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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Agri-Food Waste Extracts: Structural and Functional Characterization

edited by

Stefania Lamponi

submission deadline 12 Jun 2026 | 1 articles | Viewed by 2301 | Submission Open

Keywords: agri-food waste; extracts; extraction techniques; chemical characterization; bioactivity; cytotoxicity and cytocompatibility; isolation of bioactive molecules

(This special issue belongs to the Section Plant Science)

Ultrasound and Anatomical Studies

edited by

Maribel Miguel-Pérez

, Ingrid Moller and

Albert Pérez-Bellmunt

submission deadline 15 Jun 2026 | 1 articles | Viewed by 688 | Submission Open

Keywords: ultrasound techniques; musculoskeletal system; human anatomy; medicine specialties; clinical students; ultrasound teaching

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Epigenetics, Microbiota, and Food—Shaping Immune Health and Longevity

edited by

Berit Hippe

submission deadline 18 Jun 2026 | 3 articles | Viewed by 11993 | Submission Open

Keywords: epigenetics; nutrigenomics; aging; microRNA; DNA methylation; diet; nutrients; microbiota; longevity; natural components

(This special issue belongs to the Section Physiology and Pathology)

Advances in Research on Motor Deficits Caused by Neurological Disorders: From Mechanism to Treatment

edited by

Mengliang Zhang

and Hans Hultborn

submission deadline 18 Jun 2026 | 3 articles | Viewed by 8736 | Submission Open

Keywords: neurological disorders; neurodegenerative diseases; brain injury; spinal cord injury; stroke; cerebral palsy; peripheral nerve injury; paralysis; spasticity; contracture; muscle weakness; postural asymmetry; gate pattern changes; uncontrolled movements

(This special issue belongs to the Section Medical Research)

Dive into Myopia

edited by

Chun-Fu Liu

submission deadline 19 Jun 2026 | 4 articles | Viewed by 9916 | Submission Open

Keywords: myopia; hyperopia; myopia control; axial length; axial length retardation; axial length elongation; myopia complications; refraction measurement; atropine; rebound effect; orthokeratology; missight; defocus incorporated multiple segments (DIMSs); highly aspherical lenslets (HALs); red light; repeated low-level red light (RLRL) therapy; enhance myopia control; customized myopia control; peripheral refraction; peripheral myopia; refractive surgery; PRK; LASIK; smile; contact lens; spectacles

(This special issue belongs to the Section Medical Research)

Lipid Metabolism Pathways: From Life to Disease

edited by

Anna Eiring

submission deadline 19 Jun 2026 | 2 articles | Viewed by 8651 | Submission Open

Keywords: lipid metabolism; lipid signaling; apoptosis; ferroptosis; autophagy; membrane dynamics; fatty acid oxidation; obesity

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

An Integrated Approach on Diagnosis and Treatment of Cerebral Veins and Intracranial Dural Sinuses Thrombosis (CVT)

edited by

Dragos Catalin Jianu

and

Dafin Fior Muresanu

submission deadline 20 Jun 2026 | 1 articles | Viewed by 585 | Submission Open

Keywords: cerebral veins and intracranial dural sinuses thrombosis (CVT); thrombophilia; intracranial hypertension; non-enhanced computer tomography (NECT) of the head; computer tomography venography (CTV); magnetic resonance imaging (MRI) of the head; magnetic resonance venography (MRV); anticoagulation

(This special issue belongs to the Section Medical Research)

Advances in Knee Biomechanics—2nd Edition

edited by Jason Shearn

submission deadline 22 Jun 2026 | Viewed by 240 | Submission Open

Keywords: knee; tendon; ligament; injury; repair; healing; biomechanics; advanced techniques

(This special issue belongs to the Section Physiology and Pathology)

Reconstruction of Bone Defects

edited by

Jörg Eschweiler

and

Philipp Kobbe

submission deadline 23 Jun 2026 | 10 articles | Viewed by 15089 | Submission Open

Keywords: bone and fracture biomechanics; bone healing; critical size bone defects; fracture non-union; inflammation; joint arthroplasty and fracture osteosynthesis; implant designs; materials proprieties; patient selection; primary and revision settings

(This special issue belongs to the Section Medical Research)

Recent Advances in Vascular Biology and Chronic Kidney Disease (CKD)

edited by

Yongseek Park

submission deadline 26 Jun 2026 | 2 articles | Viewed by 9952 | Submission Open

Keywords: chronic kidney disease; vascular dysfunction; endothelial cells

(This special issue belongs to the Section Medical Research)

Advances in Anesthesia and Critical Care

edited by

Gabriele Melegari

submission deadline 26 Jun 2026 | 5 articles | Viewed by 9886 | Submission Open

Keywords: anesthesia; intensive care training; updates in anesthesia; machine learning

(This special issue belongs to the Section Medical Research)

Advances in Dryland Agriculture Science

edited by

Liangshan Feng

and Hangyu Dong

submission deadline 26 Jun 2026 | 3 articles | Viewed by 5478 | Submission Open

Keywords: dry farming; climate smart agriculture; soil and water protection; conservation tillage; intercropping; crop rotation; saving irrigation

(This special issue belongs to the Section Plant Science)

Feature Papers in Medical Research: 4th Edition

edited by

Christian Lehmann

submission deadline 26 Jun 2026 | 6 articles | Viewed by 5137 | Submission Open

Keywords: dermatological research; cancer research; cardiovascular research; general medicine; gastroenterological research; hematological research; immunological research; infectious diseases research; metabolism and endocrinology; nervous system research; nursing; pediatrics; pulmonary research; psychiatric research; rehabilitation; renal and urinary research; reproductive research and women's health; rheumatological research; skeletal and muscular research; vision research

(This special issue belongs to the Section Medical Research)

Advanced Technologies and Clinical Practice of Cancer Radiotherapy

edited by

Marcin Balcerzyk

submission deadline 26 Jun 2026 | 1 articles | Viewed by 1279 | Submission Open

Keywords: proton therapy; BNCT; in vivo dose verification in radiotherapy; accelerators for radiation therapy; simulation of radiotherapies

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Innovations in Thoracic Medicine: Advancements and Challenges—2nd Edition

edited by Paolo Scanagatta

submission deadline 26 Jun 2026 | 1 articles | Viewed by 1151 | Submission Open

Keywords: thoracic medicine; lung cancer; artificial intelligence (AI); minimally invasive intervention; thoracic anesthesia; clinical innovation; technological advances

(This special issue belongs to the Section Medical Research)

Application of Mass Spectrometry-Based Multi-Omics in Biomedical Research

edited by

Young Ah Goo

and

Byoung-Kyu Cho

submission deadline 26 Jun 2026 | 1 articles | Viewed by 792 | Submission Open

Keywords: mass spectrometry; multi-omics; proteomics; metabolomics; lipidomics; mass spectrometry imaging (MSI); biomarker discovery; translational research

(This special issue belongs to the Section Medical Research)

Harnessing Mitochondrial Rewiring for Cancer Therapy: Novel Strategies in the Era of Precision Medicine

edited by

Theodoros Rampias

and Maria Sideridou

submission deadline 26 Jun 2026 | Viewed by 318 | Submission Open

Keywords: Oxidative stress; Metabolic rewiring; Carcinogenesis; DNA repair; Cancer therapy; Heteroplasmy

(This special issue belongs to the Section Physiology and Pathology)

Leveraging the Power of Enzymes in Biotechnological Applications

edited by

Shengwei Sun

submission deadline 28 Jun 2026 | Viewed by 631 | Submission Open

Keywords: enzyme; 3D structure; function/activity; enzyme engineering; beneficial variants; industrial application

Effects of Exercise and Functional Interventions on Musculoskeletal Health

edited by

Seong-Gil Kim

submission deadline 30 Jun 2026 | 10 articles | Viewed by 28900 | Submission Open

Keywords: musculoskeletal health; exercise; physical function; joint stability; fall prevention; rehabilitation science

(This special issue belongs to the Section Medical Research)

2nd Edition—Featured Papers on the Origins of Life

edited by James R. Lyons

submission deadline 30 Jun 2026 | 7 articles | Viewed by 27170 | Submission Open

Keywords: astrobiology; astrochemistry; planetary science; prebiotic chemistry; chirality; chemical evolution; protocells; synthetic biology; complex systems

(This special issue belongs to the Section Origins of Life)

Recent Advances in Physiotherapy for Musculoskeletal Disorders

edited by

Miguel Ángel Rosety-Rodríguez

and

Jorge Góngora-Rodríguez

submission deadline 30 Jun 2026 | 6 articles | Viewed by 21844 | Submission Open

Keywords: musculoskeletal rehabilitation; emerging technologies; virtual reality; artificial intelligence; inflammatory genetics; physiotherapy; sports medicine; functional recovery

(This special issue belongs to the Section Physiology and Pathology)

The Emerging Role of Microbiota in Health and Diseases

edited by Edyta Juszczuk-Kubiak and Katarzyna Góralska

submission deadline 30 Jun 2026 | 7 articles | Viewed by 21499 | Submission Open

Keywords: microbiota; eubiosis; dysbiosis; microbiota– host interaction; microbiota– gut– brain axis; microbiome; bacteria– fungi interactions; microbiota modification; holobiont; cross-feeding; microbiota related diseases; microbiota functions

(This special issue belongs to the Section Microbiology)

Common and Novel Markers of Inflammation and Tissue Damage in Various Pathological Conditions—2nd Edition

edited by

Marzena Tylicka

Joanna Kamińska

and

Olga Koper-Lenkiewicz

submission deadline 30 Jun 2026 | 9 articles | Viewed by 15091 | Submission Open

Keywords: body fluids; cytokines; damage-associated molecular patterns (DAMPs); inflammatory response; injury; markers of inflammation and tissue damage; metalloproteinases; novel markers; pathological conditions; proteasome; tissue damage; tissue repair processes; various diseases

(This special issue belongs to the Section Physiology and Pathology)

Current Advances in Lung Cancer Diagnosis and Treatment

edited by

Hakyoung Kim

, Daesik Yang and

Zhiwei Hu

submission deadline 30 Jun 2026 | 4 articles | Viewed by 12838 | Submission Open

Keywords: lung cancer; underlying lung disease; radiotherapy; systemic therapy; survival outcomes; complication; biomarkers

(This special issue belongs to the Section Medical Research)

Move to Thrive: Pioneering Health and Resilience Through Physical Activity

edited by

Silvana Mirella Aliberti

Franca Di Meglio

and

Daria Nurzynska

submission deadline 30 Jun 2026 | 4 articles | Viewed by 6756 | Submission Open

Keywords: physical activity; inflammation modulation; chronic disease prevention; immune system adaptation; biomechanics; rehabilitation strategies; sports medicine; aging and physical activity; disability and movement; environmental and regional influences on exercise

(This special issue belongs to the Section Physiology and Pathology)

Advances in Livestock Breeding, Nutrition and Metabolism

edited by

Imran Khan

submission deadline 30 Jun 2026 | 3 articles | Viewed by 5601 | Submission Open

Keywords: genetic selection; livestock breeding; genome editing; animal nutrition; precision feeding; nutritional additives; feed conversion; metabolism; animal health; sustainability

(This special issue belongs to the Section Animal Science)

Update on Microalgae Metabolites

edited by

Eduardo Jacob-Lopes

and

Leila Queiroz Zepka

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5059 | Submission Open

Keywords: biosynthesis; culture conditions; bioactive compounds; biological activity; biorefinery; proteins; peptides; antifreeze proteins; enzymes; carbohydrates; exocellular polysaccharides; carbohydrate-binding proteins; lipids; fatty acids; chlorophylls; carotenoids; phycobiliproteins; vitamins; minerals; trace elements; sterols; secondary metabolites; downstream processing; purification; safety; regulatory issues; clinical tests

(This special issue belongs to the Section Microbiology)

Musculoskeletal Imaging: Innovations in Diagnostics and Interventional Therapies

edited by

Paolo Spinnato

submission deadline 30 Jun 2026 | 2 articles | Viewed by 5029 | Submission Open

Keywords: magnetic resonance imaging; bone and bones; computed tomography; sarcoma; interventional radiology

(This special issue belongs to the Section Medical Research)

Microalgae and Their Biotechnological Potential

edited by

Fantao Kong

, Yi Xin and Yuanxue Liang

submission deadline 30 Jun 2026 | 3 articles | Viewed by 4640 | Submission Open

Keywords: microalgae; biofuels; bioproducts; lipid metabolism; synthetic biology; system engineering

(This special issue belongs to the Section Microbiology)

Latest Updates on Clinical Microbiology and Antimicrobial Resistant Infection

edited by Jun Sung Hong

submission deadline 30 Jun 2026 | 4 articles | Viewed by 4546 | Submission Open

Keywords: enterobacteriaceae; antimicrobial resistance; infection; health

(This special issue belongs to the Section Microbiology)

Sialic Acid and Sialic Acid Derivatives in Biomedicine

edited by

Paola Rota

and

Marco Piccoli

submission deadline 30 Jun 2026 | 2 articles | Viewed by 4540 | Submission Open

Keywords: sialic acid; drug development; sialidase inhibitors; sialylation; sialidase; biomarker

(This special issue belongs to the Section Physiology and Pathology)

Role of Machine and Deep Learning in Drug Screening

edited by

Shahid Ali

and

Teng Zhou

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3729 | Submission Open

Keywords: machine learning in drug screening; deep learning in drug discovery; virtual screening; molecular docking and dynamics; personalized medicine

(This special issue belongs to the Section Pharmaceutical Science)

Helicobacter pylori: 2nd Edition

edited by

Ovidiu Pop

and

Simona Gurzu

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3517 | Submission Open

Keywords: H. pylori; cancers; antioxidative process; diagnostic methods

(This special issue belongs to the Section Microbiology)

Pathological and Clinical Updates on Eye Diseases

edited by Pier Luigi Surico and

Rohan Bir Singh

submission deadline 30 Jun 2026 | 1 articles | Viewed by 3356 | Submission Open

Keywords: ophthalmology; eye diseases; gene therapy; ocular surface; ocular immunology; cornea

(This special issue belongs to the Section Medical Research)

Research on Gastrointestinal Cancer and Nutritional Health

edited by

Irene Lidoriki

, Adam Mylonakis and Dimitrios Tsapralis

submission deadline 30 Jun 2026 | 2 articles | Viewed by 3195 | Submission Open

Keywords: dietary patterns; gastrointestinal cancer; clinical nutrition; nutritional status; nutritional assessment; metabolism; gastric cancer; esophageal cancer; pancreatic cancer; colorectal cancer

(This special issue belongs to the Section Medical Research)

Perspectives on Nutrition and Livestock Health

edited by

Liuting Wu

, Yan Wang and

Felix Kwame Amevor

submission deadline 30 Jun 2026 | 4 articles | Viewed by 2966 | Submission Open

Keywords: nutrition; animal health; animal reproductive; animal welfare; gut microbiome

(This special issue belongs to the Section Animal Science)

Advances in the Glyoxalase Pathway: Implications for Oxidative Stress Management in Cancer Therapy and in Age-Related Disease

edited by

Laura Cianfruglia

and

Salvatore Vaiasicca

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2539 | Submission Open

Keywords: glyoxalase system; methylglyoxal; advanced glycation end-products; dicarbonyl stress; oxidative stress; age-related disease; cancer

(This special issue belongs to the Section Physiology and Pathology)

Cranial Base Tumors: Pathogenesis, Diagnosis, and Treatments

edited by

Andrew J. Fishman

and Marcin Szymański

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2524 | Submission Open

Keywords: skull base tumors; neuro-oncology; endoscopic surgery; cranial nerve preservation; AI-assisted diagnostics; multidisciplinary management

(This special issue belongs to the Section Medical Research)

Channel Proteins and Transporters in Human Health and Disease

edited by

Giorgia Scarpellino

Giorgia Chinigò

and

Roberta De Zio

submission deadline 30 Jun 2026 | 2 articles | Viewed by 2356 | Submission Open

Keywords: channel proteins; transporters; ion channel

(This special issue belongs to the Section Genomics and Proteomics)

New Advances in the Treatment and Assessment of Temporomandibular Joint Disorders

edited by

Łukasz Rafał Pałka

submission deadline 30 Jun 2026 | 3 articles | Viewed by 2214 | Submission Open

Keywords: orofacial dysfunction; multifactorial etiology; advanced diagnostic technologies; biomechanical modeling of TMJ; novel imaging techniques; inflammatory and degenerative changes; interdisciplinary management; conservative therapy approaches; occlusal concepts; splint therapy design; physical therapy regimens; long-term implant treatment outcomes; personalized treatment strategies

(This special issue belongs to the Section Medical Research)

Neuroimaging and Integrative Analyses in Psychiatry and Addictive Disorders

edited by Arkadiusz Komorowski

submission deadline 30 Jun 2026 | 1 articles | Viewed by 2064 | Submission Open

Keywords: psychiatry; neuroimaging; forensic psychiatry; fMRI; PET; EEG; addiction; substance use disorders (SUD); psychotherapy; treatment-resistant depression (TRD); attention deficit hyperactivity disorder (ADHD)

(This special issue belongs to the Section Physiology and Pathology)

Post-Concussion Syndrome and Functional Neurological Disorder

edited by

Ioannis Asterios Mavroudis

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1936 | Submission Open

Keywords: post-concussion syndrome; functional neurological disorder; mild traumatic brain injury; cognitive dysfunction ; neuroimaging; biomarkers; neurorehabilitation

(This special issue belongs to the Section Medical Research)

Applications of Dermatoscopy in Skin Diseases: 2nd Edition

edited by

Paweł Pietkiewicz

Enzo Errichetti

and

Cristian Navarrete

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1899 | Submission Open

Keywords: melanoma; skin cancer; inflammoscopy; trichoscopy; ultraviolet reflectance dermatoscopy; skin of color; basal cell carcinoma; squamous cell carcinoma; nevus; digital dermoscopy

(This special issue belongs to the Section Medical Research)

Update on Obstructive Sleep Apnea (OSA)

edited by

Konstantinos Chaidas

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1678 | Submission Open

Keywords: obstructive sleep apnea; snoring; sleep-disordered breathing; adult sleep apnea; pediatric sleep apnea

(This special issue belongs to the Section Physiology and Pathology)

Vector-Borne Diseases and One Health

edited by

Jeronimo Alencar

, Shayenne Silva and

Michail Kotsyfakis

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1632 | Submission Open

Keywords: vector-borne diseases; One Health; malaria; dengue; Zika; chikungunya; yellow fever; West Nile virus; Lyme disease; leishmaniasis; Chagas

(This special issue belongs to the Section Animal Science)

Physical Rehabilitation for Musculoskeletal Disorders: 2nd Edition

edited by

You Gyoung Yi

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1548 | Submission Open

Keywords: physical rehabilitation; musculoskeletal disorders; pain management; range of motion; muscle strengthening; mobility enhancement; physical therapy; manual therapy; AI in rehabilitation

(This special issue belongs to the Section Medical Research)

Transplant Medicine: Updates and Current Challenges

edited by Phillipe Abreu

submission deadline 30 Jun 2026 | 2 articles | Viewed by 1472 | Submission Open

Keywords: robotic transplantation; organ transplants; transplant oncology

(This special issue belongs to the Section Medical Research)

Impact of Environmental Factors on the Diversity and Structure of Bacterial and Eukaryotic Communities

edited by

Jun Noda

and

Daisuke Tanaka

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1257 | Submission Open

Keywords: environmental factors; bacterial and eukaryotic communities; climate adaptation; pollution; microbial resilience; metagenomic analysis; amplicon sequencing; bioinformatics

(This special issue belongs to the Section Microbiology)

Cutting-Edge Research in Rhinology and Allergy: Unraveling Disease Mechanisms and Treatment Innovations

edited by Min-Seok Rha

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1245 | Submission Open

Keywords: rhinology; allergy; chronic rhinosinusitis; allergic rhinitis; asthma; precision medicine; clinical immunology; immunopathology; therapeutic innovation

Drug Safety and Outcomes in Respiratory and Critical Care Medicine

edited by

Josef Yayan

submission deadline 30 Jun 2026 | 1 articles | Viewed by 1208 | Submission Open

Keywords: drug safety; adverse drug reactions; pharmacovigilance; critical care medicine; respiratory diseases; clinical outcomes; intensive care pharmacotherapy; drug– drug interactions

(This special issue belongs to the Section Pharmaceutical Science)

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