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1,886 Results Found

  • Article
  • Open Access
1 Citations
2,989 Views
12 Pages

4 December 2023

This research aimed to assess the relationship between contrast-enhanced (CE) magnetic resonance fingerprinting (MRF) values and dynamic contrast-enhanced (DCE) MRI parameters including (Ktrans, Kep, Ve, and iAUC). To evaluate the correlation between...

  • Article
  • Open Access
9 Citations
2,767 Views
10 Pages

The Frequency and Causes of Not-Detected Breast Malignancy in Dynamic Contrast-Enhanced MRI

  • Donghun Song,
  • Bong Joo Kang,
  • Sung Hun Kim,
  • Jeongmin Lee and
  • Ga Eun Park

24 October 2022

Breast MR is the most sensitive imaging modality, but there are cases of malignant tumors that are not detected in MR. This study evaluated the frequency and main causes of malignant breast lesions not detected in dynamic contrast-enhanced (DCE) MR....

  • Review
  • Open Access
2 Citations
4,169 Views
14 Pages

Ultrasound in Adhesive Capsulitis: A Narrative Exploration from Static Imaging to Contrast-Enhanced, Dynamic and Sonoelastographic Insights

  • Wei-Ting Wu,
  • Ke-Vin Chang,
  • Kamal Mezian,
  • Vincenzo Ricci,
  • Consuelo B. Gonzalez-Suarez and
  • Levent Özçakar

Adhesive capsulitis is a painful and progressive condition marked by significant limitations in shoulder mobility, particularly affecting external rotation. Although magnetic resonance imaging is regarded as the reference standard for assessing intra...

  • Article
  • Open Access
6 Citations
2,771 Views
15 Pages

Application of Dynamic Contrast-Enhanced Ultrasound in Evaluation the Activity of Crohn’s Disease

  • Ying Wang,
  • Li Wei,
  • Wen-Song Ge,
  • You-Rong Duan,
  • Wen-Jun Ding,
  • Xiu-Yun Lu,
  • Yun-Lin Huang,
  • Sheng Chen,
  • Yi Dong and
  • Peng Du

Background and Objective: The dynamic assessment of disease activity during the follow-up of patients with Crohn’s disease (CD) remains a significant challenge. In this study, we aimed to identify the role of dynamic contrast-enhanced ultrasoun...

  • Review
  • Open Access
3 Citations
2,542 Views
14 Pages

Dynamic Contrast-Enhanced Ultrasound in the Prediction of Advanced Hepatocellular Carcinoma Response to Systemic and Locoregional Therapies

  • Lucia Cerrito,
  • Maria Elena Ainora,
  • Giuseppe Cuccia,
  • Linda Galasso,
  • Irene Mignini,
  • Giorgio Esposto,
  • Matteo Garcovich,
  • Laura Riccardi,
  • Antonio Gasbarrini and
  • Maria Assunta Zocco

27 January 2024

Hepatocellular carcinoma (HCC) is the most frequent primary liver cancer and the sixth most common malignant tumor in the world, with an incidence of 2–8% per year in patients with hepatic cirrhosis or chronic hepatitis. Despite surveillance sc...

  • Article
  • Open Access
1 Citations
2,977 Views
15 Pages

24 March 2023

This paper investigates the effect of anisotropic resolution on the image textural features of pharmacokinetic (PK) parameters of a murine glioma model using dynamic contrast-enhanced (DCE) MR images acquired with an isotropic resolution at 7T with p...

  • Article
  • Open Access
13 Citations
8,964 Views
9 Pages

Dynamic Contrast-Enhanced Ultrasound of Colorectal Liver Metastases as an Imaging Modality for Early Response Prediction to Chemotherapy

  • Marie Benzon Mogensen,
  • Martin Lundsgaard Hansen,
  • Birthe Merete Henriksen,
  • Thomas Axelsen,
  • Ben Vainer,
  • Kell Osterlind and
  • Michael Bachmann Nielsen

Our aim was to investigate whether dynamic contrast-enhanced ultrasound (DCE-US) can detect early changes in perfusion of colorectal liver metastases after initiation of chemotherapy. Newly diagnosed patients with colorectal cancer with liver metasta...

  • Systematic Review
  • Open Access
10 Citations
4,183 Views
8 Pages

(1) Background: Blood brain barrier (BBB) disruption following traumatic brain injury (TBI) results in a secondary injury by facilitating the entry of neurotoxins to the brain parenchyma without filtration. In the current paper, we aimed to review pr...

  • Article
  • Open Access
8 Citations
2,259 Views
12 Pages

Early Assessment of Chemoradiotherapy Response for Locally Advanced Pancreatic Ductal Adenocarcinoma by Dynamic Contrast-Enhanced Ultrasound

  • Xiu-Yun Lu,
  • Xi Guo,
  • Qi Zhang,
  • Yi-Jie Qiu,
  • Dan Zuo,
  • Sheng Chen,
  • Xiao-Fan Tian,
  • Yu-Hong Zhou,
  • Yi Dong and
  • Wen-Ping Wang

2 November 2022

Objective: To evaluate the value of dynamic contrast-enhanced ultrasound (DCE-US) and quantitative parameters in early prediction of tumor response to chemoradiotherapy (CRT) in patients with locally advanced pancreatic ductal adenocarcinoma (LAPC)....

  • Review
  • Open Access
6 Citations
6,717 Views
17 Pages

Assessing Tumor Response to Treatment in Patients with Lung Cancer Using Dynamic Contrast-Enhanced CT

  • Louise S. Strauch,
  • Rie Ø. Eriksen,
  • Michael Sandgaard,
  • Thomas S. Kristensen,
  • Michael B. Nielsen and
  • Carsten A. Lauridsen

The aim of this study was to provide an overview of the literature available on dynamic contrast-enhanced computed tomography (DCE-CT) as a tool to evaluate treatment response in patients with lung cancer. This systematic review was compiled accordin...

  • Article
  • Open Access
10 Citations
3,189 Views
15 Pages

Prediction of Pathological Grades of Pancreatic Neuroendocrine Tumors Based on Dynamic Contrast-Enhanced Ultrasound Quantitative Analysis

  • Dao-Hui Yang,
  • Juan Cheng,
  • Xiao-Fan Tian,
  • Qi Zhang,
  • Ling-Yun Yu,
  • Yi-Jie Qiu,
  • Xiu-Yun Lu,
  • Wen-Hui Lou,
  • Yi Dong and
  • Wen-Ping Wang

Objective: To investigate whether the dynamic contrast-enhanced ultrasound (DCE-US) analysis and quantitative parameters could be helpful for predicting histopathologic grades of pancreatic neuroendocrine tumors (pNETs). Methods: This retrospective s...

  • Article
  • Open Access
559 Views
16 Pages

Performance of Radiologists in Characterizing and Diagnosing Hepatic Lesions Using Dynamic Contrast-Enhanced CT With and Without Artificial Intelligence

  • Daiki Nishigaki,
  • Atsushi Nakamoto,
  • Takahiro Tsuboyama,
  • Hiromitsu Onishi,
  • Yuki Suzuki,
  • Tomohiro Wataya,
  • Kosuke Kita,
  • Junya Sato,
  • Miyuki Tomiyama and
  • Noriyuki Tomiyama
  • + 3 authors

Background: To investigate the performance of radiologists in characterizing and diagnosing hepatic lesions with and without the assistance of deep learning-based artificial intelligence (AI). Methods: This retrospective study included 83 nodules/mas...

  • Article
  • Open Access
3 Citations
2,711 Views
14 Pages

Glioma Type Prediction with Dynamic Contrast-Enhanced MR Imaging and Diffusion Kurtosis Imaging—A Standardized Multicenter Study

  • Leonie Zerweck,
  • Till-Karsten Hauser,
  • Uwe Klose,
  • Tong Han,
  • Thomas Nägele,
  • Mi Shen,
  • Georg Gohla,
  • Arne Estler,
  • Chuanmiao Xie and
  • Vivien Richter
  • + 5 authors

25 July 2024

The aim was to explore the performance of dynamic contrast-enhanced (DCE) MRI and diffusion kurtosis imaging (DKI) in differentiating the molecular subtypes of adult-type gliomas. A multicenter MRI study with standardized imaging protocols, including...

  • Review
  • Open Access
3,682 Views
20 Pages

Quantitative dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) is emerging as a valuable tool for assessing tumor and parenchymal perfusion in the liver, playing a developing role in locoregional therapies (LRTs) for hepatocellular carci...

  • Communication
  • Open Access
2 Citations
1,751 Views
9 Pages

Delay of Aortic Arterial Input Function Time Improves Detection of Malignant Vertebral Body Lesions on Dynamic Contrast-Enhanced MRI Perfusion

  • Felipe Camelo,
  • Kyung K. Peck,
  • Atin Saha,
  • Julio Arevalo-Perez,
  • John K. Lyo,
  • Jamie Tisnado,
  • Eric Lis,
  • Sasan Karimi and
  • Andrei I. Holodny

18 April 2023

Dynamic contrast-enhanced MRI (DCE) is an emerging modality in the study of vertebral body malignancies. DCE-MRI analysis relies on a pharmacokinetic model, which assumes that contrast uptake is simultaneous in the feeding of arteries and tissues of...

  • Article
  • Open Access
151 Views
16 Pages

Differential Diagnosis of Oral Salivary Gland Carcinoma and Squamous Cell Carcinoma Using Quantitative Dynamic Contrast-Enhanced MRI

  • Kunjie Zeng,
  • Yanqin Zeng,
  • Xinyin Chen,
  • Siya Shi,
  • Guoxiong Lu,
  • Yusong Jiang,
  • Xing Wu,
  • Lingjie Yang,
  • Zhaoqi Lai and
  • Yun Su
  • + 1 author

20 January 2026

Background/Objectives: Preoperative differentiation between oral squamous cell carcinoma (SCC) and minor salivary gland carcinoma (SGC) remains clinically challenging due to overlapping imaging characteristics. This study aimed to develop a diagnosti...

  • Article
  • Open Access
11 Citations
5,836 Views
12 Pages

19 March 2021

We aimed to retrospectively compare the perfusion parameters measured from dynamic contrast-enhanced (DCE) magnetic resonance imaging (MRI) of prostate benign lesions and malignant lesions to determine the relationship between perfusion parameters. D...

  • Article
  • Open Access
4 Citations
2,610 Views
12 Pages

Dynamic Contrast-Enhanced Magnetic Resonance Imaging for Measuring Perfusion in Pancreatic Ductal Adenocarcinoma and Different Tumor Grade: A Preliminary Single Center Study

  • Inga Zaborienė,
  • Vestina Strakšytė,
  • Povilas Ignatavičius,
  • Giedrius Barauskas,
  • Rūta Dambrauskienė and
  • Kristina Žvinienė

Background: Dynamic contrast-enhanced magnetic resonance imaging is a noninvasive imaging modality that can supply information regarding the tumor anatomy and physiology. The aim of the study was to analyze DCE-MRI perfusion parameters in normal panc...

  • Article
  • Open Access
3 Citations
1,833 Views
17 Pages

Preoperative Adult-Type Diffuse Glioma Subtype Prediction with Dynamic Contrast-Enhanced MR Imaging and Diffusion Weighted Imaging in Tumor Cores and Peritumoral Tissue—A Standardized Multicenter Study

  • Leonie Zerweck,
  • Uwe Klose,
  • Urs Würtemberger,
  • Vivien Richter,
  • Thomas Nägele,
  • Georg Gohla,
  • Kathrin Grundmann-Hauser,
  • Arne Estler,
  • Christer Ruff and
  • Till-Karsten Hauser
  • + 2 authors

21 February 2025

Background/Objectives: The non-invasive identification of glioma subtypes is useful for initial diagnosis, treatment planning, and follow-up. The aim of this study was to evaluate the performance of diffusion kurtosis imaging (DKI) and dynamic contra...

  • Article
  • Open Access
23 Citations
2,059 Views
10 Pages

Computational Modeling of Interstitial Fluid Pressure and Velocity in Head and Neck Cancer Based on Dynamic Contrast-Enhanced Magnetic Resonance Imaging: Feasibility Analysis

  • Eve LoCastro,
  • Ramesh Paudyal,
  • Yousef Mazaheri,
  • Vaios Hatzoglou,
  • Jung Hun Oh,
  • Yonggang Lu,
  • Amaresha Shridhar Konar,
  • Kira vom Eigen,
  • Alan Ho and
  • Amita Shukla-Dave
  • + 3 authors

1 June 2020

We developed and tested the feasibility of computational fluid modeling (CFM) based on dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) for quantitative estimation of interstitial fluid pressure (IFP) and velocity (IFV) in patients with...

  • Article
  • Open Access
14 Citations
1,778 Views
11 Pages

Diffusion-Weighted and Dynamic Contrast-Enhanced MRI Derived Imaging Metrics for Stereotactic Body Radiotherapy of Pancreatic Ductal Adenocarcinoma: Preliminary Findings

  • Richard Kinh Do,
  • Marsha Reyngold,
  • Ramesh Paudyal,
  • Jung Hun Oh,
  • Amaresha Shridhar Konar,
  • Eve LoCastro,
  • Karyn A. Goodman and
  • Amita Shukla-Dave

1 June 2020

We aimed to assess longitudinal changes in quantitative imaging metric values obtained from diffusion-weighted (DW-) and dynamic contrast-enhanced magnetic resonance imaging (DCE)-MRI at pre-treatment (TX[0]), immediately after the first fraction of...

  • Feature Paper
  • Article
  • Open Access
5 Citations
3,282 Views
11 Pages

31 October 2022

The aim of this study was to explore whether intravoxel incoherent motion (IVIM) combined with a dynamic contrast–enhanced magnetic resonance imaging (DCE–MRI) quantitative model can improve the ability to distinguish between benign and m...

  • Article
  • Open Access
8 Citations
5,622 Views
15 Pages

Objective: The assessment of the usefulness of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) when qualifying patients with uterine fibroids (UFs) for magnetic resonance-guided high-intensity ultrasound (MR-HIFU). Material and methods...

  • Article
  • Open Access
1,154 Views
17 Pages

22 October 2025

Background/Objectives: Cerebral blood flow (CBF) and cerebral blood volume (CBV) are critical perfusion metrics in diagnosing ischemic stroke. Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) enables the evaluation of these cerebral per...

  • Article
  • Open Access
1,147 Views
19 Pages

Background: Previous studies have suggested that electromagnetic pulse (EMP) can induce openings in the blood–brain barrier (BBB). However, the temporal variation and spatial distribution of BBB permeability after EMP radiation are difficult to...

  • Article
  • Open Access
4 Citations
2,921 Views
12 Pages

Relative Wash-In Rate in Dynamic Contrast-Enhanced Magnetic Resonance Imaging as a New Prognostic Biomarker for Event-Free Survival in 82 Patients with Osteosarcoma: A Multicenter Study

  • Gijsbert M. Kalisvaart,
  • Richard E. Evenhuis,
  • Willem Grootjans,
  • Thomas Van Den Berghe,
  • Martijn Callens,
  • Judith V. M. G. Bovée,
  • David Creytens,
  • Hans Gelderblom,
  • Frank M. Speetjens and
  • Johan L. Bloem
  • + 5 authors

21 May 2024

Background: The decreased perfusion of osteosarcoma in dynamic contrast-enhanced (DCE) MRI, reflecting a good histological response to neoadjuvant chemotherapy, has been described. Purpose: In this study, we aim to explore the potential of the relati...

  • Article
  • Open Access
4,228 Views
14 Pages

Dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) can be used to examine the distribution of an intravenous contrast agent within the brain. Computational methods have been devised to analyse the contrast uptake/washout over time as refl...

  • Article
  • Open Access
7 Citations
3,512 Views
12 Pages

20 February 2023

Background: To evaluate the association between perfusion parameters derived from dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with prognostic factors in primary rectal cancer patients. Methods: A sample of 51 patients with patholog...

  • Article
  • Open Access
4 Citations
4,141 Views
17 Pages

Dynamic Contrast-Enhanced Magnetic Resonance Imaging for the Prediction of Monoclonal Antibody Tumor Disposition

  • Brandon M. Bordeau,
  • Joseph Ryan Polli,
  • Ferdinand Schweser,
  • Hans Peter Grimm,
  • Wolfgang F. Richter and
  • Joseph P. Balthasar

The prediction of monoclonal antibody (mAb) disposition within solid tumors for individual patients is difficult due to inter-patient variability in tumor physiology. Improved a priori prediction of mAb pharmacokinetics in tumors may facilitate the d...

  • Article
  • Open Access
4 Citations
3,453 Views
16 Pages

24 August 2022

Application of quantitative dynamic contrast-enhanced (DCE) MRI in mouse models of abdominal cancer is challenging due to the effects of RF inhomogeneity, image corruption from rapid respiratory motion and the need for high spatial and temporal resol...

  • Article
  • Open Access
5 Citations
2,890 Views
13 Pages

Feasibility Study on Using Dynamic Contrast Enhanced MRI to Assess the Effect of Tyrosine Kinase Inhibitor Therapy within the STAR Trial of Metastatic Renal Cell Cancer

  • Jim Zhong,
  • Ebrahim Palkhi,
  • David L. Buckley,
  • Fiona J. Collinson,
  • Christy Ralph,
  • Satinder Jagdev,
  • Naveen S. Vasudev,
  • Jayne Swain,
  • Janet E. Brown and
  • Tze Min Wah

Objective: To identify dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) parameters predictive of early disease progression in patients with metastatic renal cell cancer (mRCC) treated with anti-angiogenic tyrosine kinase inhibitors (TKI...

  • Article
  • Open Access
3 Citations
1,965 Views
14 Pages

Evaluation of Dynamic Contrast-Enhanced and Oxygen-Enhanced Functional Lung Magnetic Resonance Imaging in Chronic Obstructive Pulmonary Disease Patients

  • Rohit K. Srinivas,
  • Mandeep Garg,
  • Uma Debi,
  • Nidhi Prabhakar,
  • Sahajal Dhooria,
  • Ritesh Agarwal,
  • Ashutosh Nath Aggarwal and
  • Manavjit Singh Sandhu

23 November 2023

Chronic obstructive pulmonary disease (COPD) is a chronic respiratory condition characterized by obstruction of airways and emphysematous lung tissue damage, with associated hypoxic vasoconstriction in the affected lung parenchyma. In our study, we e...

  • Article
  • Open Access
5 Citations
2,501 Views
14 Pages

6 March 2021

The aim of the present study was to identify whether the quantitative metrics from pre-treatment (TX) non-Gaussian intravoxel incoherent motion (NGIVIM) diffusion weighted (DW-) and fast exchange regime (FXR) dynamic contrast enhanced (DCE)-MRI can p...

  • Article
  • Open Access
4 Citations
6,561 Views
9 Pages

Interobserver and Intraobserver Reproducibility with Volume Dynamic Contrast Enhanced Computed Tomography (DCE-CT) in Gastroesophageal Junction Cancer

  • Martin Lundsgaard Hansen,
  • Eva Fallentin,
  • Thomas Axelsen,
  • Carsten Lauridsen,
  • Rikke Norling,
  • Lars Bo Svendsen and
  • Michael Bachmann Nielsen

The purpose of this study was to assess inter- and intra-observer reproducibility of three different analytic methods to evaluate quantitative dynamic contrast-enhanced computed tomography (DCE-CT) measures from gastroesophageal junctional cancer. Tw...

  • Article
  • Open Access
1 Citations
2,402 Views
20 Pages

Comparison of Early Contrast Enhancement Models in Ultrafast Dynamic Contrast-Enhanced Magnetic Resonance Imaging of Prostate Cancer

  • Alfredo Clemente,
  • Guerino Selva,
  • Michael Berks,
  • Federica Morrone,
  • Aniello Alessandro Morrone,
  • Michele De Cristofaro Aulisa,
  • Ekaterina Bliakharskaia,
  • Andrea De Nicola,
  • Armando Tartaro and
  • Paul E. Summers

Tofts models have failed to produce reliable quantitative markers for prostate cancer. We examined the differences between prostate zones and lesion PI-RADS categories and grade group (GG) using regions of interest drawn in tumor and normal-appearing...

  • Article
  • Open Access
5 Citations
2,968 Views
18 Pages

Assessing Tumour Haemodynamic Heterogeneity and Response to Choline Kinase Inhibition Using Clustered Dynamic Contrast Enhanced MRI Parameters in Rodent Models of Glioblastoma

  • Sourav Bhaduri,
  • Clémentine Lesbats,
  • Jack Sharkey,
  • Claire Louise Kelly,
  • Soham Mukherjee,
  • Arthur Taylor,
  • Edward J. Delikatny,
  • Sungheon G. Kim and
  • Harish Poptani

26 February 2022

To investigate the utility of DCE-MRI derived pharmacokinetic parameters in evaluating tumour haemodynamic heterogeneity and treatment response in rodent models of glioblastoma, imaging was performed on intracranial F98 and GL261 glioblastoma bearing...

  • Review
  • Open Access
7 Citations
8,869 Views
15 Pages

Dynamic Contrast-Enhanced CT in Patients with Pancreatic Cancer

  • Rie Ø. Eriksen,
  • Louise S. Strauch,
  • Michael Sandgaard,
  • Thomas S. Kristensen,
  • Michael B. Nielsen and
  • Carsten A. Lauridsen

The aim of this systematic review is to provide an overview of the use of Dynamic Contrast-enhanced Computed Tomography (DCE-CT) in patients with pancreatic cancer. This study was composed according to the PRISMA guidelines 2009. The literature searc...

  • Review
  • Open Access
37 Citations
4,304 Views
11 Pages

Contrast-Enhanced Ultrasound for Monitoring Treatment Response in Different Stages of Hepatocellular Carcinoma

  • Mariella Faccia,
  • Matteo Garcovich,
  • Maria Elena Ainora,
  • Laura Riccardi,
  • Maurizio Pompili,
  • Antonio Gasbarrini and
  • Maria Assunta Zocco

18 January 2022

The capacity of contrast-enhanced ultrasound (CEUS) to detect microvessel perfusion has received much attention in cancer imaging since it can be used to evaluate the enhancement patterns of the lesions during all vascular phases in real time, with h...

  • Brief Report
  • Open Access
1,425 Views
8 Pages

Application of Differential Subsampling with Cartesian Ordering in Evaluating Left Ovarian Venous Reflux for Pretreatment Planning for Pelvic Venous Disorders

  • Sheida Ebrahimi,
  • Nawal Siddiqui,
  • Alexandra Besser,
  • Ana E. Rodriguez-Soto,
  • Hon Yu,
  • Christine Boone,
  • Albert Hsiao,
  • Anne C. Roberts,
  • Rupal Parikh and
  • Rebecca Rakow-Penner

10 August 2024

The diagnosis of a common cause of chronic pelvic pain can be made by visualizing reflux in the ovarian veins. Fluoroscopic venography is the gold standard for diagnosing ovarian vein reflux, but it is an invasive technique that exposes patients to i...

  • Article
  • Open Access
7 Citations
3,884 Views
11 Pages

Prediction of Lung Shunt Fraction for Yttrium-90 Treatment of Hepatic Tumors Using Dynamic Contrast Enhanced MRI with Quantitative Perfusion Processing

  • Qihao Zhang,
  • Kyungmouk Steve Lee,
  • Adam D. Talenfeld,
  • Pascal Spincemaille,
  • Martin R. Prince and
  • Yi Wang

3 November 2022

There is no noninvasive method to estimate lung shunting fraction (LSF) in patients with liver tumors undergoing Yttrium-90 (Y90) therapy. We propose to predict LSF from noninvasive dynamic contrast enhanced (DCE) MRI using perfusion quantification....

  • Article
  • Open Access
1 Citations
1,943 Views
13 Pages

Quantitative Dynamic Contrast-Enhanced Magnetic Resonance Parameters Could Predict International Society of Urological Pathology Risk Groups of Prostate Cancers on Radical Prostatectomy

  • Chun-Bi Chang,
  • Yu-Chun Lin,
  • Yon-Cheong Wong,
  • Shin-Nan Lin,
  • Chien-Yuan Lin,
  • Yu-Han Lin,
  • Ting-Wen Sheng,
  • Lan-Yan Yang and
  • Li-Jen Wang

21 September 2023

Background: The International Society of Urological Pathology (ISUP) grade and positive surgical margins (PSMs) after radical prostatectomy (RP) may reflect the prognosis of prostate cancer (PCa) patients. This study aimed to investigate whether DCE-...

  • Review
  • Open Access
37 Citations
10,313 Views
27 Pages

7 November 2012

Antivascular treatments can either be antiangiogenic or targeting established tumour vasculature. These treatments affect the tumour microvasculature and microenvironment but may not change clinical measures like tumour volume and growth. In research...

  • Article
  • Open Access
7 Citations
6,423 Views
9 Pages

Our purpose in this study was to assess the relationship between contrast signal intensity (CI) and concentration of perflubutane microbubbles in a phantom experiment, and to examine the feasibility of this technique for quantitative analysis of vasc...

  • Article
  • Open Access
14 Citations
3,038 Views
16 Pages

Algorithm Research on Detail and Contrast Enhancement of High Dynamic Infrared Images

  • Duo Zhang,
  • Yinnian Liu,
  • Yun Zhao,
  • Jian Liang,
  • Boyuan Sun and
  • Shibing Chu

24 November 2023

Infrared images have the advantages of being employed in all weather conditions and exhibiting strong anti-interference abilities and are widely used in many fields. However, there are also problems of low contrast, high noise and blurred details, fo...

  • Article
  • Open Access
140 Views
15 Pages

Diffmap: Enhancement Difference Map for Peripheral Prostate Zone Cancer Localization Based on Functional Data Analysis and Dynamic Contrast Enhancement MRI

  • Roman Surkant,
  • Jurgita Markevičiūtė,
  • Ieva Naruševičiūtė,
  • Mantas Trakymas,
  • Povilas Treigys and
  • Jolita Bernatavičienė

Dynamic contrast-enhancement (DCE) modality of MRI is typically considered secondary in prostate cancer (PCa) diagnostics, due to the common interpretation that its diagnostic power is lower than that of other modalities like T2-weighted (T2W) or dif...

  • Article
  • Open Access
1 Citations
2,859 Views
23 Pages

Characterizing Breast Tumor Heterogeneity Through IVIM-DWI Parameters and Signal Decay Analysis

  • Si-Wa Chan,
  • Chun-An Lin,
  • Yen-Chieh Ouyang,
  • Guan-Yuan Chen,
  • Chein-I Chang,
  • Chin-Yao Lin,
  • Chih-Chiang Hung,
  • Chih-Yean Lum,
  • Kuo-Chung Wang and
  • Ming-Cheng Liu

Background/Objectives: This research presents a novel analytical method for breast tumor characterization and tissue classification by leveraging intravoxel incoherent motion diffusion-weighted imaging (IVIM-DWI) combined with hyperspectral imaging t...

  • Article
  • Open Access
1,544 Views
11 Pages

Background/Objectives: The degree of vascularization of myomas plays an important role in both diagnosis and the selection of appropriate treatment. This is particularly relevant for minimally invasive therapies such as uterine artery embolization (U...

  • Article
  • Open Access
12 Citations
3,910 Views
20 Pages

9 November 2022

Background: This study aimed to reveal the heterogeneity of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) of breast cancer (BC) and identify its prognosis values and molecular characteristics. Methods: Two radiogenomics cohorts (n =...

  • Article
  • Open Access
19 Citations
3,564 Views
11 Pages

Granulomatous Prostatitis, the Great Mimicker of Prostate Cancer: Can Multiparametric MRI Features Help in This Challenging Differential Diagnosis?

  • Elena Bertelli,
  • Giulia Zantonelli,
  • Alberto Cinelli,
  • Sandro Pastacaldi,
  • Simone Agostini,
  • Emanuele Neri and
  • Vittorio Miele

23 September 2022

Clinico-radiological presentation of granulomatous prostatitis (GP) is quite similar to cancer, and differential diagnosis can be very challenging. The study aims to highlight GP features based on clinical findings and multiparametric magnetic resona...

  • Review
  • Open Access
16 Citations
3,467 Views
8 Pages

Lymphatic Phenotype of Noonan Syndrome: Innovative Diagnosis and Possible Implications for Therapy

  • Lotte E. R. Kleimeier,
  • Caroline van Schaik,
  • Erika Leenders,
  • Maxim Itkin,
  • Willemijn M. Klein and
  • Jos M. T. Draaisma

31 May 2022

Dysregulation of the Ras/Mitogen-activated protein kinase (MAPK) signaling pathway is suggested to play a pivotal role in the development of the lymphatic system in patients with Noonan Syndrome (NS). Pathogenic gene variants in the Ras/MAPK pathway...

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