Open

Keywords: lymphoma biology; pathology; CAR-T; immunotherapy; stem cell transplant

(This special issue belongs to the Section Cancer Pathophysiology)

Technical and Technological Innovations in Head and Neck Cancer Surgery

edited by Marta Filauro

submission deadline 31 Dec 2025 | 1 articles | Viewed by 454 | Submission Open

Keywords: head and neck; squamous cell carcinoma; larynx; oral cavity; free flap; exoscope; TORS

(This special issue belongs to the Section Methods and Technologies Development)

Immunotherapy in Urothelial Carcinoma

edited by Akinori Minato

submission deadline 31 Dec 2025 | 1 articles | Viewed by 425 | Submission Open

Keywords: bladder cancer; upper tract urothelial carcinoma; immune checkpoint inhibitors; tumor microenvironment; biomarkers for immunotherapy; combination therapy; neo-adjuvant/adjuvant immunotherapy; resistance mechanisms; novel immunotherapeutic approaches; personalized medicine

(This special issue belongs to the Section Cancer Immunology and Immunotherapy)

Innovations in Addressing Disparities in Cancer

edited by

Rajesh Singh

and

Shailesh Singh

submission deadline 31 Dec 2025 | Viewed by 388 | Submission Open

Keywords: artificial intelligence on health equity; artificial intelligence and machine learning technologies in cancer care; genomic testing and biomarkers; AI in social determinants of health; health justice; precision medicine and health informatics; innovative cancer care delivery model for overcoming health disparity; equity lens; racial differences in the immunological landscape; racial differences in treatment and disease outcome

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Facial Paralysis in Cancer Patients—from Diagnosis to Treatment and Facial Reanimation

edited by

Barbara Kofler

, Niels van Heerbeek, Giulia Molinari and Benedikt Hofauer

submission deadline 31 Dec 2025 | Viewed by 358 | Submission Open

Keywords: facial nerve; facial nerve reanimation; head and neck cancer; facial reconstructive surgery

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Novel Treatments for Ocular and Periocular Cancers

edited by

Vidhya R. Rao

submission deadline 31 Dec 2025 | Viewed by 337 | Submission Open

Keywords: ocular cancer; intraocular tumor; retinoblastoma; uveal melanoma

(This special issue belongs to the Section Cancer Therapy)

Advances in Cell and Gene Therapy in Tumors: From Bench to Bedside

edited by Shuhang Wang

submission deadline 31 Dec 2025 | Viewed by 320 | Submission Open

Keywords: cell therapy; gene therapy; genetically engineered cells; cancer treatment; clinical trials; pre-clinical study

(This special issue belongs to the Section Cancer Therapy)

Cost-Effectiveness Studies in Cancers

edited by

Ippazio Cosimo Antonazzo

Paolo Cortesi

and

Pietro Ferrara

submission deadline 31 Dec 2025 | Viewed by 320 | Submission Open

Keywords: cancer therapies; cost-effectiveness; cost-utility; cost-consequence; treatment economic impact; health economic; economic sustainability; public health; decision analytical models.

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Innovations in Soft Tissue Sarcoma Diagnosis and Treatment (2nd Edition)

edited by Erlinda M. Gordon,

Sant P. Chawla

and Frederick L. Hall

submission deadline 31 Dec 2025 | Viewed by 280 | Submission Open

Keywords: soft tissue sarcoma; gene therapy; natural killer cell therapy; immune and cell cycle checkpoint inhibitors; targeted therapy

(This special issue belongs to the Section Cancer Causes, Screening and Diagnosis)

Survivorship and Life with Colorectal Cancer

edited by Daniel Steffens, Bora Kim, Rachel Campbell and Kate White

submission deadline 31 Dec 2025 | Viewed by 273 | Submission Open

Keywords: colorectal cancer; survivorship care; implementation; clinical interventions; supportive care

(This special issue belongs to the Section Cancer Survivorship and Quality of Life)

Displaying special issue 751-800 on page 16 of 22.

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