Announcements

25 August 2025
Dr. Anthony S. Zannas Appointed Section Editor-in-Chief of Section “Molecular Biomarkers” in Biomolecules


We are pleased to announce that Dr. Anthony S. Zannas has been appointed Section Editor-in-Chief of the Section “Molecular Biomarkers” in Biomolecules (ISSN: 2218-273X).

The Section “Molecular Biomarkers”, part of MDPI’s open access journal Biomolecules publishes papers in all areas related to molecular biomarker research. This includes the identification, validation, and application of biomarkers in innovative diagnostic procedures, drug discovery/development, and disease pathogenesis.

We seek review and original research articles that address, but are not limited to, the following topics:

  • Predictive biomarkers;
  • Diagnostic biomarkers;
  • Prognostic biomarkers;
  • Pharmacokinetic and pharmacodynamic biomarkers;
  • Optimum biomarker selection and validation;
  • Biomarker development in omics;
  • Biomarker development in molecular medicine.

Dr. Anthony S. Zannas is an Associate Professor and Co-Director of the Carolina Stress Initiative at the Departments of Psychiatry and Genetics, the University of North Carolina. His research interests pertain to epigenetic and other molecular mechanisms linking environmental stress with accelerated aging and disease risk.

The following is a short Q&A with Dr. Anthony S. Zannas, who has shared his vision for the journal with us, as well as his views on the research area and open access publishing:

1. What appealed to you about the journal that made you want to become its Section Editor-in-Chief?

Biomolecules, and MDPI journals more generally, provide an accessible and efficient way of disseminating quality research.

2. What is your vision for this Section?

It covers a critical and timely area of research. Molecular biomarkers are a key tool for the future of biomedical science.

3. What does the future of this field of research look like?

Many of us envision a day when we will have highly reliable biomarkers to apply precision medicine, such as predicting individuals who will develop distinct disease outcomes or those who will respond to specific treatments. Despite many technological advancements, however, there is still a lot of work that needs to be done to materialize this vision.

4. Do you have any suggestions for young researchers in this field?

I always encourage young investigators to persevere and pursue their dreams. Good research takes time, and I believe that perseverance through failures and frustrations is the most important quality of a successful researcher.

5. What do you think of the development of open access in the publishing field?

While there are pros and cons, open access is currently a widespread trend in the field of publication. We can continue working together to support peer-reviewed research that serves the scientific community.

We welcome Dr. Anthony S. Zannas as the Section Editor-in-Chief for “Molecular Biomarkers”, and we look forward to achieving many more milestones under his guidance.

18 August 2025
Biomolecules | Highly Cited Papers Published in 2024–2025 in the “Cellular Biochemistry” Section


As all of the articles published in our journal are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2024 and 2025, which are listed below:

1. “Extracellular Matrix Components and Mechanosensing Pathways in Health and Disease”
by Aikaterini Berdiaki, Monica Neagu, Petros Tzanakakis, Ioanna Spyridaki, Serge Pérez and Dragana Nikitovic
Biomolecules 2024, 14(9), 1186; https://doi.org/10.3390/biom14091186
Full text available online: https://www.mdpi.com/2218-273X/14/9/1186

2. “How Do ROS Induce NETosis? Oxidative DNA Damage, DNA Repair, and Chromatin Decondensation”
by Dhia Azzouz and Nades Palaniyar
Biomolecules 2024, 14(10), 1307; https://doi.org/10.3390/biom14101307
Full text available online: https://www.mdpi.com/2218-273X/14/10/1307

3. “Astrocytes: The Stars in Neurodegeneration?”
by Katarina Stoklund Dittlau and Kristine Freude
Biomolecules 2024, 14(3), 289; https://doi.org/10.3390/biom14030289  
Full text available online: https://www.mdpi.com/2218-273X/14/3/289

4. “Factors and Mechanisms of Thyroid Hormone Activity in the Brain: Possible Role in Recovery and Protection”
by Laura Sabatino, Dominga Lapi and Cristina Del Seppia
Biomolecules 2024, 14(2), 198; https://doi.org/10.3390/biom14020198  
Full text available online: https://www.mdpi.com/2218-273X/14/2/198

5. “Mitochondrial Dysfunction as the Major Basis of Brain Aging”
by Stephen C. Bondy
Biomolecules 2024, 14(4), 402; https://doi.org/10.3390/biom14040402  
Full text available online: https://www.mdpi.com/2218-273X/14/4/402

6. “Space Flight Enhances Stress Pathways in Human Neural Stem Cells”
by Nicholas Carpo, Victoria Tran, Juan Carlos Biancotti, Carlos Cepeda and Araceli Espinosa-Jeffrey
Biomolecules 2024, 14(1), 65; https://doi.org/10.3390/biom14010065  
Full text available online: https://www.mdpi.com/2218-273X/14/1/65

7. “Comparison between the Regenerative and Therapeutic Impacts of Bone Marrow Mesenchymal Stem Cells and Adipose Mesenchymal Stem Cells Pre-Treated with Melatonin on Liver Fibrosis”
by Ahmed Elzainy, Abir El Sadik and Waleed Mohammad Altowayan
Biomolecules 2024, 14(3), 297; https://doi.org/10.3390/biom14030297  
Full text available online: https://www.mdpi.com/2218-273X/14/3/297

8. “Monogenic Disorders of ROS Production and the Primary Anti-Oxidative Defense”
by Nana-Maria Grüning and Markus Ralser
Biomolecules 2024, 14(2), 206; https://doi.org/10.3390/biom14020206  
Full text available online: https://www.mdpi.com/2218-273X/14/2/206

9. “Quercetin: Molecular Insights into Its Biological Roles”
by Hye Joon Boo, Danbi Yoon, Yujeong Choi, Younghyun Kim, Jeong Seok Cha and Jiho Yoo
Biomolecules 2025, 15(3), 313; https://doi.org/10.3390/biom15030313  
Full text available online: https://www.mdpi.com/2218-273X/15/3/313

10. “Autophagy and Cancer: Insights into Molecular Mechanisms and Therapeutic Approaches for Chronic Myeloid Leukemia”
by Mohd Adnan Kausar, Sadaf Anwar, Yusuf Saleem Khan, Ayman A. Saleh, Mai Ali Abdelfattah Ahmed, Simran Kaur, Naveed Iqbal, Waseem Ahmad Siddiqui and Mohammad Zeeshan Najm
Biomolecules 2025, 15(2), 215; https://doi.org/10.3390/biom15020215  
Full text available online: https://www.mdpi.com/2218-273X/15/2/215

18 August 2025
Biomolecules | Highly Cited Papers Published in 2024–2025 in the “Biological Factors” Section


As all of the articles published in our journal are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2024 and 2025, which are listed below:

1. “The Ethylene Biosynthetic Enzymes, 1-Aminocyclopropane-1-Carboxylate (ACC) Synthase (ACS) and ACC Oxidase (ACO): The Less Explored Players in Abiotic Stress Tolerance”
by Sheen Khan, Ameena Fatima Alvi, Sadaf Saify, Noushina Iqbal and Nafees A. Khan
Biomolecules 2024, 14(1), 90; https://doi.org/10.3390/biom14010090  
Full text available online: https://www.mdpi.com/2218-273X/14/1/90

2. “Placenta Extracellular Vesicles: Messengers Connecting Maternal and Fetal Systems”
by Cheryl S. Rosenfeld
Biomolecules 2024, 14(8), 995; https://doi.org/10.3390/biom14080995  
Full text available online: https://www.mdpi.com/2218-273X/14/8/995

3. “From Cure to Crisis: Understanding the Evolution of Antibiotic-Resistant Bacteria in Human Microbiota”
by Hamed Tahmasebi, Neda Arjmand, Marzieh Monemi, Ali Babaeizad, Farnaz Alibabaei, Negar Alibabaei, Aisa Bahar, Valentyn Oksenych and Majid Eslami
Biomolecules 2025, 15(1), 93; https://doi.org/10.3390/biom15010093  
Full text available online: https://www.mdpi.com/2218-273X/15/1/93

4. “Activation of Cannabinoid Type 2 Receptor in Microglia Reduces Neuroinflammation through Inhibiting Aerobic Glycolysis to Relieve Hypertension”
by Ruohan Shan, Yuxiang Zhang, Yiping Shi, Xiaowen Wang, Xueke Wang, Guanying Ma and Qian Li
Biomolecules 2024, 14(3), 333; https://doi.org/10.3390/biom14030333  
Full text available online: https://www.mdpi.com/2218-273X/14/3/333

5. “Mesenchymal Stem Cell-Derived Exosomes: Emerging as a Promising Cell-Free Therapeutic Strategy for Autoimmune Hepatitis”
by Liwen Wu, Longze Zhang, Minglei Huang, Yan Wu, Sikan Jin, Yaqi Zhang, Xinyun Gan, Ting Yu, Guang Yu, Jidong Zhang and Xianyao Wang
Biomolecules 2024, 14(11), 1353; https://doi.org/10.3390/biom14111353  
Full text available online: https://www.mdpi.com/2218-273X/14/11/1353

6. “From Polydeoxyribonucleotides (PDRNs) to Polynucleotides (PNs): Bridging the Gap Between Scientific Definitions, Molecular Insights, and Clinical Applications of Multifunctional Biomolecules”
by Cíntia Marques, Alexandre Porcello, Marco Cerrano, Farid Hadjab, Michèle Chemali, Kelly Lourenço, Basste Hadjab, Wassim Raffoul, Lee Ann Applegate and Alexis E. Laurent
Biomolecules 2025, 15(1), 148; https://doi.org/10.3390/biom15010148  
Full text available online: https://www.mdpi.com/2218-273X/15/1/148

7. “Integrins in Cardiovascular Health and Disease: Molecular Mechanisms and Therapeutic Opportunities”
by Karolina Ławkowska, Klaudia Bonowicz, Dominika Jerka, Yidong Bai and Maciej Gagat
Biomolecules 2025, 15(2), 233; https://doi.org/10.3390/biom15020233  
Full text available online: https://www.mdpi.com/2218-273X/15/2/233

8. “Aromatic Characterisation of Moscato Giallo by GC-MS/MS and Validation of Stable Isotopic Ratio Analysis of the Major Volatile Compounds”
by Mauro Paolini, Alberto Roncone, Lorenzo Cucinotta, Danilo Sciarrone, Luigi Mondello, Federica Camin, Sergio Moser, Roberto Larcher and Luana Bontempo
Biomolecules 2024, 14(6), 710; https://doi.org/10.3390/biom14060710  
Full text available online: https://www.mdpi.com/2218-273X/14/6/710

9. “Investigating the Suitability of Mare’s Milk-Derived Exosomes as Potential Drug Carriers”
by Shynggys Sergazy, Sanzhar Zhetkenev, Zarina Shulgau, Laura Chulenbayeva, Yevgeniy Kamyshanskiy, Madiyar Nurgaziyev, Ayaulym Nurgozhina, Zhanel Mukhanbetzhanova, Kulzhan Berikkhanova, Alexander Gulyayev et al.
Biomolecules 2024, 14(10), 1247; https://doi.org/10.3390/biom14101247  
Full text available online: https://www.mdpi.com/2218-273X/14/10/1247

10. “Mitochondrial Dysfunction in Glycogen Storage Disorders (GSDs)”
by Kumudesh Mishra and Or Kakhlon
Biomolecules 2024, 14(9), 1096; https://doi.org/10.3390/biom14091096  
Full text available online: https://www.mdpi.com/2218-273X/14/9/1096

13 August 2025
Meet Us at the 34th Annual Conference of the European Society for Biomaterials, 7–11 September 2025, Turin, Italy


MDPI is excited to announce its participation as an exhibitor at the 34th Annual Conference of the European Society for Biomaterials, taking place in Turin, Italy, from 7 to 11 September 2025.

The motto of the ESB 2025 conference is “Biomaterials on the horizon”. The horizon opens our mind to new and at times unexpected discoveries and reminds us of the charming challenges of our research. The motto is inspired by the fast development of new sources for multifunctional materials, and groundbreaking technologies that enable new structures and devices that improve healthcare, prevent pathologies, and allow patient-oriented therapies.

With all this in mind, in an exciting and dynamic environment, participants to ESB 2025 will share and discuss traditional areas of research, such as clinical translation, regenerative medicine, in vitro models, drug delivery, and antibacterial treatments, but also emerging themes, such as biomaterial-assisted gene and cell therapy, investigations at the (bio)molecular and cell scale, as well as crosscutting topics, such as artificial intelligence in biomaterial research, ethics, the 3Rs principle, and regulatory frameworks. Particular attention will be given to the Sustainable Development Goals, in which the role of the biomaterials is increasingly relevant.

The following MDPI journals will be presented at the conference:

If you are attending this conference, please feel free to get in contact with us. Our delegates look forward to meeting you in person at booth #21 and answering any questions that you may have. For more information about the conference, please visit the following link: https://esb2025.org/.

31 July 2025
MDPI INSIGHTS: The CEO's Letter #25 - 8,000 Staff Worldwide, Korea Visit, 100,000 Preprints, Malaysia Roundtable, Canada Consortium Deal

Welcome to the MDPI Insights: The CEO's Letter.

In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.


Opening Thoughts

Talent Drives Our Progress

For the first time in MDPI’s history, we now have over 8,000 colleagues across the company. I would like to take a moment to celebrate this milestone and acknowledge the driving force behind our growth and success: our people.

As the world’s leading fully open access publisher, MDPI has grown thanks to the dedication, talent, and teamwork of colleagues across the company. Already halfway through 2025, we’ve welcomed nearly 2,000 new colleagues. 

“Our achievements are also about the people behind them”

We now manage over 475 journals, with 298 receiving an Impact Factor, and hundreds more indexed in major databases, including 343 in Scopus, and 92 by PubMed. As the reach and impact of our journals continues to grow, so does the need for dedicated and qualified teams to support that growth. Thus, attracting and retaining exceptional talent remains a cornerstone of our success.

Our achievements are not just about the results of journal expansion, however: they’re about the people behind them. From our hardworking editors to our meticulous English editing and production teams – from our journal relationship specialists, public relations, marketing and communications professionals to our conference teams and the project teams behind Preprints, Scilit, SciProfiles, JAMS and more. Our success reflects the work of thousands of people showing up each day, taking pride in their work, and committed to excellence and service.

What we’re doing to support talent:

  • Investing in onboarding and training to help new colleagues feel welcomed and empowered to thrive.
  • Creating clearer career paths across all functions, from editorial to communications and beyond.
  • Launching mentorship programs and internal knowledge-sharing sessions to promote growth and collaboration.
  • Evolving our recognition and rewards programs to better celebrate your contributions.
  • Expanding our training systems and platforms.

MDPI’s in-house training department offers over 215 training courses, covering topics from editorial development to cross-cultural collaboration. In 2024 alone, we had 44 full-time trainers and 196 part-time training assistants supporting the learning and development needs of colleagues worldwide. These efforts ensure our teams are equipped with the skills and confidence to grow professionally and contribute meaningfully.

Over two-thirds of our workforce is editorial, and of our more than 5,400 editors, 87% hold a Master’s degree and 6% a PhD. Their collective contributions are central to delivering a high-quality publishing experience and supporting global academic communication.

As we celebrate this milestone, we also aim to continue on a path of steady and sustainable growth, one that balances journal expansion with investment in people, outreach, processes, and innovation. Together, we are shaping the future of open access and academic publishing. Thank you for your hard work, your ideas, and your commitment to serving the global research community.

Let’s continue working together to create a culture where great talent grows and every colleague feels valued.

Impactful Research

Visiting South Korea: Building Connections and Supporting the MDPI Seoul Office

In July, I had the opportunity to visit our team in Seoul and engage directly with academic communities in South Korea. The visit focused on deepening MDPI’s relationships with local universities, institutions, and partners, and supporting the great work of our colleagues at the MDPI Seoul office.

Korea Association of Private University Libraries (KAPUL) Conference

A highlight of the visit was our participation in the Korea Association of Private University Libraries (KAPUL) Conference, where we presented to over 100 academic librarians. I delivered a keynote speech titled “The Evolving Publishing Landscape: Open Access and Beyond,” while my colleague Dr. Jisuk Kang (Public Affairs Specialist) shared insights in her presentation, “Inside MDPI: Editorial Practices & Research Integrity.”

Facts & Figures: South Korea

  • South Korea is MDPI’s sixth-largest publishing country by article volume (over 90,000 MDPI papers published to date).
  • In 2024, Korea ranked 16th globally by total publications, and 6th (among these top 20 countries) by citation impact.
  • 52% of Korean publications in 2024 were OA – and 73% of those were Gold OA.
  • MDPI published about 20% of all OA papers from Korea in 2024.
  • Over 2,000 active Editorial Board Members from South Korea contribute to MDPI journals, with 11 Section Editors-in-Chief.
  • We currently have 11 Institutional Open Access Program agreements and two society partnerships in Korea:
    • Korean Society of Pharmaceutical Sciences and Technology (with MDPI journal Pharmaceutics)
    • Korean Tribology Society (with MDPI journal Coatings)

MDPI Seoul Office and the First Korea Salon

Our Seoul office serves as a regional hub for marketing, communications, and community engagement. It continues to grow in size and influence, prioritizing supporting scholar visits, conference sponsorships, and outreach events such as the recent MDPI Korea Salon.

The inaugural Salon, themed “Exploring Research Trends in Medical Publishing, Ethics, and AI,” brought together over 20 scholars and Editorial Board members serving MDPI journals.

Thank you to our guest speakers including Professors Young-Joon Surh of Seoul National University, Kwang-Sig Lee of Korea University, and Jin-Won Noh of Yonsei University who presented on the landscape of medicine in South Korea and across the globe. The Salon also included presentations from MDPI colleagues on Open Access, ethics, and how the IOAP can support researchers in this field.

“Our Seoul office continues to grow in size and influence”

Looking Ahead

MDPI is already the leading OA publisher in South Korea, yet challenges and misconceptions around OA and APCs remain. Visits like this one, along with the ongoing efforts of our Seoul office, are important to building understanding, trust, and long-term relationships with the local academic community.

A big thank-you to our colleagues in Seoul for their warm hospitality, professionalism, and energy! Our new office is well situated, staffed, and ready to grow. This visit marked an important step forward in our continued mission to support global research communities and advance Open Science.

Inside MDPI

Preprints.org Reaches 100,000 Preprints: A Major Milestone for MDPI and Open Science

In case you missed it, Preprints.org recently surpassed 100,000 preprints posted. This is a major milestone for our platform and one worth celebrating.

Preprints are a key pillar of the Open Science movement, which promotes transparency, equity, and faster knowledge-sharing through initiatives such as Open Access, Open Data, Open Source, and Open Peer Review. The benefits of Open Science extend beyond researchers, as they support funders, educators, policymakers, and the public in advancing discovery and innovation.

What is behind the 100,000 preprints milestone?

Since its launch in 2016, Preprints.org has grown into one of the world’s leading preprint platforms, now ranked fifth globally by publication volume.

More than 350,000 researchers have contributed, helping shape this dynamic and collaborative space for sharing early-stage research across all disciplines.

Read the full announcement here:
https://www.mdpi.com/about/announcements/12202

“Preprints.org has grown into one of the world’s leading preprint platforms”

Some quick facts worth noting:

  • About 56% of the preprints on Preprints.org are later published in peer-reviewed journals.
  • The platform is now indexed in Web of Science (Preprint Citation Index), Europe PMC, and Crossref, helping improve visibility and trust in the preprints shared.
  • Recent upgrades – including a revamped website, new features such as search subscriptions, curated reading lists, and community feedback tools (PREreview) – show our commitment to developing Preprints.org in line with researchers’ needs.

This growth and progress would not be possible without the dedication of the Preprints.org team, our Advisory Board members, screeners, and colleagues across MDPI who support the platform’s development. This milestone is a reminder of our shared mission: to accelerate scientific communication and build a more open, transparent, and inclusive research ecosystem.

I’m excited to see what’s ahead as we approach Preprints.org’s 10-year anniversary in 2026!

Coming Together for Science

Malaysia Media Roundtable: Educating on Open Access and MDPI’s Presence in Southeast Asia

At the end of June, I had the opportunity to participate in a strategic media roundtable in Kuala Lumpur, focused on raising awareness about the importance of Open Access (OA) and on MDPI’s growing presence in Southeast Asia.

We welcomed five Malaysian media outlets for an engaging private session that included presentations and open discussion.

I gave an overview of the benefits of Open Access, MDPI’s global developments, and our collaborations in Malaysia.

My colleague Yu Nwe Soe (Public Relations Specialist), presented on our editorial process, helping to clarify how MDPI supports authors and maintains research quality.

We were also joined by two local Editorial Board Members (EBMs) who offered first-hand insights into their experiences working with MDPI and how OA has shaped their publishing choices.

The discussion covered a range of questions from the press, from OA publishing models to editorial standards, and highlighted MDPI’s unique contribution to accelerating scientific communication in the region.

As the leading fully OA publisher, we see it as our responsibility to continue educating research communities and the broader public on the impact of OA, especially in emerging and high-growth academic markets.

Spotlight on Malaysia

Malaysia continues to rise as a regional research hub, with five universities ranked in the global top 200 and 11 subjects in the global top 50. In 2024, Malaysia ranked 2nd in Southeast Asia in total publication output, 10th in Asia, and 25th globally.

MDPI’s presence in Malaysia:

  • Over 21,000 research articles published to date from Malaysian institutions
  • More than 1,100 articles published in 2024 alone
  • In the period 2020–2024, 54% of Malaysia’s total publications were OA
  • 36 EBMs from Malaysia, across 27 MDPI journals
  • Around 100 conferences sponsored in Malaysia in the past five years
  • MDPI is hosting the 2nd International Conference on AI Sensors and Transducers in Kuala Lumpur (29 July- 3 August 2025)

Media Coverage & Editorial Voices

Following the roundtable, we saw positive coverage across several local outlets, with articles highlighting MDPI’s role in empowering Malaysian researchers. Notable pieces included:

Our local EBMs also shared their perspectives:

Prof. Denny Ng Kok Sum (Sunway University, EBM of MDPI journal Processes) and Prof. Lee (EBM of MDPI journal Bacteria) share their experiences with MDPI and the role Open Access plays in their publication decisions.

“We see it as our responsibility to continue educating research communities on the impact of OA”

“I didn’t want my work stuck behind a paywall.”
— Prof. Denny Ng Kok Sum, Sunway University, Processes Editorial Board Member

“Open Access opens doors for collaboration and visibility, especially in fast-developing regions like ours.”
— Prof. Lee, Bacteria Editorial Board Member

This roundtable marked another step in building trust, understanding, and collaboration in Southeast Asia. A big thank-you to the MDPI Malaysia team and all those who contributed to the event’s success.

Closing Thoughts

MDPI Signs First North American Agreement with Canadian Consortium

We are proud to announce a major milestone for MDPI Canada and an important step forward for OA in North America.

In July, our Toronto office finalized MDPI’s first North American consortium agreement with the Federal Science Libraries Network (FSLN). This is a significant achievement that strengthens our expansion in Canada and reinforces our global commitment to supporting Open Science.

This two-year agreement gives Canadian federal agencies access to MDPI’s IOAP, including discounted article processing charges for affiliated researchers across our portfolio of over 475 OA journals. It lowers barriers for Canadian scientists to share their work more openly and reach a global audience.


Ryan Siu, Institutional Partnerships Manager at MDPI.

“The Open Science landscape in Canada is rapidly evolving, with the Tri-Agency Open Access Policy set for renewal by the end of 2025. This reflects ongoing efforts to foster greater scientific transparency and accessibility at a national policy level,” says Ryan Siu, Institutional Partnerships Manager at MDPI.

“Our new agreement with FSLN represents our shared commitment to further these efforts and foster wider readership. By aligning with these initiatives, we make progress towards research that’s both inclusive and impactful, benefiting local and global communities alike.”

Participating FSLN institutions include:

  • Agriculture and Agri-Food Canada
  • Environment and Climate Change Canada
  • Health Canada
  • National Research Council Canada
  • Natural Resources Canada

By partnering with some of Canada’s largest science-based agencies, we reaffirm our goal of advancing OA across continents. We look forward to developing our support for Canadian researchers and continuing to drive progress in Open Science across North America and beyond.

Stefan Tochev
Chief Executive Officer
MDPI AG

29 July 2025
Meet Us at the 61st Annual Meeting European Association for the Study of Diabetes (EASD 2025), 15–19 September 2025, Vienna, Austria


Conference: 61st Annual Meeting European Association for the Study of Diabetes (EASD 2025)
Date: 15–19 September 2025
Location: Vienna, Austria

MDPI will be attending the 61st Annual Meeting European Association for the Study of Diabetes (EASD 2025), which will be held from 15 to 19 September 2025, as an exhibitor. We welcome researchers from diverse backgrounds to attend and share their latest ideas with us.

The EASD Annual Meeting is an excellent opportunity to stay up to date with recent developments in the diabetes field. The programme features groundbreaking basic research, cutting-edge clinical trial results and in-depth expert debates. We are pleased to attend the conference and also meet with colleagues from around the world and be part of the key discussions that will shape the future of diabetes research and care. Your participation will significantly contribute to the medical discourse and enhance the conference’s impact within the diabetes field.

The following open access journals will be represented at the conference:

  • Biomedicines;
  • Diabetology;
  • JCM;
  • Medicina;
  • IJERPH;
  • Obesities;
  • Nutrients;
  • Biomolecules;
  • LabMed;
  • Lipidology;
  • Metabolites;
  • Endocrines.

If you are planning to attend the above conference, please do not hesitate to start an online conversation with us. Our delegates look forward to meeting you in person at the booth and answering any questions that you may have. For more information about the conference, please visit the following website: https://www.easd.org/annual-meeting/easd-2025.html.

29 July 2025
Meet Us at the ASHG 2025 Annual Meeting, 14–18 October 2025, Boston, USA


Conference:
ASHG 2025 Annual Meeting
Organization: American Society of Human Genetics
Date: 14–18 October 2025
Place: Boston, USA

MDPI will attend the ASHG 2025 Annual Meeting, held in Boston, USA, from 14 to 18 October 2025.

The ASHG Annual Meeting is the largest human genetics and genomics meeting and exposition in the world. Held in the fall, it provides a forum for the presentation and discussion of cutting-edge science in all areas of human genetics. Highlights include invited symposia; abstract-driven plenary, platform, and poster sessions; education/trainee workshops; and career opportunities and networking events.

The following MDPI journals will be represented:

  • Genes;
  • Biomedicines;
  • IJMS;
  • Biomolecules;
  • BioMedInformatics;
  • Applied Biosciences;
  • DNA;
  • Cardiogenetics;
  • Vaccines;
  • Epigenomes;
  • Biology;
  • CIMB;
  • Diseases;
  • J;
  • JPM.

If you plan on attending this conference, please stop by our booth #1975 and speak with us. Our delegates look forward to meeting you in person and answering any questions that you may have.

For more information about the conference, please visit the following website: https://www.ashg.org/meetings/2025meeting/.

23 July 2025
Biomolecules | Highly Cited Papers in 2024 in the “Chemical Biology” Section

As all of the articles published in our journal are open access, meaning you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2024, which are listed below.

1. “Mitochondrial Reactive Oxygen Species in Infection and Immunity”
by Arunima Mukherjee, Krishna Kanta Ghosh, Sabyasachi Chakrabortty, Balázs Gulyás, Parasuraman Padmanabhan and Writoban Basu Ball
Biomolecules 2024, 14(6), 670; https://doi.org/10.3390/biom14060670
Full text available online: https://www.mdpi.com/2218-273X/14/6/670

2. “Recent Advances in the Use of Vitamin D Organic Nanocarriers for Drug Delivery”
by Ioanna Aggeletopoulou, Maria Kalafateli, Georgios Geramoutsos and Christos Triantos
Biomolecules 2024, 14(9), 1090; https://doi.org/10.3390/biom14091090
Full text available online: https://www.mdpi.com/2218-273X/14/9/1090

3. “Terpenoid-Mediated Targeting of STAT3 Signaling in Cancer: An Overview of Preclinical Studies”
by Fahad Khan, Pratibha Pandey, Meenakshi Verma and Tarun Kumar Upadhyay
Biomolecules 2024, 14(2), 200; https://doi.org/10.3390/biom14020200
Full text available online: https://www.mdpi.com/2218-273X/14/2/200

4. “A Survey on Computational Methods in Drug Discovery for Neurodegenerative Diseases”
by Caterina Vicidomini, Francesco Fontanella, Tiziana D’Alessandro and Giovanni N. Roviello
Biomolecules 2024, 14(10), 1330; https://doi.org/10.3390/biom14101330
Full text available online: https://www.mdpi.com/2218-273X/14/10/1330

5. “Effect of Essential Oil Components on the Activity of Steroidogenic Cytochrome P450”
by Katyayani Sharma, Angelo Lanzilotto, Jibira Yakubu, Søren Therkelsen, Clarissa Daniela Vöegel, Therina Du Toit, Flemming Steen Jørgensen and Amit V. Pandey
Biomolecules 2024, 14(2), 203; https://doi.org/10.3390/biom14020203
Full text available online: https://www.mdpi.com/2218-273X/14/2/203

6. “Exogenous Iron Induces Mitochondrial Lipid Peroxidation, Lipofuscin Accumulation, and Ferroptosis in H9c2 Cardiomyocytes”
by Konstantin G. Lyamzaev, He Huan, Alisa A. Panteleeva, Ruben A. Simonyan, Armine V. Avetisyan and Boris V. Chernyak
Biomolecules 2024, 14(6), 730; https://doi.org/10.3390/biom14060730
Full text available online: https://www.mdpi.com/2218-273X/14/6/730

7. “Ladostigil Reduces the Adenoside Triphosphate/Lipopolysaccharide-Induced Secretion of Pro-Inflammatory Cytokines from Microglia and Modulate-Immune Regulators, TNFAIP3, and EGR1”
by Fanny Reichert, Keren Zohar, Elyad Lezmi, Tsiona Eliyahu, Shlomo Rotshenker, Michal Linial and Marta Weinstock
Biomolecules 2024, 14(1), 112; https://doi.org/10.3390/biom14010112
Full text available online: https://www.mdpi.com/2218-273X/14/1/112

8. “How the Western Diet Thwarts the Epigenetic Efforts of Gut Microbes in Ulcerative Colitis and Its Association with Colorectal Cancer”
by Avisek Majumder and Shabana Bano
Biomolecules 2024, 14(6), 633; https://doi.org/10.3390/biom14060633
Full text available online: https://www.mdpi.com/2218-273X/14/6/633

9. “Complex Pathophysiology of Acute Kidney Injury (AKI) in Aging: Epigenetic Regulation, Matrix Remodeling, and the Healing Effects of H2S”
by Shreyasi Gupta, Subhadeep Mandal, Kalyan Banerjee, Hebah Almarshood, Sathnur B. Pushpakumar and Utpal Sen
Biomolecules 2024, 14(9), 1165; https://doi.org/10.3390/biom14091165
Full text available online: https://www.mdpi.com/2218-273X/14/9/1165

10. “A High-Throughput Screening of a Natural Products Library for Mitochondria Modulators”
by Emmanuel Makinde, Linlin Ma, George D. Mellick and Yunjiang Feng
Biomolecules 2024, 14(4), 440; https://doi.org/10.3390/biom14040440
Full text available online: https://www.mdpi.com/2218-273X/14/4/440

23 July 2025
Biomolecules | Highly Cited Papers in 2024 in the “Natural and Bio-derived Molecules” Section

As all of the articles published in our journal are open access, meaning you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2024, which are listed below:

1. “Exploring FDA-Approved Frontiers: Insights into Natural and Engineered Peptide Analogues in the GLP-1, GIP, GHRH, CCK, ACTH, and α-MSH Realms”
by Othman Al Musaimi
Biomolecules 2024, 14(3), 264; https://doi.org/10.3390/biom14030264
Full text available online: https://www.mdpi.com/2218-273X/14/3/264

2. “Third-Generation Tetracyclines: Current Knowledge and Therapeutic Potential”
by Dimitris Kounatidis, Maria Dalamaga, Eugenia Grivakou, Irene Karampela, Petros Koufopoulos, Vasileios Dalopoulos, Nikolaos Adamidis, Eleni Mylona, Aikaterini Kaziani and Natalia G. Vallianou
Biomolecules 2024, 14(7), 783; https://doi.org/10.3390/biom14070783
Full text available online: https://www.mdpi.com/2218-273X/14/7/783

3. “Curcumin and Resveratrol: Nutraceuticals with so Much Potential for Pseudoachondroplasia and Other ER-Stress Conditions”
by Karen L. Posey
Biomolecules 2024, 14(2), 154; https://doi.org/10.3390/biom14020154
Full text available online: https://www.mdpi.com/2218-273X/14/2/154

4. “Comprehensive Review of Olea europaea: A Holistic Exploration into Its Botanical Marvels, Phytochemical Riches, Therapeutic Potentials, and Safety Profile”
by Hamza Elhrech, Oumayma Aguerd, Chaimae El Kourchi, Monica Gallo, Daniele Naviglio, Imane Chamkhi and Abdelhakim Bouyahya
Biomolecules 2024, 14(6), 722; https://doi.org/10.3390/biom14060722
Full text available online: https://www.mdpi.com/2218-273X/14/6/722

5. “Research Progress on Sesquiterpenoids of Curcumae Rhizoma and Their Pharmacological Effects”
by Ting Cui, Bo-Yu Li, Fei Liu and Liang Xiong
Biomolecules 2024, 14(4), 387; https://doi.org/10.3390/biom14040387
Full text available online: https://www.mdpi.com/2218-273X/14/4/387

6. “Bacteriocins in Cancer Treatment: Mechanisms and Clinical Potentials”
by Yiwen Wang, Yue Wang, Tao Sun and Junnan Xu
Biomolecules 2024, 14(7), 831; https://doi.org/10.3390/biom14070831
Full text available online: https://www.mdpi.com/2218-273X/14/7/831

7. “Assessment of Antimicrobial and Cytotoxic Activities of Liposomes Loaded with Curcumin and Lippia origanoides Essential Oil”
by Juan Pablo Bedoya-Agudelo, Jhon Esteban López-Carvajal, Edwin Stiven Quiguanás-Guarín, Nestor Cardona, Leonardo Padilla-Sanabria and Jhon Carlos Castaño-Osorio
Biomolecules 2024, 14(7), 851; https://doi.org/10.3390/biom14070851
Full text available online: https://www.mdpi.com/2218-273X/14/7/851

8. “Gypenoside XVII Reduces Synaptic Glutamate Release and Protects against Excitotoxic Injury in Rats”
by Cheng-Wei Lu, Tzu-Yu Lin, Kuan-Ming Chiu, Ming-Yi Lee and Su-Jane Wang
Biomolecules 2024, 14(5), 589; https://doi.org/10.3390/biom14050589
Full text available online: https://www.mdpi.com/2218-273X/14/5/589

9. “Effects of Ginger (Zingiber officinale) on the Hallmarks of Aging”
by Maima Matin, Tanuj Joshi, Dongdong Wang, Nikolay T. Tzvetkov, Farhan Bin Matin, Agnieszka Wierzbicka, Artur Jóźwik, Jarosław Olav Horbańczuk and Atanas G. Atanasov
Biomolecules 2024, 14(8), 940; https://doi.org/10.3390/biom14080940
Full text available online: https://www.mdpi.com/2218-273X/14/8/940

10. “Postbiotics of Naturally Fermented Synbiotic Mixture of Rice Water Aids in Promoting Colonocyte Health”
by Charumathi Anbalagan, Sangeetha Kadapakkam Nandabalan, Pavithra Sankar, Prasanna Srinivasan Rajaram, Karthick Govindaraj, Secunda Rupert and Jeswanth Sathyanesan
Biomolecules 2024, 14(3), 344; https://doi.org/10.3390/biom14030344
Full text available online: https://www.mdpi.com/2218-273X/14/3/344

23 July 2025
Biomolecules | Highly Cited Papers in 2024 in the “Molecular Medicine” Section

As all of the articles published in our journal are open access, meaning you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2024, which are listed below:

1. “The Role of MUC1 in Renal Cell Carcinoma”
by Martina Milella, Monica Rutigliano, Francesco Lasorsa, Matteo Ferro, Roberto Bianchi, Giuseppe Fallara, Felice Crocetto, Savio Domenico Pandolfo, Biagio Barone, Antonio d’Amati et al.
Biomolecules 2024, 14(3), 315; https://doi.org/10.3390/biom14030315
Full text available online: https://www.mdpi.com/2218-273X/14/3/315

2. “The Role of the Brain-Derived Neurotrophic Factor in Chronic Pain: Links to Central Sensitization and Neuroinflammation”
by Huan-Yu Xiong, Jolien Hendrix, Siobhan Schabrun, Arne Wyns, Jente Van Campenhout, Jo Nijs and Andrea Polli
Biomolecules 2024, 14(1), 71; https://doi.org/10.3390/biom14010071
Full text available online: https://www.mdpi.com/2218-273X/14/1/71

3. “Polyphenols: Role in Modulating Immune Function and Obesity”
by Md Abdullah Al Mamun, Ahmed Rakib, Mousumi Mandal, Santosh Kumar, Bhupesh Singla and Udai P. Singh
Biomolecules 2024, 14(2), 221; https://doi.org/10.3390/biom14020221
Full text available online: https://www.mdpi.com/2218-273X/14/2/221

4. “Blood Biomarkers of Alzheimer’s Disease and Cognition: A Literature Review”
by Greta Garcia-Escobar, Rosa Maria Manero, Aida Fernández-Lebrero, Angel Ois, Irene Navalpotro-Gómez, Victor Puente-Periz, José Contador-Muñana, Isabel Estragués-Gazquez, Albert Puig-Pijoan and Joan Jiménez-Balado
Biomolecules 2024, 14(1), 93; https://doi.org/10.3390/biom14010093
Full text available online: https://www.mdpi.com/2218-273X/14/1/93

5. “The Possible Roles of IL-4/IL-13 in the Development of Eosinophil-Predominant Severe Asthma”
by Kazuyuki Nakagome and Makoto Nagata
Biomolecules 2024, 14(5), 546; https://doi.org/10.3390/biom14050546
Full text available online: https://www.mdpi.com/2218-273X/14/5/546

6. “Real-World Safety and Effectiveness of Voretigene Neparvovec: Results up to 2 Years from the Prospective, Registry-Based PERCEIVE Study”
by M. Dominik Fischer, Francesca Simonelli, Jayashree Sahni, Frank G. Holz, Rainer Maier, Christina Fasser, Andrea Suhner, Daniel P. Stiehl, Bee Chen, Isabelle Audo et al.
Biomolecules 2024, 14(1), 122; https://doi.org/10.3390/biom14010122
Full text available online: https://www.mdpi.com/2218-273X/14/1/122

7. “Kidney Fibrosis and Oxidative Stress: From Molecular Pathways to New Pharmacological Opportunities”
by Francesco Patera, Leonardo Gatticchi, Barbara Cellini, Davide Chiasserini and Gianpaolo Reboldi
Biomolecules 2024, 14(1), 137; https://doi.org/10.3390/biom14010137
Full text available online: https://www.mdpi.com/2218-273X/14/1/137

8. “Hydrogen Sulfide (H2S)/Polysulfides (H2Sn) Signalling and TRPA1 Channels Modification on Sulfur Metabolism”
by Hideo Kimura
Biomolecules 2024, 14(1), 129; https://doi.org/10.3390/biom14010129
Full text available online: https://www.mdpi.com/2218-273X/14/1/129

9. “Reproductive and Oncologic Outcomes in Young Women with Stage IA and Grade 2 Endometrial Carcinoma Undergoing Fertility-Sparing Treatment: A Systematic Review”
by Andrea Etrusco, Antonio Simone Laganà, Vito Chiantera, Mislav Mikuš, Hafiz Muhammad Arsalan, Antonio d’Amati, Amerigo Vitagliano, Ettore Cicinelli, Alessandro Favilli and Antonio D’Amato
Biomolecules 2024, 14(3), 306; https://doi.org/10.3390/biom14030306
Full text available online: https://www.mdpi.com/2218-273X/14/3/306

10. “Brain-Derived Neurotrophic Factor, Nociception, and Pain”
by Adalberto Merighi
Biomolecules 2024, 14(5), 539; https://doi.org/10.3390/biom14050539
Full text available online: https://www.mdpi.com/2218-273X/14/5/539

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