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394 Results Found

  • Review
  • Open Access
5 Citations
5,597 Views
15 Pages

A Review of Advancements and Challenges in Liver Segmentation

  • Di Wei,
  • Yundan Jiang,
  • Xuhui Zhou,
  • Di Wu and
  • Xiaorong Feng

21 August 2024

Liver segmentation technologies play vital roles in clinical diagnosis, disease monitoring, and surgical planning due to the complex anatomical structure and physiological functions of the liver. This paper provides a comprehensive review of the deve...

  • Article
  • Open Access
22 Citations
6,189 Views
14 Pages

Segmentation of Liver Anatomy by Combining 3D U-Net Approaches

  • Abir Affane,
  • Adrian Kucharski,
  • Paul Chapuis,
  • Samuel Freydier,
  • Marie-Ange Lebre,
  • Antoine Vacavant and
  • Anna Fabijańska

26 May 2021

Accurate liver vessel segmentation is of crucial importance for the clinical diagnosis and treatment of many hepatic diseases. Recent state-of-the-art methods for liver vessel reconstruction mostly utilize deep learning methods, namely, the U-Net mod...

  • Review
  • Open Access
60 Citations
10,071 Views
21 Pages

12 March 2021

The segmentation of liver blood vessels is of major importance as it is essential for formulating diagnoses, planning and delivering treatments, as well as evaluating the results of clinical procedures. Different imaging techniques are available for...

  • Article
  • Open Access
127 Citations
12,440 Views
19 Pages

A Deep Learning Approach for Liver and Tumor Segmentation in CT Images Using ResUNet

  • Hameedur Rahman,
  • Tanvir Fatima Naik Bukht,
  • Azhar Imran,
  • Junaid Tariq,
  • Shanshan Tu and
  • Abdulkareeem Alzahrani

According to the most recent estimates from global cancer statistics for 2020, liver cancer is the ninth most common cancer in women. Segmenting the liver is difficult, and segmenting the tumor from the liver adds some difficulty. After a sample of l...

  • Article
  • Open Access
67 Citations
9,930 Views
15 Pages

Segmentation of Liver Tumor in CT Scan Using ResU-Net

  • Muhammad Waheed Sabir,
  • Zia Khan,
  • Naufal M. Saad,
  • Danish M. Khan,
  • Mahmoud Ahmad Al-Khasawneh,
  • Kiran Perveen,
  • Abdul Qayyum and
  • Syed Saad Azhar Ali

29 August 2022

Segmentation of images is a common task within medical image analysis and a necessary component of medical image segmentation. The segmentation of the liver and liver tumors is an important but challenging stage in screening and diagnosing liver dise...

  • Article
  • Open Access
34 Citations
4,777 Views
17 Pages

29 September 2021

The liver is an essential metabolic organ of the human body, and malignant liver tumors seriously affect and threaten human life. The segmentation algorithm for liver and liver tumors is one of the essential branches of computer-aided diagnosis. This...

  • Article
  • Open Access
53 Citations
8,334 Views
21 Pages

Fully Automatic Liver and Tumor Segmentation from CT Image Using an AIM-Unet

  • Fırat Özcan,
  • Osman Nuri Uçan,
  • Songül Karaçam and
  • Duygu Tunçman

The segmentation of the liver is a difficult process due to the changes in shape, border, and density that occur in each section in computed tomography (CT) images. In this study, the Adding Inception Module-Unet (AIM-Unet) model, which is a hybridiz...

  • Article
  • Open Access
15 Citations
4,619 Views
20 Pages

Deep Learning Framework for Liver Segmentation from T1-Weighted MRI Images

  • Md. Sakib Abrar Hossain,
  • Sidra Gul,
  • Muhammad E. H. Chowdhury,
  • Muhammad Salman Khan,
  • Md. Shaheenur Islam Sumon,
  • Enamul Haque Bhuiyan,
  • Amith Khandakar,
  • Maqsud Hossain,
  • Abdus Sadique and
  • Abdulrahman Alqahtani
  • + 2 authors

1 November 2023

The human liver exhibits variable characteristics and anatomical information, which is often ambiguous in radiological images. Machine learning can be of great assistance in automatically segmenting the liver in radiological images, which can be furt...

  • Article
  • Open Access
20 Citations
8,563 Views
16 Pages

29 May 2020

Liver and liver tumor segmentation based on abdomen computed tomography (CT) images is an essential step in computer-assisted clinical interventions. However, liver and tumor segmentation remains the difficult issue in the medical image processing fi...

  • Article
  • Open Access
54 Citations
6,829 Views
19 Pages

APESTNet with Mask R-CNN for Liver Tumor Segmentation and Classification

  • Prabhu Kavin Balasubramanian,
  • Wen-Cheng Lai,
  • Gan Hong Seng,
  • Kavitha C and
  • Jeeva Selvaraj

4 January 2023

Diagnosis and treatment of hepatocellular carcinoma or metastases rely heavily on accurate segmentation and classification of liver tumours. However, due to the liver tumor’s hazy borders and wide range of possible shapes, sizes, and positions,...

  • Article
  • Open Access
2,318 Views
13 Pages

14 December 2022

Liver segmentation from abdominal computed tomography (CT) images is a primary step in the diagnosis and treatment of liver cancer, but previous liver segmentation methods have the problems of excessive demand for prior knowledge, under- and oversegm...

  • Article
  • Open Access
45 Citations
4,657 Views
16 Pages

23 March 2022

Segmenting medical images is a necessary prerequisite for disease diagnosis and treatment planning. Among various medical image segmentation tasks, U-Net-based variants have been widely used in liver tumor segmentation tasks. In view of the highly va...

  • Article
  • Open Access
8 Citations
2,347 Views
21 Pages

18 September 2023

In recent years, U-Net and its extended variants have made remarkable progress in the realm of liver and liver tumor segmentation. However, the limitations of single-path convolutional operations have hindered the full exploitation of valuable featur...

  • Article
  • Open Access
9 Citations
2,759 Views
15 Pages

Multi-Resolution Image Segmentation Based on a Cascaded U-ADenseNet for the Liver and Tumors

  • Yan Zhu,
  • Aihong Yu,
  • Huan Rong,
  • Dongqing Wang,
  • Yuqing Song,
  • Zhe Liu and
  • Victor S. Sheng

19 October 2021

The liver is an irreplaceable organ in the human body, maintaining life activities and metabolism. Malignant tumors of the liver have a high mortality rate at present. Computer-aided segmentation of the liver and tumors has significant effects on cli...

  • Article
  • Open Access
3 Citations
2,364 Views
20 Pages

A Comparative Study of Decoders for Liver and Tumor Segmentation Using a Self-ONN-Based Cascaded Framework

  • Sidra Gul,
  • Muhammad Salman Khan,
  • Md Sakib Abrar Hossain,
  • Muhammad E. H. Chowdhury and
  • Md. Shaheenur Islam Sumon

8 December 2024

Background/Objectives: Accurate liver and tumor detection and segmentation are crucial in diagnosis of early-stage liver malignancies. As opposed to manual interpretation, which is a difficult and time-consuming process, accurate tumor detection usin...

  • Article
  • Open Access
22 Citations
6,913 Views
21 Pages

Automatic Liver Tumor Segmentation from CT Images Using Graph Convolutional Network

  • Maryam Khoshkhabar,
  • Saeed Meshgini,
  • Reza Afrouzian and
  • Sebelan Danishvar

1 September 2023

Segmenting the liver and liver tumors in computed tomography (CT) images is an important step toward quantifiable biomarkers for a computer-aided decision-making system and precise medical diagnosis. Radiologists and specialized physicians use CT ima...

  • Article
  • Open Access
2,447 Views
12 Pages

Adaptive Evolutionary Optimization of Deep Learning Architectures for Focused Liver Ultrasound Image Segmentation

  • Ali Zifan,
  • Katelyn Zhao,
  • Madilyn Lee,
  • Zihan Peng,
  • Laura J. Roney,
  • Sarayu Pai,
  • Jake T. Weeks,
  • Michael S. Middleton,
  • Ahmed El Kaffas and
  • Claude B. Sirlin

Background: Liver ultrasound segmentation is challenging due to low image quality and variability. While deep learning (DL) models have been widely applied for medical segmentation, generic pre-configured models may not meet the specific requirements...

  • Article
  • Open Access
2 Citations
1,540 Views
18 Pages

14 March 2025

Accurate segmentation of the liver and liver tumors is crucial for clinical diagnosis and treatment. However, the task poses significant challenges due to the complex morphology of tumors, indistinct features of small targets, and the similarity in g...

  • Review
  • Open Access
7 Citations
3,264 Views
19 Pages

Algorithms for Liver Segmentation in Computed Tomography Scans: A Historical Perspective

  • Stephanie Batista Niño,
  • Jorge Bernardino and
  • Inês Domingues

8 March 2024

Oncology has emerged as a crucial field of study in the domain of medicine. Computed tomography has gained widespread adoption as a radiological modality for the identification and characterisation of pathologies, particularly in oncology, enabling p...

  • Article
  • Open Access
1 Citations
1,288 Views
35 Pages

Liver Semantic Segmentation Method Based on Multi-Channel Feature Extraction and Cross Fusion

  • Chenghao Zhang,
  • Lingfei Wang,
  • Chunyu Zhang,
  • Yu Zhang,
  • Peng Wang and
  • Jin Li

Semantic segmentation plays a critical role in medical image analysis, offering indispensable information for the diagnosis and treatment planning of liver diseases. However, due to the complex anatomical structure of the liver and significant inter-...

  • Article
  • Open Access
9 Citations
3,159 Views
19 Pages

Deep Learning Algorithms in the Automatic Segmentation of Liver Lesions in Ultrasound Investigations

  • Mădălin Mămuleanu,
  • Cristiana Marinela Urhuț,
  • Larisa Daniela Săndulescu,
  • Constantin Kamal,
  • Ana-Maria Pătrașcu,
  • Alin Gabriel Ionescu,
  • Mircea-Sebastian Șerbănescu and
  • Costin Teodor Streba

14 November 2022

Background: The ultrasound is one of the most used medical imaging investigations worldwide. It is non-invasive and effective in assessing liver tumors or other types of parenchymal changes. Methods: The aim of the study was to build a deep learning...

  • Article
  • Open Access
8 Citations
2,056 Views
36 Pages

Explainable and Robust Deep Learning for Liver Segmentation Through U-Net Network

  • Maria Chiara Brunese,
  • Aldo Rocca,
  • Antonella Santone,
  • Mario Cesarelli,
  • Luca Brunese and
  • Francesco Mercaldo

Background/Objectives: Clinical imaging techniques, such as magnetic resonance imaging and computed tomography, play a vital role in supporting clinicians by aiding disease diagnosis and facilitating the planning of appropriate interventions. This is...

  • Article
  • Open Access
3 Citations
2,347 Views
18 Pages

G-UNETR++: A Gradient-Enhanced Network for Accurate and Robust Liver Segmentation from Computed Tomography Images

  • Seungyoo Lee,
  • Kyujin Han,
  • Hangyeul Shin,
  • Harin Park,
  • Seunghyon Kim,
  • Jeonghun Kim,
  • Xiaopeng Yang,
  • Jae Do Yang,
  • Hee Chul Yu and
  • Heecheon You

16 January 2025

Accurate liver segmentation from computed tomography (CT) scans is essential for liver cancer diagnosis and liver surgery planning. Convolutional neural network (CNN)-based models have limited segmentation performance due to their localized receptive...

  • Article
  • Open Access
7 Citations
4,206 Views
21 Pages

13 October 2022

This research aimed to investigate the relationship and the correlation between abdomen fat accumulation and the level of diffused fat in the human liver using computerized methods. Computed tomography data sets of 125 subjects were employed in this...

  • Feature Paper
  • Article
  • Open Access
2 Citations
3,346 Views
18 Pages

14 October 2022

This paper introduces an approach for 3D organ segmentation that generalizes in multiple ways the Chan-Vese level set method. Chan-Vese is a segmentation method that simultaneously evolves a level set while fitting locally constant intensity models f...

  • Article
  • Open Access
3 Citations
3,792 Views
10 Pages

9 February 2022

Purpose: To develop and integrate interactive features with automatic methods for accurate liver cyst segmentation in patients with autosomal dominant polycystic kidney and liver disease (ADPKD). Methods: SmartClick and antiSmartClick were developed...

  • Article
  • Open Access
11 Citations
4,059 Views
20 Pages

26 December 2022

Liver segmentation is a prerequisite for various hepatic interventions and is a time-consuming manual task performed by radiology experts. Recently, various computationally expensive deep learning architectures tackled this aspect without considering...

  • Article
  • Open Access
3 Citations
3,546 Views
12 Pages

A Coarse-to-Fine Fusion Network for Small Liver Tumor Detection and Segmentation: A Real-World Study

  • Shu Wu,
  • Hang Yu,
  • Cuiping Li,
  • Rencheng Zheng,
  • Xueqin Xia,
  • Chengyan Wang and
  • He Wang

Liver tumor semantic segmentation is a crucial task in medical image analysis that requires multiple MRI modalities. This paper proposes a novel coarse-to-fine fusion segmentation approach to detect and segment small liver tumors of various sizes. To...

  • Article
  • Open Access
2 Citations
1,244 Views
18 Pages

9 July 2025

The deep learning-based analysis of liver CT images is expected to provide assistance for clinicians in the diagnostic decision-making process. However, the accuracy of existing methods still falls short of clinical requirements and needs to be furth...

  • Article
  • Open Access
7 Citations
6,354 Views
20 Pages

The liver is a vital organ in the human body, and CT images can intuitively display its morphology. Physicians rely on liver CT images to observe its anatomical structure and areas of pathology, providing evidence for clinical diagnosis and treatment...

  • Article
  • Open Access
9 Citations
3,727 Views
28 Pages

Given its essential role in body functions, liver cancer is the third most common cause of death from cancer, despite being the sixth most common type of cancer worldwide. Following advancements in medicine and image processing, medical image segment...

  • Article
  • Open Access
935 Views
13 Pages

Liver tumors negatively affect vital functions such as digestion and nutrient storage, significantly reducing patients’ quality of life. Therefore, early detection and accurate treatment planning are of great importance. This study aims to supp...

  • Article
  • Open Access
859 Views
30 Pages

Private Data Incrementalization: Data-Centric Model Development for Clinical Liver Segmentation

  • Stephanie Batista,
  • Miguel Couceiro,
  • Ricardo Filipe,
  • Paulo Rachinhas,
  • Jorge Isidoro and
  • Inês Domingues

Machine Learning models, more specifically Artificial Neural Networks, are transforming medical imaging by enabling precise liver segmentation, a crucial task for diagnosing and treating liver diseases. However, these models often face challenges in...

  • Article
  • Open Access
26 Citations
3,165 Views
23 Pages

En–DeNet Based Segmentation and Gradational Modular Network Classification for Liver Cancer Diagnosis

  • Suganeshwari G,
  • Jothi Prabha Appadurai,
  • Balasubramanian Prabhu Kavin,
  • Kavitha C and
  • Wen-Cheng Lai

Liver cancer ranks as the sixth most prevalent cancer among all cancers globally. Computed tomography (CT) scanning is a non-invasive analytic imaging sensory system that provides greater insight into human structures than traditional X-rays, which a...

  • Article
  • Open Access
4 Citations
2,736 Views
22 Pages

A Boundary-Enhanced Liver Segmentation Network for Multi-Phase CT Images with Unsupervised Domain Adaptation

  • Swathi Ananda,
  • Rahul Kumar Jain,
  • Yinhao Li,
  • Yutaro Iwamoto,
  • Xian-Hua Han,
  • Shuzo Kanasaki,
  • Hongjie Hu and
  • Yen-Wei Chen

Multi-phase computed tomography (CT) images have gained significant popularity in the diagnosis of hepatic disease. There are several challenges in the liver segmentation of multi-phase CT images. (1) Annotation: due to the distinct contrast enhancem...

  • Letter
  • Open Access
10 Citations
3,237 Views
12 Pages

Semantic Segmentation of Intralobular and Extralobular Tissue from Liver Scaffold H&E Images

  • Miroslav Jirik,
  • Ivan Gruber,
  • Vladimira Moulisova,
  • Claudia Schindler,
  • Lenka Cervenkova,
  • Richard Palek,
  • Jachym Rosendorf,
  • Janine Arlt,
  • Lukas Bolek and
  • Vaclav Liska
  • + 2 authors

10 December 2020

Decellularized tissue is an important source for biological tissue engineering. Evaluation of the quality of decellularized tissue is performed using scanned images of hematoxylin-eosin stained (H&E) tissue sections and is usually dependent on th...

  • Article
  • Open Access
754 Views
17 Pages

CT-Based Radiomic Models in Biopsy-Proven Liver Fibrosis Staging: Direct Comparison of Segmentation Types and Organ Inclusion

  • Andreea Mihaela Morariu-Barb,
  • Tudor Drugan,
  • Mihai Adrian Socaciu,
  • Horia Stefanescu,
  • Andrei Demirel Morariu and
  • Monica Lupsor-Platon

23 October 2025

Background and Objectives: Liver fibrosis is the key prognostic factor in patients with chronic liver diseases (CLD). Computed tomography (CT) is widely used in clinical practice, but it has limited value in assessing liver fibrosis in precirrhotic s...

  • Article
  • Open Access
2 Citations
1,825 Views
19 Pages

Abdominal CT images are important clues for diagnosing liver cancer lesions. However, liver cancer presents challenges such as significant differences in tumor size, shape, and location, which can affect segmentation accuracy. To address these challe...

  • Article
  • Open Access
1,507 Views
38 Pages

Liver Tumor Segmentation Based on Multi-Scale Deformable Feature Fusion and Global Context Awareness

  • Chenghao Zhang,
  • Lingfei Wang,
  • Chunyu Zhang,
  • Yu Zhang,
  • Jin Li and
  • Peng Wang

1 September 2025

The highly heterogeneous and irregular morphology of liver tumors presents considerable challenges for automated segmentation. To better capture complex tumor structures, this study proposes a liver tumor segmentation framework based on multi-scale d...

  • Article
  • Open Access
8 Citations
3,448 Views
19 Pages

26 August 2024

The early detection of liver fibrosis is of significant importance. Deep learning analysis of ultrasound backscattered radiofrequency (RF) signals is emerging for tissue characterization as the RF signals carry abundant information related to tissue...

  • Article
  • Open Access
2 Citations
2,592 Views
22 Pages

4 April 2025

Automatic liver and tumor segmentation in contrast-enhanced magnetic resonance imaging (CE-MRI) images are of great value in clinical practice as they can reduce surgeons’ workload and increase the probability of success in surgery. However, th...

  • Article
  • Open Access
1 Citations
1,622 Views
17 Pages

Magnetic Resonance Imaging Liver Segmentation Protocol Enables More Consistent and Robust Annotations, Paving the Way for Advanced Computer-Assisted Analysis

  • Patrick Jeltsch,
  • Killian Monnin,
  • Mario Jreige,
  • Lucia Fernandes-Mendes,
  • Raphaël Girardet,
  • Clarisse Dromain,
  • Jonas Richiardi and
  • Naik Vietti-Violi

11 December 2024

Background/Objectives: Recent advancements in artificial intelligence (AI) have spurred interest in developing computer-assisted analysis for imaging examinations. However, the lack of high-quality datasets remains a significant bottleneck. Labeling...

  • Article
  • Open Access
5 Citations
1,834 Views
24 Pages

21 February 2025

Liver cancer is a major global health challenge, significantly contributing to mortality rates. The accurate segmentation of liver and tumors from clinical CT images plays a crucial role in selecting therapeutic strategies for liver disease and treat...

  • Article
  • Open Access
8 Citations
2,532 Views
19 Pages

9 September 2024

Liver cancer is one of the malignancies with high mortality rates worldwide, and its timely detection and accurate diagnosis are crucial for improving patient prognosis. To address the limitations of traditional image segmentation techniques and the...

  • Article
  • Open Access
5 Citations
2,597 Views
15 Pages

Application of A U-Net for Map-like Segmentation and Classification of Discontinuous Fibrosis Distribution in Gd-EOB-DTPA-Enhanced Liver MRI

  • Quirin David Strotzer,
  • Hinrich Winther,
  • Kirsten Utpatel,
  • Alexander Scheiter,
  • Claudia Fellner,
  • Michael Christian Doppler,
  • Kristina Imeen Ringe,
  • Florian Raab,
  • Michael Haimerl and
  • Niklas Verloh
  • + 2 authors

We aimed to evaluate whether U-shaped convolutional neuronal networks can be used to segment liver parenchyma and indicate the degree of liver fibrosis/cirrhosis at the voxel level using contrast-enhanced magnetic resonance imaging. This retrospectiv...

  • Article
  • Open Access
7 Citations
2,627 Views
16 Pages

Enhancing Surgical Guidance: Deep Learning-Based Liver Vessel Segmentation in Real-Time Ultrasound Video Frames

  • Muhammad Awais,
  • Mais Al Taie,
  • Caleb S. O’Connor,
  • Austin H. Castelo,
  • Belkacem Acidi,
  • Hop S. Tran Cao and
  • Kristy K. Brock

30 October 2024

Background/Objectives: In the field of surgical medicine, the planning and execution of liver resection procedures present formidable challenges, primarily attributable to the intricate and highly individualized nature of liver vascular anatomy. In t...

  • Article
  • Open Access
4 Citations
2,105 Views
15 Pages

Background: Liver cancer has a high mortality rate worldwide, and clinicians segment liver vessels in CT images before surgical procedures. However, liver vessels have a complex structure, and the segmentation process is conducted manually, so it is...

  • Article
  • Open Access
12 Citations
3,832 Views
17 Pages

Multi-Scale Attention Convolutional Network for Masson Stained Bile Duct Segmentation from Liver Pathology Images

  • Chun-Han Su,
  • Pau-Choo Chung,
  • Sheng-Fung Lin,
  • Hung-Wen Tsai,
  • Tsung-Lung Yang and
  • Yu-Chieh Su

31 March 2022

In clinical practice, the Ishak Score system would be adopted to perform the evaluation of the grading and staging of hepatitis according to whether portal areas have fibrous expansion, bridging with other portal areas, or bridging with central veins...

  • Article
  • Open Access
2,659 Views
23 Pages

High-Precision, Automatic, and Fast Segmentation Method of Hepatic Vessels and Liver Tumors from CT Images Using a Fusion Decision-Based Stacking Deep Learning Model

  • Mamoun Qjidaa,
  • Anass Benfares,
  • Mohammed Amine El Azami El Hassani,
  • Amine Benkabbou,
  • Amine Souadka,
  • Anass Majbar,
  • Zakaria El Moatassim,
  • Maroua Oumlaz,
  • Oumayma Lahnaoui and
  • Abdeljabbar Cherkaoui
  • + 1 author

Background: To propose an automatic liver and hepatic vessel segmentation solution based on a stacking model and decision fusion. This model combines the decisions of multiple models to achieve increased accuracy. It exhibits improved robustness due...

  • Article
  • Open Access
19 Citations
5,992 Views
19 Pages

30 April 2021

Image segmentation plays an important role in the field of image processing, helping to understand images and recognize objects. However, most existing methods are often unable to effectively explore the spatial information in 3D image segmentation,...

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