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Medicina, Volume 57, Issue 7

July 2021 - 93 articles

Cover Story:

Sphingolipids are both structural molecules that are essential for cell architecture, and second messengers that are involved in cell and organism homeostasis. Moreover, sphingolipid metabolism disfunction is implicated in several diseases, such as cancer.
Studies on sphingolipids and metabolic enzymes are of vital importance for developing novel therapeutic strategies and for improving conventional therapies in carcinogenesis and cancer dissemination. View this paper

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Articles (93)

  • Review
  • Open Access
22 Citations
10,557 Views
7 Pages

Limosilactobacillus reuteri Strains as Adjuvants in the Management of Helicobacter pylori Infection

  • Costantino Dargenio,
  • Vanessa Nadia Dargenio,
  • Francesca Bizzoco,
  • Flavia Indrio,
  • Ruggiero Francavilla and
  • Fernanda Cristofori

20 July 2021

Helicobacter pylori (HP) is a Gram-negative bacterium which finds its suitable habitat in the stomach. The infection affects about half of the global population with high variability in prevalence among regions and for age. HP is the main causative a...

  • Case Report
  • Open Access
4 Citations
3,318 Views
4 Pages

A Case of Incidental Schwannoma Mimicking Necrotic Metastatic Lymph Node from Bladder Cancer

  • Jeong-Hyouk Choi,
  • Koo-Han Yoo,
  • Dong-Gi Lee,
  • Gyeong-Eun Min,
  • Gou-Young Kim and
  • Tae-Soo Choi

19 July 2021

Background and Objectives: Retroperitoneal schwannoma is a very rare case of schwannoma which commonly occurs in the other part of the body. However, it is difficult to distinguish schwannoma from other tumors before pathological examination because...

  • Article
  • Open Access
7 Citations
3,027 Views
10 Pages

19 July 2021

Background and Objectives: Angiogenesis describes the outgrowth of new capillaries from already existing ones. Different biomarkers regulate this process. Physical exercise and hypoxia are key stimuli for the activation of different angiogenic molecu...

  • Review
  • Open Access
28 Citations
9,372 Views
24 Pages

Ceramide Metabolism Enzymes—Therapeutic Targets against Cancer

  • Ana Gomez-Larrauri,
  • Upasana Das Adhikari,
  • Marta Aramburu-Nuñez,
  • Antía Custodia and
  • Alberto Ouro

19 July 2021

Sphingolipids are both structural molecules that are essential for cell architecture and second messengers that are involved in numerous cell functions. Ceramide is the central hub of sphingolipid metabolism. In addition to being the precursor of com...

  • Review
  • Open Access
27 Citations
10,022 Views
7 Pages

19 July 2021

Keloids are a benign fibroproliferative disease with a high tendency of recurrence. Keloids cause functional impairment, disfigurement, pruritus, and low quality of life. Many therapeutic options have been used for keloids. However, the high recurren...

  • Case Report
  • Open Access
9 Citations
4,401 Views
10 Pages

Microsurgical Clipping of Carotid-Ophthalmic Tandem Aneurysms: Case Report and Surgical Nuances

  • Matias Costa,
  • Matías Baldoncini,
  • Zachary L. Tataryn,
  • Mickaela Echavarria Demichelis,
  • Agustin Conde,
  • Cynthia Purves,
  • Alice Giotta Lucifero,
  • Juha Hernesniemi and
  • Sabino Luzzi

19 July 2021

Tandem intracranial aneurysms (TandIAs) are rare but inherently complex, and special technical considerations are required for their surgical management. The present case highlights the key surgical aspects of two carotid-ophthalmic TandIAs incidenta...

  • Article
  • Open Access
28 Citations
5,356 Views
10 Pages

Safety and Tolerability of the BNT162b2 mRNA COVID-19 Vaccine in Dialyzed Patients. COViNEPH Project

  • Karolina Polewska,
  • Piotr Tylicki,
  • Bogdan Biedunkiewicz,
  • Angelika Rucińska,
  • Aleksandra Szydłowska,
  • Alicja Kubanek,
  • Iwona Rosenberg,
  • Sylwia Rodak,
  • Waldemar Ślizień and
  • Marcin Renke
  • + 2 authors

19 July 2021

Background and Objectives: The Pfizer-BioNTech (BNT162b2) COVID-19 mRNA vaccine has demonstrated excellent efficacy and safety in phase 3 trials. However, no dialyzed patients were included, and therefore safety data for this patient group is lacking...

  • Review
  • Open Access
25 Citations
7,486 Views
13 Pages

18 July 2021

Medical management of a chronic obstructive pulmonary disease (COPD) patient must incorporate a broadened and holistic approach to achieve optimal outcomes. This is best achieved with integrated care, which is based on the chronic care model of disea...

  • Article
  • Open Access
9 Citations
2,750 Views
9 Pages

Molecular Analysis of Prothrombotic Gene Variants in Patients with Acute Ischemic Stroke and with Transient Ischemic Attack

  • Gustavo Cernera,
  • Marika Comegna,
  • Monica Gelzo,
  • Marcella Savoia,
  • Dario Bruzzese,
  • Mauro Mormile,
  • Federica Zarrilli,
  • Felice Amato,
  • Pierpaolo Di Micco and
  • Giuseppe Castaldo

17 July 2021

Background and objectives: ischemic stroke (IS) is among the most frequent causes of death worldwide; thus, it is of paramount relevance to know predisposing factors that may help to identify and treat the high-risk subjects. Materials and Methods:we...

  • Case Report
  • Open Access
2 Citations
2,628 Views
5 Pages

COVID-19 during Early Phase of Autologous Stem Cell Transplantation

  • Sławomir Milczarek,
  • Bartłomiej Baumert,
  • Anna Sobuś,
  • Ewa Wilk-Milczarek,
  • Krzysztof Sommerfeld,
  • Bogumiła Osękowska,
  • Ewa Borowiecka,
  • Edyta Paczkowska,
  • Aleksandra Łanocha and
  • Wojciech Poncyliusz
  • + 2 authors

17 July 2021

We present one of few cases of COVID-19 occurrence during the early phase of autologous hematopoietic stem cell transplantation. We observed an interesting correlation between the patient’s rapid clinical deterioration and myeloid reconstitution that...

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Medicina - ISSN 1648-9144