- Article
Replacing a Palatable High-Fat Diet with a Low-Fat Alternative Heightens κ-Opioid Receptor Control over Nucleus Accumbens Dopamine
- Conner W. Wallace,
- Nari S. Beatty,
- Sarah A. Hutcherson,
- Heather A. Emmons,
- Madison C. Loudermilt and
- Steve C. Fordahl
Diet-induced obesity reduces dopaminergic neurotransmission in the nucleus accumbens (NAc), and stressful weight loss interventions could promote cravings for palatable foods high in fat and sugar that stimulate dopamine. Activation of κ-opioid recep...