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Medicina publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Recent Advances and Future Challenges in Colorectal Surgery

edited by Athanasios Syllaios and Nikoletta Dimitriou

submission deadline 15 Aug 2025 | 4 articles | Viewed by 6622 | Submission Open

Keywords: colorectal cancer; IBD; robotic; laparoscopic; minimally invasive approaches; TAMIS; transanal; artificial intelligence; colorectal benign diseases; fluorescent methods

(This special issue belongs to the Section Gastroenterology & Hepatology)

Advances in Cancer Cell Metastasis and Its Inhibition

edited by

Amit K. Tripathi

and

Yogesh Srivastava

submission deadline 15 Aug 2025 | Viewed by 243 | Submission Open

Keywords: cancer metastasis; tumor inhibition; cellular mechanisms; therapeutic strategies; molecular biology; signal transduction; tumor microenvironment; chemotherapy resistance; targeted therapy; biomarkers

(This special issue belongs to the Section Oncology)

Management and Diagnosis of Infertility and Recurrent Abortions in Obstetrics and Gynecology

edited by Peter Drakakis,

Anastasios Potiris

and Sofoklis Stavros

submission deadline 20 Aug 2025 | 5 articles | Viewed by 12315 | Submission Open

Keywords: male and female infertility; recurrent pregnancy loss (RPL); recurrent implantation failure (RIF); assisted reproductive technologies (ART); early pregnancy

(This special issue belongs to the Section Obstetrics and Gynecology)

Diagnosis and Treatment of Acute Pancreatitis

edited by

Manuela Mastronardi

, Alan Biloslavo and Antonio La Greca

submission deadline 20 Aug 2025 | 3 articles | Viewed by 4418 | Submission Open

Keywords: acute pancreatitis; endoscopy; minimally invasive surgery; microbiota; artificial intelligence

(This special issue belongs to the Section Gastroenterology & Hepatology)

Epidemiology of Autiommune and Metabolic Diseases

edited by Daniela Fodor and Bogdan Augustin Chis

submission deadline 20 Aug 2025 | 1 articles | Viewed by 1073 | Submission Open

Keywords: autoimmune system; metabolic syndrome; epidemiology

(This special issue belongs to the Section Endocrinology)

Challenges in Prenatal Diagnosis and Maternal–Fetal Medicine in Adolescent Pregnancies

edited by

Agnieszka Drosdzol-Cop

and

Jakub Staniczek

submission deadline 20 Aug 2025 | Viewed by 162 | Submission Open

Keywords: adolescent pregnancy; high-risk obstetrics; prenatal care advancements; fetal anomalies; pre-eclampsia and preterm birth; nutritional interventions; psychosocial support in pregnancy; maternal health disparities; advanced ultrasound diagnostics; adolescent maternal outcomes

(This special issue belongs to the Section Obstetrics and Gynecology)

Advances in Anorectal and Colorectal Surgery

edited by

Claudio Gambardella

submission deadline 25 Aug 2025 | Viewed by 206 | Submission Open

Keywords: colorectal surgery; anorectal disorders; laparoscopic surgery; robotic surgery; oncologic surgery; minimally invasive techniques; functional anorectal disorders; surgical innovations; NOSES (natural orifice specimen extraction surgery); colorectal cancer management

(This special issue belongs to the Section Gastroenterology & Hepatology)

Updates on Risk Factors and Prevention of Coronary Artery Disease

edited by

Antoniu Petris

and

Valentin Chioncel

submission deadline 30 Aug 2025 | 1 articles | Viewed by 785 | Submission Open

Keywords: coronary artery disease; risk prediction; diabetes mellitus; hypertension; dyslipidemia; prevention; coronary angioplasty

(This special issue belongs to the Section Cardiology)

Outcomes After Surgical Treatment of Pelvic Organ Prolapse

edited by Justina Kačerauskienė and Roger Roman Dmochowski

submission deadline 30 Aug 2025 | 1 articles | Viewed by 630 | Submission Open

Keywords: pelvic organ prolapse; surgery; recurrence; vaginal hysterectomy; sacrocolpopexy; Manchester operation; sacrospinous fixation; native tissue

(This special issue belongs to the Section Obstetrics and Gynecology)

Early Diagnosis and Treatment of Cardiovascular Disease

edited by Elena Bobescu and Mihaela-Viviana Ivan

submission deadline 31 Aug 2025 | 8 articles | Viewed by 15518 | Submission Open

Keywords: coronary artery disease; heart failure; comorbidities; chronic kidney disease; anemia; diabetes mellitus; arrhythmias; hypertension; dyslipidemia; novel biomarkers

(This special issue belongs to the Section Cardiology)

Physiotherapy in Musculoskeletal Pain: Assessment and Management

edited by Mónica Grande-Alonso and

Ferran Cuenca-Martínez

submission deadline 31 Aug 2025 | 5 articles | Viewed by 9137 | Submission Open

Keywords: musculoskeletal pain; sensorimotor factors; therapeutic exercise; motor imagery; new technologies; chronic pain; therapeutic education; manual therapy; rehabilitation; functional evaluation

(This special issue belongs to the Section Sports Medicine and Sports Traumatology)

Research on Oral and Maxillofacial Surgery

edited by Luca Aquilanti and

Giorgio Rappelli

submission deadline 31 Aug 2025 | 6 articles | Viewed by 6652 | Submission Open

Keywords: guided bone regeneration; CAD– CAM technology; digital dentistry; digital maxillofacial surgery; biomaterials; maxillofacial reconstructive surgery; novel medical devices

(This special issue belongs to the Section Dentistry and Oral Health)

Intracranial Aneurysms, Subarachnoid Hemorrhage and Delayed Cerebral Ischemia

edited by Leszek Michał Sagan and

Tomasz Klepinowski

submission deadline 31 Aug 2025 | 3 articles | Viewed by 4647 | Submission Open

Keywords: intracranial aneurysm; subarachnoid hemorrhage; vasospasm; delayed cerebral ischemia; stroke; embolization; coiling; clipping

(This special issue belongs to the Section Neurology)

Efficacy of Transcranial Electrical Current and Magnetic Stimulation Treatment Options for Alzheimer’s Disease

edited by

Zahra Moussavi

submission deadline 31 Aug 2025 | 2 articles | Viewed by 4532 | Submission Open

Keywords: transcranial electrical current estimation; transcranial magnetic stimulation; Alzheimer’ s disease; deep current stimulation

(This special issue belongs to the Section Neurology)

New Advances in Urology and Nephrology Disease: From Diagnosis to Treatment—2nd Edition

edited by Razvan-Ionut Popescu and

Rǎzvan Cosmin Petca

submission deadline 31 Aug 2025 | 5 articles | Viewed by 4441 | Submission Open

Keywords: prostate cancer; bladder cancer; renal cancer; kidney stones; urinary tract infections; chronic kidney disease; dialysis

(This special issue belongs to the Section Urology & Nephrology)

Advancing Our Understanding and Management of Low Back Pain: A Global Perspective

edited by

Juan Antonio Valera-Calero

submission deadline 31 Aug 2025 | 2 articles | Viewed by 3860 | Submission Open

Keywords: low back pain; pain management; global health; musculoskeletal diseases; rehabilitation

(This special issue belongs to the Section Neurology)

Latest Advances in Asthma and COPD

edited by Stefania Principe and

Nicola Scichilone

submission deadline 31 Aug 2025 | 3 articles | Viewed by 3776 | Submission Open

Keywords: asthma; COPD; disease mechanisms; precision medicine; epidemiology; technologies

(This special issue belongs to the Section Pulmonology)

Spinal Neurosurgery: Current Treatment and Future Options

edited by

Giuseppe Di Perna

Antonio Colamaria

and

Fabio Cofano

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1371 | Submission Open

Keywords: spinal neurosurgery; robotic surgery; minimally invasive spine surgery; spine tumors; endoscopic surgery; spine technology

(This special issue belongs to the Section Neurology)

New Research on Endodontic Therapy

edited by

António Ginjeira

and

Abayomi Omokeji Baruwa

submission deadline 31 Aug 2025 | 1 articles | Viewed by 1155 | Submission Open

Keywords: endodontics; root canal therapy; root anatomy; pulp therapy; endodontic microsurgery; education; rotary endodontics

(This special issue belongs to the Section Dentistry and Oral Health)

Diagnostic Value of Biomedical Imaging in Obstetrics and Gynecology

edited by

Yi Cheng Wu

and Changching Yeh

submission deadline 31 Aug 2025 | 1 articles | Viewed by 969 | Submission Open

Keywords: ultrasound; Doppler ultrasound; 3D/4D ultrasound; fetal imaging; fetal MRI; prenatal medicine; gynecologic disease; laparoscopy

(This special issue belongs to the Section Obstetrics and Gynecology)

Trauma, Critical Care, and Acute Care Surgery

edited by

Luciana Teodora Rotaru

and Stelian Mogoanta

submission deadline 31 Aug 2025 | 1 articles | Viewed by 818 | Submission Open

Keywords: golden hour; air medical evacuation; damage control; trauma centers; coagulopathy; pain management; dispatch centers; triage; incident command system; telemedicine

(This special issue belongs to the Section Surgery)

Recent Advances in Cervical and Vulvar Cancer

edited by Silviu Cristian Voinea and

Sinziana Ionescu

submission deadline 31 Aug 2025 | Viewed by 425 | Submission Open

Keywords: gynaeco-oncology; women’ s health; surgery; radiotherapy; chemotherapy; lymphadenectomy; sentinel lymph node; radical hysterectomy; vulvectomy; brachytherapy

(This special issue belongs to the Section Obstetrics and Gynecology)

Skin Cancer: Advances in Early Diagnosis and Treatment

edited by

Jose Juan Pereyra Rodriguez

Azahara Rodríguez-Luna

and Juan Carlos Hernández-Rodríguez

submission deadline 31 Aug 2025 | Viewed by 226 | Submission Open

Keywords: skin cancer; early diagnosis; dermoscopy; total body photography; confocal microscopy; melanoma; basal cell carcinoma; cutaneous squamous cell carcinoma; Merkel cell carcinoma; cutaneous lymphoma; cutaneous sarcoma

(This special issue belongs to the Section Dermatology)

Underserved Ophthalmology Healthcare

edited by

Jay Chhablani

and Anindya Samanta

submission deadline 31 Aug 2025 | Viewed by 209 | Submission Open

Keywords: underserved ophthalmology; unsheltered ophthalmology; homeless ophthalmology; telemedicine; mobile ophthalmology clinic; free ophthalmology clinic

(This special issue belongs to the Section Ophthalmology)

The Aesthetic Face of Orthognathic Surgery

edited by

Vincenzo Abbate

and

Giovanni Audino

submission deadline 1 Sep 2025 | 2 articles | Viewed by 1590 | Submission Open

Keywords: orthognathic surgery; rhinoplasty; aesthetic facial surgery; orthofacial surgery; fat grafting; 3D VSP; cephalometries

(This special issue belongs to the Section Surgery)

Sports Injuries: Prevention, Treatment and Rehabilitation

edited by Luis Suárez-Arrones,

Francisco Javier Núñez Sánchez

Ramona Ritzmann

and Cristophe Lambert

submission deadline 15 Sep 2025 | 4 articles | Viewed by 5387 | Submission Open

Keywords: exercise; return to sport; rehabilitation; sports therapy; muscle; tendon; joint; surgery; MRI

(This special issue belongs to the Section Orthopedics)

Chronic Rhinosinusitis with Nasal Polyps: Latest Trends in Diagnosis and Treatment

edited by

Bruno Galletti

and

Cosimo Galletti

submission deadline 15 Sep 2025 | Viewed by 224 | Submission Open

Keywords: chronic rhinosinusitis with nasal polyps; real-word evidence; otorhinolaryngology; rhinology; quality of life; therapeutic advances; monoclonal antibodies

(This special issue belongs to the Section Surgery)

Endometrial Cancer: Biomarkers and Management

edited by Maja Pakiž

submission deadline 20 Sep 2025 | 3 articles | Viewed by 3006 | Submission Open

Keywords: endometrial cancer; biomarkers; target therapy; precision medicine; access to clinical trials

(This special issue belongs to the Section Oncology)

Ophthalmology, Environment, and Lifestyle: New Pathways in Diagnosis and Treatment

edited by Jesús Merayo-Lloves and Rodrigo Martin Torres

submission deadline 20 Sep 2025 | Viewed by 118 | Submission Open

Keywords: vision science; ophthalmology; environment; lifestyle; aging

(This special issue belongs to the Section Ophthalmology)

New Developments in Diagnosis and Management of Breast Cancer

edited by Daliborca Cristina Vlad and

Ionut Marcel Cobec

submission deadline 25 Sep 2025 | 5 articles | Viewed by 5666 | Submission Open

Keywords: breast cancer; diagnosis; management; therapy; targeted therapy; triple-negative breast cancer; screening; overall survival; prognosis; immunotherapy; surgery; new techniques; staging

(This special issue belongs to the Section Oncology)

Research on Allergy, Asthma, and Clinical Immunology

edited by Constantinos Pitsios and Athanassios Sinaniotis

submission deadline 25 Sep 2025 | 3 articles | Viewed by 2582 | Submission Open

Keywords: atopy; anaphylaxis; allergic rhinitis; asthma; atopic dermatitis; food allergy; eosinophilic esophagitis; drug allergy; hymenoptera venom; angioedema; urticaria; physical urticaria; mastocytosis

(This special issue belongs to the Section Hematology and Immunology)

New Regenerative Medicine Strategies in Oral Surgery

edited by Francesco Spadari,

Matteo Pellegrini

and

Federica Pulicari

submission deadline 25 Sep 2025 | 1 articles | Viewed by 688 | Submission Open

Keywords: oral surgery; oral pathology; laser surgery; photobiomodulation

(This special issue belongs to the Section Dentistry and Oral Health)

Cutting-Edge Research into Cancer Radiotherapy

edited by Geert O.R.J. Janssens and

Radu Mitrica

submission deadline 25 Sep 2025 | Viewed by 206 | Submission Open

Keywords: FLASH radiotherapy; image-guided radiotherapy; proton therapy; real-time imaging; tumor tracking; AI linear accelerators

(This special issue belongs to the Section Oncology)

New Insights into Heart Failure

edited by

Nilima Rajpal Kundnani

and

Simona Dragan

submission deadline 30 Sep 2025 | 8 articles | Viewed by 14290 | Submission Open

Keywords: heart failure; risk factors; treatment; device therapy; biomarkers; aging; cardiovascular disease; coronary artery disease; valvular heart disease; arrythmias; stroke; COPD; cancers; liver cirrhosis

(This special issue belongs to the Section Cardiology)

Insights and Advances in Cancer Biomarkers

edited by

Krishan Jain

submission deadline 30 Sep 2025 | 6 articles | Viewed by 7013 | Submission Open

Keywords: liquid biopsies; cancer biomarkers; cellular immunotherapy; single-cell sequencing; immune biomarkers; epigenetic markers; microbiome and metabolomics; proteomics; multiomics; machine learning; generative AI

(This special issue belongs to the Section Oncology)

New Insights into Neurodevelopmental Biology and Disorders

edited by

Rekha Jagadapillai

submission deadline 30 Sep 2025 | 3 articles | Viewed by 6248 | Submission Open

Keywords: neurodevelopment; neurodevelopmental biology; neurodevelopmental disorders; autism spectrum disorders (ASDs); down syndrome; ADHD; cerebral palsy; learning disability

(This special issue belongs to the Section Neurology)

State-of-the-Art Therapeutics and Imaging in Knee Surgery

edited by

Cristian Scheau

Romica Cergan

and

Serban Dragosloveanu

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3425 | Submission Open

Keywords: knee surgery; minimally invasive techniques; regenerative medicine; diagnostic imaging modalities; MRI in knee surgery; CT and ultrasound imaging; novel surgical approaches; pharmacological treatments; patient outcomes; precision surgery; state-of-the-art therapies; clinical advancements; surgical precision; efficacy of knee treatments; robotic knee surgery; surgery-related costs; 3D-printing in knee surgery; novel surgical biomaterials; anatomical landmarks; knee morphometry

(This special issue belongs to the Section Surgery)

AI in Imaging—New Perspectives, 2nd Edition

edited by

Ivo Dumić-Čule

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3233 | Submission Open

Keywords: artificial intelligence; imaging; machine learning; radiology; ethics; big data

(This special issue belongs to the Section Surgery)

Recent Breakthroughs in the Diagnosis and Treatment of Oral Inflammatory Diseases

edited by

Liborija Lugović-Mihić

and

Ana Glavina

submission deadline 30 Sep 2025 | 2 articles | Viewed by 3078 | Submission Open

Keywords: oral inflammatory diseases; multidisciplinary; clinical manifestation; diagnosis; treatment; clinical outcome

(This special issue belongs to the Section Dentistry and Oral Health)

Towards Improved Cancer Diagnosis: New Developments in Histopathology

edited by

Ovidiu Simion Cotoi

and

Iuliu Gabriel Cocuz

submission deadline 30 Sep 2025 | 4 articles | Viewed by 2832 | Submission Open

Keywords: histopathology; cancer diagnosis; digital pathology; molecular pathology; dermatopathology

(This special issue belongs to the Section Oncology)

Updates on Prevention of Acute Heart Failure

edited by

Cristina Tudoran

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2687 | Submission Open

Keywords: acute heart failure; treatment of acute heart failure; management of acute heart failure; prevention of acute heart failure; chronic decompensated heart failure

(This special issue belongs to the Section Cardiology)

Advances in Corneal Management

edited by Sanja Masnec and Rafael I. Barraquer

submission deadline 30 Sep 2025 | 2 articles | Viewed by 2246 | Submission Open

Keywords: cornea; corneal disease; corneal transplantation; keratoconus; keratoplasty; penetrating keratoplasty; descemet stripping automated endothelial keratoplasty; deep anterior lamellar keratoplasty; descemet membrane endothelial keratoplasty; cross-linking; corneal infections; refractive surgery; photorefractive keratectomy; laser-assisted in situ keratomileusis; kerato– lenticule extraction; corneal imaging

(This special issue belongs to the Section Ophthalmology)

Hepato-Biliary-Pancreatic Surgery: Clinical Updates and Future Perspectives

edited by

Marco Massani

and

Tommaso Stecca

submission deadline 30 Sep 2025 | 3 articles | Viewed by 2218 | Submission Open

Keywords: HPB surgery; liver cancer; pancreatic cancer; biliary tract cancer

(This special issue belongs to the Section Surgery)

Surgical Approaches in Thyroid, Breast, and Other Endocrine Cancers: Advances and Challenges

edited by

Francesk Mulita

and Levan Tchabashvili

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1573 | Submission Open

Keywords: endocrine surgery; breast cancer; thyroid diseases; surgical complications

(This special issue belongs to the Section Surgery)

Magnetic Resonance in Various Diseases and Biomedical Applications

edited by

Francesco Tiralongo

and

Antonio Basile

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1314 | Submission Open

Keywords: magnetic resonance imaging; MRI; magnetic resonance imaging biomarkers; neuroimaging; cancer imaging; abdominal imaging; pelvic imaging; musculoskeletal imaging; cardiac imaging; medical imaging; diffusion imaging; tensor imaging; functional imaging; magnetic resonance angiography

(This special issue belongs to the Section Infectious Disease)

Advances in Imaging and Diagnostics in Lung Disease: A Multimodal Approach

edited by Diana Manolescu and

Emil Robert Stoicescu

submission deadline 30 Sep 2025 | 2 articles | Viewed by 1208 | Submission Open

Keywords: lung imaging; multimodal diagnostics; MRI; HRCT; lung ultrasound; pulmonary biomarkers; hybrid imaging; interstitial lung disease; AI in imaging; pulmonary medicine

(This special issue belongs to the Section Pulmonology)

Emerging Therapies for Gastric Cancer

edited by

Rui Caetano Oliveira

and

José Guilherme Tralhão

submission deadline 30 Sep 2025 | Viewed by 448 | Submission Open

Keywords: gastric cancer; oncology; therapies; individualized therapy; immunotherapy

(This special issue belongs to the Section Gastroenterology & Hepatology)

Current Advances in Foot and Ankle Surgery

edited by Min Gyu Kyung and Dong-Oh Lee

submission deadline 30 Sep 2025 | Viewed by 338 | Submission Open

Keywords: orthopedics; foot and ankle; osteoarthritis; trauma; gait analysis; advances; diagnosis; treatment; prognosis

(This special issue belongs to the Section Orthopedics)

Clinical and Surgical Updates on Bariatric Surgery

edited by

Claudio Gambardella

submission deadline 30 Sep 2025 | Viewed by 276 | Submission Open

Keywords: bariatric surgery; morbid obesity; sleeve gastrectomy; gastric bypass; surgical complications; diabetes remission; hypertension remission; hypercholesterolemia remission; GERD; de novo GERD

Atrial Fibrillation and Heart Failure Management

edited by Erika Bertella

submission deadline 30 Sep 2025 | Viewed by 206 | Submission Open

Keywords: heart failure; cardiac magnetic resonance; cardiac computed tomography; echocardiography; atrial fibrillation; electrophysiology; surgery

(This special issue belongs to the Section Cardiology)

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