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228 Results Found

  • Perspective
  • Open Access
8 Citations
5,885 Views
10 Pages

Medical product sponsors are encouraged to include the patient perspective in their medical product development strategy to inform product design, augment regulatory submissions, argue for alternative clinical trial designs, or to support indications...

  • Communication
  • Open Access
30 Citations
11,439 Views
23 Pages

Phage Therapy in Germany—Update 2023

  • Christian Willy,
  • Joachim J. Bugert,
  • Annika Y. Classen,
  • Li Deng,
  • Anja Düchting,
  • Justus Gross,
  • Jens A. Hammerl,
  • Imke H. E. Korf,
  • Christian Kühn and
  • Simone Lieberknecht-Jouy
  • + 10 authors

20 February 2023

Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally and in Germany. Here, we provide an overview of the current situation (2023) of applied phage therapy and supporting research in Germany. The authors, an int...

  • Article
  • Open Access
2 Citations
4,022 Views
15 Pages

6 February 2020

Coordination is described as a widespread function emerging in relation to policy plans inducing collaboration between different sectors, organizations and professions. This paper suggests seeing the implementation phase as a translation process, one...

  • Review
  • Open Access
3 Citations
3,172 Views
22 Pages

Antifungal Policy and Practice Across Five Countries: A Qualitative Review

  • David W. Denning,
  • John R. Perfect,
  • Neda Milevska-Kostova,
  • Artes Haderi,
  • Hannah Armstrong,
  • Maarten C. Hardenberg,
  • Emily Chavez,
  • Bruce Altevogt,
  • Patrick Holmes and
  • Jalal A. Aram

19 February 2025

The burden of invasive fungal infections (IFIs) is increasing worldwide. National, regional, and local policies on IFI management should respond to the changing landscape. We assessed antifungal policies from five countries of varying size, IFI burde...

  • Review
  • Open Access
17 Citations
4,488 Views
15 Pages

4 February 2023

Visits of chronically ill patients account for 80% of primary care consultations. Approximately 15–38% of patients have three or more chronic diseases, and 30% of hospitalisations result from the deteriorating clinical condition of these patien...

  • Review
  • Open Access
2 Citations
2,823 Views
15 Pages

Understanding Diversity of Policies, Functionalities, and Operationalization of Immunization Information Systems and Their Impact: A Targeted Review of the Literature

  • Elizabeth A. Donckels,
  • Luke Cunniff,
  • Nina Regenold,
  • Kaitlyn Esselman,
  • Erik Muther,
  • Alexandra Bhatti and
  • Amanda L. Eiden

15 July 2023

The COVID-19 pandemic has focused attention on the use of immunization information systems (IIS) to record and consolidate immunization records from a variety of sources to generate comprehensive patient immunization histories. Operationalization of...

  • Communication
  • Open Access
7 Citations
2,877 Views
17 Pages

The Italian Government planned to invest €15 billion of European funds on National Health Service digitalization and primary care enhancement. The critical burden brought by the pandemic upon hospital care mean these investments could no longer...

  • Article
  • Open Access
3 Citations
2,630 Views
17 Pages

The Predictability of the Dental Practitioner in a Volatile Healthcare System: A 25-Year Study of Dental Care Policies in Romania (1999–2023)

  • Ana Cernega,
  • Dana Galieta Mincă,
  • Florentina Ligia Furtunescu,
  • Ciprian-Paul Radu,
  • Simona Pârvu and
  • Silviu-Mirel Pițuru

26 January 2025

Background/Objectives: This paper brings to light the results of extensive research on the dimension of dental care in Romania in terms of priorities and policies defined at the governmental level for a 25-year period (1999–2023). This research...

  • Article
  • Open Access
819 Views
8 Pages

Public Policies and Type of Insurance Are Associated with the Burden of Bladder Cancer – Related Inpatient Health Care in Chile: A Two-Decade Analysis

  • Ignacio Eltit,
  • Joaquín Cristi,
  • Iris Delgado,
  • Paula Huerta,
  • Sergio Fuentes,
  • Alberto Bustamante and
  • Mario I. Fernández

19 July 2023

Objective: To quantify changes in the burden of bladder cancer (BC) inpatient health care in Chile between 2001 and 2019, focusing on the impact of public policies and the type of medical insurance (public or private) held by patients. Methods: We re...

  • Article
  • Open Access
12 Citations
4,858 Views
14 Pages

Rural Healthcare Enterprises in the Vortex of COVID-19: The Impact of Public Policies on the Internal and External Environment

  • Nikolaos Apostolopoulos,
  • Sotiris Apostolopoulos,
  • Ilias Makris and
  • Stavros Stavroyiannis

13 August 2021

The public policies implemented in order to contain the spread of COVID-19 in the community have created issues both in the internal and the external environments of the Greek rural healthcare enterprises. This study aimed to investigate the full ext...

  • Systematic Review
  • Open Access
2 Citations
2,883 Views
20 Pages

Optimizing Surgical Care Amidst COVID-19: A Scoping Review of Practices and Policies

  • Nasser A. N. Alzerwi,
  • Musaed Rayzah,
  • Ahmad K. Alnemare and
  • Ahmed M. E. Elkhalifa

31 December 2023

Background: The coronavirus disease (COVID-19) pandemic significantly disrupted surgical care worldwide, affecting different specialties in various ways. Lockdowns, surges in COVID-19 cases, and changes in hospital policies notably impacted patient a...

  • Perspective
  • Open Access
3 Citations
2,428 Views
12 Pages

Nutrition-Focused Quality Improvement Programs in Pediatric Care

  • Amy R. Sharn,
  • Wendy Phillips,
  • John T. Stutts,
  • Mary Kaminski,
  • Amy Shepps and
  • Mary Beth Arensberg

26 November 2024

Nutrition is fundamental to a child’s growth and development. However, nutritional health is often compromised by acute and chronic conditions and treatments that can commonly result in malnutrition. Malnutrition encompasses undernutrition and...

  • Article
  • Open Access
2 Citations
3,033 Views
10 Pages

31 July 2023

Paediatric homecare is an advancing field of healthcare, bringing care direct to patients in their own homes. Risk management is an integral component of homecare services, including incident and risk assessment management. The objective of the study...

  • Review
  • Open Access
193 Citations
80,298 Views
15 Pages

Nurses’ Adherence to Patient Safety Principles: A Systematic Review

  • Mojtaba Vaismoradi,
  • Susanna Tella,
  • Patricia A. Logan,
  • Jayden Khakurel and
  • Flores Vizcaya-Moreno

Background: Quality-of-care improvement and prevention of practice errors is dependent on nurses’ adherence to the principles of patient safety. Aims: This paper aims to provide a systematic review of the international literature, to synthesise...

  • Article
  • Open Access
7 Citations
3,355 Views
21 Pages

Current research on the built environment and medical choice focuses mainly on the construction and optimization of medical service systems from the perspective of supply. There is a lack of in-depth research on medical choice from the perspective of...

  • Article
  • Open Access
13 Citations
4,024 Views
8 Pages

Hospitalisation Cost of Patients with Diabetic Foot Ulcers in Valencia (Spain) in the Period 2009–2013: A Retrospective Descriptive Analysis

  • Pilar Nieto-Gil,
  • Ana Belen Ortega-Avila,
  • Manuel Pardo-Rios,
  • Manuel Cobo-Najar,
  • Carlos Blasco-Garcia and
  • Gabriel Gijon-Nogueron

Ulcers are the main cause of hospitalisation and clinical complications in patients with diabetes. We analyse the length and cost of hospital stay of patients with diabetic foot ulcers, taking into consideration that hospitalisation and, if necessary...

  • Commentary
  • Open Access
1,050 Views
4 Pages

When Jurisdictional Boundaries Become Barriers to Good Patient Care

  • J. Stephen,
  • K. Fergus,
  • S. Sellick,
  • M. Speca,
  • J. Taylor–Brown,
  • J. Turner,
  • K. Collie,
  • D. McLeod and
  • A. Rojubally

1 February 2013

Canada is a pioneer in remote cancer care delivery to underserved populations; however, it is trailing behind on policies that would support clinicians in providing care using distance technologies. The current policy framework is disjointed, and dis...

  • Review
  • Open Access
99 Citations
16,876 Views
20 Pages

The Global Burden of Valvular Heart Disease: From Clinical Epidemiology to Management

  • Gloria Santangelo,
  • Francesca Bursi,
  • Andrea Faggiano,
  • Silvia Moscardelli,
  • Pasquale Simone Simeoli,
  • Marco Guazzi,
  • Roberto Lorusso,
  • Stefano Carugo and
  • Pompilio Faggiano

10 March 2023

Valvular heart disease is a leading cause of cardiovascular morbidity and mortality and a major contributor of symptoms and functional disability. Knowledge of valvular heart disease epidemiology and a deep comprehension of the geographical and tempo...

  • Article
  • Open Access
4 Citations
3,772 Views
14 Pages

8 December 2021

While current opioid prescribing guidelines highlight a dose-response relationship between therapeutic management and overdose risk, other concurrent risk factors have also been identified. However, there is little data in assessing the relationship...

  • Article
  • Open Access
14 Citations
6,084 Views
16 Pages

An Innovative Approach to Designing Digital Health Solutions Addressing the Unmet Needs of Obese Patients in Europe

  • Roberta Patalano,
  • Vincenzo De Luca,
  • Jess Vogt,
  • Strahil Birov,
  • Lucia Giovannelli,
  • Giuseppe Carruba,
  • Claudia Pivonello,
  • Veli Stroetmann,
  • Maria Triassi and
  • Annamaria Colao
  • + 1 author

According to the World Health Organization (WHO), the worldwide obesity rate has tripled since 1975. In Europe, more than half of the population is overweight and obese. Around 2.8 million people die each year worldwide as a result of conditions link...

  • Article
  • Open Access
1 Citations
3,288 Views
26 Pages

A Qualitative Evaluation of the Australian Community Pharmacy Agreement

  • John K. Jackson,
  • Betty B. Chaar,
  • Carl M. Kirkpatrick,
  • Shane L. Scahill and
  • Michael Mintrom

18 December 2023

The Australian Federal Government’s Community Pharmacy Agreement (Agreement), initiated in 1990 and renegotiated every five years with a pharmacy owners’ organisation, is the dominant policy directing community pharmacy. We studied the ex...

  • Article
  • Open Access
5 Citations
4,521 Views
12 Pages

There is an association between alcohol consumption and injuries in Latin America and the Caribbean. This cross-sectional study explores the socio-contextual factors of alcohol-related injuries in Trinidad and Tobago. Data on drinking patterns, injur...

  • Communication
  • Open Access
1 Citations
1,399 Views
9 Pages

Background/Objectives: Global patient satisfaction is vital for healthcare quality, yet no survey enables effective cross-country comparisons. Existing tools are limited in scope, focusing on aspects like Patient-Reported Experience Measures, Patient...

  • Review
  • Open Access
3 Citations
3,973 Views
21 Pages

20 December 2024

Singapore’s national myopia prevention efforts have largely focused on school vision screening and public education on outdoor activities in the past two decades. Given the emergence of evidence-based myopia interventions, this policy review an...

  • Article
  • Open Access
2 Citations
2,417 Views
13 Pages

Variation in Communication and Family Visiting Policies in Italian Intensive Care Units during the COVID-19 Pandemic: A Secondary Analysis of the COVISIT International Survey

  • Barbara Simone,
  • Mariachiara Ippolito,
  • Pasquale Iozzo,
  • Francesco Zuccaro,
  • Antonino Giarratano,
  • Maurizio Cecconi,
  • Alexis Tabah and
  • Andrea Cortegiani

24 February 2023

Background: During COVID-19 pandemic, restrictions to in-person visiting of caregivers to patients admitted to intensive care units (ICU) were applied in many countries. Our aim was to describe the variations in communication and family visiting poli...

  • Review
  • Open Access
14 Citations
3,586 Views
15 Pages

Determinants of Outcomes of Acute Kidney Injury: Clinical Predictors and Beyond

  • Emaad M. Abdel-Rahman,
  • Faruk Turgut,
  • Jitendra K. Gautam and
  • Samir C. Gautam

11 March 2021

Acute kidney injury (AKI) is a common clinical syndrome characterized by rapid impairment of kidney function. The incidence of AKI and its severe form AKI requiring dialysis (AKI-D) has been increasing over the years. AKI etiology may be multifactori...

  • Review
  • Open Access
2 Citations
3,233 Views
7 Pages

1 February 2021

The article presents concepts and the Public Health Policy University of Lisbon Lab project to answer questions about the macro-environment of cancer and loneliness. Although the biomedical model has considered the disease’s general symptoms, it take...

  • Article
  • Open Access
7 Citations
3,825 Views
9 Pages

Considering Patients’ Empowerment in Chronic Care Management: A Cross-Level Approach

  • Caroline Tilkin,
  • Mélanie De Winter,
  • Frédéric Ketterer,
  • Anne-Marie Etienne,
  • Marc Vanmeerbeek and
  • Frédéric Schoenaers

This paper consists of an analysis of the concept of empowerment—which is often defined as a key issue in health care—at the macro, meso, and micro levels by focusing on health care reform in Belgium. Three research teams collected data a...

  • Perspective
  • Open Access
92 Citations
16,259 Views
28 Pages

27 February 2025

Background/Objectives: Artificial intelligence (AI) is transforming healthcare, enabling advances in diagnostics, treatment optimization, and patient care. Yet, its integration raises ethical, regulatory, and societal challenges. Key concerns include...

  • Article
  • Open Access
8 Citations
4,287 Views
14 Pages

Challenges in Accessing and Delivering Maternal and Child Health Services during the COVID-19 Pandemic: A Cross-Sectional Rapid Survey from Six States of India

  • Saurabh Sharma,
  • Sumit Aggarwal,
  • Ragini Kulkarni,
  • Dinesh Kumar,
  • Bijaya Kumar Mishra,
  • Gaurav Raj Dwivedi,
  • K. Rekha Devi,
  • Raja Sriswan Mamidi,
  • Khangembam Jitenkumar Singh and
  • Lucky Singh
  • + 30 authors

Background/Objectives: Globally, the COVID-19 pandemic and its prevention and control policies have impacted maternal and child health (MCH) services. This study documents the challenges faced by patients in accessing MCH services, and the experience...

  • Review
  • Open Access
13 Citations
3,391 Views
14 Pages

Strategies to Overcome HLA Sensitization and Improve Access to Retransplantation after Kidney Graft Loss

  • Rita Leal,
  • Clara Pardinhas,
  • António Martinho,
  • Helena Oliveira Sá,
  • Arnaldo Figueiredo and
  • Rui Alves

28 September 2022

An increasing number of patients waitlisted for kidney transplantation have a previously failed graft. Retransplantation provides a significant improvement in morbidity, mortality, and quality of life when compared to dialysis. However, HLA sensitiza...

  • Article
  • Open Access
13 Citations
4,051 Views
12 Pages

Genomic and Metabolomic Landscape of Right-Sided and Left-Sided Colorectal Cancer: Potential Preventive Biomarkers

  • Ming-Wei Su,
  • Chung-Ke Chang,
  • Chien-Wei Lin,
  • Hou-Wei Chu,
  • Tsen-Ni Tsai,
  • Wei-Chih Su,
  • Yen-Cheng Chen,
  • Tsung-Kun Chang,
  • Ching-Wen Huang and
  • Hsiang-Lin Tsai
  • + 4 authors

3 February 2022

Colorectal cancer (CRC) is the third most common cancer worldwide. The incidence and mortality rates of CRC are significantly higher in Taiwan than in other developed countries. Genes involved in CRC tumorigenesis differ depending on whether the tumo...

  • Article
  • Open Access
23 Citations
4,354 Views
9 Pages

Health Policies in Romania to Reduce the Mortality Caused by Cardiovascular Diseases

  • Mihaela Simionescu,
  • Svitlana Bilan,
  • Beata Gavurova and
  • Elena-Nicoleta Bordea

Cardiovascular diseases (CVDs) are the main cause of death in Romania. The objective of the paper is to explain the number of deaths caused by the diseases of circulatory system in relation to health expenditures per capita, the number of public hosp...

  • Article
  • Open Access
1 Citations
1,707 Views
26 Pages

9 June 2025

This study investigates the evolutionary game dynamics of medical knowledge sharing (KS) among Chinese hospitals under government regulation, focusing on the strategic interactions between general hospitals, community health service centers, and gove...

  • Article
  • Open Access
12 Citations
6,196 Views
10 Pages

The current study aimed to examine patient experience scores and differences in the scores based on the region and nurse staffing level of hospitals as well as to verify the effect of nurse-related patient experience scores on the overall rating of h...

  • Article
  • Open Access
19 Citations
8,846 Views
16 Pages

Lifestyle Medicine Reimbursement: A Proposal for Policy Priorities Informed by a Cross-Sectional Survey of Lifestyle Medicine Practitioners

  • Kelly J. Freeman,
  • Meagan L. Grega,
  • Susan M. Friedman,
  • Padmaja M. Patel,
  • Ron W. Stout,
  • Thomas M. Campbell,
  • Michelle L. Tollefson,
  • Liana S. Lianov,
  • Kaitlyn R. Pauly and
  • Kathryn J. Pollard
  • + 1 author

Lifestyle medicine (LM) is a rapidly emerging clinical discipline that focuses on intensive therapeutic lifestyle changes to treat chronic disease, often producing dramatic health benefits. In spite of these well-documented benefits of LM approaches...

  • Guidelines
  • Open Access
4 Citations
3,880 Views
12 Pages

A Guide to Implementing Immune Checkpoint Inhibitors within a Cancer Program: Experience from a Large Canadian Community Centre

  • Parneet K. Cheema,
  • Marco A. J. Iafolla,
  • Massey Nematollahi,
  • FeRevelyn Berco,
  • Deepanjali Kaushik,
  • Priscilla Matthews,
  • William R. Raskin,
  • Kirstin A. Perdrizet,
  • Shaan Dudani and
  • Juhi Husain
  • + 4 authors

4 February 2022

The increased use of immune checkpoint inhibitors across cancer programs has created the need for standardized patient assessment, education, monitoring, and management of immune-related adverse events (irAEs). At William Osler Health System in Bramp...

  • Commentary
  • Open Access
1 Citations
1,545 Views
7 Pages

18 November 2024

This brief commentary describes the reflections on a fundamental question by the Public Interest Group on Cancer Research, a successful academic-community partnership focused on cancer research, education, public engagement, and advocacy in Canada&rs...

  • Perspective
  • Open Access
1 Citations
3,005 Views
12 Pages

29 June 2024

With global chronic disease rates on the rise, diet and nutrition remain pivotal yet under-appreciated aspects of healthcare, including in pharmacy practice. This perspective paper delves into how current United States health policies support nutriti...

  • Review
  • Open Access
8 Citations
2,333 Views
14 Pages

Striving for Equity: Examining Health Disparities in Urologic Oncology

  • Dhruv Puri,
  • Kshitij Pandit,
  • Noah Choi,
  • Brent S. Rose,
  • Rana R. McKay and
  • Aditya Bagrodia

22 October 2024

Health disparities in urologic oncology, particularly in prostate, bladder, kidney, and testicular cancers, significantly impact patient outcomes across different demographic groups. This narrative review aims to investigate the extent and drivers of...

  • Article
  • Open Access
7 Citations
10,912 Views
17 Pages

9 August 2024

This study explores the ethical and legal challenges faced by nurses in caring for older adults with multimorbidities, focusing on issues related to patient autonomy, polypharmacy, and end-of-life care. Through semi-structured interviews with 15 nurs...

  • Review
  • Open Access
4 Citations
979 Views
6 Pages

29 September 2014

Many international organizations are struggling today to coordinate limited economic and human resources in support of governments’ efforts to advance public health around the world. The United Nations and the World Health Organization, along with ot...

  • Systematic Review
  • Open Access
2,818 Views
31 Pages

Smart Contracts, Blockchain, and Health Policies: Past, Present, and Future

  • Kenan Kaan Kurt,
  • Meral Timurtaş,
  • Sevcan Pınar,
  • Fatih Ozaydin and
  • Serkan Türkeli

2 October 2025

The integration of blockchain technology into healthcare systems has emerged as a technical solution for enhancing data security, protecting privacy, and improving interoperability. Blockchain-based smart contracts offer reliability, transparency, an...

  • Article
  • Open Access
42 Citations
5,396 Views
25 Pages

18 October 2018

The sharing of electronic health records (EHR) in cloud servers is an increasingly important development that can improve the efficiency of medical systems. However, there are several concerns focusing on the issues of security and privacy in EHR sys...

  • Feature Paper
  • Review
  • Open Access
13 Citations
8,128 Views
11 Pages

3 April 2023

The use of digital health technologies, including telemedicine and teledentistry, has become a necessity in healthcare due to the SARS-CoV-19 pandemic. These technologies allow for the reduction of the workload of healthcare providers and the improve...

  • Article
  • Open Access
13 Citations
4,495 Views
19 Pages

27 October 2023

Coercion of service users/patients when receiving care and treatment has been a serious dilemma for mental health services since at least the 18th century, and the debate about how best to minimise or even eradicate compulsion remains intense. Coerci...

  • Article
  • Open Access
2 Citations
3,323 Views
11 Pages

Athletic Trainers’ Perceptions of and Experience with Social Determinants of Health

  • Kelsey J. Picha,
  • Cailee E. Welch Bacon,
  • R. Curt Bay,
  • Joy H. Lewis and
  • Alison R. Snyder Valier

The role that social determinants of health (SDHs) play in athletic healthcare is gaining attention, yet little is known about athletic trainers’ (ATs) perceptions of and encounters with the impact of SDHs. The purpose of this study was to eval...

  • Article
  • Open Access
3 Citations
2,509 Views
8 Pages

Hepatitis-C-Related Hepatocellular Carcinoma, Still a Relevant Etiology beyond a Hepatitis C Infection Cure

  • Elena Vargas-Accarino,
  • Mónica Higuera,
  • María Buti and
  • Beatriz Mínguez

16 April 2024

Background: In the past decades, global changes, including hepatitis B vaccination, hepatitis B and C antiviral therapies, and the increasing prevalence of steatotic liver disease, have influenced the landscape of liver cancer etiologies. Methods: We...

  • Article
  • Open Access
6 Citations
3,698 Views
12 Pages

Palliative care (PC) is an important alternative treatment for patients with chronic diseases, particularly for those in the later stages of disease progression. This is because these diseases are often irreversible, with progressive worsening of sym...

  • Article
  • Open Access
27 Citations
7,121 Views
12 Pages

The Association between Migraine and Types of Sleep Disorder

  • Seung Ju Kim,
  • Kyu-Tae Han,
  • Suk-Yong Jang,
  • Ki-Bong Yoo and
  • Sun Jung Kim

Background: Migraines gradually increase year by year, as does its burden. Management and prevention are needed to reduce such burdens. Previous studies have suggested that daily health behaviors can cause migraines. Sleep is a substantial part of da...

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