Prostate cancer is one of the most lethal cancers in the male population, and accurate localization of intraprostatic lesions on MRI remains challenging. In this study, we investigated methods for improving prostate cancer segmentation on T2-weighted...
In recent years, the incidence of prostate cancer in the male population has been increasing year by year. Transrectal ultrasound (TRUS) is an important means of prostate cancer diagnosis. The accurate segmentation of the prostate in TRUS images can...
Prostate cancer is one of the most common forms of cancer globally, affecting roughly one in every eight men according to the American Cancer Society. Although the survival rate for prostate cancer is significantly high given the very high incidence...
Computer-aided detection and diagnosis (CAD) systems have the potential to improve robustness and efficiency compared to traditional radiological reading of magnetic resonance imaging (MRI). Fully automated segmentation of the prostate is a crucial s...
Segmentation of the prostate gland from magnetic resonance images is rapidly becoming a standard of care in prostate cancer radiotherapy treatment planning. Automating this process has the potential to improve accuracy and efficiency. However, the pe...
Automatic and accurate prostate segmentation is an essential prerequisite for assisting diagnosis and treatment, such as guiding biopsy procedures and radiation therapy. Therefore, this paper proposes a cascaded dual attention network (CDA-Net) for a...
Introduction: External radiotherapy is a major treatment for localized prostate cancer (PCa). Dose escalation to the whole prostate gland increases biochemical relapse-free survival but also acute and late toxicities. Dose escalation to the dominant...
We aimed to compare the performance and interobserver agreement of radiologists manually segmenting images or those assisted by automatic segmentation. We further aimed to reduce interobserver variability and improve the consistency of radiomics feat...
Prostate segmentations are required for an ever-increasing number of medical applications, such as image-based lesion detection, fusion-guided biopsy and focal therapies. However, obtaining accurate segmentations is laborious, requires expertise and,...
Magnetic resonance imaging (MRI) has a growing role in the clinical workup of prostate cancer. However, manual three-dimensional (3D) segmentation of the prostate is a laborious and time-consuming task. In this scenario, the use of automated algorith...
Background: Robot-assisted radical prostatectomy (RARP) is a common treatment option for prostate cancer. A 3D model for surgical guidance can improve surgical outcomes. Manual expert radiologist segmentation of the prostate and tumor in prostate MRI...
Magnetic Resonance Imaging is increasing in importance in prostate cancer diagnosis due to the high accuracy and quality of the examination procedure. However, this process requires a time-consuming analysis of the results. Currently, machine vision...
The precise segmentation of different regions of the prostate is crucial in the diagnosis and treatment of prostate-related diseases. However, the scarcity of labeled prostate data poses a challenge for the accurate segmentation of its different regi...
Magnetic Resonance Imaging-based prostate segmentation is an essential task for adaptive radiotherapy and for radiomics studies whose purpose is to identify associations between imaging features and patient outcomes. Because manual delineation is a t...
Medical support systems used to assist in the diagnosis of prostate lesions generally related to prostate segmentation is one of the majors focus of interest in recent literature. The main problem encountered in the diagnosis of a prostate study is t...
The accurate segmentation of prostate cancer (PCa) from multiparametric MRI is crucial in clinical practice for guiding biopsy and treatment planning. Existing automated methods often lack the necessary accuracy and robustness in localizing PCa, wher...
The manual delineation of region of interest (RoI) in 3D magnetic resonance imaging (MRI) of the prostate is time-consuming and subjective. Correct identification of prostate tissue is helpful to define a precise RoI to be used in CAD systems in clin...
Volume of interest segmentation is an essential step in computer-aided detection and diagnosis (CAD) systems. Deep learning (DL)-based methods provide good performance for prostate segmentation, but little is known about the reproducibility of these...
Background/Objective: High-frequency micro-ultrasound (micro-US) offers real-time, high-resolution imaging for prostate cancer. Although artificial intelligence (AI) has shown potential in enhancing micro-US interpretation, a comprehensive review of...
Detailed evaluation of prostate cancer glands is an essential yet labor-intensive step in grading prostate cancer. Gland segmentation can serve as a valuable preliminary step for machine-learning-based downstream tasks, such as Gleason grading, patie...
Objective: The objective of this study was to develop and assess the clinical feasibility of auto-segmentation and auto-planning methodologies for automated radiotherapy in prostate cancer. Methods: A total of 166 patients were used to train a 3D Une...
Prostate imaging analysis is difficult in diagnosis, therapy, and staging of prostate cancer. In clinical practice, Magnetic Resonance Imaging (MRI) is increasingly used thanks to its morphologic and functional capabilities. However, manual detection...
Prostate cancer (PCa) is one of the most common tumors diagnosed in men worldwide, with approximately 1.7 million new cases expected by 2030. Most cancerous lesions in PCa are located in the peripheral zone (PZ); therefore, accurate identification of...
Prostate cancer, a prevalent malignancy affecting males globally, underscores the critical need for precise prostate segmentation in diagnostic imaging. However, accurate delineation via MRI still faces several challenges: (1) The distinction of the...
In this paper, we develop an optimised state-of-the-art 2D U-Net model by studying the effects of the individual deep learning model components in performing prostate segmentation. We found that for upsampling, the combination of interpolation and co...
Background/Objective: Longitudinal in vivo studies of murine xenograft models are widely utilized in oncology to study cancer biology and develop therapies. Magnetic resonance imaging (MRI) of these tumors is an invaluable tool for monitoring tumor g...
Recent advances in computer-aided detection via deep learning (DL) now allow for prostate cancer to be detected automatically and recognized with extremely high accuracy, much like other medical diagnoses and prognoses. However, researchers are still...
U-Net, based on a deep convolutional network (CNN), has been clinically used to auto-segment normal organs, while still being limited to the planning target volume (PTV) segmentation. This work aims to address the problems in two aspects: 1) apply on...
High-resolution intraoperative PET/CT specimen imaging, coupled with prostate-specific membrane antigen (PSMA) molecular targeting, holds great potential for the rapid ex vivo identification of disease localizations in high-risk prostate cancer patie...
Background: PSMA PET/CT imaging has become a cornerstone in the management of prostate cancer, particularly in the setting of biochemical recurrence (BCR). While semi-quantitative parameters such as SUVmean have been evaluated as prognostic biomarker...
Prostate brachytherapy is a treatment for prostate cancer; during the planning of the procedure, ultrasound images of the prostate are taken. The prostate must be segmented out in each of the ultrasound images, and to assist with the procedure, an au...
Prostate cancer is a global health concern, and early diagnosis plays a vital role in improving the survival rate. Accurate segmentation is a key step in the automated diagnosis of prostate cancer; however, manual segmentation remains time-consuming...
In this paper, we present an evaluation of four encoder–decoder CNNs in the segmentation of the prostate gland in T2W magnetic resonance imaging (MRI) image. The four selected CNNs are FCN, SegNet, U-Net, and DeepLabV3+, which was originally pr...
Accurate segmentation for transrectal ultrasound imaging (TRUS) is often a challenging medical image processing task. The problem of weak boundary between adjacent prostate tissue and non-prostate tissue, and high similarity between artifact area and...
Over the past decade, the development of computer-aided detection tools for medical image analysis has seen significant advancements. However, tasks such as the automatic differentiation of tissues or regions in medical images remain challenging. Mag...
Accurate prostate volume estimation is crucial for effective prostate disease management. Ultrasound (US) imaging, particularly transrectal ultrasound, offers a cost-effective and rapid assessment. However, US images often suffer from artifacts and p...
Stability analysis remains a fundamental step in developing a successful imaging biomarker to personalize oncological strategies. This study proposes an in silico contour generation method for simulating segmentation variations to identify stable rad...
Background: Radiomics shows promising results in supporting the clinical decision process, and much effort has been put into its standardization, thus leading to the Imaging Biomarker Standardization Initiative (IBSI), that established how radiomics...
Background/Objectives: We assessed the influence of local patients and clinical characteristics on the performance of commercial deep learning (DL) segmentation models for head-and-neck (HN), breast, and prostate cancers. Methods: Clinical computed t...
In this study, a multistage segmentation technique is proposed that identifies cancerous cells in prostate tissue samples. The benign areas of the tissue are distinguished from the cancerous regions using the texture of glands. The texture is modeled...
Background: Precise delineation of the rectum is crucial in treatment planning for cancers in the pelvic region, such as prostate and cervical cancers. Manual segmentation is also still time-consuming and suffers from inter-observer variability. Sinc...
Multiparametric magnetic resonance imaging (mpMRI) of the prostate is used by radiologists to identify, score, and stage abnormalities that may correspond to clinically significant prostate cancer (CSPCa). Automatic assessment of prostate mpMRI using...
This paper presents the PRONOBIS project, an ultrasound-only, robotically assisted, deep learning-based system for prostate scanning and biopsy treatment planning. The proposed system addresses the challenges of precise prostate segmentation, reconst...
Background: We investigated the feasibility of a deep learning algorithm (DLA) based on apparent diffusion coefficient (ADC) maps for the segmentation and discrimination of clinically significant cancer (CSC, Gleason score ≥ 7) from non-CSC in pat...
In prostate cancer, fusion biopsy, which couples magnetic resonance imaging (MRI) with transrectal ultrasound (TRUS), poses the basis for targeted biopsy by allowing the comparison of information coming from both imaging modalities at the same time....
A commercial deep learning (DL)-based automated segmentation tool (AST) for computed tomography (CT) is evaluated for accuracy and efficiency gain within prostate cancer patients. Thirty patients from six clinics were reviewed with manual- (MC), auto...
For prostate cancer patients, large organ deformations occurring between radiotherapy treatment sessions create uncertainty about the doses delivered to the tumor and surrounding healthy organs. Segmenting those regions on cone beam CT (CBCT) scans a...
The Gleason score (GS) is essential in categorizing prostate cancer risk using biopsy. The aim of this study was to propose a two-class GS classification (< and ≥GS 7) methodology using a three-dimensional convolutional neural network with sema...
As yet, there is no systematic review focusing on benefits and issues of commercial deep learning-based auto-segmentation (DLAS) software for prostate cancer (PCa) radiation therapy (RT) planning despite that NRG Oncology has underscored such necessi...
Prostate cancer (PCa) is a significant health concern for men worldwide, where early detection and effective diagnosis can be crucial for successful treatment. Multiparametric magnetic resonance imaging (mpMRI) has evolved into a significant imaging...
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