Table of Contents
Vaccines, Volume 8, Issue 1 (March 2020) – 144 articles
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Cover Story (view full-size image) Multiplex PCR-based neutralization (MPBN) assay for anti-poliovirus antibodies’ titration uses a [...] Read more. Multiplex PCR-based neutralization (MPBN) assay for anti-poliovirus antibodies’ titration uses a quantitative multiplex one-step RT-PCR as a read out instead of the cytopathic effect used in conventional neutralization assay. The MPBN is the first neutralization assay that specifically titrates anti-poliovirus antibodies against the three serotypes of the virus in the same reaction, and it can be completed in two to three days instead of the ten days needed for the conventional assay, as well as automated for high-throughput implementation. View this paper