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Most Recent

  • Review
  • Open Access

10 November 2025

Background: Randomized controlled trials (RCTs) are the foundation of evidence-based medicine. However, the rapid pace of technological innovation in cardiovascular surgery and interventional cardiology challenges the traditional RCT framework. Obser...

  • Systematic Review
  • Open Access
1,081 Views
15 Pages

Diagnostic Accuracy of Radiomics Versus Visual or Threshold-Based Assessment for Myocardial Scar/Fibrosis Detection on Cardiac MRI: A Systematic Review

  • Cian Peter Murray,
  • Hugo C. Temperley,
  • Robert S. Doyle,
  • Abdullahi Mohamed Khair,
  • Patrick Devitt,
  • Amal John and
  • Sajjad Matiullah

31 October 2025

Background: Myocardial scar and fibrosis predict adverse cardiac outcomes. Late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) is the reference standard for detection. However, it requires gadolinium-based contrast agents (GBCAs), whic...

  • Article
  • Open Access
1,130 Views
17 Pages

Comparison of Two Risk Calculators Based on Clinical Variables (MAGGIC and BCN Bio-HF) in Prediction of All-Cause Mortality After Acute Heart Failure Episode

  • Alejandro Gallego-Cuenca,
  • Esperanza Bueno-Juana,
  • Amelia Campos-Sáenz de Santamaría,
  • Vanesa Garcés-Horna,
  • Marta Sánchez-Marteles,
  • Juan I. Pérez-Calvo,
  • Ignacio Giménez-López and
  • Jorge Rubio-Gracia

30 October 2025

Background: Heart failure (HF) is common and deadly, affecting over 60 million people worldwide, and it remains a leading cause of hospitalization and post-discharge death. One-year mortality after an acute decompensated HF (ADHF) admission often app...

  • Article
  • Open Access
1,065 Views
21 Pages

Assessing the Characteristics of Modern Valvuloplasty Balloons Using a Robotic Non-Contact Optical Approach

  • Jiazhe Tang,
  • Xiaoyu Huang,
  • Timothy Williams,
  • David Hildick-Smith,
  • Rodrigo Aviles-Espinosa and
  • Elizabeth Rendon-Morales

28 October 2025

Background: Balloon aortic valvuloplasty is a procedure for treating aortic stenosis, as well as being a preliminary step before transcatheter aortic valve implantation. Balloon aortic valvuloplasty requires inserting a balloon catheter into the aort...

  • Article
  • Open Access
2,445 Views
13 Pages

Myocardial Work’s Impact in the Evaluation of Advanced Heart Failure

  • Luca Martini,
  • Antonio Pagliaro,
  • Hatem Soliman Aboumarie,
  • Massimo Maccherini,
  • Serafina Valente,
  • Giulia Elena Mandoli,
  • Michael Y. Henein and
  • Matteo Cameli

3 September 2025

Background: Left ventricular myocardial work (MW) derived from non-invasive pressure–strain loops has emerged as a load-adjusted index of contractile performance. Its value for risk stratification in advanced heart failure (HF) remains uncertai...

  • Article
  • Open Access
1,165 Views
8 Pages

Anxiety and Depression Symptoms in Children and Adolescents with Congenital Heart Disease

  • Isabel Uphoff,
  • Charlotte Schöneburg,
  • Renate Oberhoffer-Fritz,
  • Peter Ewert and
  • Jan Müller

15 August 2025

Background: Congenital heart disease (CHD) is associated with an increased risk of anxiety and depression in adults. However, little is known about the mental health of children and adolescents with CHD. The aim of this study was to assess difference...

  • Systematic Review
  • Open Access
2,050 Views
16 Pages

Systematic Review and Meta-Analysis of Cardiac MRI T1 and ECV Measurements in Pre-Heart Failure Populations

  • Robert S. Doyle,
  • Ross Walsh,
  • Jamie Walsh,
  • Hugo C. Temperley,
  • John McCormick and
  • Gerard Giblin

13 August 2025

Background/Objectives: Heart failure (HF) often develops from a prolonged asymptomatic phase where early detection could prevent progression. Pre-heart failure (pre-HF) populations—those with risk factors (Stage A) or subclinical myocardial cha...

  • Systematic Review
  • Open Access
2,825 Views
16 Pages

Machine Learning Application in Different Imaging Modalities for Detection of Obstructive Coronary Artery Disease and Outcome Prediction: A Systematic Review and Meta-Analysis

  • Peter McGranaghan,
  • Doreen Schoeppenthau,
  • Antonia Popp,
  • Anshul Saxena,
  • Sharat Kothakapu,
  • Muni Rubens,
  • Gabriel Jiménez,
  • Pablo Gordillo,
  • Emir Veledar and
  • Alaa Abd El Al
  • + 3 authors

7 August 2025

Background/Objectives: Invasive coronary angiography (ICA) is the gold standard for the diagnosis of coronary artery disease (CAD), with various non-invasive imaging modalities also available. Machine learning (ML) methods are increasingly applied to...

  • Article
  • Open Access
846 Views
10 Pages

6 August 2025

Background/Objectives: While elevated Lp(a) levels are associated with incident heart failure development, the role of Lp(a) in established heart failure with reduced ejection fraction (HFrEF) versus heart failure with preserved ejection fraction (HF...

  • Article
  • Open Access
3,766 Views
14 Pages

Evaluating Large Language Models in Cardiology: A Comparative Study of ChatGPT, Claude, and Gemini

  • Michele Danilo Pierri,
  • Michele Galeazzi,
  • Simone D’Alessio,
  • Melissa Dottori,
  • Irene Capodaglio,
  • Christian Corinaldesi,
  • Marco Marini and
  • Marco Di Eusanio

19 July 2025

Background: Large Language Models (LLMs) such as ChatGPT, Claude, and Gemini are being increasingly adopted in medicine; however, their reliability in cardiology remains underexplored. Purpose of the study: To compare the performance of three general...

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Hearts - ISSN 2673-3846