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40 Results Found

  • Article
  • Open Access
10 Citations
9,058 Views
19 Pages

Causality between Terrorism and FDI in Tourism: Evidence from Panel Data

  • Maja Nikšić Radić,
  • Daniel Dragičević and
  • Marina Barkiđija Sotošek

The aim of this research was to examine the causal link between terrorism and FDI in tourism on the example of a panel of 50 countries for the period from 2000 to 2016. Other control variables were included in order to ensure the validity of the resu...

  • Article
  • Open Access
10 Citations
7,450 Views
23 Pages

18 December 2013

The European sovereign-debt crisis began in Greece when the government announced in December, 2009, that its debt reached 121% of GDP (or 300 billion euros) and its 2009 budget deficit was 12.7% of GDP, four times the level allowed by the Maastricht...

  • Article
  • Open Access
3 Citations
3,331 Views
30 Pages

26 April 2025

This study explores the intricate interconnections between greenwashing, environmental performance (ESG), firm-specific characteristics, board composition, firm age, size, leverage, carbon emissions (CO2), and financial performance. By applying a com...

  • Article
  • Open Access
3 Citations
5,606 Views
23 Pages

20 October 2020

Labor productivity has an essential role in creating a more sustainable labor market platform, leading to better economic sustainability. However, the sluggish growth in labor productivity in Malaysia could hinder the vision in realizing the status o...

  • Correction
  • Open Access
4,525 Views
1 Page

27 March 2014

It has come to our attention that due to an error in producing the PDF version of the paper [1], doi:10.3390/socsci2040318, website: http://www.mdpi.com/2076-0760/2/4/318, some of the figures are displayed incorrectly. [...]

  • Article
  • Open Access
8 Citations
3,030 Views
21 Pages

30 August 2022

This study examines the effects of fiscal policy on private expenditure using a panel VAR for the sample of 60 developing countries from 1990 to 2020. The VAR panel model framework was used to focus on the disaggregated government expenditures which...

  • Article
  • Open Access
60 Citations
7,971 Views
21 Pages

Capture and Detection of Circulating Glioma Cells Using the Recombinant VAR2CSA Malaria Protein

  • Sara R. Bang-Christensen,
  • Rasmus S. Pedersen,
  • Marina A. Pereira,
  • Thomas M. Clausen,
  • Caroline Løppke,
  • Nicolai T. Sand,
  • Theresa D. Ahrens,
  • Amalie M. Jørgensen,
  • Yi Chieh Lim and
  • Louise Goksøyr
  • + 13 authors

28 August 2019

Diffuse gliomas are the most common primary malignant brain tumor. Although extracranial metastases are rarely observed, recent studies have shown the presence of circulating tumor cells (CTCs) in the blood of glioma patients, confirming that a subse...

  • Communication
  • Open Access
8 Citations
3,044 Views
8 Pages

Identification of Distinctive Primary Metabolites Influencing Broccoli (Brassica oleracea, var. Italica) Taste

  • Sergio Chevilly,
  • Laura Dolz-Edo,
  • José Blanca,
  • Lynne Yenush and
  • José M. Mulet

11 January 2023

Broccoli (Brassica oleracea L. var. Italica Plenck) is a cruciferous crop that is considered to be a good source of micronutrients. Better taste is a main objective for breeding, as consumers are demanding novel cultivars suited for a healthy di...

  • Article
  • Open Access
15 Citations
13,970 Views
23 Pages

Labor Costs and Foreign Direct Investment: A Panel VAR Approach

  • Bahar Bayraktar-Sağlam and
  • Selin Sayek Böke

26 September 2017

This paper examines the endogenous interaction between labor costs and Foreign Direct Investment (FDI) in the OECD countries via the Panel VAR approach under system GMM estimates for the period 1995–2009. The available data allows identifying the rel...

  • Article
  • Open Access
3 Citations
1,873 Views
21 Pages

A Panel-Agnostic Strategy ‘HiPPo’ Improves Diagnostic Efficiency in the UK Genomic Medicine Service

  • Eleanor G. Seaby,
  • N. Simon Thomas,
  • David Hunt,
  • Diana Baralle,
  • Heidi L. Rehm,
  • Anne O’Donnell-Luria and
  • Sarah Ennis

15 December 2023

Genome sequencing is available as a clinical test in the UK through the Genomic Medicine Service (GMS). The GMS analytical strategy predominantly filters genome data on preselected gene panels. Whilst this reduces variants requiring assessment by rep...

  • Article
  • Open Access
4 Citations
3,835 Views
11 Pages

PhenGenVar: A User-Friendly Genetic Variant Detection and Visualization Tool for Precision Medicine

  • JaeMoon Shin,
  • Junbeom Jeon,
  • Dawoon Jung,
  • Kiyong Kim,
  • Yun Joong Kim,
  • Dong-Hoon Jeong and
  • JeeHee Yoon

12 June 2022

Precision medicine has been revolutionized by the advent of high-throughput next-generation sequencing (NGS) technology and development of various bioinformatic analysis tools for large-scale NGS big data. At the population level, biomedical studies...

  • Article
  • Open Access
1,194 Views
14 Pages

Clinical Application of a Customized Gene Panel for Identifying Autism Spectrum Disorder-Associated Variants

  • Vittoria Greco,
  • Donatella Greco,
  • Simone Treccarichi,
  • Maria Bottitta,
  • Pinella Failla,
  • Antonino Musumeci,
  • Carla Papa,
  • Valeria Chiavetta,
  • Francesco Calì and
  • Mirella Vinci

14 July 2025

Background and Objectives: Autism spectrum disorder (ASD) is a neurodevelopmental disorder that belong to genetic and epigenetic mechanism. Despite the recent advantages in next-generation sequencing (NGS) technology, ASD etiology is still unclear. M...

  • Article
  • Open Access
6 Citations
4,154 Views
20 Pages

23 September 2022

This study re-examined the effect of official development assistance (ODA) of five major donor countries (France, Germany, Japan, the United Kingdom, and the United States) on foreign direct investment (FDI) using panel data from 2003 to 2020. In add...

  • Article
  • Open Access
7 Citations
5,526 Views
7 Pages

Next-Generation Sequencing of Connective Tissue Genes in Patients with Classical Ehlers-Danlos Syndrome

  • Anna Junkiert-Czarnecka,
  • Maria Pilarska-Deltow,
  • Aneta Bąk,
  • Marta Heise,
  • Anna Latos-Bieleńska,
  • Jacek Zaremba,
  • Alicja Bartoszewska-Kubiak and
  • Olga Haus

Background: Ehlers-Danlos syndrome (EDS) is a common non-inflammatory, congenital connective tissue disorder. Classical type (cEDS) EDS is one of the more common forms, typically caused by mutations in the COL5A1 and COL5A2 genes, though causative mu...

  • Article
  • Open Access
1 Citations
2,727 Views
16 Pages

15 November 2022

In a sample of 34 countries during 1965Q2 to 2021Q3, this paper offers an empirical analysis of how household debt and oil price shocks influence economic growth in the shadow of the pandemic. We exploit the quarter lags inherent in the response of d...

  • Article
  • Open Access
8 Citations
6,112 Views
17 Pages

This research aims to study the relationship between economic growth and the increase in the tourism sector in Italy. Unlike most of the literature, we use the value added in the main economic sectors involved in tourism activity as a proxy for touri...

  • Article
  • Open Access
49 Citations
12,458 Views
32 Pages

8 February 2018

This study examines how various actors influence the transition to a renewable-energy economy. We employ a conceptual framework derived from a literature review and text-mining analysis and establish a panel data model for an empirical test using unb...

  • Article
  • Open Access
15 Citations
3,461 Views
17 Pages

The relationship between regional tourism development and air quality is complex. Although air pollution restricts tourists’ willingness to travel, the air pollution produced by tourism and its ancillary industries can also not be ignored. Usin...

  • Article
  • Open Access
9 Citations
2,488 Views
11 Pages

30 October 2021

Glechoma hederacea var. longituba (GHL) is one of many herbal plants widely used in hot herbal teas and in oriental prescriptions to treat various diseases. Although the beneficial effects of GHL may be influenced by differences in the composition of...

  • Article
  • Open Access
22 Citations
3,017 Views
15 Pages

How Do Urban Land Expansion, Land Finance, and Economic Growth Interact?

  • Ke Zhao,
  • Danling Chen,
  • Xupeng Zhang and
  • Xiaojie Zhang

Land finance has consumed a lot of China’s urban land resources while contributing to its economic growth. Urban land expansion, land finance, and economic growth have attracted significant scholarly and social attention. However, the influence...

  • Article
  • Open Access
46 Citations
2,974 Views
20 Pages

Energy and Mineral Resources Exploitation in the Delignitization Era: The Case of Greek Peripheries

  • Eleni Zafeiriou,
  • Konstantinos Spinthiropoulos,
  • Constantinos Tsanaktsidis,
  • Stavros Garefalakis,
  • Konstantinos Panitsidis,
  • Alexandros Garefalakis and
  • Garyfallos Arabatzis

28 June 2022

The efficient and sustainable exploitation of energy resources may secure a sustainable economic growth for different regions. However, the peripheries are subject to social, economic, and political constraints, with limited power over energy managem...

  • Case Report
  • Open Access
3,357 Views
9 Pages

A Very Early Diagnosis of Complete Androgen Insensitivity Syndrome Due to a Novel Variant in the AR Gene: A Neonatal Case Study

  • Rossella Ferrante,
  • Stefano Tumini,
  • Maria Alessandra Saltarelli,
  • Sara Di Rado,
  • Vincenzo Scorrano,
  • Maria Lucia Tommolini,
  • Mirco Zucchelli,
  • Federico Lauriola,
  • Gabriele Lisi and
  • Giuseppe Lauriti
  • + 4 authors

Androgen insensitivity syndrome (AIS) is one of the most common Disorders of Sexual Differentiation (DSDs). AIS is characterized by an X-linked recessive inheritance pattern associated with variants in the androgen receptor (AR) gene that affects the...

  • Article
  • Open Access
1 Citations
1,355 Views
13 Pages

Genotypic and Phenotypic Characterization of Axonal Charcot–Marie–Tooth Disease in Childhood: Identification of One Novel and Four Known Mutations

  • Rojan İpek,
  • Büşra Eser Çavdartepe,
  • Sevcan Tuğ Bozdoğan,
  • Erman Altunışık,
  • Akçahan Akalın,
  • Mahmut Yaman,
  • Alper Akın and
  • Sefer Kumandaş

30 July 2025

Background: Charcot–Marie–Tooth disease (CMT) is a genetically and phenotypically heterogeneous hereditary neuropathy. Axonal CMT type 2 (CMT2) subtypes often exhibit overlapping clinical features, which makes molecular genetic analysis e...

  • Article
  • Open Access
6 Citations
2,462 Views
11 Pages

22 December 2023

This paper examines the causal relationship between human capital and economic factors in BRICS countries using a panel vector autoregressive model and data from 1997 to 2020. The economic factors considered include foreign direct investment (FDI), i...

  • Article
  • Open Access
1 Citations
1,785 Views
16 Pages

Cosmic Whirl: Navigating the Comet Trail in DNA: H2AX Phosphorylation and the Enigma of Uncertain Significance Variants

  • Sevdican Ustun Yilmaz,
  • Nihat Bugra Agaoglu,
  • Karin Manto,
  • Meltem Muftuoglu and
  • Ugur Özbek

1 June 2024

Pathogenic variations in the BRCA2 gene have been detected with the development of next-generation sequencing (NGS)-based hereditary cancer panel testing technology. It also reveals an increasing number of variants of uncertain significance (VUSs). W...

  • Article
  • Open Access
3 Citations
3,576 Views
20 Pages

16 February 2019

Through an investigation into seven major industries in China’s stock market from 2002 to 2013, this study focuses on two main external determinants: market condition and policy change on intra-industry information diffusion. We employ both tim...

  • Article
  • Open Access
8 Citations
4,319 Views
11 Pages

Chemical, Bioactivity, and Biosynthetic Screening of Epiphytic Fungus Zasmidium pseudotsugae

  • Gisela A. González-Montiel,
  • Elizabeth N. Kaweesa,
  • Nicolas Feau,
  • Richard C. Hamelin,
  • Jeffrey K. Stone and
  • Sandra Loesgen

We report the first secondary metabolite, 8,8′-bijuglone, obtained from pure cultures of the slow growing Douglas fir- (Pseudotsuga menziesii var. menziesii) foliage-associated fungus Zasmidium pseudotsugae. The quinone was characterized using...

  • Article
  • Open Access
14 Citations
7,078 Views
16 Pages

The aim of this report is to describe results of BRCA1 and BRCA2 Next Generation Sequencing Analysis (NGS) analysis in 132 selected Italian patients with breast/ovarian cancer. A NGS pipeline with a reliable Copy Number Variation (CNV) prediction alg...

  • Article
  • Open Access
14 Citations
4,373 Views
12 Pages

Molecular Profiling of Endometrial Cancer: An Exploratory Study in Aotearoa, New Zealand

  • Claire E. Henry,
  • Khoi Phan,
  • Elena J. Orsman,
  • Diane Kenwright,
  • Michelle C. Thunders and
  • Sara K. Filoche

11 November 2021

Background: Aotearoa, New Zealand, has one of the fastest-rising rates of endometrial cancer (EC) worldwide, increasing particularly in younger Māori and Pasifika women. There is a move towards using molecular profiling to direct treatment for each E...

  • Article
  • Open Access
1 Citations
871 Views
53 Pages

6 June 2025

In the context of accelerated digitization and the transition to sustainability, this study explores the relationship between the use of cloud computing services and greenhouse gas (GHG) emissions in the IT and communications sectors at the European...

  • Brief Report
  • Open Access
4 Citations
3,433 Views
7 Pages

BRCA1/2 NGS Somatic Testing in Clinical Practice: A Short Report

  • Francesco Pepe,
  • Pasquale Pisapia,
  • Gianluca Russo,
  • Mariantonia Nacchio,
  • Pierlorenzo Pallante,
  • Elena Vigliar,
  • Carmine De Angelis,
  • Luigi Insabato,
  • Claudio Bellevicine and
  • Sabino De Placido
  • + 2 authors

28 November 2021

High-grade serous ovarian carcinoma (HGSOC) is the most common subtype of all ovarian carcinomas. HGSOC harboring BRCA1/2 germline or somatic mutations are sensitive to the poly (adenosine diphosphate-ribose) polymerase inhibitors (PARPi). Therefore,...

  • Article
  • Open Access
2,344 Views
18 Pages

Evaluation of Low-Coverage Sequencing Strategies for Whole-Genome Imputation in Pacific Abalone Haliotis discus hannai

  • Chengxia Fei,
  • Shoudu Zhang,
  • Xiangrui Chen,
  • Junyu Liu,
  • Wenzhu Peng,
  • Guofan Zhang,
  • Weiwei You and
  • Fucun Wu

Low-coverage whole-genome sequencing (lcWGS) followed by imputation is emerging as a cost-effective method for generating a substantial number of single nucleotide polymorphism (SNP) in aquatic species with highly heterozygous and complex genomes. Th...

  • Review
  • Open Access
5 Citations
3,547 Views
40 Pages

Unveiling the Spectrum of Minor Genes in Cardiomyopathies: A Narrative Review

  • Caterina Micolonghi,
  • Federica Perrone,
  • Marco Fabiani,
  • Silvia Caroselli,
  • Camilla Savio,
  • Antonio Pizzuti,
  • Aldo Germani,
  • Vincenzo Visco,
  • Simona Petrucci and
  • Speranza Rubattu
  • + 1 author

10 September 2024

Hereditary cardiomyopathies (CMPs), including arrhythmogenic cardiomyopathy (ACM), dilated cardiomyopathy (DCM), and hypertrophic cardiomyopathy (HCM), represent a group of heart disorders that significantly contribute to cardiovascular morbidity and...

  • Article
  • Open Access
5 Citations
3,829 Views
19 Pages

Targeted RNAseq Improves Clinical Diagnosis of Very Early-Onset Pediatric Immune Dysregulation

  • Kiera Berger,
  • Dalia Arafat,
  • Shanmuganathan Chandrakasan,
  • Scott B. Snapper and
  • Greg Gibson

Despite increased use of whole exome sequencing (WES) for the clinical analysis of rare disease, overall diagnostic yield for most disorders hovers around 30%. Previous studies of mRNA have succeeded in increasing diagnoses for clearly defined disord...

  • Article
  • Open Access
8 Citations
2,857 Views
22 Pages

29 July 2024

The primary objective of this study is to examine the relationships between energy consumption in agriculture from renewable and non-renewable sources and the production levels in the agricultural sector across European Union countries. Additionally,...

  • Article
  • Open Access
682 Views
25 Pages

The Sustainability Dilemma: Fiscal Rules, Institutional Quality, and Economic Outcomes in the EU

  • Oana-Ramona Lobonț,
  • Denisa-Andreea Șelaru,
  • Cristina Criste,
  • Andreea Florentina Crăciun,
  • Sorana Vătavu and
  • Petru Marin Ștefea

23 November 2025

Given that the European Union is facing complex fiscal challenges arising from recent crises, understanding the impact of fiscal rules, institutional governance, and economic performance is critical. This paper examines the effects of fiscal rules an...

  • Article
  • Open Access
8 Citations
4,908 Views
13 Pages

27 December 2021

This paper explores the impact of trade policy uncertainty (TPU) shock on China’s total factor productivity. Using economic panel data for China, OECD countries, Hong Kong SAR, Macao SAR, and Singapore from the period 2003–2019, in this p...

  • Article
  • Open Access
5 Citations
2,155 Views
11 Pages

19 November 2024

Background and Objectives: Phyllodes tumors are rare breast neoplasms with limited therapeutic options and poorly understood molecular characteristics. This study aimed to analyze genomic alterations and treatment outcomes in advanced phyllodes tumor...