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Viruses, Volume 16, Issue 2

February 2024 - 150 articles

Cover Story: Seasonal infection rates of individual viruses are influenced by synergistic or inhibitory interactions between coincident viruses. We explored the immunopathologic basis of SARS-CoV-2 and influenza A (H1N1pdm09) interactions in Syrian hamsters. Influenza given 48 h prior to SARS-CoV-2 protected hamsters against SARS-CoV-2 disease. This was accompanied by a decreased SARS-CoV-2 viral load and lower cytokine levels in the lungs of the protected animals. Influenza infection induced rapid upregulation of innate immune and antiviral pathways in the upper respiratory tract shortly after infection, thus providing a less favorable environment for subsequent SARS-CoV-2 infection. On a population level, interaction between these two viruses may influence their relative seasonal infection rates. View this paper
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Articles (150)

  • Review
  • Open Access
34 Citations
22,273 Views
53 Pages

19 February 2024

Influenza A virus (IAV) is the primary causative agent of influenza, colloquially called the flu. Each year, it infects up to a billion people, resulting in hundreds of thousands of human deaths, and causes devastating avian outbreaks with worldwide...

  • Article
  • Open Access
4 Citations
3,666 Views
13 Pages

Emergence of Crimean–Congo Hemorrhagic Fever Virus in Eastern Senegal in 2022

  • Ousseynou Sene,
  • Samba Niang Sagne,
  • Déthié Ngom,
  • Moussa Moise Diagne,
  • Aminata Badji,
  • Aliou Khoulé,
  • El Hadji Ndiaye,
  • Safietou Sankhe,
  • Cheikh Loucoubar and
  • Mawlouth Diallo
  • + 13 authors

19 February 2024

Crimean–Congo hemorrhagic fever (CCHF), the most widespread tick-borne viral human infection, poses a threat to global health. In this study, clinical samples collected through national surveillance systems were screened for acute CCHF virus (C...

  • Article
  • Open Access
3 Citations
3,802 Views
10 Pages

19 February 2024

Objectives: In Thailand, there has been a strategy to prevent the mother-to-child transmission of HBV for over 30 years. However, there is still a lack of empirical evidence regarding the effectiveness of this strategy. This study aims to investigate...

  • Article
  • Open Access
1 Citations
2,637 Views
14 Pages

Metabolic Alterations in Mothers Living with HIV and Their HIV-Exposed, Uninfected Infants

  • Louise D. V. du Toit,
  • Shayne Mason,
  • Mari van Reenen,
  • Theresa M. Rossouw and
  • Roan Louw

19 February 2024

HIV-exposed, uninfected (HEU) children present with suboptimal growth and a greater susceptibility to infection in early life when compared to HIV-unexposed, uninfected (HUU) children. The reasons for these findings are poorly understood. We used a m...

  • Article
  • Open Access
5 Citations
3,866 Views
12 Pages

Application of CRISPR/Cas9 for Rapid Genome Editing of Pseudorabies Virus and Bovine Herpesvirus-1

  • Wanqi Yu,
  • Jingyi Liu,
  • Yingnan Liu,
  • Maria Forlenza and
  • Hongjun Chen

18 February 2024

The CRISPR/Cas9 system is widely used to manipulate viral genomes. Although Alphaherpesvirinae genomes are large and complicated to edit, in recent years several Pseudorabies virus (PRV) mutants have been successfully generated using the CRISPR/Cas9...

  • Article
  • Open Access
5 Citations
2,829 Views
14 Pages

Generation of High-Quality African Swine Fever Virus Complete Genome from Field Samples by Next-Generation Sequencing

  • Chuan Shi,
  • Qinghua Wang,
  • Yutian Liu,
  • Shujuan Wang,
  • Yongqiang Zhang,
  • Chunju Liu,
  • Yongxin Hu,
  • Dongxia Zheng,
  • Chengyou Sun and
  • Fangfang Song
  • + 4 authors

18 February 2024

African swine fever (ASF) is a lethal contagious viral disease of domestic pigs and wild boars caused by the African swine fever virus (ASFV). The pandemic spread of ASF has caused severe effects on the global pig industry. Whole-genome sequencing pr...

  • Article
  • Open Access
2 Citations
2,831 Views
21 Pages

18 February 2024

Serpentoviruses are a subfamily of positive sense RNA viruses in the order Nidovirales, family Tobaniviridae, associated with respiratory disease in multiple clades of reptiles. While the broadest viral diversity is reported from captive pythons, oth...

  • Article
  • Open Access
3 Citations
2,252 Views
12 Pages

Phylogenetic and Molecular Analysis of the Porcine Epidemic Diarrhea Virus in Mexico during the First Reported Outbreaks (2013–2017)

  • José Francisco Rivera-Benítez,
  • Rebeca Martínez-Bautista,
  • Raúl González-Martínez,
  • Jazmín De la Luz-Armendáriz,
  • Irma Herrera-Camacho,
  • Nora Rosas-Murrieta,
  • Laura Márquez-Valdelamar and
  • Rocio Lara

18 February 2024

The characteristics of the whole PEDV genome that has circulated in Mexico from the first outbreak to the present are unknown. We chose samples obtained from 2013 to 2017 and sequenced them, which enabled us to identify the genetic variation and phyl...

  • Review
  • Open Access
11 Citations
3,176 Views
14 Pages

18 February 2024

Cytokines are signaling molecules that play a role in myriad processes, including those occurring during diseases and homeostasis. Their homeostatic function begins during embryogenesis and persists throughout life, including appropriate signaling fo...

  • Brief Report
  • Open Access
1 Citations
1,862 Views
9 Pages

17 February 2024

Boosepivirus is a new genus in the Picornaviridae family. Boosepiviruses (BooVs) are genetically classified into three species: A, B, and C. Initially, Boosepivirus A and B were identified in cattle, whereas Boosepivirus C was detected in sheep. Rece...

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Viruses - ISSN 1999-4915