Announcements

10 September 2024
Biomolecules | Highly Cited Papers in 2022–2023 in the Section “Molecular Biology”


As all of the articles published in our journal are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below.

1. “Molecular Biomarkers in Cancer”
by Virinder Kaur Sarhadi and Gemma Armengol
Biomolecules 2022, 12(8), 1021; https://doi.org/10.3390/biom12081021
Full text available online: https://www.mdpi.com/2218-273X/12/8/1021

2. “Recent Advances in Poly(α-L-glutamic acid)-Based Nanomaterials for Drug Delivery”
by Yu Zhang, Wenliang Song, Yiming Lu, Yixin Xu, Changping Wang, Deng-Guang Yu and Il Kim
Biomolecules 2022, 12(5), 636; https://doi.org/10.3390/biom12050636
Full text available online: https://www.mdpi.com/2218-273X/12/5/636

3. “Melittin-Based Nano-Delivery Systems for Cancer Therapy”
by Anqi Wang, Yuan Zheng, Wanxin Zhu, Liuxin Yang, Yang Yang and Jinliang Peng
Biomolecules 2022, 12(1), 118; https://doi.org/10.3390/biom12010118
Full text available online: https://www.mdpi.com/2218-273X/12/1/118

4. “Recent Advances in Strategies for Addressing Hypoxia in Tumor Photodynamic Therapy”
by Liang Hong, Jiangmin Li, Yali Luo, Tao Guo, Chenshuang Zhang, Sha Ou, Yaohang Long and Zuquan Hu
Biomolecules 2022, 12(1), 81; https://doi.org/10.3390/biom12010081
Full text available online: https://www.mdpi.com/2218-273X/12/1/81

5. “Targeting Oxidative Stress Involved in Endometriosis and Its Pain”
by Lauren Clower, Taylor Fleshman, Werner J. Geldenhuys and Nalini Santanam
Biomolecules 2022, 12(8), 1055; https://doi.org/10.3390/biom12081055
Full text available online: https://www.mdpi.com/2218-273X/12/8/1055

6. “Role of Fibroblasts and Myofibroblasts on the Pathogenesis and Treatment of Pelvic Organ Prolapse”
by Zeliha Guler and Jan Paul Roovers
Biomolecules 2022, 12(1), 94; https://doi.org/10.3390/biom12010094
Full text available online: https://www.mdpi.com/2218-273X/12/1/94

7. “Methacrylated Cartilage ECM-Based Hydrogels as Injectables and Bioinks for Cartilage Tissue Engineering”
by Kevin Behan, Alexandre Dufour, Orquidea Garcia and Daniel Kelly
Biomolecules 2022, 12(2), 216; https://doi.org/10.3390/biom12020216
Full text available online: https://www.mdpi.com/2218-273X/12/2/216

8. “Cellulose Nanofiber-Based Aerogels from Wheat Straw: Influence of Surface Load and Lignin Content on Their Properties and Dye Removal Capacity”
by Ramón Morcillo-Martín, Eduardo Espinosa, Laura Rabasco-Vílchez, Laura M. Sanchez,Jorge de Haro and Alejandro Rodríguez
Biomolecules 2022, 12(2), 232; https://doi.org/10.3390/biom12020232
Full text available online: https://www.mdpi.com/2218-273X/12/2/232

9. “Wood Waste from Fruit Trees: Biomolecules and Their Applications in Agri-Food Industry”
by Maria Jose Aliaño-González, Julien Gabaston, Victor Ortiz-Somovilla and Emma Cantos-Villar
Biomolecules 2022, 12(2), 238; https://doi.org/10.3390/biom12020238
Full text available online: https://www.mdpi.com/2218-273X/12/2/238

10. “Effects of Glucose Metabolism, Lipid Metabolism, and Glutamine Metabolism on Tumor Microenvironment and Clinical Implications”
by Longfei Zhu, Xuanyu Zhu and Yan Wu
Biomolecules 2022, 12(4), 580; https://doi.org/10.3390/biom12040580
Full text available online: https://www.mdpi.com/2218-273X/12/4/580

10 September 2024
Biomolecules | Highly Cited Papers in 2022–2023 in the Section “Molecular Genetics”


As all of the articles published in our journal are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below.

1. “Folic Acid, Folinic Acid, 5 Methyl TetraHydroFolate Supplementation for Mutations That Affect Epigenesis through the Folate and One-Carbon Cycles”
by Yves Menezo, Kay Elder, Arthur Clement and Patrice Clement
Biomolecules 2022, 12(2), 197; https://doi.org/10.3390/biom12020197
Full text available online: https://www.mdpi.com/2218-273X/12/2/197

2. “Acetylation, Phosphorylation, Ubiquitination (Oh My!): Following Post-Translational Modifications on the Ubiquitin Road”
by Rachel E. Lacoursiere, Dania Hadi and Gary S. Shaw
Biomolecules 202212(3), 467; https://doi.org/10.3390/biom12030467
Full text available online: https://www.mdpi.com/2218-273X/12/3/467

3. “Plasma Exosome-Derived microRNAs as Potential Diagnostic and Prognostic Biomarkers in Brazilian Pancreatic Cancer Patients”
by Anelis Maria Marin, Sibelle Botogosque Mattar, Rafaela Ferreira Amatuzzi, Roger Chammas, Miyuki Uno, Dalila Luciola Zanette and Mateus Nóbrega Aoki
Biomolecules 202212(6), 769; https://doi.org/10.3390/biom12060769
Full text available online: https://www.mdpi.com/2218-273X/12/6/769

4. “Glycemic Control and the Heart: The Tale of Diabetic Cardiomyopathy Continues”
by Miriam Longo, Lorenzo Scappaticcio, Paolo Cirillo, Antonietta Maio, Raffaela Carotenuto, Maria Ida Maiorino, Giuseppe Bellastella and Katherine Esposito
Biomolecules 202212(2), 272; https://doi.org/10.3390/biom12020272
Full text available online: https://www.mdpi.com/2218-273X/12/2/272

5. “Next-Generation Sequencing Gene Panels in Inheritable Cardiomyopathies and Channelopathies: Prevalence of Pathogenic Variants and Variants of Unknown Significance in Uncommon Genes”
by Cristina Mazzaccara, Raffaella Lombardi, Bruno Mirra, Ferdinando Barretta, Maria Valeria Esposito, Fabiana Uomo, Martina Caiazza, Emanuele Monda, Maria Angela Losi, Giuseppe Limongelli et al.
Biomolecules 202212(10), 1417; https://doi.org/10.3390/biom12101417
Full text available online: https://www.mdpi.com/2218-273X/12/10/1417

6. “Optimized AAV Vectors for TMC1 Gene Therapy in a Humanized Mouse Model of DFNB7/11”
by Irina Marcovich, Nicholas K. Baer, Olga Shubina-Oleinik, Rachel Eclov, Clayton W. Beard and Jeffrey R. Holt
Biomolecules 202212(7), 914; https://doi.org/10.3390/biom12070914
Full text available online: https://www.mdpi.com/2218-273X/12/7/914

7. “Myocardial Inflammation as a Manifestation of Genetic Cardiomyopathies: From Bedside to the Bench”
by Giovanni Peretto, Elena Sommariva, Chiara Di Resta, Martina Rabino, Andrea Villatore, Davide Lazzeroni, Simone Sala, Giulio Pompilio and Leslie T. Cooper
Biomolecules 202313(4), 646; https://doi.org/10.3390/biom13040646
Full text available online: https://www.mdpi.com/2218-273X/13/4/646

8. “Advances and Challenges in Spatial Transcriptomics for Developmental Biology”
by Kyongho Choe, Unil Pak, Yu Pang, Wanjun Hao and Xiuqin Yang
Biomolecules 202313(1), 156; https://doi.org/10.3390/biom13010156
Full text available online: https://www.mdpi.com/2218-273X/13/1/156

9. “Epigenetic Reprogramming of the Inflammatory Response in Obesity and Type 2 Diabetes”
by Federica Zatterale, Gregory Alexander Raciti, Immacolata Prevenzano, Alessia Leone, Michele Campitelli, Veronica De Rosa, Francesco Beguinot and Luca Parrillo
Biomolecules 202212(7), 982; https://doi.org/10.3390/biom12070982
Full text available online: https://www.mdpi.com/2218-273X/12/7/982

10. “Grapevine DMR6-1 Is a Candidate Gene for Susceptibility to Downy Mildew”
by Carlotta Pirrello, Giulia Malacarne, Marco Moretto, Luisa Lenzi, Michele Perazzolli, Tieme Zeilmaker, Guido Van den Ackerveken, Stefania Pilati, Claudio Moser and Lisa Giacomelli
Biomolecules 2022, 12(2), 182; https://doi.org/10.3390/biom12020182
Full text available online: https://www.mdpi.com/2218-273X/12/2/182

10 September 2024
Biomolecules | Highly Cited Papers in 2022–2023 in the Section “Molecular Medicine”


As all of the articles published in our journal are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below.

1. “NAFLD: Mechanisms, Treatments, and Biomarkers”
by Fatiha Nassir
Biomolecules 2022, 12(6), 824; https://doi.org/10.3390/biom12060824
Full text available online: https://www.mdpi.com/2218-273X/12/6/824

2. “Nano-Based Approved Pharmaceuticals for Cancer Treatment: Present and Future Challenges”
by Francisco Rodríguez, Pablo Caruana, Noa De la Fuente, Pía Español, María Gámez, Josep Balart, Elisa Llurba, Ramón Rovira, Raúl Ruiz, Cristina Martín-Lorente et al.
Biomolecules202212(6), 784; https://doi.org/10.3390/biom12060784
Full text available online: https://www.mdpi.com/2218-273X/12/6/784

3. “Biological Effects of Human Exposure to Environmental Cadmium”
by Massimiliano Peana, Alessio Pelucelli, Christos T. Chasapis, Spyros P. Perlepes, Vlasoula Bekiari, Serenella Medici and Maria Antonietta Zoroddu 
Biomolecules2023,13(1), 36; https://doi.org/10.3390/biom13010036
Full text available online: https://www.mdpi.com/2218-273X/13/1/36

4. “Oxidative Stress and NRF2/KEAP1/ARE Pathway in Diabetic Kidney Disease (DKD): New Perspectives”
by Daniela Maria Tanase, Evelina Maria Gosav, Madalina Ioana Anton, Mariana Floria, Petronela Nicoleta Seritean Isac, Loredana Liliana Hurjui, Claudia Cristina Tarniceriu, Claudia Florida Costea, Manuela Ciocoiu and Ciprian Rezus 
Biomolecules202212(9), 1227; https://doi.org/10.3390/biom12091227
Full text available online: https://www.mdpi.com/2218-273X/12/9/1227

5. “The Role of Tryptophan Dysmetabolism and Quinolinic Acid in Depressive and Neurodegenerative Diseases”
by Knut Hestad, Jan Alexander, Helge Rootwelt and Jan O. Aaseth 
Biomolecules202212(7), 998; https://doi.org/10.3390/biom12070998
Full text available online: https://www.mdpi.com/2218-273X/12/7/998

6. “Recent Advances of Tubulin Inhibitors Targeting the Colchicine Binding Site for Cancer Therapy”
by Mohammed Hawash 
Biomolecules202212(12), 1843; https://doi.org/10.3390/biom12121843
Full text available online: https://www.mdpi.com/2218-273X/12/12/1843

7. “Cerebral Iron Deposition in Neurodegeneration”
by Petr Dusek, Tim Hofer, Jan Alexander, Per M. Roos and Jan O. Aaseth 
Biomolecules202212(5), 714; https://doi.org/10.3390/biom12050714
Full text available online: https://www.mdpi.com/2218-273X/12/5/714

8. “Progesterone as an Anti-Inflammatory Drug and Immunomodulator: New Aspects in Hormonal Regulation of the Inflammation”
by Tatiana A. Fedotcheva, Nadezhda I. Fedotcheva and Nikolai L. Shimanovsky
Biomolecules202212(9), 1299; https://doi.org/10.3390/biom12091299
Full text available online: https://www.mdpi.com/2218-273X/12/9/1299

9. “The Impact of Zinc and Zinc Homeostasis on the Intestinal Mucosal Barrier and Intestinal Diseases”
by Yan Wan and Bingkun Zhang 
Biomolecules202212(7), 900; https://doi.org/10.3390/biom12070900
Full text available online: https://www.mdpi.com/2218-273X/12/7/900

10. “The Role of JAK/STAT Pathway in Fibrotic Diseases: Molecular and Cellular Mechanisms”
by Jia Liu, Faping Wang and Fengming Luo 
Biomolecules202313(1), 119; https://doi.org/10.3390/biom13010119
Full text available online: https://www.mdpi.com/2218-273X/13/1/119

10 September 2024
Meet Us at the 2024 International Conference of the Korean Society for Molecular and Cellular Biology, 8–11 October 2024, Jeju, Republic of Korea


The 2024 International Conference of the Korean Society for Molecular and Cellular Biology will be held from 8 to 11 October 2024, in Jeju, Republic of Korea. The conference is organized by the Korean Society for Molecular and Cellular Biology, and promises a rich tapestry of scholarly exchange across various disciplines within biological and biomedical sciences.

The conference will feature four top keynote speakers in the field of life sciences, including two Nobel Prize winners, and scientists from more than thirty countries around the world participating in more than twenty scientific sessions on a variety of topics. The agenda includes symposiums showcasing pioneering research in life sciences, dedicated sessions for young academics, such as graduate students, postdoctoral researchers, and research professors, and a Bio Job Fair.

The following MDPI journals will be represented at the conference:

  • International Journal of Molecular Sciences;
  • Antioxidants;
  • Biophysica;
  • Current Issues in Molecular Biology;
  • Kinases and Phosphatases;
  • Metabolites;
  • Microorganisms;
  • Proteomes;
  • Bioengineering;
  • Biomedicines;
  • BioMed;
  • Biomolecules;
  • Cancers;
  • Genes;
  • Journal of Molecular Pathology;
  • Organoids;
  • Plants;
  • Non-Coding RNA;
  • Sci;
  • Journal of Fungi.

If you are attending this conference, please feel free to start an online conversation with us. Our delegates look forward to meeting you in person at booth #99 and answering any questions that you may have. For more information about the conference, please visit the following link: https://www.ksmcb.or.kr/icksmcb2024/main.html.

3 September 2024
MDPI INSIGHTS: The CEO's Letter #15 - CHORUS, Best Paper Award, August Events

Welcome to the MDPI Insights: The CEO's Letter.

In these monthly letters, I will showcase two key aspects of our work at MDPI: our commitment to empowering researchers and our determination to facilitating open scientific exchange.


Opening Thoughts

I am pleased to share that MDPI is now an Affiliate Member of CHORUS, a not-for-profit organization dedicated to ensuring public access to articles reporting on U.S. government-funded research. This partnership highlights our long-standing commitment to advancing Open Access (OA) publishing and meeting funders’ open research requirements.

Read the full announcement here.

With the White House Office of Science and Technology Policy (OSTP) 2022 memorandum calling for immediate public access to all federally funded research by 2026, this partnership positions MDPI to further support academic institutions in adhering to national mandates while providing authors with fully compliant (CC-BY) OA journals.

The CHORUS platform went live in July 2014 and includes NASA, the U.S. Department of Energy, the U.S. Department of Defense, the U.S. Geological Survey, and the National Science Foundation.

“This partnership positions MDPI to further support academic institutions in adhering to national mandates”

Joining CHORUS perfectly aligns our mission as the leading OA publisher, which is to drive transparency and innovation in scholarly publishing, with that of CHORUS itself, which is to advance Open Access research. It will also support MDPI publications from organizations such as NASA, with 1,200 research papers published by NASA-affiliated authors as at 31 August 2024.

Impactful Research

MDPI’s Best Paper Awards—Award-Winning Papers in 2023 Announced

MDPI is committed to supporting and recognizing the academic community and is proud to announce the recipients of the 2023 Best Paper Awards, which recognize high-quality papers of significant scientific merit and impact. Each year, the editors of our journals carefully select papers that showcase outstanding scientific achievement.

This year, 115 Best Paper Awards were presented, chosen from 346 exceptional papers in a highly competitive selection process. Congratulations to the authors for their remarkable contributions!

To learn more about all the awardees and their research projects, visit the following pages:

About MDPI Awards
MDPI regularly offers various awards to recognize researchers, particularly young scientists, and to promote communication within the scientific community. These awards exist to inspire and acknowledge talented scientists who have made significant contributions to advancing their fields.

To find out more MDPI awards, please click here.

“Our awards exist to inspire and acknowledge talented scientists”

Inside MDPI

MDPI AI Team Presented at EuroSciPy 2024 in Poland

As part of the CEO Letter, I hold dear this ‘Inside MDPI’ section, where I have an opportunity to highlight various projects, teams and updates within our organization. As such, I’m happy to showcase the following presentations from members of MDPI’s Artificial Intelligence (AI) team, which were recently presented at the EuroSciPy 2024 (16th European Conference on Python in Science). This conference took place in Szczecin, Poland from 26–30 August.

“This event was a great opportunity to reinforce our commitment to innovation and excellence in publishing”

MDPI colleagues Frank Sauerburger (AI Tech Leader) and Daniele Raimondi (Senior Data Scientist) both presented at the conference. Frank discussed MDPI’s AI infrastructure, while Daniele showcased a new methodological approach we have been developing to track the journey of rejected academic manuscripts. This approach combines AI, data science and analytics to improve the identification of manuscripts and authors, enhancing our understanding of publishing dynamics.

This event was a great opportunity to reinforce our commitment to innovation and excellence in publishing. It also allowed us to contribute to the academic discussion on integrating AI and data science into scholarly communication.

From data analysis in Jupyter Notebooks to production applications: AI infrastructure at reasonable scale – Frank Sauerburger

Frank’s presentation on MDPI’s AI infrastructure provided a chance to showcase the advanced technological frameworks that power our operations. Given the technical and academic focus of EuroSciPy, this talk demonstrated how MDPI’s AI capabilities are not only cutting-edge but also central to driving efficiency and innovation in scholarly publishing. Engaging with the EuroSciPy community helps position MDPI as a leader in applying AI within the publishing industry, fostering potential collaborations and attracting interest from top researchers.

A Qdrant and Specter2 framework for tracking resubmissions of rejected manuscripts in academia – Daniele Raimondi

Daniele’s talk on the novel methodological approach that combines AI, Data Science, and Analytics was crucial in highlighting how MDPI is advancing the precision and effectiveness of manuscript and author identification. This approach is pivotal in enhancing our understanding of publishing dynamics and ensuring the quality and integrity of the academic content we manage. By presenting at EuroSciPy, we had the opportunity to engage with an audience deeply involved in scientific computing, gaining feedback and insights that could further refine our methodologies.

Thank you, Frank and Daniele, for representing MDPI so well!

I will share more about MDPI’s AI team and projects in upcoming CEO Letters, as we have a well-rounded AI and Data Team working on an exciting suite of AI products for MDPI and the scholarly community at large.

Coming Together for Science

The 1st International Conference on AI Sensors & The 10th International Symposium on Sensor Science

I am pleased to share the success of our MDPI conference The 1st International Conference on Artificial Intelligence (AI) Sensors and the 10th International Symposium on Sensor Science in Singapore this past 1–4 August.

With nearly 400 attendees, the event brought together researchers and industry experts from China, Singapore, Japan, Korea, Taiwan, India and other countries to share their findings on the latest developments in sensors, sensing technology, artificial intelligence for sensing applications and AI-enhanced sensing systems.

We accepted a total of 355 abstracts, featuring 772 authors from 28 countries. Over the course of the four-day event, 66 posters were displayed and 296 talks were delivered, including 4 plenary talks, 46 keynote speeches, 122 invited talks, and 124 selected oral presentations. View the event gallery here.

I am pleased to announce the winners of the four awards, including Best Presentation and Best Poster, recognizing the contributions of our participants during the conference.

Looking ahead, the 2nd International Conference on AI Sensors and Transducers is scheduled to take place from 29 July to 5 August, 2025, in Bangkok, Thailand.

Thank you to our Conference team, including Ionut Spatar, Teodora Nicoleta Cremene, Ang Kai Lin, Benjamin Tay, Leong Jin Yue Esther, Wong Jolin, Judith Wu, Alethea Liu and Flora Li, who were involved in making this event a success. A big thank-you also goes to our local MDPI colleagues for their support: Yu Nwe Soe, Hen Chu Yang, Kwah Zhi En Watcharapong, Zephan Yang, Daphne Neo, Huimin Cheng, Nathan Li and Ting Yin.

Upcoming In-Person Event

25–27 September, 2024
The 5th International Conference on Materials: Advances in Material Innovation
Location: Basel, Switzerland

ICM 2024 will unite experts to share insights on recent advancements in Materials Characterization, Processing and Manufacturing.

7–9 October, 2024
Non-coding RNA World 2024: Exploring Mechanisms, Designing Medicines
Location: Basel, Switzerland

ncRNA 2024 will explore the latest advances in the field, covering topics from basic biology to medical and technological applications.

Find more upcoming MDPI events here.

Closing Thoughts

The 2nd Sustainable Publishing Forum

In 2022, the International Association of Scientific, Technical and Medical Publishers (STM) outlined three goals to reflect the academic community’s shared aspirations: promoting Open Science, maintaining research integrity and fulfilling social responsibility. Open Science has evolved from the Open Access movement of the early 2000s to become a preferred model in academic publishing. Publishers and academic journals play a crucial role in ensuring research integrity, with efforts to prevent misconduct markedly on the increase now.

As the world faces sustainability challenges, the academic publishing industry is increasingly committed to contributing the achievement of the United Nations Sustainable Development Goals (SDGs). Many publishers are implementing strategies to support these objectives, including ours, which you can view here.

The 2nd MDPI Sustainable Publishing Forum provided a platform for global editors and publishers to discuss these themes, aiming to strengthen collaboration and advance the contributions that scientific publishing can make to academia and society.

“Open Science has evolved to become a preferred model in academic publishing”

The 2nd Sustainable Publishing Forum

We hosted MDPI’s 2nd Sustainable Publishing Forum in Beijing, China, on 15–16 August, attracting nearly 120 attendees from local and international publishers, university presses, scientific and technical journal associations, libraries and the Chinese Academy of Sciences. The event focused on promoting Open Science, maintaining research integrity, and fulfilling social responsibility.

This was an excellent opportunity for us to share more with conference attendees about the approach of our research integrity team. Our Head of Publishing, Peter Roth, also participated, speaking on how to identify and avoid predatory publishers and about the principles that underpin ethical academic publishing.

I extend my thanks to all of our conference speakers, including Hylke Koers (STM Solutions), who presented on STM Trends 2028 and shared insights on the STM Integrity Hub, of which MDPI is a member.

Stefan Tochev
Chief Executive Officer
MDPI AG

19 August 2024
MDPI’s 2023 Young Investigator Awards—Winners Announced


MDPI’s Young Investigator Awards recognize promising early career scientists, acknowledge their contributions, and foster collaboration within the scientific community. We are proud to announce the recipients for 2023, who were carefully selected by the journals’ esteemed Award Evaluation Committee.

We extend our heartfelt congratulations to the 79 winners of MDPI’s 2023 Young Investigator Awards for their excellent contributions in their research field. We look forward to seeing these rising stars continue to contribute to the advancement of science.

MDPI will continue to support and recognize the academic community. To explore details about the awardees by field, please visit the individual pages listed below:

Congratulations to all the winners for their exceptional contributions and dedication to advancing scientific research.

About MDPI Awards:
To support the academic community, particularly young researchers, and to enhance communication among scientists, MDPI journals regularly offer various awards to researchers in specific fields. These awards, serving as a source of inspiration and recognition, help to elevate the profiles of talented individuals who have made outstanding achievements and are making significant contributions to advancements in their respective fields.

To find out more about MDPI awards, please click here.

16 August 2024
Biomolecules | Highly Cited Papers in 2022–2023 in the Section “Biological and Bio-Materials”


As all of the articles published in our journal Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below:

1. “Development of Biodegradable Polymeric Stents for the Treatment of Cardiovascular Diseases”
by Yihong Shen, Xiao Yu, Jie Cui, Fan Yu, Mingyue Liu, Yujie Chen, Jinglei Wu, Binbin Sun and Xiumei Mo
Biomolecules 2022, 12(9), 1245; https://doi.org/10.3390/biom12091245
Full text available online: https://www.mdpi.com/2218-273X/12/9/1245

2. “Advances in the Application of Electrospun Drug-Loaded Nanofibers in the Treatment of Oral Ulcers”
by Yangqi Zhou, Menglong Wang, Chao Yan, Hui Liu and Deng-Guang Yu
Biomolecules 2022, 12(9), 1254; https://doi.org/10.3390/biom12091254
Full text available online: https://www.mdpi.com/2218-273X/12/9/1254

3. ”Design of Biocompatible Chitosan/Polyaniline/Laponite Hydrogel with Photothermal Conversion Capability”
by Liying Zhang, Gao He, Yang Yu, Yu Zhang, Xiang Li and Shige Wang
Biomolecules 2022, 12(8), 1089; https://doi.org/10.3390/biom12081089
Full text available online: https://www.mdpi.com/2218-273X/12/8/1089

4. A Review on Electrospun Poly(amino acid) Nanofibers and Their Applications of Hemostasis and Wound Healing
by Yuexin Ji, Wenliang Song, Lin Xu, Deng-Guang Yu and Sim Wan Annie Bligh
Biomolecules 2022, 12(6), 794; https://doi.org/10.3390/biom12060794
Full text available online: https://www.mdpi.com/2218-273X/12/6/794

5. Silk Fibroin Biomaterials and Their Beneficial Role in Skin Wound Healing
by Łukasz Mazurek, Mateusz Szudzik, Mateusz Rybka and Marek Konop
Biomolecules 2022, 12(12), 1852; https://doi.org/10.3390/biom12121852
Full text available online: https://www.mdpi.com/2218-273X/12/12/1852

6. Recent Developments in Biopolymer-Based Hydrogels for Tissue Engineering Applications
by Rikako Hama, Anudari Ulziibayar, James W. Reinhardt, Tatsuya Watanabe, John Kelly and Toshiharu Shinoka
Biomolecules 2023, 13(2), 280; https://doi.org/10.3390/biom13020280
Full text available online: https://www.mdpi.com/2218-273X/13/2/280

7. Electrospun Zein/Polyoxyethylene Core-Sheath Ultrathin Fibers and Their Antibacterial Food Packaging Applications
by Wenlai Jiang, Ping Zhao, Wenliang Song, Menglong Wang and Deng-Guang Yu
Biomolecules 2022, 12(8), 1110; https://doi.org/10.3390/biom12081110
Full text available online: https://www.mdpi.com/2218-273X/12/8/1110

8. Advances in the Preparation of Nanofiber Dressings by Electrospinning for Promoting Diabetic Wound Healing
by Yukang Liu, Chaofei Li, Zhangbin Feng, Biao Han, Deng-Guang Yu and Ke Wang
Biomolecules 2022, 12(12), 1727; https://doi.org/10.3390/biom12121727
Full text available online: https://www.mdpi.com/2218-273X/12/12/1727

9. Recent Progress of Electrospun Herbal Medicine Nanofibers
by Hang Liu, Yubin Bai, Chang Huang, Ying Wang, Yuexin Ji, Yutong Du, Lin Xu, Deng-Guang Yu and Sim Wan Annie Bligh
Biomolecules 2023, 13(1), 184; https://doi.org/10.3390/biom13010184
Full text available online: https://www.mdpi.com/2218-273X/13/1/184

10. Advancements in Fabrication and Application of Chitosan Composites in Implants and Dentistry: A Review
by Fariborz Sharifianjazi, Samad Khaksar, Amirhossein Esmaeilkhanian, Leila Bazli, Sara Eskandarinezhad, Peyman Salahshour, Farnaz Sadeghi, Sadegh Rostamnia and Seyed Mohammad Vahdat
Biomolecules 2022, 12(2), 155; https://doi.org/10.3390/biom12020155
Full text available online: https://www.mdpi.com/2218-273X/12/2/155

16 August 2024
Biomolecules | Highly Cited Papers in 2022–2023 in the Section “Biological Factors”


As all of the articles published in our journal Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below:

1. “The Degradation of Hyaluronan in the Skin”
by Petra Žádníková, Romana Šínová, Vojtěch Pavlík, Matěj Šimek, Barbora Šafránková, Martina Hermannová, Kristina Nešporová and Vladimír Velebný
Biomolecules 2022, 12(2), 251; https://doi.org/10.3390/biom12020251
Full text available online: https://www.mdpi.com/2218-273X/12/2/251

2. “Role of EPA in Inflammation: Mechanisms, Effects, and Clinical Relevance”
by Rosalia Crupi and Salvatore Cuzzocrea
Biomolecules 2022, 12(2), 242; https://doi.org/10.3390/biom12020242
Full text available online: https://www.mdpi.com/2218-273X/12/2/242

3. “The Effect of Electrical Stimulation on Nerve Regeneration Following Peripheral Nerve Injury”
by Luke Juckett, Tiam Mana Saffari, Benjamin Ormseth, Jenna-Lynn Senger and Amy M. Moore
Biomolecules 2022, 12(12), 1856; https://doi.org/10.3390/biom12121856
Full text available online: https://www.mdpi.com/2218-273X/12/12/1856

4. “Homocysteine, Vitamins B6 and Folic Acid in Experimental Models of Myocardial Infarction and Heart Failure—How Strong Is That Link?”
by Zorislava Bajic, Tanja Sobot, Ranko Skrbic, Milos P. Stojiljkovic, Nenad Ponorac, Amela Matavulj  and Dragan M. Djuric
Biomolecules 2022, 12(4), 536; https://doi.org/10.3390/biom12040536
Full text available online: https://www.mdpi.com/2218-273X/12/4/536

5. “Advanced Strategies for Therapeutic Targeting of Wild-Type and Mutant p53 in Cancer”
by Shengliang Zhang, Lindsey Carlsen, Liz Hernandez Borrero, Attila A. Seyhan, Xiaobing Tian and Wafik S. El-Deiry
Biomolecules 2022, 12(4), 548; https://doi.org/10.3390/biom12040548
Full text available online: https://www.mdpi.com/2218-273X/12/4/548

6. “Louis Pasteur: Between Myth and Reality”
by Jean-Marc Cavaillon and Sandra Legout
Biomolecules 2022, 12(4), 596; https://doi.org/10.3390/biom12040596
Full text available online: https://www.mdpi.com/2218-273X/12/4/596

7. “Delayed Onset Muscle Soreness and Critical Neural Microdamage-Derived Neuroinflammation”
by Balázs Sonkodi
Biomolecules 2022, 12(9), 1207; https://doi.org/10.3390/biom12091207
Full text available online: https://www.mdpi.com/2218-273X/12/9/1207

8. “The Challenges and Prospects of p53-Based Therapies in Ovarian Cancer”
by Bryce Wallis, Katherine Redd Bowman, Phong Lu and Carol S. Lim
Biomolecules 2023, 13(1), 159; https://doi.org/10.3390/biom13010159
Full text available online: https://www.mdpi.com/2218-273X/13/1/159

9. “Cross-Talk between p53 and Wnt Signaling in Cancer”
by Qiyun Xiao, Johannes Werner, Nachiyappan Venkatachalam, Kim E. Boonekamp, Matthias P. Ebert and Tianzuo Zhan
Biomolecules 2022, 12(3), 453; https://doi.org/10.3390/biom12030453
Full text available online: https://www.mdpi.com/2218-273X/12/3/453

10. “Nitrogen Journey in Plants: From Uptake to Metabolism, Stress Response, and Microbe Interaction”
by Omar Zayed, Omar A. Hewedy, Ali Abdelmoteleb, Mohammed, Mohamed S. Youssef, Ahmed F. Roumia, Danelle Seymour and Ze-Chun Yuan
Biomolecules 2023, 13(10), 1443; https://doi.org/10.3390/biom13101443
Full text available online: https://www.mdpi.com/2218-273X/13/10/1443

16 August 2024
Biomolecules | Highly Cited Papers in 2022–2023 in the Section “Cellular Biochemistry”


As all of the articles published in our journal Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full texts. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below:

1. Advanced Glycation End Products and Diabetes Mellitus: Mechanisms and Perspectives”
by Mariyam Khalid, Georg Petroianu and Abdu Adem
Biomolecules 2022, 12(4), 542; https://doi.org/10.3390/biom12040542
Full text available online: https://www.mdpi.com/2218-273X/12/4/542

2. “Metallothionein and Cadmium Toxicology—Historical Review and Commentary”
by Monica Nordberg and Gunnar F. Nordberg
Biomolecules 2022, 12(3), 360; https://doi.org/10.3390/biom12030360
Full text available online: https://www.mdpi.com/2218-273X/12/3/360

3. “Adenosine-Metabolizing Enzymes, Adenosine Kinase and Adenosine Deaminase, in Cancer”
by Galina Zhulai, Eugenia Oleinik, Mikhail Shibaev and Kirill Ignatev
Biomolecules 2022, 12(3), 418; https://doi.org/10.3390/biom12030418
Full text available online: https://www.mdpi.com/2218-273X/12/3/418

4. “Current and Novel Therapeutic Approaches for Treatment of Neovascular Age-Related Macular Degeneration”
by Reem H. ElSheikh, Muhammad Z. Chauhan and Ahmed B. Sallam
Biomolecules 2022, 12(11), 1629; https://doi.org/10.3390/biom12111629
Full text available online: https://www.mdpi.com/2218-273X/12/11/1629

5. “Bcl-2 Family Members and the Mitochondrial Import Machineries: The Roads to Death”
by Lisenn Lalier, François Vallette François Vallette and Stéphen Manon
Biomolecules 2022, 12(2), 162; https://doi.org/10.3390/biom12020162
Full text available online: https://www.mdpi.com/2218-273X/12/2/162

6. “The Disordered Dehydrin and Its Role in Plant Protection: A Biochemical Perspective”
by Margaret A. Smith and Steffen P. Graether
Biomolecules 2022, 12(2), 294; https://doi.org/10.3390/biom12020294
Full text available online: https://www.mdpi.com/2218-273X/12/2/294

7. “Co-Stimulatory Receptor Signaling in CAR-T Cells”
by Mackenzie M. Honikel and Scott H. Olejniczak
Biomolecules 2022, 12(9), 1303; https://doi.org/10.3390/biom12091303
Full text available online: https://www.mdpi.com/2218-273X/12/9/1303

8. “Galactosemia: Biochemistry, Molecular Genetics, Newborn Screening, and Treatment”
by Mariangela Succoio, Rosa Sacchettini, Alessandro Rossi, Giancarlo Parenti and Margherita Ruoppolo
Biomolecules 2022, 12(7), 968; https://doi.org/10.3390/biom12070968
Full text available online: https://www.mdpi.com/2218-273X/12/7/968

9. “Molecular Recognition of Proteins through Quantitative Force Maps at Single Molecule Level”
by Carlos Marcuello, Rocío de Miguel and Anabel Lostao
Biomolecules 2022, 12(4), 594; https://doi.org/10.3390/biom12040594
Full text available online: https://www.mdpi.com/2218-273X/12/4/594

10. “Cellular Senescence in Intervertebral Disc Aging and Degeneration: Molecular Mechanisms and Potential Therapeutic Opportunities”
by Prashanta Silwal, Allison M. Nguyen-Thai, Haneef Ahamed Mohammad, Yanshan Wang, Paul D. Robbins, Joon Y. Lee and Nam V. Vo
Biomolecules 2023, 13(4), 686; https://doi.org/10.3390/biom13040686
Full text available online: https://www.mdpi.com/2218-273X/13/4/686

15 August 2024
Biomolecules | Highly Cited Papers in 2022–2023 in the Section “Bioinformatics and Systems Biology”


As all of the articles published in our journal Biomolecules (ISSN: 2218-273X) are open access, you have free and unlimited access to the full text. We welcome you to read our most highly cited papers published in 2022 and 2023, which are listed below:

1. “Boosting the Full Potential of PyMOL with Structural Biology Plugins”
by Serena Rosignoli and Alessandro Paiardini
Biomolecules 2022, 12(12), 1764; https://doi.org/10.3390/biom12121764
Full text available online: https://www.mdpi.com/2218-273X/12/12/1764

2. “Calcium Overload and Mitochondrial Metabolism”
by Lauren L. Walkon, Jasiel O. Strubbe-Rivera and Jason N. Bazil
Biomolecules 2022, 12(12), 1891; https://doi.org/10.3390/biom12121891
Full text available online: https://www.mdpi.com/2218-273X/12/12/1891

3. “Benchmarking the Accuracy of AlphaFold 2 in Loop Structure Prediction”
by Amy O. Stevens and Yi He
Biomolecules 2022, 12(7), 985; https://doi.org/10.3390/biom12070985
Full text available online: https://www.mdpi.com/2218-273X/12/7/985

4. “Protein Data Bank: A Comprehensive Review of 3D Structure Holdings and Worldwide Utilization by Researchers, Educators, and Students”
by Stephen K. Burley, Helen M. Berman, Jose M. Duarte, Zukang Feng, Justin W. Flatt, Brian P. Hudson, Robert Lowe, Ezra Peisach, Dennis W. Piehl, Yana Rose et al.
Biomolecules 2022, 12(10), 1425; https://doi.org/10.3390/biom12101425
Full text available online: https://www.mdpi.com/2218-273X/12/10/1425

5. “Predicting miRNA-Disease Association Based on Neural Inductive Matrix Completion with Graph Autoencoders and Self-Attention Mechanism”
by Chen Jin, Zhuangwei Shi, Ken Lin and Han Zhang
Biomolecules 2022, 12(1), 64; https://doi.org/10.3390/biom12010064
Full text available online: https://www.mdpi.com/2218-273X/12/1/64

6. “ECMpy, a Simplified Workflow for Constructing Enzymatic Constrained Metabolic Network Model”
by Zhitao Mao, Xin Zhao, Xue Yang, Peiji Zhang, Jiawei Du, Qianqian Yuan and Hongwu Ma
Biomolecules 2022, 12(1), 65; https://doi.org/10.3390/biom12010065
Full text available online: https://www.mdpi.com/2218-273X/12/1/65

7. “The Epigenetic Dimension of Protein Structure Is an Intrinsic Weakness of the AlphaFold Program”
by Fodil Azzaz, Nouara Yahi, Henri Chahinianand Jacques Fantini
Biomolecules 2022, 12(10), 1527; https://doi.org/10.3390/biom12101527
Full text available online: https://www.mdpi.com/2218-273X/12/10/1527

8. “The Metabolomic Approach for the Screening of Endometrial Cancer: Validation from a Large Cohort of Women Scheduled for Gynecological Surgery”
by Jacopo Troisi, Antonio Mollo, Martina Lombardi, Giovanni Scala, Sean M. Richards, Steven J. K. Symes, Antonio Travaglino, Daniele Neola, Umberto de Laurentiis, Luigi Insabato et al.
Biomolecules 2022, 12(9), 1229; https://doi.org/10.3390/biom12091229
Full text available online: https://www.mdpi.com/2218-273X/12/9/1229

9. “Saquinavir: From HIV to COVID-19 and Cancer Treatment”
by Mariana Pereira and Nuno Vale
Biomolecules 2022, 12(7), 944; https://doi.org/10.3390/biom12070944
Full text available online: https://www.mdpi.com/2218-273X/12/7/944

10. “Bioinformatics Prediction and Experimental Validation Identify a Novel Cuproptosis-Related Gene Signature in Human Synovial Inflammation during Osteoarthritis Progression”
by Wenjuan Wang, Ziyi Chen and Yinghui Hua
Biomolecules 2023, 13(1), 127; https://doi.org/10.3390/biom13010127
Full text available online: https://www.mdpi.com/2218-273X/13/1/127

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