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Review

The Role of Electrochemical Immunosensors in Clinical Analysis

1
Department of Analytical Chemistry, Faculty of Pharmacy, Ankara University, 06560 Ankara, Turkey
2
Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz 51666-16471, Iran
*
Author to whom correspondence should be addressed.
Biosensors 2019, 9(3), 86; https://doi.org/10.3390/bios9030086
Received: 9 May 2019 / Revised: 4 July 2019 / Accepted: 5 July 2019 / Published: 9 July 2019
(This article belongs to the Special Issue Electrochemical Immunosensor)
An immunosensor is a kind of affinity biosensor based on interactions between an antigen and specific antigen immobilized on a transducer surface. Immunosensors possess high selectivity and sensitivity due to the specific binding between antibody and corresponding antigen, making them a suitable platform for several applications especially in the medical and bioanalysis fields. Electrochemical immunosensors rely on the measurements of an electrical signal recorded by an electrochemical transducer and can be classed as amperometric, potentiometric, conductometric, or impedimetric depending on the signal type. Among the immunosensors, electrochemical immunosensors have been more perfected due to their simplicity and, especially their ability to be portable, and for in situ or automated detection. This review addresses the potential of immunosensors destined for application in clinical analysis, especially cancer biomarker diagnosis. The emphasis is on the approaches used to fabricate electrochemical immunosensors. A general overview of recent applications of the developed electrochemical immunosensors in the clinical approach is described. View Full-Text
Keywords: clinical analysis; electrochemistry; immunosensors; biomarker; label free; labeled clinical analysis; electrochemistry; immunosensors; biomarker; label free; labeled
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MDPI and ACS Style

Mollarasouli, F.; Kurbanoglu, S.; Ozkan, S.A. The Role of Electrochemical Immunosensors in Clinical Analysis. Biosensors 2019, 9, 86. https://doi.org/10.3390/bios9030086

AMA Style

Mollarasouli F, Kurbanoglu S, Ozkan SA. The Role of Electrochemical Immunosensors in Clinical Analysis. Biosensors. 2019; 9(3):86. https://doi.org/10.3390/bios9030086

Chicago/Turabian Style

Mollarasouli, Fariba; Kurbanoglu, Sevinc; Ozkan, Sibel A. 2019. "The Role of Electrochemical Immunosensors in Clinical Analysis" Biosensors 9, no. 3: 86. https://doi.org/10.3390/bios9030086

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