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Biosensors, Volume 9, Issue 3

September 2019 - 30 articles

Cover Story: This research aims to minimize the power consumption of the organic optoelectronic pulse meter biosensor for long-term monitoring of the PPG waveforms wirelessly. A reflectance-type optoelectronic pulse meter composed of a red organic light-emitting diode (OLED) and an organic photodiode (OPD) fabricated monolithically on a glass substrate was proposed to measure the PPG signals. Two design structures with different OLED areas and gaps between an OLED and an OPD were examined for minimizing the power consumption and noise level of the biosensor pulse meter and evaluated using the PPG signal, which was successfully collected from a fingertip. The proposed reflectance-based organic pulse meter was operated successfully with an ultra-low power consumption down to 8 μW at 18 dB SNR, and with a clear PPG signal up to 46 dB SNR at a constant current of 93.6 μA. View this paper.
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Articles (30)

  • Article
  • Open Access
18 Citations
7,312 Views
14 Pages

Design and Evaluation of a Non-Contact Bed-Mounted Sensing Device for Automated In-Home Detection of Obstructive Sleep Apnea: A Pilot Study

  • Clara Mosquera-Lopez,
  • Joseph Leitschuh,
  • John Condon,
  • Chad C. Hagen,
  • Uma Rajhbeharrysingh,
  • Cody Hanks and
  • Peter G. Jacobs

22 July 2019

We conducted a pilot study to evaluate the accuracy of a custom built non-contact pressure-sensitive device in diagnosing obstructive sleep apnea (OSA) severity as an alternative to in-laboratory polysomnography (PSG) and a Type 3 in-home sleep apnea...

  • Article
  • Open Access
12 Citations
7,271 Views
14 Pages

Diazonium-Modified Screen-Printed Electrodes for Immunosensing Growth Hormone in Blood Samples

  • Nan Li,
  • Ari M. Chow,
  • Hashwin V. S. Ganesh,
  • Melanie Ratnam,
  • Ian R. Brown and
  • Kagan Kerman

17 July 2019

Altered growth hormone (GH) levels represent a major global health challenge that would benefit from advances in screening methods that are rapid and low cost. Here, we present a miniaturized immunosensor using disposable screen-printed carbon electr...

  • Review
  • Open Access
165 Citations
22,626 Views
16 Pages

Towards Lateral Flow Quantitative Assays: Detection Approaches

  • Alexandr E. Urusov,
  • Anatoly V. Zherdev and
  • Boris B. Dzantiev

17 July 2019

Point-of-care (POC) or bedside analysis is a global trend in modern diagnostics. Progress in POC testing has largely been provided by advanced manufacturing technology for lateral flow (immunochromatographic) test strips. They are widely used to rapi...

  • Article
  • Open Access
36 Citations
16,086 Views
13 Pages

Reflectance-Based Organic Pulse Meter Sensor for Wireless Monitoring of Photoplethysmogram Signal

  • Fahed Elsamnah,
  • Anubha Bilgaiyan,
  • Muhamad Affiq,
  • Chang-Hoon Shim,
  • Hiroshi Ishidai and
  • Reiji Hattori

10 July 2019

This paper compares the structural design of two organic biosensors that minimize power consumption in wireless photoplethysmogram (PPG) waveform monitoring. Both devices were fabricated on the same substrate with a red organic light-emitting diode (...

  • Review
  • Open Access
246 Citations
17,825 Views
19 Pages

The Role of Electrochemical Immunosensors in Clinical Analysis

  • Fariba Mollarasouli,
  • Sevinc Kurbanoglu and
  • Sibel A. Ozkan

An immunosensor is a kind of affinity biosensor based on interactions between an antigen and specific antigen immobilized on a transducer surface. Immunosensors possess high selectivity and sensitivity due to the specific binding between antibody and...

  • Article
  • Open Access
40 Citations
9,340 Views
14 Pages

Cyclic Olefin Copolymer Microfluidic Devices for Forensic Applications

  • Brigitte Bruijns,
  • Andrea Veciana,
  • Roald Tiggelaar and
  • Han Gardeniers

Microfluidic devices offer important benefits for forensic applications, in particular for fast tests at a crime scene. A large portion of forensic applications require microfluidic chip material to show compatibility with biochemical reactions (such...

  • Article
  • Open Access
73 Citations
9,381 Views
12 Pages

Development of a Label-Free Electrochemical Aptasensor for the Detection of Tau381 and its Preliminary Application in AD and Non-AD Patients’ Sera

  • Dan Tao,
  • Bingqing Shui,
  • Yingying Gu,
  • Jing Cheng,
  • Weiying Zhang,
  • Nicole Jaffrezic-Renault,
  • Shizhen Song and
  • Zhenzhong Guo

30 June 2019

The electrochemical aptamer sensor has been designed for detecting tau381, a critical biomarker of Alzheimer′s disease in human serum. The aptasensor is obtained by immobilizing the aptamer on a carboxyl graphene/thionin/gold nanoparticle modif...

  • Article
  • Open Access
11 Citations
7,367 Views
15 Pages

Plasmonic Detection of Glucose in Serum Based on Biocatalytic Shape-Altering of Gold Nanostars

  • Masauso Moses Phiri,
  • Danielle Wingrove Mulder and
  • Barend Christiaan Vorster

29 June 2019

Nanoparticles have been used as signal transducers for optical readouts in biosensors. Optical approaches are cost-effective with easy readout formats for clinical diagnosis. We present a glucose biosensor based on the biocatalytic shape-altering of...

  • Article
  • Open Access
25 Citations
7,554 Views
11 Pages

EMG-Based Characterization of Walking Asymmetry in Children with Mild Hemiplegic Cerebral Palsy

  • Francesco Di Nardo,
  • Annachiara Strazza,
  • Alessandro Mengarelli,
  • Stefano Cardarelli,
  • Andrea Tigrini,
  • Federica Verdini,
  • Alberto Nascimbeni,
  • Valentina Agostini,
  • Marco Knaflitz and
  • Sandro Fioretti

27 June 2019

Hemiplegia is a neurological disorder that is often detected in children with cerebral palsy. Although many studies have investigated muscular activity in hemiplegic legs, few EMG-based findings focused on unaffected limb. This study aimed to quantif...

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Biosensors - ISSN 2079-6374